JPWO2022107463A1 - - Google Patents
Info
- Publication number
- JPWO2022107463A1 JPWO2022107463A1 JP2022563613A JP2022563613A JPWO2022107463A1 JP WO2022107463 A1 JPWO2022107463 A1 JP WO2022107463A1 JP 2022563613 A JP2022563613 A JP 2022563613A JP 2022563613 A JP2022563613 A JP 2022563613A JP WO2022107463 A1 JPWO2022107463 A1 JP WO2022107463A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B49/00—Grignard reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/518—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of sulfur-containing compounds to >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/317—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020192037 | 2020-11-18 | ||
| JP2020192037 | 2020-11-18 | ||
| JP2021098285 | 2021-06-11 | ||
| JP2021098285 | 2021-06-11 | ||
| PCT/JP2021/036517 WO2022107463A1 (ja) | 2020-11-18 | 2021-10-01 | ケトン誘導体の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2022107463A1 true JPWO2022107463A1 (https=) | 2022-05-27 |
| JPWO2022107463A5 JPWO2022107463A5 (https=) | 2023-10-06 |
| JP7738857B2 JP7738857B2 (ja) | 2025-09-16 |
Family
ID=81708910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022563613A Active JP7738857B2 (ja) | 2020-11-18 | 2021-10-01 | ケトン誘導体の製造方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20240025873A1 (https=) |
| EP (1) | EP4249462A4 (https=) |
| JP (1) | JP7738857B2 (https=) |
| WO (1) | WO2022107463A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2023080243A1 (https=) * | 2021-11-08 | 2023-05-11 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016098016A1 (en) * | 2014-12-17 | 2016-06-23 | Dr. Reddy’S Laboratories Limited | Process for the preparation of sglt2 inhibitors |
| CN107311914A (zh) * | 2017-08-14 | 2017-11-03 | 苏州信恩医药科技有限公司 | 一种罗拉匹坦中间体的合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9056850B2 (en) | 2008-10-17 | 2015-06-16 | Janssen Pharmaceutica N.V. | Process for the preparation of compounds useful as inhibitors of SGLT |
| BR122020020745B8 (pt) | 2010-07-22 | 2023-10-31 | Gilead Sciences Inc | Composto antiviral para o tratamento de infecções por paramyxoviridae e composição farmacêutica que o compreende |
| JP5646706B2 (ja) | 2013-07-24 | 2014-12-24 | 壽製薬株式会社 | Ｃ−グリコシド誘導体の製造方法 |
-
2021
- 2021-10-01 JP JP2022563613A patent/JP7738857B2/ja active Active
- 2021-10-01 WO PCT/JP2021/036517 patent/WO2022107463A1/ja not_active Ceased
- 2021-10-01 US US18/037,217 patent/US20240025873A1/en active Pending
- 2021-10-01 EP EP21894338.9A patent/EP4249462A4/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016098016A1 (en) * | 2014-12-17 | 2016-06-23 | Dr. Reddy’S Laboratories Limited | Process for the preparation of sglt2 inhibitors |
| CN107311914A (zh) * | 2017-08-14 | 2017-11-03 | 苏州信恩医药科技有限公司 | 一种罗拉匹坦中间体的合成方法 |
Non-Patent Citations (7)
| Title |
|---|
| AMOAH,E. ET AL: "Regioselective 1,4-Conjugate Addition of Grignard Reagents to α,β-γ,δ-Dienones and α,β-γ,δ-D", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 82, no. 6, JPN6022048663, 2017, pages 2870 - 2888, XP093063448, ISSN: 0005581845, DOI: 10.1021/acs.joc.6b02769 * |
| BOWLES, P ET AL., ORGANIC PROCESS RESEARCH & DEVELOPMENT, vol. 18, JPN6021044620, 2014, pages 66 - 81, ISSN: 0005581848 * |
| GARCIA,J. ET AL: "Evaluation of Solution and Solid-Phase Approaches to the Synthesis of Libraries of α,α-Disubstitut", JOURNAL OF COMBINATORIAL CHEMISTRY, vol. 7, no. 6, JPN6021044621, 2005, pages 843 - 863, XP055071484, ISSN: 0005581847, DOI: 10.1021/cc0500396 * |
| LI,C. ET AL, ORGANIC LETTERS, vol. 21, no. 20, JPN6022048665, 2019, pages 8383 - 8388, ISSN: 0005581851 * |
| NAKAHARA,Y. ET AL: "An efficient synthesis of 2-acylpyrroles", AGRICULTURAL AND BIOLOGICAL CHEMISTRY, vol. 49, no. 5, JPN6021044622, 1985, pages 1491 - 1495, XP055931571, ISSN: 0005581846 * |
| 中村栄一 他: "有機銅試薬を用いた合成反応", 有機合成化学協会誌, vol. 49巻，10号, JPN6021044619, 1991, pages 902 - 908, ISSN: 0005581849 * |
| 前川智弘 他: "Gilman試薬", 有機合成化学協会誌, vol. 71巻，７号, JPN6021044618, 2013, pages 731, ISSN: 0005581850 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4249462A4 (en) | 2024-10-16 |
| WO2022107463A1 (ja) | 2022-05-27 |
| EP4249462A1 (en) | 2023-09-27 |
| JP7738857B2 (ja) | 2025-09-16 |
| US20240025873A1 (en) | 2024-01-25 |
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