JPWO2022104288A5 - - Google Patents
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- JPWO2022104288A5 JPWO2022104288A5 JP2023526396A JP2023526396A JPWO2022104288A5 JP WO2022104288 A5 JPWO2022104288 A5 JP WO2022104288A5 JP 2023526396 A JP2023526396 A JP 2023526396A JP 2023526396 A JP2023526396 A JP 2023526396A JP WO2022104288 A5 JPWO2022104288 A5 JP WO2022104288A5
- Authority
- JP
- Japan
- Prior art keywords
- neuromelanin
- scan
- time point
- mri
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 19
- 210000000627 locus coeruleus Anatomy 0.000 claims 15
- 208000024827 Alzheimer disease Diseases 0.000 claims 13
- 238000004458 analytical method Methods 0.000 claims 13
- 210000004556 brain Anatomy 0.000 claims 11
- 238000002595 magnetic resonance imaging Methods 0.000 claims 11
- 201000001119 neuropathy Diseases 0.000 claims 7
- 230000007823 neuropathy Effects 0.000 claims 7
- 208000033808 peripheral neuropathy Diseases 0.000 claims 7
- 238000011282 treatment Methods 0.000 claims 7
- 238000003745 diagnosis Methods 0.000 claims 6
- 230000011218 segmentation Effects 0.000 claims 6
- 238000003384 imaging method Methods 0.000 claims 5
- 238000005259 measurement Methods 0.000 claims 5
- 238000004393 prognosis Methods 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 238000001727 in vivo Methods 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- 241001573498 Compacta Species 0.000 claims 2
- 208000012902 Nervous system disease Diseases 0.000 claims 2
- 230000002411 adverse Effects 0.000 claims 2
- 238000011283 initial treatment period Methods 0.000 claims 2
- 238000001228 spectrum Methods 0.000 claims 2
- 210000003523 substantia nigra Anatomy 0.000 claims 2
- 229940124717 Alzheimer's therapeutics Drugs 0.000 claims 1
- 208000031124 Dementia Alzheimer type Diseases 0.000 claims 1
- 208000016285 Movement disease Diseases 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000000926 neurological effect Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000011285 therapeutic regimen Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025273972A JP2026066253A (ja) | 2020-11-16 | 2025-12-22 | ニューロメラニン感受性ｍｒｉ及びその使用方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063114304P | 2020-11-16 | 2020-11-16 | |
| US63/114,304 | 2020-11-16 | ||
| US202063120105P | 2020-12-01 | 2020-12-01 | |
| US63/120,105 | 2020-12-01 | ||
| US202163277490P | 2021-11-09 | 2021-11-09 | |
| US63/277,490 | 2021-11-09 | ||
| PCT/US2021/059590 WO2022104288A1 (en) | 2020-11-16 | 2021-11-16 | Neuromelanin-sensitive mri and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025273972A Division JP2026066253A (ja) | 2020-11-16 | 2025-12-22 | ニューロメラニン感受性ｍｒｉ及びその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023549712A JP2023549712A (ja) | 2023-11-29 |
| JPWO2022104288A5 true JPWO2022104288A5 (https=) | 2024-11-26 |
| JP2023549712A5 JP2023549712A5 (https=) | 2024-11-26 |
Family
ID=81602654
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023526396A Pending JP2023549712A (ja) | 2020-11-16 | 2021-11-16 | ニューロメラニン感受性ｍｒｉ及びその使用方法 |
| JP2025273972A Pending JP2026066253A (ja) | 2020-11-16 | 2025-12-22 | ニューロメラニン感受性ｍｒｉ及びその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025273972A Pending JP2026066253A (ja) | 2020-11-16 | 2025-12-22 | ニューロメラニン感受性ｍｒｉ及びその使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230389854A1 (https=) |
| EP (1) | EP4243684A4 (https=) |
| JP (2) | JP2023549712A (https=) |
| KR (1) | KR20230131180A (https=) |
| AU (1) | AU2021377338A1 (https=) |
| CA (1) | CA3199469A1 (https=) |
| IL (1) | IL302831A (https=) |
| MX (1) | MX2023005649A (https=) |
| WO (1) | WO2022104288A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230281804A1 (en) * | 2020-07-31 | 2023-09-07 | Koninklijke Philips N.V. | Landmark detection in medical images |
| JP2024510080A (ja) | 2021-03-11 | 2024-03-06 | テラン バイオサイエンシズ インコーポレイテッド | バイオマーカーを含む撮像データセットのハーモナイゼーションのためのシステム、デバイス及び方法 |
| TW202333668A (zh) | 2021-12-15 | 2023-09-01 | 美商德利克斯醫療公司 | 經苯氧基及苄氧基取代之精神成形素(psychoplastogen)及其用途 |
| WO2023235766A2 (en) * | 2022-05-31 | 2023-12-07 | University Of Ottawa Institute Of Mental Health Research | Methods for acquiring and analyzing neuromelanin-sensitive mri |
| CN117095815B (zh) * | 2023-07-20 | 2025-05-27 | 中国人民解放军海军军医大学第一附属医院 | 基于磁共振图像和病理全景扫描切片预测带有同源重组缺陷的前列腺癌患者的系统 |
| CN117078638A (zh) * | 2023-08-22 | 2023-11-17 | 深圳湾实验室 | 一种图像处理方法、装置及电子设备 |
| TWI877875B (zh) * | 2023-10-31 | 2025-03-21 | 中國醫藥大學附設醫院 | 腦部斷層掃描電腦輔助偵測系統、方法及電腦程式產品 |
| CN117690537B (zh) * | 2024-02-04 | 2024-06-18 | 中日友好医院(中日友好临床医学研究所) | Qsm与脑萎缩、脑连接组关联的跨模态方法及装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6288545B1 (en) * | 1999-03-22 | 2001-09-11 | General Electric Company | Method and apparatus for calibration of RF and gradient field time delays |
| EP2844143B1 (en) * | 2012-05-04 | 2023-07-19 | Emory University | Method for imaging and determining information associated with regions of the brain |
| KR102025356B1 (ko) * | 2017-11-17 | 2019-09-25 | 울산과학기술원 | 뇌에 존재하는 철의 시각화를 위한 방법 |
| EP3766042B1 (en) * | 2018-03-14 | 2025-05-07 | Emory University | Systems and methods for generating biomarkers based on multivariate mri and multimodality classifiers for disorder diagnosis |
| EP3863505A4 (en) * | 2018-10-10 | 2022-08-17 | The Trustees of Columbia University in the City of New York | SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR NEUROMELANINSENSITIVE MAGNETIC RESONANCE IMAGING AS A NON-INVASIVE PROXY MEASURE OF DOPAMINE FUNCTION IN THE HUMAN BRAIN |
| CN111681184B (zh) * | 2020-06-09 | 2023-02-24 | 复旦大学附属华山医院 | 一种神经黑色素图像重建方法、装置、设备和存储介质 |
-
2021
- 2021-11-16 JP JP2023526396A patent/JP2023549712A/ja active Pending
- 2021-11-16 CA CA3199469A patent/CA3199469A1/en active Pending
- 2021-11-16 MX MX2023005649A patent/MX2023005649A/es unknown
- 2021-11-16 IL IL302831A patent/IL302831A/en unknown
- 2021-11-16 KR KR1020237020192A patent/KR20230131180A/ko active Pending
- 2021-11-16 EP EP21893038.6A patent/EP4243684A4/en active Pending
- 2021-11-16 AU AU2021377338A patent/AU2021377338A1/en not_active Abandoned
- 2021-11-16 WO PCT/US2021/059590 patent/WO2022104288A1/en not_active Ceased
-
2023
- 2023-05-15 US US18/317,824 patent/US20230389854A1/en active Pending
-
2025
- 2025-12-22 JP JP2025273972A patent/JP2026066253A/ja active Pending
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