JPWO2021235293A1 - - Google Patents

Info

Publication number
JPWO2021235293A1
JPWO2021235293A1 JP2022524409A JP2022524409A JPWO2021235293A1 JP WO2021235293 A1 JPWO2021235293 A1 JP WO2021235293A1 JP 2022524409 A JP2022524409 A JP 2022524409A JP 2022524409 A JP2022524409 A JP 2022524409A JP WO2021235293 A1 JPWO2021235293 A1 JP WO2021235293A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022524409A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2021235293A1 publication Critical patent/JPWO2021235293A1/ja
Priority to JP2026001566A priority Critical patent/JP2026065050A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2022524409A 2020-05-20 2021-05-12 Pending JPWO2021235293A1 (cg-RX-API-DMAC7.html)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2026001566A JP2026065050A (ja) 2020-05-20 2026-01-07 Ｃｕｇリピート配列の結合剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020088499 2020-05-20
PCT/JP2021/018079 WO2021235293A1 (ja) 2020-05-20 2021-05-12 Ｃｕｇリピート配列の結合剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2026001566A Division JP2026065050A (ja) 2020-05-20 2026-01-07 Ｃｕｇリピート配列の結合剤

Publications (1)

Publication Number Publication Date
JPWO2021235293A1 true JPWO2021235293A1 (cg-RX-API-DMAC7.html) 2021-11-25

Family

ID=78708927

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022524409A Pending JPWO2021235293A1 (cg-RX-API-DMAC7.html) 2020-05-20 2021-05-12
JP2026001566A Pending JP2026065050A (ja) 2020-05-20 2026-01-07 Ｃｕｇリピート配列の結合剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2026001566A Pending JP2026065050A (ja) 2020-05-20 2026-01-07 Ｃｕｇリピート配列の結合剤

Country Status (4)

Country Link
US (1) US20230193265A1 (cg-RX-API-DMAC7.html)
EP (1) EP4154886A4 (cg-RX-API-DMAC7.html)
JP (2) JPWO2021235293A1 (cg-RX-API-DMAC7.html)
WO (1) WO2021235293A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250281571A1 (en) * 2021-04-30 2025-09-11 Osaka University Therapeutic drug for myotonic dystrophy type 1

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140050778A1 (en) * 2010-12-28 2014-02-20 University Of Rochester Nucleic acid binding compounds, methods of making, and use thereof
US20160206753A1 (en) * 2013-08-29 2016-07-21 The Scripps Research Institute Modularly assembled small molecules for the treatment of myotonic dystrophy type 1
JP2019514938A (ja) * 2016-04-27 2019-06-06 サミュメッド リミテッド ライアビリティ カンパニー イソキノリン−３イル−カルボキサミドならびにその調製および使用の方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008089307A2 (en) * 2007-01-18 2008-07-24 Lexicon Pharmaceuticals, Inc. Delta 5 desaturase inhibitors for the treatment of pain, inflammation and cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140050778A1 (en) * 2010-12-28 2014-02-20 University Of Rochester Nucleic acid binding compounds, methods of making, and use thereof
US20160206753A1 (en) * 2013-08-29 2016-07-21 The Scripps Research Institute Modularly assembled small molecules for the treatment of myotonic dystrophy type 1
JP2019514938A (ja) * 2016-04-27 2019-06-06 サミュメッド リミテッド ライアビリティ カンパニー イソキノリン−３イル−カルボキサミドならびにその調製および使用の方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
LOPEZ-MORATO M. ET AL.: "Small Molecules Which Improve Pathogenesis of Myotonic Dystrophy Type 1", FRONTIERS IN NEUROLOGY, vol. 9, JPN6021020916, 2018, pages 349, ISSN: 0005567687 *
MATSUMOTO J. ET AL.: "The Dimeric Form of 1,3-Diaminoisoquinoline Derivative Rescued the Mis-splicing of Atp2a1 and Clcn1", CHEMISTRY-A EUROPIAN JOURNAL, vol. 26, JPN6021020920, 25 May 2020 (2020-05-25), pages 14305 - 14309, ISSN: 0005567689 *
REDDY K. ET AL.: "Mitigating RNA Toxicity in Myotonic Dystrophy using Small Molecules", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, JPN6021020918, 2019, pages 4017, ISSN: 0005567688 *
VO T. ET AL.: "Biosensor-surface plasmon resonance: A strategy to help establish a new generation RNA-specific smal", METHODS, vol. 167, JPN6021020914, 2019, pages 15 - 27, ISSN: 0005567686 *

Also Published As

Publication number Publication date
EP4154886A4 (en) 2023-11-08
US20230193265A1 (en) 2023-06-22
WO2021235293A1 (ja) 2021-11-25
EP4154886A1 (en) 2023-03-29
JP2026065050A (ja) 2026-04-14

Similar Documents

Publication Publication Date Title
CN305853321S (zh) 玩具枪（恐龙214）
CN305874837S (zh) 糖果收纳盒（钻石六格）
CN305853384S (zh) 乒乓球训练器（1）
CN305873327S (zh) 收纳盒（1）
CN305857267S (zh) 吸管杯（小红帽1）
CN305867856S (zh) 漂移车（熊猫）
CN305856227S (zh) 平板电脑保护套
CN305790203S (zh) 地面清浩设备用的电机
CN305850972S (zh) 车载充电器（鹅颈式）
CN305788184S (zh) 包装盒（百家宴-珍藏181）
CN305856192S (zh) 笔袋
CN305788476S (zh) 糖果包装袋（港式珍珠奶茶）
CN305855353S (zh) 梳妆用品（懂我）
CN305800391S (zh) 吊坠（f形）
CN305856405S (zh) 洗头刷
CN305816009S (zh) 架几矮柜(十抽l型春在-大观系列)
CN305675917S (zh) 电视柜
CN305871163S (zh) 纸巾架（j910053bh）
CN305860618S (zh) 清洁机（洗吹两用）
CN305665425S (zh) 背包（a2-gry01）
CN305642693S (zh) 沙发（3663）
CN305746215S (zh) 浴缸（带扶手超高方形圆角2）
CN305662914S (zh) 花洒龙头
CN305676561S (zh) 筷子盒
CN305864984S (zh) 穿衣镜

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20240401

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20241226

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250408

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250606

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20251007

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20260107

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20260512

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20260708