JPWO2021231572A5 - - Google Patents

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Publication number
JPWO2021231572A5
JPWO2021231572A5 JP2022568792A JP2022568792A JPWO2021231572A5 JP WO2021231572 A5 JPWO2021231572 A5 JP WO2021231572A5 JP 2022568792 A JP2022568792 A JP 2022568792A JP 2022568792 A JP2022568792 A JP 2022568792A JP WO2021231572 A5 JPWO2021231572 A5 JP WO2021231572A5
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JP
Japan
Prior art keywords
alkyl
optionally substituted
halogen
carbocycle
membered heterocycle
Prior art date
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Application number
JP2022568792A
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English (en)
Japanese (ja)
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JP2023526247A (ja
JP2023526247A5 (https=
JP7758687B2 (ja
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Priority claimed from PCT/US2021/031989 external-priority patent/WO2021231572A1/en
Publication of JP2023526247A publication Critical patent/JP2023526247A/ja
Publication of JP2023526247A5 publication Critical patent/JP2023526247A5/ja
Publication of JPWO2021231572A5 publication Critical patent/JPWO2021231572A5/ja
Application granted granted Critical
Publication of JP7758687B2 publication Critical patent/JP7758687B2/ja
Active legal-status Critical Current
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JP2022568792A 2020-05-13 2021-05-12 神経筋疾患の処置のためのピリダジノン化合物 Active JP7758687B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063024442P 2020-05-13 2020-05-13
US63/024,442 2020-05-13
PCT/US2021/031989 WO2021231572A1 (en) 2020-05-13 2021-05-12 Pyridazinone compounds for the treatment of neuromuscular diseases

Publications (4)

Publication Number Publication Date
JP2023526247A JP2023526247A (ja) 2023-06-21
JP2023526247A5 JP2023526247A5 (https=) 2024-05-22
JPWO2021231572A5 true JPWO2021231572A5 (https=) 2024-05-22
JP7758687B2 JP7758687B2 (ja) 2025-10-22

Family

ID=76444536

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022568792A Active JP7758687B2 (ja) 2020-05-13 2021-05-12 神経筋疾患の処置のためのピリダジノン化合物

Country Status (4)

Country Link
US (1) US20230150977A1 (https=)
EP (1) EP4149621B1 (https=)
JP (1) JP7758687B2 (https=)
WO (1) WO2021231572A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3877376T3 (da) 2018-11-06 2023-10-02 Edgewise Therapeutics Inc Pyridazinonforbindelser og anvendelser deraf
CA3118908A1 (en) 2018-11-06 2020-05-14 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
AU2019374812B2 (en) 2018-11-06 2025-03-06 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
CN120302976A (zh) 2022-09-09 2025-07-11 艾知怀斯治疗学公司 用于治疗神经肌肉病状的哒嗪酮组合物
KR20250121977A (ko) * 2023-01-04 2025-08-12 시젱 하이스코 파마수티칼 씨오., 엘티디. 피리다지논 헤테로사이클릭 화합물 Myosin II 억제제 및 이의 용도
WO2025153721A1 (en) * 2024-01-19 2025-07-24 Scenic Biotech Bv Pla2g15 inhibitors
WO2025167826A1 (zh) * 2024-02-06 2025-08-14 西藏海思科制药有限公司 三环化合物作为Myosin II抑制剂及其用途
WO2025175141A1 (en) * 2024-02-16 2025-08-21 Cytokinetics, Incorporated Fast skeletal muscle myosin inhibitors
WO2025242154A1 (zh) * 2024-05-23 2025-11-27 西藏海思科制药有限公司 哒嗪酮衍生物及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6334997B1 (en) 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
CN1087725C (zh) 1994-03-25 2002-07-17 同位素技术有限公司 用氘代方法增强药物效果
NZ522882A (en) * 2000-06-05 2004-07-30 Altana Pharma Bv Pyridazinone compounds effective as beta-2-adrenoreceptor agonists as well as PDE4-inhibitors
UA95644C2 (ru) * 2006-07-25 2011-08-25 Сефалон, Инк. Пиридазиноновые производные, фармацевтическая композиция и способ лечения заболеваний
AU2008219166B2 (en) * 2007-02-16 2013-05-16 Amgen Inc. Nitrogen-containing heterocyclyl ketones and their use as c-Met inhibitors
AR081331A1 (es) * 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
US8759380B2 (en) * 2011-04-22 2014-06-24 Cytokinetics, Inc. Certain heterocycles, compositions thereof, and methods for their use
EP3600322A1 (en) * 2017-03-28 2020-02-05 Boehringer Ingelheim International GmbH Nintedanib for use in methods for the treatment of muscular dystrophy
EP3700516B1 (en) * 2017-10-27 2024-01-24 Sonic Master Limited Inhibitors of dux4 induction for regulation of muscle function
EP4685140A1 (en) * 2018-06-04 2026-01-28 Ohio State Innovation Foundation Eaat2 activators and methods of using thereof
CA3118908A1 (en) * 2018-11-06 2020-05-14 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
AU2019374812B2 (en) * 2018-11-06 2025-03-06 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
DK3877376T3 (da) * 2018-11-06 2023-10-02 Edgewise Therapeutics Inc Pyridazinonforbindelser og anvendelser deraf

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