JPWO2021210515A1 - - Google Patents

Info

Publication number
JPWO2021210515A1
JPWO2021210515A1 JP2022515358A JP2022515358A JPWO2021210515A1 JP WO2021210515 A1 JPWO2021210515 A1 JP WO2021210515A1 JP 2022515358 A JP2022515358 A JP 2022515358A JP 2022515358 A JP2022515358 A JP 2022515358A JP WO2021210515 A1 JPWO2021210515 A1 JP WO2021210515A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022515358A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2021210515A1 publication Critical patent/JPWO2021210515A1/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2022515358A 2020-04-13 2021-04-09 Pending JPWO2021210515A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020071737 2020-04-13
PCT/JP2021/015093 WO2021210515A1 (ja) 2020-04-13 2021-04-09 腎臓中のｃｄ２５陽性の制御性ｔ細胞増加剤

Publications (1)

Publication Number Publication Date
JPWO2021210515A1 true JPWO2021210515A1 (https=) 2021-10-21

Family

ID=78084239

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022515358A Pending JPWO2021210515A1 (https=) 2020-04-13 2021-04-09

Country Status (5)

Country Link
US (1) US20230158076A1 (https=)
EP (1) EP4137141A4 (https=)
JP (1) JPWO2021210515A1 (https=)
CN (1) CN115297877A (https=)
WO (1) WO2021210515A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011043136A1 (ja) * 2009-10-08 2011-04-14 国立大学法人名古屋大学 脂肪組織由来間葉系幹細胞を含有する免疫抑制剤及びその用途
JP2014139214A (ja) * 2006-10-02 2014-07-31 Mesoblast International Srl 間葉系幹細胞とその用途
JP2015500810A (ja) * 2011-11-30 2015-01-08 アドバンスド セル テクノロジー、インコーポレイテッド 間葉系間質細胞及びその関連用途
JP2019510042A (ja) * 2016-03-28 2019-04-11 クック・ジェネラル・バイオテクノロジー・エルエルシー 生細胞組成物及び生細胞組成物に関連する方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2730497A (en) * 1996-04-17 1997-11-07 Case Western Reserve University Cryopreservation and extensive subculturing of human mesenchymal stem cells
US6777231B1 (en) 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
EP3461884B1 (en) * 2004-03-22 2025-05-28 Mesoblast International Sàrl Mesenchymal stem cells and uses therefor
EP3419635B1 (en) * 2016-02-22 2022-01-05 Centauri Biotech, S.L. Pharmaceutical or veterinary cell compositions comprising mesenchymal stromal cells (mscs) and dimethyl sulfoxide (dmso)
SG10201912046VA (en) * 2016-02-26 2020-02-27 Scm Lifescience Co Ltd Pharmaceutical composition for preventing or treating regulatory t cell-mediated diseases
WO2018159432A1 (ja) * 2017-03-03 2018-09-07 ロート製薬株式会社 間葉系幹細胞及び医薬組成物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014139214A (ja) * 2006-10-02 2014-07-31 Mesoblast International Srl 間葉系幹細胞とその用途
WO2011043136A1 (ja) * 2009-10-08 2011-04-14 国立大学法人名古屋大学 脂肪組織由来間葉系幹細胞を含有する免疫抑制剤及びその用途
JP2015500810A (ja) * 2011-11-30 2015-01-08 アドバンスド セル テクノロジー、インコーポレイテッド 間葉系間質細胞及びその関連用途
JP2019510042A (ja) * 2016-03-28 2019-04-11 クック・ジェネラル・バイオテクノロジー・エルエルシー 生細胞組成物及び生細胞組成物に関連する方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BARBADO, J., ET AL.: " Therapeutic potential of allogeneic mesenchymal stromal cells transplantation for lupus nephritis", LUPUS, vol. 27, JPN6021017667, 2018, pages 2161 - 2165, ISSN: 0005743025 *
DEMIRCAN, P. C., ET AL.: "Immunoregulatory Properties of Mesenchymal Stem Cells: In Vitro and In Vivo", STEM CELLS: CURRENT CHALLENGES AND NEW DIRECTIONS, JPN6021017671, 2013, pages 29 - 58, ISSN: 0005743027 *
THIEL, A., ET AL.: "Human embryonic stem cell-derived mesenchymal cells preserve kidney function and extend lifespan in", SCIENTIFIC REPORTS, vol. 5, no. 17685, JPN6021017669, 2015, pages 1 - 13, ISSN: 0005743026 *
古橋 和拡 ほか: "脂肪由来間葉系幹細胞を用いた腎疾患治療", 日本内科学会雑誌, vol. 109, no. 4, JPN6025049440, 10 April 2020 (2020-04-10), pages 812 - 818, ISSN: 0005743028 *

Also Published As

Publication number Publication date
WO2021210515A1 (ja) 2021-10-21
EP4137141A1 (en) 2023-02-22
CN115297877A (zh) 2022-11-04
US20230158076A1 (en) 2023-05-25
EP4137141A4 (en) 2024-04-24

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