JPWO2021157739A1 - - Google Patents

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Publication number
JPWO2021157739A1
JPWO2021157739A1 JP2021576209A JP2021576209A JPWO2021157739A1 JP WO2021157739 A1 JPWO2021157739 A1 JP WO2021157739A1 JP 2021576209 A JP2021576209 A JP 2021576209A JP 2021576209 A JP2021576209 A JP 2021576209A JP WO2021157739 A1 JPWO2021157739 A1 JP WO2021157739A1
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2021576209A
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Japanese (ja)
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JP7689737B2 (ja
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Publication of JPWO2021157739A1 publication Critical patent/JPWO2021157739A1/ja
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Publication of JP7689737B2 publication Critical patent/JP7689737B2/ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Data Mining & Analysis (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Software Systems (AREA)
  • Evolutionary Computation (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Public Health (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021576209A 2020-02-06 2021-02-06 シングルセルRNA-Seq解析のカウントデータセットの補正方法、シングルセルRNA-Seqの解析方法、細胞種の構成比率の解析方法、並びにこれらの方法を実行するための装置及びコンピュータプログラム Active JP7689737B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020018989 2020-02-06
JP2020018989 2020-02-06
PCT/JP2021/004470 WO2021157739A1 (ja) 2020-02-06 2021-02-06 シングルセルRNA-Seq解析のカウントデータセットの補正方法、シングルセルRNA-Seqの解析方法、細胞種の構成比率の解析方法、並びにこれらの方法を実行するための装置及びコンピュータプログラム

Publications (2)

Publication Number Publication Date
JPWO2021157739A1 true JPWO2021157739A1 (https=) 2021-08-12
JP7689737B2 JP7689737B2 (ja) 2025-06-09

Family

ID=77199636

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021576209A Active JP7689737B2 (ja) 2020-02-06 2021-02-06 シングルセルRNA-Seq解析のカウントデータセットの補正方法、シングルセルRNA-Seqの解析方法、細胞種の構成比率の解析方法、並びにこれらの方法を実行するための装置及びコンピュータプログラム

Country Status (6)

Country Link
US (1) US20230074644A1 (https=)
EP (1) EP4101933A4 (https=)
JP (1) JP7689737B2 (https=)
CA (1) CA3170368A1 (https=)
IL (1) IL295227A (https=)
WO (1) WO2021157739A1 (https=)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019018684A1 (en) * 2017-07-21 2019-01-24 The Board Of Trustees Of The Leland Stanford Junior University SYSTEMS AND METHODS FOR ANALYZING MIXED CELL POPULATIONS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019018684A1 (en) * 2017-07-21 2019-01-24 The Board Of Trustees Of The Leland Stanford Junior University SYSTEMS AND METHODS FOR ANALYZING MIXED CELL POPULATIONS

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KANG K. ET AL.: "CDSeq: A novel complete deconvolution method for dissecting heterogeneous samples using gene express", PLOS COMPUTATIONAL BIOLOGY, vol. Vol.15, No.12, e1007510, JPN6021013723, 2019, ISSN: 0005496873 *
MONACO G. ET AL.: "RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Ty", CELL REPORTS, vol. Vol.26, p.1627-1640, JPN6021013724, 2019, ISSN: 0005496874 *
TSOUCAS D. ET AL.: "Accurate estimation of cell-type composition from gene expression data", NATURE COMMUNICATIONS, vol. Vol.10, 2975, JPN6021013726, 2019, ISSN: 0005496875 *

Also Published As

Publication number Publication date
US20230074644A1 (en) 2023-03-09
WO2021157739A1 (ja) 2021-08-12
CA3170368A1 (en) 2021-08-12
EP4101933A4 (en) 2024-02-28
EP4101933A1 (en) 2022-12-14
IL295227A (en) 2022-10-01
JP7689737B2 (ja) 2025-06-09

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