JPWO2021140398A5

JPWO2021140398A5 -

Info

Publication number: JPWO2021140398A5
Application number: JP2022542252A
Authority: JP
Publication date: 2024-01-04

Claims

A system for use with a subject's tissue, the system comprising:
- An implant comprising a wall surrounding the lumen;
・A delivery tool,
- a catheter having a distal portion transluminally advanceable to the tissue and comprising a distal opening, the implant being configured to be delivered to the tissue via the catheter; catheter and
- an extracorporeal control assembly,
configured to advance at least a portion of the wall out of the distal opening;
operably coupled to the distal portion for steering the distal portion to place the portion of the wall in abutment against the tissue region, the portion being operably coupled to the wall; disposed distally from the portion of the section and on opposite sides of the distal opening;
an extracorporeal control assembly;
- an ultrasonic tool,
advanceable within the catheter;
an ultrasonic transceiver at a distal end of the ultrasonic tool;
configured to position the ultrasound transceiver within the lumen of the implant and facing the portion of the wall;
configured to facilitate imaging of the site by transmitting ultrasound energy through the portion of the wall and into the site;
ultrasonic tools and
a delivery tool comprising;
・Organizational anchor and
- an anchor driver configured to anchor the implant to the tissue by driving the tissue anchor through the portion of the wall and into the site;
A system equipped with.

2. The system of claim 1, wherein the catheter is configured to be advanced transfemorally and transseptally into the tissue.

3. The system of claim 1 or 2, wherein the distal portion of the catheter is radiopaque.

4. The anchor driver is configured to advance the tissue anchor through the catheter to the implant with the implant disposed in the tissue. system.

the ultrasound transceiver is configured to detect reflected ultrasound energy, the reflected ultrasound energy being a portion of the ultrasound energy transmitted by the ultrasound transceiver and reflected from the site;
The ultrasonic tool includes:
an ultrasound controller comprising circuitry and a user interface configured to facilitate analysis of the reflected ultrasound energy detected by the ultrasound transceiver;
a connector configured to relay data representing the reflected ultrasound energy detected by the ultrasound transceiver from the ultrasound transceiver to the ultrasound controller;
5. The system according to any one of claims 1 to 4, further comprising:

6. The system of claim 5, wherein the ultrasound transceiver is configured to detect reflected ultrasound energy reflected from the site through the portion of the wall.

The delivery tool further comprises an anchor channel, the anchor channel comprising:
defining a longitudinal cavity terminating in a distal aperture;
extending through the catheter such that a distal region of the anchor channel with the distal aperture is disposed within the lumen;
7. The system of any preceding claim, advanceable within the catheter and lumen.

The anchor channel is
a distal region of the anchor channel is disposed within the lumen, the distal region comprising the distal aperture;
8. The system of claim 7, wherein the anchor channel is configured to extend through the catheter to facilitate positioning of the portion of the wall at the site.

The anchor driver is
the longitudinal cavity for advancing the tissue anchor into the lumen of the implant in a manner such that the tissue anchor, when coupled to the tissue anchor, reaches the portion of the wall; can be advanced through the section to the implant;
8. The system of claim 7, wherein the system is removable from the longitudinal cavity via a proximal opening of the catheter.

The ultrasonic transceiver includes:
advanceable through the longitudinal cavity and into the lumen of the implant such that the ultrasound transceiver faces the portion of the wall;
10. The system of claim 9, wherein the system is removable from the longitudinal cavity through the proximal opening of the catheter.

11. The system of claim 10, wherein the anchor driver is advanceable through the longitudinal cavity to the implant only if the ultrasound transceiver is not disposed through the longitudinal cavity.

the ultrasonic tool comprises the anchor channel;
the ultrasound transceiver is disposed in the distal region of the anchor channel;
10. The system of claim 9, wherein the anchor channel is configured to position the ultrasound transceiver within the lumen of the implant and facing the portion of the wall.

13. The system of claim 12, wherein the ultrasound transceiver is configured as a ring, the ring defining a passageway therethrough.

The anchor driver, when coupled to the tissue anchor, is configured to advance the tissue anchor through the passageway in a manner such that the tissue anchor reaches the portion of the wall. 14. The system of claim 13, advanceable through a longitudinal cavity to the implant.

15. The system of any one of claims 1-14, wherein the implant includes an annuloplasty structure, the annuloplasty structure comprising a sleeve defined by the wall.

The annuloplasty structure further includes a contraction member and an adjustment mechanism;
the adjustment mechanism is configured to apply tension to the retractable member when actuated;
16. The system of claim 15, wherein the contraction member is configured to adjust the length of the annuloplasty structure when tensioned by actuating the adjustment mechanism.