JPWO2021067990A5

JPWO2021067990A5 -

Info

Publication number: JPWO2021067990A5
Application number: JP2022519219A
Authority: JP
Publication date: 2023-10-06

Claims

housing and
a drug storage container fixed to the housing and including an inner surface and a stopper slidable along the inner surface;
a biasing member;
a plunger operably coupled to the biasing member;
selectively rotating from an initial rotational position to a second rotational position under a biasing force applied by the biasing member;
a plunger configured to linearly translate in a distal direction after rotation from the initial rotational position to the second rotational position to drive the stopper through the drug reservoir. drug delivery device.

2. The drug delivery device of claim 1, comprising a biasing member disposed at least partially within the plunger.

3. The drug delivery device of claim 2, wherein the biasing member comprises a compression spring.

Drug delivery according to claim 2 or 3, wherein the plunger is configured to linearly translate in the distal direction while rotating from the initial rotational position towards the second rotational position. device.

A drug delivery device according to any preceding claim, comprising a plunger guide fixed relative to the housing, the plunger being at least partially disposed within the plunger guide.

6. The drug delivery device of claim 5 , wherein one of the plunger and the plunger guide comprises a cam and the other of the plunger and the plunger guide comprises a cam follower.

7. The drug delivery device of claim 6 , wherein the biasing force of the biasing member urges the cam follower against the cam to rotate the plunger from the initial rotational position toward the second rotational position.

8. The drug delivery device of claim 7 , wherein the plunger includes the cam follower, the plunger guide includes the cam, and the cam follower is formed by at least one protrusion extending outwardly from the plunger.

9. The drug delivery device of claim 8 , wherein the plunger guide comprises an annular wall and the cam is formed by a proximally facing surface of the annular wall.

a release member operably coupled to the plunger and configured for selective rotation with respect to the housing, each of the plunger and the plunger guide being at least partially disposed within the release member; a release member;
A drug delivery device according to any one of claims 5 to 9 , comprising a guard movably disposed adjacent the opening in the housing and operably coupled to the release member.

5. The guard has an extended position in which the guard extends at least partially through the opening in the housing and a retracted position in which the guard is disposed away from the extended position and toward the housing. 11. The drug delivery device according to 10 .

The release member is prevented from rotating in at least one rotational direction when the guard is in the extended position, and the release member is prevented from rotating in the at least one rotational direction when the guard is in the retracted position. 12. The drug delivery device of claim 11 , which is capable of rotation.

Moving the guard from the extended position to the retracted position causes the release member and plunger to move from the initial rotational position to the second rotational position under the biasing force applied by the biasing member. 13. A drug delivery device according to claim 11 or 12 , which is enabled to rotate together towards.

a housing having an opening;
a drug storage container including a delivery member having an insertion end configured to extend at least partially through the opening;
a guard movably disposed adjacent to the opening;
a distally movable plunger for releasing drug from the drug storage container through the delivery member;
a plunger biasing member;
a release member operably coupled to the guard and the plunger and configured to rotate from an initial rotational position to a second rotational position under a biasing force applied by the plunger biasing member; , a release member.

5. The guard has an extended position in which the guard extends at least partially through the opening in the housing and a retracted position in which the guard is disposed toward the housing away from the extended position. 15. The drug delivery device according to 14 .

The release member is prevented from rotating from the initial rotational position toward the second rotational position when the guard is in the extended position, and the release member is prevented from rotating toward the second rotational position when the guard is in the retracted position. 16. The drug delivery device of claim 15 , wherein the drug delivery device is rotatable from the initial rotational position toward the second rotational position.

Moving the guard from the extended position to the retracted position causes the release member and plunger to rotate from the initial rotational position to the second rotation under the biasing force applied by the plunger biasing member. 17. A drug delivery device according to claim 15 or 16 , which is enabled to rotate together into position.

18. A drug delivery device according to any one of claims 15 to 17 , comprising a guard extension, wherein the release member is located at least partially within the guard extension.

a first projection extending outwardly from the release member and a second projection extending inwardly from the guard extension, the first projection and the second projection engaging each other to release the release member; 19. The drug delivery device of claim 18 , wherein the member is held in the initial rotational position.

When the guard is in the retracted position, the second projection slides out of engagement with the first projection, and the release member moves from the initial rotational position toward the second rotational position. 20. The drug delivery device of claim 19 , wherein the drug delivery device is capable of rotation.

a housing having an opening;
a drug storage container including a delivery member having an insertion end configured to extend at least partially through the opening;
A plunger and
a plunger biasing member initially held in a biased state, and releasing the plunger biasing member causes the plunger to be driven distally to remove drug from the drug reservoir and into the delivery member; a plunger biasing member ejected through;
an indicator having an initial position in which the indicator holds the plunger biasing member in the biased condition and a second position in which the indicator generates an audible signal indicative of termination of drug delivery; A drug delivery device comprising:

22. The drug delivery device of claim 21 , comprising an indicator biasing member configured to bias the indicator proximally.

23. The drug delivery device of claim 22 , comprising a cam and a cam follower, and wherein the indicator comprises the cam follower.

24. The drug delivery device of claim 23 , wherein a biasing force of the indicator biasing member urges the cam follower against the cam to rotate the indicator relative to the housing.

25. The drug delivery device of claim 24 , wherein the indicator rotates relative to the housing and translates linearly in the proximal direction when moving from the initial position to the second position.