JPWO2020232109A5 - - Google Patents
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- JPWO2020232109A5 JPWO2020232109A5 JP2021568087A JP2021568087A JPWO2020232109A5 JP WO2020232109 A5 JPWO2020232109 A5 JP WO2020232109A5 JP 2021568087 A JP2021568087 A JP 2021568087A JP 2021568087 A JP2021568087 A JP 2021568087A JP WO2020232109 A5 JPWO2020232109 A5 JP WO2020232109A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence reads
- probability
- cancer
- disease state
- model
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962847223P | 2019-05-13 | 2019-05-13 | |
| US62/847,223 | 2019-05-13 | ||
| US201962855289P | 2019-05-31 | 2019-05-31 | |
| US62/855,289 | 2019-05-31 | ||
| US202063002169P | 2020-03-30 | 2020-03-30 | |
| US63/002,169 | 2020-03-30 | ||
| PCT/US2020/032657 WO2020232109A1 (en) | 2019-05-13 | 2020-05-13 | Model-based featurization and classification |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022532892A JP2022532892A (ja) | 2022-07-20 |
| JPWO2020232109A5 true JPWO2020232109A5 (de) | 2023-03-23 |
Family
ID=70919219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021568087A Pending JP2022532892A (ja) | 2019-05-13 | 2020-05-13 | モデルベースの特徴量化および分類 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20200365229A1 (de) |
| EP (1) | EP3969622A1 (de) |
| JP (1) | JP2022532892A (de) |
| CN (1) | CN113826167A (de) |
| AU (1) | AU2020274348A1 (de) |
| CA (1) | CA3136204A1 (de) |
| IL (1) | IL286874A (de) |
| TW (1) | TW202108774A (de) |
| WO (1) | WO2020232109A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202410055A (zh) | 2018-06-01 | 2024-03-01 | 美商格瑞爾有限責任公司 | 用於資料分類之卷積神經網路系統及方法 |
| EP3856903A4 (de) | 2018-09-27 | 2022-07-27 | Grail, LLC | Methylierungsmarker und gezieltes methylierungssondenpaneel |
| US11581062B2 (en) | 2018-12-10 | 2023-02-14 | Grail, Llc | Systems and methods for classifying patients with respect to multiple cancer classes |
| US11396679B2 (en) | 2019-05-31 | 2022-07-26 | Universal Diagnostics, S.L. | Detection of colorectal cancer |
| US11640552B2 (en) * | 2019-10-01 | 2023-05-02 | International Business Machines Corporation | Two stage training to obtain a best deep learning model with efficient use of computing resources |
| CN111081370B (zh) * | 2019-10-25 | 2023-11-03 | 中国科学院自动化研究所 | 一种用户分类方法及装置 |
| CN114556790A (zh) * | 2019-11-08 | 2022-05-27 | 谷歌有限责任公司 | 用于熵代码化的概率估计 |
| US11898199B2 (en) | 2019-11-11 | 2024-02-13 | Universal Diagnostics, S.A. | Detection of colorectal cancer and/or advanced adenomas |
| AU2020391488A1 (en) | 2019-11-27 | 2022-06-09 | Grail, Llc | Systems and methods for evaluating longitudinal biological feature data |
| KR20220133868A (ko) | 2019-12-13 | 2022-10-05 | 그레일, 엘엘씨 | 패치 컨볼루션 신경망을 사용한 암 분류 |
| CN115702457A (zh) | 2020-03-04 | 2023-02-14 | 格里尔公司 | 使用自动编码器确定癌症状态的系统和方法 |
| JP7384282B2 (ja) * | 2020-05-11 | 2023-11-21 | 日本電気株式会社 | 判定装置、判定方法およびプログラム |
| WO2022002424A1 (en) | 2020-06-30 | 2022-01-06 | Universal Diagnostics, S.L. | Systems and methods for detection of multiple cancer types |
| US20220065479A1 (en) * | 2020-08-28 | 2022-03-03 | Johnson Controls Tyco IP Holdings LLP | Infection control tool for hvac system |
| CN114566220A (zh) * | 2020-11-27 | 2022-05-31 | 深圳华大生命科学研究院 | 基于dna甲基化水平确定样本类型的系统、可读介质及其应用 |
| US20220333209A1 (en) * | 2021-04-06 | 2022-10-20 | Grail, Llc | Conditional tissue of origin return for localization accuracy |
| CN113033689A (zh) * | 2021-04-07 | 2021-06-25 | 新疆爱华盈通信息技术有限公司 | 图像分类方法、装置、电子设备及存储介质 |
| AU2022339065A1 (en) | 2021-09-06 | 2024-03-14 | Christian-Albrechts-Universität Zu Kiel | Method for the diagnosis and/or classification of a disease in a subject |
| IL310441A (en) * | 2021-09-20 | 2024-03-01 | Grail Llc | A plausible noise model of methylation with filtering of noisy regions |
| WO2023097278A1 (en) * | 2021-11-23 | 2023-06-01 | Grail, Llc | Sample contamination detection of contaminated fragments for cancer classification |
| WO2023107709A1 (en) * | 2021-12-10 | 2023-06-15 | Adela, Inc. | Methods and systems for generating sequencing libraries |
| CN114446474A (zh) * | 2021-12-25 | 2022-05-06 | 新瑞鹏宠物医疗集团有限公司 | 宠物疾病预警装置、方法、电子设备及存储介质 |
| WO2023158711A1 (en) * | 2022-02-17 | 2023-08-24 | Grail, Llc | Tumor fraction estimation using methylation variants |
| CN114927213A (zh) * | 2022-04-15 | 2022-08-19 | 南京世和基因生物技术股份有限公司 | 多癌种早筛模型构建方法以及检测装置 |
| CN115565608A (zh) * | 2022-06-22 | 2023-01-03 | 中国食品药品检定研究院 | 一种鉴定样本中间充质干细胞的组织来源的方法及其用途 |
| US20240021267A1 (en) * | 2022-07-18 | 2024-01-18 | Grail, Llc | Dynamically selecting sequencing subregions for cancer classification |
| WO2024030869A1 (en) | 2022-08-01 | 2024-02-08 | Grail, Llc | Systems and methods for detecting disease subtypes |
| WO2024107982A1 (en) * | 2022-11-16 | 2024-05-23 | Grail, Llc | Optimization of model-based featurization and classification |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9115386B2 (en) | 2008-09-26 | 2015-08-25 | Children's Medical Center Corporation | Selective oxidation of 5-methylcytosine by TET-family proteins |
| WO2011127136A1 (en) | 2010-04-06 | 2011-10-13 | University Of Chicago | Composition and methods related to modification of 5-hydroxymethylcytosine (5-hmc) |
| WO2014015196A2 (en) * | 2012-07-18 | 2014-01-23 | The Board Of Trustees Of The Leland Stanford Junior University | Techniques for predicting phenotype from genotype based on a whole cell computational model |
| CA2902916C (en) * | 2013-03-14 | 2018-08-28 | Mayo Foundation For Medical Education And Research | Detecting neoplasm |
| CN106460070B (zh) * | 2014-04-21 | 2021-10-08 | 纳特拉公司 | 检测染色体片段中的突变和倍性 |
| US9984201B2 (en) * | 2015-01-18 | 2018-05-29 | Youhealth Biotech, Limited | Method and system for determining cancer status |
| MY195527A (en) * | 2016-10-24 | 2023-01-30 | Grail Inc | Methods And Systems For Tumor Detection |
| MX2020001575A (es) * | 2017-08-07 | 2020-11-18 | Univ Johns Hopkins | Materiales y métodos para evaluar y tratar el cáncer. |
| WO2019079647A2 (en) * | 2017-10-18 | 2019-04-25 | Wuxi Nextcode Genomics Usa, Inc. | IA STATISTICS FOR DEEP LEARNING AND PROBABILISTIC PROGRAMMING, ADVANCED, IN BIOSCIENCES |
| US11168356B2 (en) * | 2017-11-02 | 2021-11-09 | The Chinese University Of Hong Kong | Using nucleic acid size range for noninvasive cancer detection |
| EP3775198A4 (de) | 2018-04-02 | 2022-01-05 | Grail, Inc. | Methylierungsmarker und gezielte methylierungssondenpaneele |
-
2020
- 2020-05-13 WO PCT/US2020/032657 patent/WO2020232109A1/en active Application Filing
- 2020-05-13 EP EP20729530.4A patent/EP3969622A1/de active Pending
- 2020-05-13 TW TW109115936A patent/TW202108774A/zh unknown
- 2020-05-13 CA CA3136204A patent/CA3136204A1/en active Pending
- 2020-05-13 AU AU2020274348A patent/AU2020274348A1/en active Pending
- 2020-05-13 CN CN202080036172.8A patent/CN113826167A/zh active Pending
- 2020-05-13 US US15/931,022 patent/US20200365229A1/en active Pending
- 2020-05-13 JP JP2021568087A patent/JP2022532892A/ja active Pending
-
2021
- 2021-09-30 IL IL286874A patent/IL286874A/en unknown
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