JPWO2020223433A5

JPWO2020223433A5 -

Info

Publication number: JPWO2020223433A5
Application number: JP2021564648A
Authority: JP
Publication date: 2023-05-02

Claims

an imaging probe;
an imaging assembly, and
The imaging probe is
an elongated shaft comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion;
a rotatable optical core having a proximal end and a distal end, wherein at least a portion of the rotatable optical core is disposed within the lumen of the elongate shaft;
an optical assembly positioned proximate the distal end of the rotatable optical core and configured to illuminate tissue and collect reflected light from the tissue;
a damping fluid disposed between the elongated shaft and the rotatable optical core and configured to reduce uneven rotation of the optical assembly;
a fluid pressurizing element configured to increase the pressure of the damping fluid and reduce the presence of air bubbles proximate the optical assembly;
The imaging assembly includes:
constructed and arranged to optically couple with the imaging probe and configured to emit light to the imaging probe and receive the reflected light collected by the optical assembly;
Imaging system for patient.

The fluid pressurizing element is
configured to reduce bubble formation;
The system of claim 1.

The fluid pressurizing element is
configured to reduce the size of the one or more bubbles;
The system of claim 1 .

comprising an optical beam path,
The fluid pressurizing element is
configured to propel one or more bubbles away from the optical beam path;
The system of claim 1 .

The fluid pressurizing element is
configured to create a pressure gradient within the damping fluid;
The system of claim 1 .

The fluid pressurizing element is
configured to intermittently increase the pressure of the damping fluid;
The system of claim 1 .

The fluid pressurizing element is
configured to increase the pressure of the damping fluid for discrete times of 5 seconds or less;
7. A system according to claim 6 .

The fluid pressurizing element is
configured to generate a pressure of the damping fluid that is at least 3.6 psi, 5.0 psi, 10 psi, 15 psi, 20 psi, 30 psi, 40 psi, 75 psi, 100 psi, 125 psi, and/or 150 psi;
The system of claim 1 .

The fluid pressurizing element is
configured to increase the pressure of the damping fluid when the rotatable optical core rotates;
The system of claim 1 .

The fluid pressurizing element is
a helical protrusion extending radially from the rotatable optical core;
10. System according to claim 9 .

The fluid pressurizing element is
comprising a first fluid pressurization element and a second fluid pressurization element;
The second fluid pressurizing element comprises:
located proximal to the first fluid pressurizing element;
The system of claim 1 .

The second fluid pressurizing element comprises:
configured to prime the first fluid pressurizing element when rotated;
12. The system of claim 11 .

The fluid pressurizing element is
adhesively attached to the rotatable optical core;
The system of claim 1 .

The fluid pressurizing element is
formed within the rotatable optical core;
The system of claim 1 .

The system includes:
formed on the rotatable optical core by vapor deposition and/or three-dimensional (3D) printing;
15. The system of claim 14 .

The fluid pressurizing element is
comprising a material selected from the group consisting of metal, plastic, stainless steel, nickel-titanium alloy, nylon, polyetheretherketone, polyimide, and combinations thereof;
The system of claim 1 .

The rotatable optical core comprises:
having a diameter D1,
the lumen of the elongated shaft comprising:
having a diameter D2,
The fluid pressurizing element is
extending at a radial height H1 from the rotatable optical core,
The height H1 is
is at least 5% and/or no more than 95% of half the difference between said diameter D1 and said diameter D2;
The system of claim 1 .

The rotatable optical core comprises:
having a diameter D1,
the lumen of the elongated shaft comprising:
having a diameter D2,
The fluid pressurizing element is
extending at a radial height H1 from the rotatable optical core;
Clearance C1 is
having half the difference between the diameter D1 and the diameter D2 minus the height H1;
The clearance C1 is
having a length of 100 μm or less and/or 75 μm or less;
The system of claim 1 .

The damping fluid is
comprising a shear thinning fluid;
The system of claim 1 .

The damping fluid is
having a static viscosity of at least 500 centipoises;
The system of claim 1 .

The damping fluid is
the ratio of static viscosity to shear viscosity is at least 1.2:1 and/or no more than 100:1;
21. System according to claim 20 .

The damping fluid is
comprising a low viscosity fluid configured to reduce bubble formation;
The system of claim 1 .

The damping fluid is
comprising a fluid having a viscosity of 1000 centipoise or less;
23. The system of claim 22 .

The damping fluid is
comprising a fluid having a high surface tension configured to reduce bubble formation;
The system of claim 1 .

The damping fluid is
comprising a fluid having a surface tension of at least 40 dynes/cm;
25. The system of claim 24 .

The imaging probe is
a distal portion having a diameter of 0.020 inches or less;
The system of claim 1 .

The distal portion of the imaging probe comprises:
having a diameter of 0.016 inches or less;
27. The system of claim 26 .

The imaging probe is
further comprising a sealing element at a distal portion of said elongated shaft;
The system of claim 1 .