JPWO2020118240A5

JPWO2020118240A5 -

Info

Publication number: JPWO2020118240A5
Application number: JP2021531724A
Authority: JP
Publication date: 2022-12-02

Description

特許請求の範囲、ならびに先の本明細書において、すべての移行句、例えば「含む（ｃｏｍｐｒｉｓｉｎｇ）」、「含む（ｉｎｃｌｕｄｉｎｇ）」、「担持する（ｃａｒｒｙｉｎｇ）」、「有する（ｈａｖｉｎｇ）」、「含有する（ｃｏｎｔａｉｎｉｎｇ）」、「伴う（ｉｎｖｏｌｖｉｎｇ）」、「保持する（ｈｏｌｄｉｎｇ）」等は、オープンエンドであり、すなわち、それに限定されるものではないが含む、を意味すると理解されるべきである。移行句「からなる（ｃｏｎｓｉｓｔｉｎｇｏｆ）」および「から本質的になる（ｃｏｎｓｉｓｔｉｎｇｅｓｓｅｎｔｉａｌｌｙｏｆ）」だけは、それぞれ、米国特許庁特許審査便覧、セクション２１１１．０３に記載されている通り、クローズドまたはセミクローズド移行句であるものとする。
本発明は、例えば以下の項目を提供する。
(項目１)
シリカ系送達材料、および
前記シリカ系送達材料中に、前記シリカ系送達材料および抗菌薬の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する抗菌薬
を含む組成物であって、湿気が前記組成物に導入されると、前記抗菌薬の少なくとも一部が前記組成物から放出されるように、前記抗菌薬が前記シリカ系送達材料と会合している、組成物。
(項目２)
シリカ系送達材料、および
前記シリカ系送達材料中に、組成物の重量に対して少なくとも約０．００１ｗｔ％の量で存在する抗菌薬
を含む組成物であって、湿気が前記組成物に導入されると、前記抗菌薬の少なくとも一部が前記組成物から放出されるように、前記抗菌薬が前記シリカ系送達材料と会合している、組成物。
(項目３)
シリカ、および
前記シリカ中に、前記シリカおよび抗菌薬の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する抗菌薬
を含む組成物であって、湿気が前記組成物に導入されると、前記抗菌薬の少なくとも一部が前記組成物から放出されるように、前記抗菌薬が前記シリカと会合している、組成物。
(項目４)
シリカ、および
前記シリカ中に、組成物の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する抗菌薬
を含む組成物であって、湿気が前記組成物に導入されると、前記抗菌薬の少なくとも一部が前記組成物から放出されるように、前記抗菌薬が前記シリカと会合している、組成物。
(項目５)
前記項目のいずれかに記載の組成物、および
分散媒
を含む抗菌複合体であって、前記組成物が、前記分散媒に分散させられており、湿気が前記抗菌複合体に導入されると、前記抗菌薬の少なくとも一部が前記抗菌複合体から放出されるように、前記抗菌薬が前記シリカ系送達材料と会合している、抗菌複合体。
(項目６)
シリカおよび抗菌薬を含む組成物、ならびに
分散媒
を含む抗菌複合体であって、前記抗菌薬が、前記抗菌複合体の全重量に対して少なくとも約０．００１ｗｔ％の量で存在し、
湿気が前記組成物に導入されると、前記抗菌薬の少なくとも一部が前記組成物から放出されるように、前記抗菌薬が前記シリカと会合している、抗菌複合体。
(項目７)
シリカ系送達材料および抗菌薬を含む組成物、ならびに
分散媒
を含む抗菌複合体であって、前記抗菌薬が、前記抗菌複合体の全重量に対して少なくとも約０．００１ｗｔ％の量で存在し、
湿気が前記組成物に導入されると、前記抗菌薬の少なくとも一部が前記組成物から放出されるように、前記抗菌薬が、前記シリカ系送達材料と会合している、抗菌複合体。
(項目８)
固体材料に分散させられた前記項目のいずれかに記載の組成物を含む抗菌複合体であって、湿気が前記抗菌複合体に導入されると、前記抗菌薬の少なくとも一部が前記抗菌複合体から放出されるように、前記抗菌薬が前記シリカ系送達材料と会合している、抗菌複合体。
(項目９)
繊維材料に分散させられた前記項目のいずれかに記載の組成物を含む抗菌複合体であって、湿気が前記抗菌複合体に導入されると、前記抗菌薬の少なくとも一部が前記抗菌複合体から放出されるように、前記抗菌薬が前記シリカ系送達材料と会合している、抗菌複合体。
(項目１０)
分散媒、および
前記項目のいずれかに記載の組成物を含むマトリックス
を含む抗菌複合体であって、前記マトリックスが、前記分散媒中に、前記分散媒および前記マトリックスの全重量に対して少なくとも約０．００１ｗｔ％の量で存在し、湿気が前記抗菌複合体に導入されると、前記抗菌薬の少なくとも一部が前記抗菌複合体から放出されるように、前記抗菌薬が前記シリカ系送達材料と会合している、抗菌複合体。
(項目１１)
抗菌複合体中に、前記抗菌複合体の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する抗菌薬を含む抗菌複合体であって、湿気が前記抗菌複合体に導入されると、前記抗菌薬の少なくとも一部が前記抗菌複合体から放出されるように、前記抗菌薬が前記抗菌複合体の少なくとも一部と会合している、抗菌複合体。
(項目１２)
抗菌複合体中に、前記抗菌複合体の全重量に対して少なくとも約２０ｗｔ％の量で存在する送達材料、および
前記送達材料と会合している抗菌薬
を含む抗菌複合体。
(項目１３)
抗菌複合体中に、前記抗菌複合体の全重量に対して最大約４５ｗｔ％の量で存在する送達材料、および
前記送達材料と会合している抗菌薬
を含む抗菌複合体。
(項目１４)
抗菌薬を含むパッケージング挿入物であって、前記抗菌薬が、前記パッケージング挿入物中に、前記パッケージング挿入物の全重量に対して少なくとも約０．００１ｗｔ％の量で存在し、湿気が前記パッケージング挿入物に導入されると、前記抗菌薬の少なくとも一部が前記パッケージング挿入物から放出されるように、前記抗菌薬が前記パッケージング挿入物の少なくとも一部と会合している、パッケージング挿入物。
(項目１５)
分散媒を含む、前記項目のいずれかに記載の抗菌複合体。
(項目１６)
前記項目のいずれかに記載の抗菌複合体を含むパッケージング挿入物。
(項目１７)
抗菌複合体に統合された、前記項目のいずれかに記載の組成物。
(項目１８)
パッケージング挿入物に統合された、前記項目のいずれかに記載の組成物。
(項目１９)
前記項目のいずれかに記載のパッケージング挿入物を含むパッケージ。
(項目２０)
農産物をさらに含む、前記項目のいずれかに記載のパッケージ。
(項目２１)
フルーツをさらに含む、前記項目のいずれかに記載のパッケージ。
(項目２２)
ベリーをさらに含む、前記項目のいずれかに記載のパッケージ。
(項目２３)
肉をさらに含む、前記項目のいずれかに記載のパッケージ。
(項目２４)
皮製品をさらに含む、前記項目のいずれかに記載のパッケージ。
(項目２５)
前記皮製品が、少なくとも１つの靴を含む、前記項目のいずれかに記載のパッケージ。
(項目２６)
前記パッケージが、前記パッケージング挿入物が恒久的にまたは取り外し可能に固定されているパレット、ボックス、ケース、パネット、またはクラムシェルの１つまたは複数を含む、前記項目のいずれかに記載のパッケージ。
(項目２７)
ベリーのパッケージングに取り外し可能にまたは恒久的に結合されている、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目２８)
ベリーのクラムシェルに取り外し可能にまたは恒久的に結合されている、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目２９)
前記繊維材料が、木材パルプおよび／または木質繊維を含む、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目３０)
前記繊維材料が、木材パルプおよび木質繊維の１つである、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目３１)
前記抗菌複合体が、ポリエチレンフィルムを含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目３２)
前記抗菌複合体が、ポリマー材料を含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目３３)
前記分散媒が、ポリマー材料を含む、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目３４)
前記分散媒が、ポリマー材料である、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目３５)
前記ポリマー材料が、セルロースを含む、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目３６)
前記ポリマー材料が、セルロースである、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目３７)
前記分散媒が、セルロースを含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目３８)
前記分散媒が、セルロースである、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目３９)
前記抗菌複合体が、紙、フィルム、またはプラスチックの１つを含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目４０)
前記抗菌複合体または前記パッケージング挿入物の形状因子が、紙、フィルム、またはプラスチックの１つである、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目４１)
前記パッケージング挿入物の形状因子が、パッドの１つである、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目４２)
前記パッドが、抗菌複合体を含む１つまたは複数の層およびポリエチレンフィルムを含む１つまたは複数の層を含む、項目４１に記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目４３)
前記パッドが、抗菌複合体およびポリエチレンフィルムを含む、項目４１に記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目４４)
吸水性材料、接着性材料、および透水性材料の１つまたは複数をさらに含む、前記項目のいずれかに記載のパッケージング挿入物。
(項目４５)
抗菌複合体、吸水層、接着層、および透水性材料の１つまたは複数をさらに含む、前記項目のいずれかに記載のパッケージング挿入物。
(項目４６)
前記シリカ系送達材料が、吸着性材料である、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目４７)
前記シリカ系送達材料が、多孔性固体である、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目４８)
前記抗菌薬が、２つまたはそれよりも多い抗菌薬の組合せである、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目４９)
前記抗菌薬が、エッセンシャルオイルを含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目５０)
前記抗菌薬が、クローブ油、クローブ抽出物、バニラ抽出物、およびレモングラス油の１つまたは複数を含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目５１)
約２０μｍ～約８０μｍの間の円相当径（ＣＥＤ）の平均粒径および／もしくは約５０Å～約７５Åの間の平均孔径を有する送達材料、ならびに／または
約２０μｍ～約８０μｍの間の円相当径（ＣＥＤ）の平均粒径を有するマトリックス、ならびに／または
約１００ｇ／ｍ ^２～約３００ｇ／ｍ ^２の間の坪量を有する抗菌複合体
を含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目５２)
前記組成物、抗菌複合体、またはパッケージング挿入物が、分散媒およびマトリックスを含み、前記抗菌薬が、前記分散媒中に、前記マトリックスおよび前記分散媒の全重量に対して約０．０１ｗｔ％～約１．５ｗｔ％の間の量で存在し、前記分散媒が、前記組成物、抗菌複合体、またはパッケージング挿入物中に、前記組成物、抗菌複合体、またはパッケージング挿入物の全重量に対して少なくとも約５０ｗｔ％の量で存在する、項目５１に記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目５３)
前記シリカ系送達材料が、約５０～約１５００ｍ ^２／ｇ、約１００～約１５００ｍ ^２／ｇ、約２５０～約１０００ｍ ^２／ｇ、約３００～約１２００ｍ ^２／ｇ、約３５０～約８５０ｍ ^２／ｇ、約４００～約８００ｍ ^２／ｇ、約４００～約６００ｍ ^２／ｇ、約４５０～約６５０ｍ ^２／ｇ、約６００～約８００ｍ ^２／ｇ、または約６２０～約８２０ｍ ^２／ｇの範囲の表面積を有する、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目５４)
前記シリカ系送達材料が、約５Å～約１００Åの間、約２０Å～約１００Åの間、約３０Å～約９０Åの間、約４０Å～約１００Åの間、約４０Å～約８０Åの間、約４０Å～約７０Åの間、約４０Å～約７５Åの間、約４０Å～約６５Åの間、約５０Å～約７５Åの間、約５０Å～約６５Åの間、約５５Å～約６５Åの間、または約５７Å～約６３Åの間の平均孔径を有する、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目５５)
前記シリカ系送達材料が、約０．１ｍＬ／ｇ～約１．５ｍＬ／ｇの間、約０．３ｍＬ／ｇ～約１．３ｍＬ／ｇの間、約０．５ｍＬ／ｇ～約１．５ｍＬ／ｇの間、約０．５ｍＬ／ｇ～約１．３ｍＬ／ｇの間、約０．５ｍＬ／ｇ～約１．０ｍＬ／ｇの間、約０．５ｍＬ／ｇ～約０．９ｍＬ／ｇの間、約０．６ｍＬ／ｇ～約１．０ｍＬ／ｇの間、約０．６ｍＬ／ｇ～約０．９ｍＬ／ｇの間、約０．６ｍＬ／ｇ～約０．８ｍＬ／ｇの間、約０．７ｍＬ／ｇ～約１．０ｍＬ／ｇの間、約０．８ｍＬ／ｇ～約１．０ｍＬ／ｇの間、約０．８ｍＬ／ｇ～約１．５ｍＬ／ｇの間、約０．９ｍＬ／ｇ～約１．５ｍＬ／ｇの間、または約０．９ｍＬ／ｇ～約１．３ｍＬ／ｇの間の内部空隙容量を有する、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目５６)
前記マトリックスが、約５μｍ～約２５０μｍの間、約１０μｍ～約１５０μｍの間、約１０μｍ～約４０μｍの間、約１０μｍ～約５０μｍの間、約２０μｍ～約４０μｍの間、約２５μｍ～約４５μｍの間、約２０μｍ～約５０μｍの間、約２０μｍ～約６０μｍの間、約３０μｍ～約１５０μｍの間、約５０μｍ～約１５０μｍの間、約６０μｍ～約１２０μｍの間、または約３０μｍ～約８０μｍの間、約４０μｍ～約６５μｍの間、約３５μｍ～約７５μｍの間、約５２μｍ～約７５μｍの間、または約１０μｍ～約８０μｍの間の円相当径（ＣＥＤ）の平均粒径を有する、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目５７)
前記抗菌複合体が、約１０ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約１０ｇ／ｍ ^２～約２５ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約３０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約５０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約８０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約１００ｇ／ｍ ^２の間、約２５ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約２５ｇ／ｍ ^２～約１００ｇ／ｍ ^２の間、約５０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約８０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約９０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約２００ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約３００ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約５００ｇ／ｍ ^２の間、約２５０ｇ／ｍ ^２～約７５０ｇ／ｍ ^２の間、約５００ｇ／ｍ ^２～約８００ｇ／ｍ ^２の間、または約７５０ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間の坪量を有する、前記項目のいずれかに記載の抗菌複合体。
(項目５８)
前記分散媒が、約１０ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約１０ｇ／ｍ ^２～約２５ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約３０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約５０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約８０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約１００ｇ／ｍ ^２の間、約２５ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約２５ｇ／ｍ ^２～約１００ｇ／ｍ ^２の間、約５０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約８０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約９０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約２００ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約３００ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約５００ｇ／ｍ ^２の間、約２５０ｇ／ｍ ^２～約７５０ｇ／ｍ ^２の間、約５００ｇ／ｍ ^２～約８００ｇ／ｍ ^２の間、または約７５０ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間の坪量を有する、前記項目のいずれかに記載の抗菌複合体。
(項目５９)
前記シリカ系送達材料が、マクロ多孔性シリカ系材料、メソ多孔性シリカ系材料、および微孔性シリカ系材料、および関連誘導体、ならびにそれらの組合せのうちの少なくとも１つを含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目６０)
前記シリカ系送達材料が、非晶質シリカ、フュームドシリカ、微粒子状シリカ、粉砕石英、微粒子状、フュームド、結晶性および粉砕二酸化ケイ素および関連誘導体、ならびにそれらの組合せのうちの少なくとも１つを含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目６１)
前記シリカ系送達材料が、金属酸化物、半金属酸化物、およびそれらの組合せの１つまたは複数をさらに含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目６２)
前記シリカ系送達材料が、酸化亜鉛、酸化チタン、第１３族または第１４族酸化物、およびそれらの組合せの１つまたは複数をさらに含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目６３)
前記シリカ系送達材料が、酸化アルミニウムをさらに含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目６４)
前記シリカ系送達材料が、酸化亜鉛をさらに含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目６５)
前記シリカ系送達材料が、酸化アルミニウムの一部をさらに含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目６６)
前記抗菌薬が、前記シリカ系送達材料中に、前記シリカ系送達材料および前記抗菌薬の全重量に対して約０．００１ｗｔ％～約２０ｗｔ％の間、約０．０５ｗｔ％～約２０ｗｔ％の間、約０．１ｗｔ％～約２０ｗｔ％の間、約０．５ｗｔ％～約２０ｗｔ％の間、約１ｗｔ％～約２０ｗｔ％の間、約１．５ｗｔ％～約２０ｗｔ％の間、約２ｗｔ％～約２０ｗｔ％の間、約４ｗｔ％～約２０ｗｔ％の間、約５ｗｔ％～約２０ｗｔ％の間、約７ｗｔ％～約２０ｗｔ％の間、約１０ｗｔ％～約２０ｗｔ％の間、約２ｗｔ％～約７ｗｔ％の間、約２ｗｔ％～約１０ｗｔ％の間、約２ｗｔ％～約１５ｗｔ％の間、約４ｗｔ％～約１０ｗｔ％の間、約４ｗｔ％～約１５ｗｔ％の間、または約７ｗｔ％～約１５ｗｔ％の間の量で存在する、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目６７)
前記抗菌薬が、前記シリカ系送達材料中に、前記シリカ系送達材料および前記抗菌薬の全重量に対して約０．００１ｗｔ％～約３ｗｔ％の間、約０．０３ｗｔ％～約０．１ｗｔ％の間、約０．０３ｗｔ％～約０．５ｗｔ％の間、約０．０３ｗｔ％～約１ｗｔ％の間、約０．０３ｗｔ％～約１．５ｗｔ％の間、約０．０３ｗｔ％～約３ｗｔ％の間、約０．０５ｗｔ％～約１．５ｗｔ％の間、約０．０５ｗｔ％～約３ｗｔ％の間、約０．５ｗｔ％～約５ｗｔ％の間、約１ｗｔ％～約５ｗｔ％の間、約２ｗｔ％～約１０ｗｔ％の間の量で存在する、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目６８)
前記マトリックスが、前記分散媒中に、前記分散媒および前記マトリックスの全重量に対して約１ｗｔ％～約８０ｗｔ％の間、約５ｗｔ％～約２０ｗｔ％の間、約１０ｗｔ％～約２０ｗｔ％の間、約１０ｗｔ％～約５０ｗｔ％の間、約１０ｗｔ％～約６０ｗｔ％の間、約１５ｗｔ％～約５０ｗｔ％の間、約１５ｗｔ％～約６０ｗｔ％の間、約２０ｗｔ％～約４０ｗｔ％の間、約２０ｗｔ％～約５０ｗｔ％の間、約２０ｗｔ％～約６０ｗｔ％の間、約２５ｗｔ％～約４０ｗｔ％の間、約３０ｗｔ％～約３７ｗｔ％の間、約３０ｗｔ％～約４０ｗｔ％の間、約３０ｗｔ％～約５０ｗｔ％の間、約３０ｗｔ％～約６０ｗｔ％の間、約３１ｗｔ％～約３７ｗｔ％の間、約３２ｗｔ％～約３７ｗｔ％の間、約４０ｗｔ％～約６０ｗｔ％の間、または約４０ｗｔ％～約７５ｗｔ％の間の量で存在する、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目６９)
前記分散媒が、前記抗菌複合体中に、前記分散媒および前記マトリックスの全重量に対して少なくとも約５０ｗｔ％、少なくとも約５５ｗｔ％、少なくとも約６０ｗｔ％、少なくとも約６２ｗｔ％、少なくとも約６５ｗｔ％、少なくとも約７０ｗｔ％、少なくとも約７５ｗｔ％、少なくとも約８０ｗｔ％、少なくとも約８５ｗｔ％、少なくとも約９０ｗｔ％、少なくとも約９５ｗｔ％、または少なくとも約９９ｗｔ％の量で存在する、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目７０)
前記分散媒が、前記抗菌複合体中に、前記分散媒および前記マトリックスの全重量に対して約５０ｗｔ％～約９９ｗｔ％の間、約５５ｗｔ％～約９９ｗｔ％の間、約６０ｗｔ％～約９９ｗｔ％の間、約６２ｗｔ％～約９９ｗｔ％の間、約６５ｗｔ％～約９９ｗｔ％の間、約７０ｗｔ％～約９９ｗｔ％の間、約７５ｗｔ％～約９９ｗｔ％の間、約５０ｗｔ％～約７５ｗｔ％の間、約５５ｗｔ％～約７５ｗｔ％の間、約６０ｗｔ％～約７５ｗｔ％の間、または約６０ｗｔ％～約７０ｗｔ％の間の量で存在する、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目７１)
前記送達材料が、前記抗菌複合体中に、前記抗菌複合体の全重量に対して約１ｗｔ％～約４５ｗｔ％の間、約１ｗｔ％～約４０ｗｔ％の間、約５ｗｔ％～約４５ｗｔ％の間、約５ｗｔ％～約４０ｗｔ％の間、約１０ｗｔ％～約４５ｗｔ％の間、約１０ｗｔ％～約４０ｗｔ％の間、約１５ｗｔ％～約４５ｗｔ％の間、約１５ｗｔ％～約４０ｗｔ％の間、約２０ｗｔ％～約４５ｗｔ％の間、約２０ｗｔ％～約４０ｗｔ％の間、約２５ｗｔ％～約４５ｗｔ％の間、約２５ｗｔ％～約４０ｗｔ％の間、約３０ｗｔ％～約４４ｗｔ％の間、約３０ｗｔ％～約４０ｗｔ％の間、約３５ｗｔ％～約４５ｗｔ％の間、または約３５ｗｔ％～約４０ｗｔ％の間の量で存在する、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目７２)
前記送達材料が、前記抗菌複合体中に、前記マトリックスおよび前記分散媒の全重量に対して約１ｗｔ％～約４５ｗｔ％の間、約１ｗｔ％～約４０ｗｔ％の間、約５ｗｔ％～約４５ｗｔ％の間、約５ｗｔ％～約４０ｗｔ％の間、約１０ｗｔ％～約４５ｗｔ％の間、約１０ｗｔ％～約４０ｗｔ％の間、約１５ｗｔ％～約４５ｗｔ％の間、約１５ｗｔ％～約４０ｗｔ％の間、約２０ｗｔ％～約４５ｗｔ％の間、約２０ｗｔ％～約４０ｗｔ％の間、約２５ｗｔ％～約４５ｗｔ％の間、約２５ｗｔ％～約４０ｗｔ％の間、約３０ｗｔ％～約４４ｗｔ％の間、約３０ｗｔ％～約４０ｗｔ％の間、約３５ｗｔ％～約４５ｗｔ％の間、または約３５ｗｔ％～約４０ｗｔ％の間の量で存在する、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目７３)
前記抗菌薬が、前記分散媒中に、前記分散媒および前記マトリックスの全重量に対して約０．００１ｗｔ％～約０．００５ｗｔ％の間、約０．００１ｗｔ％～約０．０１ｗｔ％の間、約０．００１ｗｔ％～約０．０５ｗｔ％の間、約０．００１ｗｔ％～約０．１ｗｔ％の間、約０．００１ｗｔ％～約０．５ｗｔ％の間、約０．００１ｗｔ％～約１ｗｔ％の間、約０．００１ｗｔ％～約２ｗｔ％の間、約０．００１ｗｔ％～約５ｗｔ％の間、約０．００１ｗｔ％～約１０ｗｔ％の間、約０．０１ｗｔ％～約０．０５ｗｔ％の間、約０．０１ｗｔ％～約０．１ｗｔ％の間、約０．０１ｗｔ％～約０．１５ｗｔ％の間、約０．０１ｗｔ％～約０．２ｗｔ％の間、約０．０１ｗｔ％～約０．５ｗｔ％の間、約０．０１ｗｔ％～約１ｗｔ％の間、約０．０１ｗｔ％～約２ｗｔ％の間、約０．０１ｗｔ％～約５ｗｔ％の間、約０．０１ｗｔ％～約１０ｗｔ％の間、約０．０５ｗｔ％～約０．１ｗｔ％の間、約０．０５ｗｔ％～約０．５ｗｔ％の間、約０．０５ｗｔ％～約１ｗｔ％の間、約０．０５ｗｔ％～約２ｗｔ％の間、約０．０５ｗｔ％～約５ｗｔ％の間、約０．０５ｗｔ％～約１０ｗｔ％の間、約０．１ｗｔ％～約０．５ｗｔ％の間、約０．１ｗｔ％～約１ｗｔ％の間、約０．１ｗｔ％～約２ｗｔ％の間、約０．１ｗｔ％～約５ｗｔ％の間、約０．１ｗｔ％～約１０ｗｔ％の間、約０．５ｗｔ％～約１ｗｔ％の間、約０．５ｗｔ％～約２ｗｔ％の間、約０．５ｗｔ％～約５ｗｔ％の間、約０．５ｗｔ％～約１０ｗｔ％の間、約１ｗｔ％～約５ｗｔ％の間、約１ｗｔ％～約１０ｗｔ％の間、約１．５ｗｔ％～約１０ｗｔ％の間、約２ｗｔ％～約１０ｗｔ％の間、約４ｗｔ％～約１０ｗｔ％の間、約５ｗｔ％～約１０ｗｔ％の間、約７ｗｔ％～約１０ｗｔ％の間、約２ｗｔ％～約７ｗｔ％の間、約２ｗｔ％～約１０ｗｔ％の間、または約４ｗｔ％～約１０ｗｔ％の間の量で存在する、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目７４)
前記抗菌複合体が、湿潤性抗菌複合体および吸水性抗菌複合体のうちの少なくとも１つである、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目７５)
前記分散媒が、湿潤性分散媒および吸水性分散媒のうちの少なくとも１つである、前記項目のいずれかに記載の抗菌複合体またはパッケージング挿入物。
(項目７６)
前記抗菌薬が、テルペン、テルペノイド、フェノール、フェノール化合物、チモール、クルクミン、カルバクロール、ローリエ葉油、レモングラス油、ペパーミント油、スペアミント油、ウィンターグリーン油、アカシア油、ユーカリプトール、リモネン、オイゲノール、メントール、ファルネソール、カルボン、ヘキサナール、タイム油、ディル油、オレガノ油、ニーム油、オレンジピール油、レモンピール油、ローズマリー油、クミンシード抽出物、タイム油、ヘキサナール、チモール、オイゲノール、および酢酸オイゲニル、クローブ油、クローブ抽出物、バニラ油、バニラ抽出物、シトロネラル、およびバニリン、クルクミン、サリチル酸メチル、およびジャスモン酸メチルまたはその誘導体のうちの少なくとも１つを含む、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目７７)
前記抗菌薬が、テルペン、テルペノイド、フェノール、フェノール化合物、チモール、クルクミン、カルバクロール、ローリエ葉油、レモングラス油、ペパーミント油、スペアミント油、ウィンターグリーン油、アカシア油、ユーカリプトール、リモネン、オイゲノール、メントール、ファルネソール、カルボン、ヘキサナール、タイム油、ディル油、オレガノ油、ニーム油、オレンジピール油、レモンピール油、ローズマリー油、クミンシード抽出物、タイム油、ヘキサナール、および酢酸オイゲニル、クローブ油、クローブ抽出物、バニラ油、バニラ抽出物、シトロネラル、およびバニリン、サリチル酸メチル、ジャスモン酸メチルまたはその誘導体、およびそれらの組合せからなる群から選択される、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物。
(項目７８)
放出された抗菌薬が、病原体または害虫の作用または有害効果を抑制するように、前記項目のいずれかに記載の組成物、抗菌複合体、またはパッケージング挿入物から前記抗菌薬を湿気活性化によって放出させるステップを含む方法。
(項目７９)
水蒸気からの水が、前記組成物、抗菌複合体、またはパッケージング挿入物上またはそれらの中で凝縮するように、前記湿気活性化が、前記組成物、抗菌複合体、またはパッケージング挿入物の水蒸気への曝露を含む、項目７８に記載の方法。
(項目８０)
前記組成物、抗菌複合体、またはパッケージング挿入物を、液体水に直接的に曝露するステップをさらに含む、項目７８～７９のいずれか一項に記載の方法。
(項目８１)
抗菌薬が組成物から放出されるように、シリカ系送達材料中に保存された抗菌薬を含む組成物を湿気に曝露するステップを含む方法。
(項目８２)
前記抗菌薬が、前記組成物中に、前記シリカ系送達材料および前記抗菌薬の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する、項目８１に記載の方法。
(項目８３)
前記抗菌薬が、前記組成物中に、前記組成物の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する、項目８１に記載の方法。
(項目８４)
抗菌薬が抗菌複合体から放出されるように、前記抗菌薬を含む前記抗菌複合体を湿気に曝露するステップを含む方法であって、前記抗菌複合体が、
分散媒、および
前記分散媒に分散したシリカ系送達材料
を含み、前記抗菌薬が、放出前に前記シリカ系送達材料中に保存されている、方法。
(項目８５)
前記抗菌薬が、前記抗菌複合体中に、前記シリカ系送達材料および前記抗菌薬の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する、項目８４に記載の方法。
(項目８６)
前記抗菌薬が、前記抗菌複合体中に、前記抗菌複合体の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する、項目８４に記載の方法。
(項目８７)
抗菌薬が抗菌複合体から放出されるように、前記抗菌薬を含む前記抗菌複合体を湿気に曝露するステップを含む方法であって、前記抗菌複合体が、
固体材料、および
分散媒に分散したシリカ
を含み、前記抗菌薬が、放出前に前記シリカ中に保存されている、方法。
(項目８８)
前記抗菌薬が、前記抗菌複合体中に、前記シリカ材料および前記抗菌薬の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する、項目８７に記載の方法。
(項目８９)
前記抗菌薬が、前記抗菌複合体中に、前記抗菌複合体の全重量に対して少なくとも約０．００１ｗｔ％の量で存在する、項目８７に記載の方法。
(項目９０)
抗菌薬が組成物から放出されるように、農産物および前記抗菌薬を含む組成物を含むパッケージを湿気に曝露するステップを含む方法。
(項目９１)
前記湿気が、前記農産物によって排出される、前記方法項目のいずれかに記載の方法。
(項目９２)
前記農産物の微生物および／または真菌活性を低減するステップをさらに含む、前記方法項目のいずれかに記載の方法。
(項目９３)
前記パッケージが、前記抗菌薬を含むパッケージング挿入物を含み、前記曝露ステップが、前記抗菌薬が前記パッケージング挿入物から放出されるように、前記パッケージング挿入物を前記湿気に曝露することを含む、前記方法項目のいずれかに記載の方法。
(項目９４)
前記組成物が、シリカを含み、前記抗菌薬が、前記シリカに吸着されている、前記方法項目のいずれかに記載の方法。
(項目９５)
前記組成物が、シリカ系送達材料を含み、前記抗菌薬が、放出前に、前記シリカ系送達材料中に保存されている、前記方法項目のいずれかに記載の方法。
(項目９６)
前記組成物および／または前記抗菌複合体が、分散媒をさらに含む、前記方法項目のいずれかに記載の方法。
(項目９７)
前記分散媒が、ポリマー材料を含む、項目９６に記載の方法。
(項目９８)
前記ポリマー材料が、セルロースを含む、項目９７に記載の方法。
(項目９９)
前記分散媒が、約１０ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約１０ｇ／ｍ ^２～約２５ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約３０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約５０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約８０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約１００ｇ／ｍ ^２の間、約２５ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約２５ｇ／ｍ ^２～約１００ｇ／ｍ ^２の間、約５０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約８０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約９０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約２００ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約３００ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約２００ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約５００ｇ／ｍ ^２の間、約２５０ｇ／ｍ ^２～約７５０ｇ／ｍ ^２の間、約５００ｇ／ｍ ^２～約８００ｇ／ｍ ^２の間、または約７５０ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間の坪量を有する、項目９６～９８のいずれかに記載の方法。
(項目１００)
前記組成物および／または前記抗菌複合体が、マトリックスをさらに含む、前記方法項目のいずれかに記載の方法。
(項目１０１)
前記マトリックスが、前記分散媒中に、前記分散媒および前記マトリックスの全重量に対して約１ｗｔ％～約８０ｗｔ％の間、約５ｗｔ％～約２０ｗｔ％の間、約１０ｗｔ％～約２０ｗｔ％の間、約１０ｗｔ％～約５０ｗｔ％の間、約１０ｗｔ％～約６０ｗｔ％の間、約１５ｗｔ％～約５０ｗｔ％の間、約１５ｗｔ％～約６０ｗｔ％の間、約２０ｗｔ％～約４０ｗｔ％の間、約２０ｗｔ％～約５０ｗｔ％の間、約２０ｗｔ％～約６０ｗｔ％の間、約２５ｗｔ％～約４０ｗｔ％の間、約３０ｗｔ％～約３７ｗｔ％の間、約３０ｗｔ％～約４０ｗｔ％の間、約３０ｗｔ％～約５０ｗｔ％の間、約３０ｗｔ％～約６０ｗｔ％の間、約３１ｗｔ％～約３７ｗｔ％の間、約３２ｗｔ％～約３７ｗｔ％の間、約４０ｗｔ％～約６０ｗｔ％の間、または約４０ｗｔ％～約７５ｗｔ％の間の量で存在する、項目１００に記載の方法。
(項目１０２)
前記マトリックスが、約５μｍ～約２５０μｍの間、約１０μｍ～約１５０μｍの間、約１０μｍ～約４０μｍの間、約１０μｍ～約５０μｍの間、約２０μｍ～約４０μｍの間、約２５μｍ～約４５μｍの間、約２０μｍ～約５０μｍの間、約２０μｍ～約６０μｍの間、約３０μｍ～約１５０μｍの間、約５０μｍ～約１５０μｍの間、約６０μｍ～約１２０μｍの間、または約３０μｍ～約８０μｍの間、約４０μｍ～約６５μｍの間、約３５μｍ～約７５μｍの間、約５２μｍ～約７５μｍの間、または約１０μｍ～約８０μｍの間の円相当径（ＣＥＤ）の平均粒径を有する、前記方法項目のいずれかに記載の方法。
(項目１０３)
前記抗菌薬が、前記分散媒中に、前記分散媒および前記マトリックスの全重量に対して約０．００１ｗｔ％～約０．００５ｗｔ％の間、約０．００１ｗｔ％～約０．０１ｗｔ％の間、約０．００１ｗｔ％～約０．０５ｗｔ％の間、約０．００１ｗｔ％～約０．１ｗｔ％の間、約０．００１ｗｔ％～約０．５ｗｔ％の間、約０．００１ｗｔ％～約１ｗｔ％の間、約０．００１ｗｔ％～約２ｗｔ％の間、約０．００１ｗｔ％～約５ｗｔ％の間、約０．００１ｗｔ％～約１０ｗｔ％の間、約０．０１ｗｔ％～約０．０５ｗｔ％の間、約０．０１ｗｔ％～約０．１ｗｔ％の間、約０．０１ｗｔ％～約０．５ｗｔ％の間、約０．０１ｗｔ％～約１ｗｔ％の間、約０．０１ｗｔ％～約２ｗｔ％の間、約０．０１ｗｔ％～約５ｗｔ％の間、約０．０１ｗｔ％～約１０ｗｔ％の間、約０．０５ｗｔ％～約０．１ｗｔ％の間、約０．０５ｗｔ％～約０．５ｗｔ％の間、約０．０５ｗｔ％～約１ｗｔ％の間、約０．０５ｗｔ％～約２ｗｔ％の間、約０．０５ｗｔ％～約５ｗｔ％の間、約０．０５ｗｔ％～約１０ｗｔ％の間、約０．１ｗｔ％～約０．５ｗｔ％の間、約０．１ｗｔ％～約１ｗｔ％の間、約０．１ｗｔ％～約２ｗｔ％の間、約０．１ｗｔ％～約５ｗｔ％の間、約０．１ｗｔ％～約１０ｗｔ％の間、約０．５ｗｔ％～約１ｗｔ％の間、約０．５ｗｔ％～約２ｗｔ％の間、約０．５ｗｔ％～約５ｗｔ％の間、約０．５ｗｔ％～約１０ｗｔ％の間、約１ｗｔ％～約５ｗｔ％の間、約１ｗｔ％～約１０ｗｔ％の間、約１．５ｗｔ％～約１０ｗｔ％の間、約２ｗｔ％～約１０ｗｔ％の間、約４ｗｔ％～約１０ｗｔ％の間、約５ｗｔ％～約１０ｗｔ％の間、約７ｗｔ％～約１０ｗｔ％の間、約２ｗｔ％～約７ｗｔ％の間、約２ｗｔ％～約１０ｗｔ％の間、または約４ｗｔ％～約１０ｗｔ％の間の量で存在する、項目９６～１０２のいずれかに記載の方法。
(項目１０４)
前記分散媒が、湿潤性分散媒および吸水性分散媒のうちの少なくとも１つである、項目９６～１０４のいずれか一項に記載の方法。
(項目１０５)
前記組成物および／または前記抗菌複合体が、パッケージング挿入物に統合されている、前記方法項目のいずれか一項に記載の方法。
(項目１０６)
前記パッケージング挿入物が、吸水層、接着層、および透水性材料の１つまたは複数をさらに含む、前記方法項目のいずれか一項に記載の方法。
(項目１０７)
前記組成物および／または前記抗菌複合体が、パッケージと会合している、前記方法項目のいずれか一項に記載の方法。
(項目１０８)
前記パッケージが、パレット、ボックス、ケース、パネット、またはクラムシェルの１つまたは複数を含む、前記方法項目のいずれか一項に記載の方法。
(項目１０９)
前記組成物および／または前記抗菌複合体が、ポリエチレンフィルムを含む、前記方法項目のいずれか一項に記載の方法。
(項目１１０)
前記組成物および／または前記抗菌複合体が、ポリマー材料を含む、前記方法項目のいずれか一項に記載の方法。
(項目１１１)
前記ポリマー材料が、セルロースを含む、項目１１０に記載の方法。
(項目１１２)
前記組成物および／または前記抗菌複合体が、紙、フィルム、またはプラスチックの１つを含む、前記方法項目のいずれか一項に記載の方法。
(項目１１３)
前記組成物および／または前記抗菌複合体の形状因子が、紙、フィルム、またはプラスチックの１つである、前記方法項目のいずれか一項に記載の方法。
(項目１１４)
前記組成物および／または前記抗菌複合体が、吸水性材料、接着性材料、および透水性材料の１つまたは複数をさらに含む、前記方法項目のいずれか一項に記載の方法。
(項目１１５)
前記シリカ系送達材料が、吸着性材料である、前記方法項目のいずれか一項に記載の方法。
(項目１１６)
前記シリカ系送達材料が、多孔性固体である、前記方法項目のいずれか一項に記載の方法。
(項目１１７)
前記シリカ系送達材料が、約５０～約１５００ｍ ^２／ｇ、約１００～約１５００ｍ ^２／ｇ、約２５０～約１０００ｍ ^２／ｇ、約３００～約１２００ｍ ^２／ｇ、約３５０～約８５０ｍ ^２／ｇ、約４００～約８００ｍ ^２／ｇ、約４００～約６００ｍ ^２／ｇ、約４５０～約６５０ｍ ^２／ｇ、約６００～約８００ｍ ^２／ｇ、または約６２０～約８２０ｍ ^２／ｇの範囲の表面積を有する、前記方法項目のいずれか一項に記載の方法。
(項目１１８)
前記シリカ系送達材料が、約２０Å～約１００Åの間の平均孔径を有する、前記方法項目のいずれか一項に記載の方法。
(項目１１９)
前記シリカ系送達材料が、約０．１ｍＬ／ｇ～約１．５ｍＬ／ｇの間、約０．３ｍＬ／ｇ～約１．３ｍＬ／ｇの間、約０．５ｍＬ／ｇ～約１．５ｍＬ／ｇの間、約０．５ｍＬ／ｇ～約１．３ｍＬ／ｇの間、約０．５ｍＬ／ｇ～約１．０ｍＬ／ｇの間、約０．５ｍＬ／ｇ～約０．９ｍＬ／ｇの間、約０．６ｍＬ／ｇ～約１．０ｍＬ／ｇの間、約０．６ｍＬ／ｇ～約０．９ｍＬ／ｇの間、約０．６ｍＬ／ｇ～約０．８ｍＬ／ｇの間、約０．７ｍＬ／ｇ～約１．０ｍＬ／ｇの間、約０．８ｍＬ／ｇ～約１．０ｍＬ／ｇの間、約０．８ｍＬ／ｇ～約１．５ｍＬ／ｇの間、約０．９ｍＬ／ｇ～約１．５ｍＬ／ｇの間、または約０．９ｍＬ／ｇ～約１．３ｍＬ／ｇの間の内部空隙容量を有する、前記方法項目のいずれか一項に記載の方法。
(項目１２０)
前記シリカ系送達材料が、マクロ多孔性シリカ系材料、メソ多孔性シリカ系材料、および微孔性シリカ系材料、および関連誘導体、ならびにそれらの組合せのうちの少なくとも１つを含む、前記方法項目のいずれか一項に記載の方法。
(項目１２１)
前記シリカ系送達材料が、非晶質シリカ、フュームドシリカ、微粒子状シリカ、粉砕石英、微粒子状、フュームド、結晶性および粉砕二酸化ケイ素および関連誘導体、ならびにそれらの組合せのうちの少なくとも１つを含む、前記方法項目のいずれか一項に記載の方法。
(項目１２２)
前記シリカ系送達材料が、金属酸化物、半金属酸化物、およびそれらの組合せの１つまたは複数をさらに含む、前記方法項目のいずれか一項に記載の方法。
(項目１２３)
前記シリカ系送達材料が、酸化亜鉛、酸化チタン、第１３族または第１４族酸化物、およびそれらの組合せの１つまたは複数をさらに含む、前記方法項目のいずれか一項に記載の方法。
(項目１２４)
前記シリカ系送達材料が、酸化アルミニウムをさらに含む、前記方法項目のいずれか一項に記載の方法。
(項目１２５)
前記シリカ系送達材料が、酸化亜鉛をさらに含む、前記方法項目のいずれか一項に記載の方法。
(項目１２６)
前記シリカ系送達材料が、酸化アルミニウムの一部をさらに含む、前記方法項目のいずれか一項に記載の方法。
(項目１２７)
前記抗菌薬が、前記シリカ系送達材料中に、前記シリカ系送達材料および前記抗菌薬の全重量に対して約０．００１ｗｔ％～約２０ｗｔ％の間、約０．０５ｗｔ％～約２０ｗｔ％の間、約０．１ｗｔ％～約２０ｗｔ％の間、約０．５ｗｔ％～約２０ｗｔ％の間、約１ｗｔ％～約２０ｗｔ％の間、約１．５ｗｔ％～約２０ｗｔ％の間、約２ｗｔ％～約２０ｗｔ％の間、約４ｗｔ％～約２０ｗｔ％の間、約５ｗｔ％～約２０ｗｔ％の間、約７ｗｔ％～約２０ｗｔ％の間、約１０ｗｔ％～約２０ｗｔ％の間、約２ｗｔ％～約７ｗｔ％の間、約２ｗｔ％～約１０ｗｔ％の間、約２ｗｔ％～約１５ｗｔ％の間、約４ｗｔ％～約１０ｗｔ％の間、約４ｗｔ％～約１５ｗｔ％の間、または約７ｗｔ％～約１５ｗｔ％の間の量で存在する、前記方法項目のいずれか一項に記載の方法。
(項目１２８)
前記抗菌薬が、２つまたはそれよりも多い抗菌薬の組合せである、前記方法項目のいずれか一項に記載の方法。
(項目１２９)
前記抗菌薬が、エッセンシャルオイルを含む、前記方法項目のいずれか一項に記載の方法。
(項目１３０)
前記抗菌薬が、クローブ油、クローブ抽出物、バニラ抽出物、およびレモングラス油の１つまたは複数を含む、前記方法項目のいずれか一項に記載の方法。
(項目１３１)
前記抗菌複合体が、湿潤性抗菌複合体および吸水性抗菌複合体のうちの少なくとも１つである、前記方法項目のいずれか一項に記載の方法。
(項目１３２)
前記抗菌薬が、テルペン、テルペノイド、フェノール、フェノール化合物、チモール、クルクミン、カルバクロール、ローリエ葉油、レモングラス油、ペパーミント油、スペアミント油、ウィンターグリーン油、アカシア油、ユーカリプトール、リモネン、オイゲノール、メントール、ファルネソール、カルボン、ヘキサナール、タイム油、ディル油、オレガノ油、ニーム油、オレンジピール油、レモンピール油、ローズマリー油、クミンシード抽出物、タイム油、ヘキサナール、チモール、オイゲノール、および酢酸オイゲニル、クローブ油、クローブ抽出物、バニラ油、バニラ抽出物、シトロネラル、およびバニリン、クルクミン、サリチル酸メチル、ジャスモン酸メチルまたはその誘導体のうちの少なくとも１つを含む、前記方法項目のいずれか一項に記載の方法。
(項目１３３)
前記抗菌薬が、テルペン、テルペノイド、フェノール、フェノール化合物、チモール、クルクミン、カルバクロール、ローリエ葉油、レモングラス油、ペパーミント油、スペアミント油、ウィンターグリーン油、アカシア油、ユーカリプトール、リモネン、オイゲノール、メントール、ファルネソール、カルボン、ヘキサナール、タイム油、ディル油、オレガノ油、ニーム油、オレンジピール油、レモンピール油、ローズマリー油、クミンシード抽出物、タイム油、ヘキサナール、および酢酸オイゲニル、クローブ油、クローブ抽出物、バニラ油、バニラ抽出物、シトロネラル、およびバニリン、サリチル酸メチル、ジャスモン酸メチルまたはその誘導体、およびそれらの組合せからなる群から選択される、前記方法項目のいずれか一項に記載の方法。
(項目１３４)
前記組成物および／または前記抗菌複合体が、約１０ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約１０ｇ／ｍ ^２～約２５ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約３０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約５０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約８０ｇ／ｍ ^２の間、約１５ｇ／ｍ ^２～約１００ｇ／ｍ ^２の間、約２５ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間、約２５ｇ／ｍ ^２～約１００ｇ／ｍ ^２の間、約５０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約８０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約９０ｇ／ｍ ^２～約１５０ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約２００ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約３００ｇ／ｍ ^２の間、約１００ｇ／ｍ ^２～約５００ｇ／ｍ ^２の間、約２５０ｇ／ｍ ^２～約７５０ｇ／ｍ ^２の間、約５００ｇ／ｍ ^２～約８００ｇ／ｍ ^２の間、または約７５０ｇ／ｍ ^２～約１３００ｇ／ｍ ^２の間の坪量を有する、前記方法項目のいずれか一項に記載の方法。 In the claims, as well as hereinbefore, all transitional phrases such as "comprising", "including", "carrying", "having", "containing""Containing","involving","holding", etc. should be understood to mean open ended, i.e. including but not limited to. Only the transitional phrases "consisting of" and "consisting essentially of" are defined as closed or semi-closed, respectively, as set forth in the United States Patent Office Manual of Patent Examining, Section 2111.03. Shall be a transitional clause.
The present invention provides, for example, the following items.
(Item 1)
a silica-based delivery material, and
an antimicrobial agent present in said silica-based delivery material in an amount of at least about 0.001 wt% based on the total weight of said silica-based delivery material and antimicrobial agent
wherein the antimicrobial agent is associated with the silica-based delivery material such that at least a portion of the antimicrobial agent is released from the composition when moisture is introduced into the composition There is a composition.
(Item 2)
a silica-based delivery material, and
an antimicrobial agent present in said silica-based delivery material in an amount of at least about 0.001 wt% by weight of the composition;
wherein the antimicrobial agent is associated with the silica-based delivery material such that at least a portion of the antimicrobial agent is released from the composition when moisture is introduced into the composition There is a composition.
(Item 3)
silica, and
an antimicrobial agent present in said silica in an amount of at least about 0.001 wt% based on the total weight of said silica and antimicrobial agent
wherein said antimicrobial agent is associated with said silica such that at least a portion of said antimicrobial agent is released from said composition when moisture is introduced into said composition thing.
(Item 4)
silica, and
an antimicrobial agent present in said silica in an amount of at least about 0.001 wt%, based on the total weight of the composition;
wherein said antimicrobial agent is associated with said silica such that at least a portion of said antimicrobial agent is released from said composition when moisture is introduced into said composition thing.
(Item 5)
A composition according to any of the preceding items, and
dispersion medium
wherein the composition is dispersed in the dispersion medium and at least a portion of the antimicrobial agent is released from the antimicrobial complex when moisture is introduced into the antimicrobial complex An antimicrobial composite, wherein said antimicrobial agent is associated with said silica-based delivery material, as described above.
(Item 6)
A composition comprising silica and an antimicrobial agent, and
dispersion medium
wherein the antimicrobial agent is present in an amount of at least about 0.001 wt%, based on the total weight of the antimicrobial complex,
An antimicrobial composite, wherein said antimicrobial agent is associated with said silica such that at least a portion of said antimicrobial agent is released from said composition when moisture is introduced into said composition.
(Item 7)
A composition comprising a silica-based delivery material and an antimicrobial agent, and
dispersion medium
wherein the antimicrobial agent is present in an amount of at least about 0.001 wt%, based on the total weight of the antimicrobial complex,
An antimicrobial composite, wherein the antimicrobial agent is associated with the silica-based delivery material such that when moisture is introduced into the composition, at least a portion of the antimicrobial agent is released from the composition.
(Item 8)
An antimicrobial composite comprising a composition according to any of the preceding items dispersed in a solid material, wherein when moisture is introduced into said antimicrobial composite, at least a portion of said antimicrobial agent is absorbed into said antimicrobial composite. wherein said antimicrobial agent is associated with said silica-based delivery material such that it is released from said antimicrobial composite.
(Item 9)
An antimicrobial composite comprising a composition according to any of the preceding items dispersed in a textile material, wherein when moisture is introduced into said antimicrobial composite, at least a portion of said antimicrobial agent is absorbed into said antimicrobial composite. wherein said antimicrobial agent is associated with said silica-based delivery material such that it is released from said antimicrobial composite.
(Item 10)
a dispersion medium, and
A matrix comprising the composition according to any of the preceding items
wherein the matrix is present in the dispersion medium in an amount of at least about 0.001 wt% based on the total weight of the dispersion medium and the matrix, and moisture is present in the antimicrobial composite An antimicrobial composite, wherein the antimicrobial agent is associated with the silica-based delivery material such that, upon introduction, at least a portion of the antimicrobial agent is released from the antimicrobial composite.
(Item 11)
An antimicrobial composite comprising an antimicrobial agent present in the antimicrobial composite in an amount of at least about 0.001 wt% relative to the total weight of the antimicrobial composite, wherein when moisture is introduced into the antimicrobial composite, An antimicrobial complex, wherein said antimicrobial agent is associated with at least a portion of said antimicrobial complex such that at least a portion of said antimicrobial agent is released from said antimicrobial complex.
(Item 12)
a delivery material present in the antimicrobial composite in an amount of at least about 20 wt% relative to the total weight of said antimicrobial composite; and
an antimicrobial agent associated with the delivery material
An antibacterial complex containing.
(Item 13)
a delivery material present in the antimicrobial composite in an amount of up to about 45 wt% relative to the total weight of said antimicrobial composite; and
an antimicrobial agent associated with the delivery material
An antibacterial complex containing.
(Item 14)
A packaging insert comprising an antimicrobial agent, wherein the antimicrobial agent is present in the packaging insert in an amount of at least about 0.001 wt% relative to the total weight of the packaging insert, and wherein moisture is the antimicrobial agent is associated with at least a portion of the packaging insert such that when introduced into the packaging insert, at least a portion of the antimicrobial agent is released from the packaging insert; packaging insert.
(Item 15)
An antimicrobial composite according to any of the preceding items, comprising a dispersion medium.
(Item 16)
A packaging insert comprising an antimicrobial complex according to any of the preceding items.
(Item 17)
A composition according to any of the preceding items incorporated into an antimicrobial complex.
(Item 18)
A composition according to any of the preceding items incorporated into a packaging insert.
(Item 19)
A package comprising a packaging insert according to any of the preceding items.
(Item 20)
A package according to any of the preceding items, further comprising produce.
(Item 21)
A package according to any of the preceding items, further comprising fruit.
(Item 22)
A package according to any of the preceding items, further comprising berries.
(Item 23)
A package according to any of the preceding items, further comprising meat.
(Item 24)
A package according to any of the preceding items, further comprising a leather product.
(Item 25)
A package according to any of the preceding items, wherein the leather article comprises at least one shoe.
(Item 26)
A package according to any of the preceding items, wherein the package comprises one or more of a pallet, box, case, punnet, or clamshell to which the packaging insert is permanently or removably secured.
(Item 27)
An antimicrobial composite or packaging insert according to any of the preceding items removably or permanently associated with berry packaging.
(Item 28)
An antimicrobial composite or packaging insert according to any of the preceding items removably or permanently attached to the clamshell of the berry.
(Item 29)
An antimicrobial composite or packaging insert according to any of the preceding items, wherein the fibrous material comprises wood pulp and/or wood fibres.
(Item 30)
An antimicrobial composite or packaging insert according to any of the preceding items, wherein the fibrous material is one of wood pulp and wood fibres.
(Item 31)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the antimicrobial composite comprises a polyethylene film.
(Item 32)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the antimicrobial composite comprises a polymeric material.
(Item 33)
An antimicrobial composite or packaging insert according to any of the preceding items, wherein the carrier medium comprises a polymeric material.
(Item 34)
An antimicrobial composite or packaging insert according to any of the preceding items, wherein the carrier medium is a polymeric material.
(Item 35)
An antimicrobial composite or packaging insert according to any of the preceding items, wherein the polymeric material comprises cellulose.
(Item 36)
An antimicrobial composite or packaging insert according to any of the preceding items, wherein the polymeric material is cellulose.
(Item 37)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the dispersion medium comprises cellulose.
(Item 38)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the dispersion medium is cellulose.
(Item 39)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the antimicrobial composite comprises one of paper, film, or plastic.
(Item 40)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the form factor of said antimicrobial composite or said packaging insert is one of paper, film, or plastic.
(Item 41)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the form factor of the packaging insert is one of a pad.
(Item 42)
42. The composition, antimicrobial composite, or packaging insert of item 41, wherein said pad comprises one or more layers comprising an antimicrobial composite and one or more layers comprising a polyethylene film.
(Item 43)
42. The composition, antimicrobial composite, or packaging insert of item 41, wherein said pad comprises an antimicrobial composite and a polyethylene film.
(Item 44)
A packaging insert according to any of the preceding items, further comprising one or more of a water absorbent material, an adhesive material, and a water permeable material.
(Item 45)
A packaging insert according to any of the preceding items, further comprising one or more of an antimicrobial composite, a water absorbent layer, an adhesive layer, and a water permeable material.
(Item 46)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the silica-based delivery material is an adsorbent material.
(Item 47)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the silica-based delivery material is a porous solid.
(Item 48)
The composition, antimicrobial complex, or packaging insert of any of the preceding items, wherein the antimicrobial agent is a combination of two or more antimicrobial agents.
(Item 49)
The composition, antimicrobial complex, or packaging insert of any of the preceding items, wherein the antimicrobial agent comprises an essential oil.
(Item 50)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the antimicrobial agent comprises one or more of clove oil, clove extract, vanilla extract, and lemongrass oil.
(Item 51)
a delivery material having an average equivalent circle diameter (CED) particle size of between about 20 μm and about 80 μm and/or an average pore size of between about 50 Å and about 75 Å, and/or
a matrix having an average particle size of an equivalent circle diameter (CED) of between about 20 μm and about 80 μm, and/or
An antimicrobial composite having a basis weight between about 100 g/m ² and about 300 g/m ²
A composition, antimicrobial composite, or packaging insert according to any of the preceding items, comprising:
(Item 52)
The composition, antimicrobial composite, or packaging insert comprises a dispersion medium and a matrix, and the antimicrobial agent is present in the dispersion medium at about 0.01 wt% based on the total weight of the matrix and the dispersion medium. to about 1.5 wt. 52. The composition, antimicrobial composite, or packaging insert of item 51, present in an amount of at least about 50 wt% by weight.
(Item 53)
The silica-based delivery material has an area of about 50 to about 1500 m ² /g, about 100 to about 1500 m ² /g, about 250 to about 1000 m ² /g, about 300 to about 1200 m ² /g, about 350 to about 850 m ^{2 /} g g, from about 400 to about 800 m ² /g, from about 400 to about 600 m ² /g, from about 450 to about 650 m ² /g, from about 600 to about 800 m ² /g, or from about 620 to about 820 m ² /g A composition, antimicrobial composite, or packaging insert according to any preceding item having a surface area.
(Item 54)
The silica-based delivery material is between about 5 Å and about 100 Å, between about 20 Å and about 100 Å, between about 30 Å and about 90 Å, between about 40 Å and about 100 Å, between about 40 Å and about 80 Å, between about 40 Å and about between about 70 Å, between about 40 Å and about 75 Å, between about 40 Å and about 65 Å, between about 50 Å and about 75 Å, between about 50 Å and about 65 Å, between about 55 Å and about 65 Å, or between about 57 Å and about A composition, antimicrobial composite, or packaging insert according to any preceding item having an average pore size of between 63 Å.
(Item 55)
The silica-based delivery material is between about 0.1 mL/g and about 1.5 mL/g, between about 0.3 mL/g and about 1.3 mL/g, between about 0.5 mL/g and about 1.5 mL /g, between about 0.5 mL/g and about 1.3 mL/g, between about 0.5 mL/g and about 1.0 mL/g, between about 0.5 mL/g and about 0.9 mL/g between about 0.6 mL/g to about 1.0 mL/g, between about 0.6 mL/g to about 0.9 mL/g, between about 0.6 mL/g to about 0.8 mL/g , between about 0.7 mL/g and about 1.0 mL/g, between about 0.8 mL/g and about 1.0 mL/g, between about 0.8 mL/g and about 1.5 mL/g, about The composition of any of the preceding items, having an internal void volume of between 0.9 mL/g and about 1.5 mL/g, or between about 0.9 mL/g and about 1.3 mL/g, antimicrobial Composites, or packaging inserts.
(Item 56)
The matrix is between about 5 μm and about 250 μm, between about 10 μm and about 150 μm, between about 10 μm and about 40 μm, between about 10 μm and about 50 μm, between about 20 μm and about 40 μm, between about 25 μm and about 45 μm. between about 20 μm and about 50 μm, between about 20 μm and about 60 μm, between about 30 μm and about 150 μm, between about 50 μm and about 150 μm, between about 60 μm and about 120 μm, or between about 30 μm and about 80 μm , an average particle size of an equivalent circle diameter (CED) of between about 40 μm and about 65 μm, between about 35 μm and about 75 μm, between about 52 μm and about 75 μm, or between about 10 μm and about 80 μm. A composition, antimicrobial composite, or packaging insert as described in any one.
(Item 57)
The antimicrobial complex is between about 10 g/m ² and about 1300 g/m ² , between about 10 g/m ² and about 25 g/m ² , between about 15 g/m ² and about 1300 g/m ² , about 15 g /m ² to about 30 g/m ² , between about 15 g/m ² to about 50 g/m ² , between about 15 g/m ² to about 80 g/m ² , between about 15 g/m ² to about 100 g/m 2 ² , between about 25 g/m ² and about 1300 g/m ² , between about 25 g/m ² and about 100 g/m ² , between about 50 g/m ² and about 150 g/m ² , between about 80 g/m ² to about 150 g/m ² , between about 90 g/m ² and about 150 g/m ² , between about 100 g/m ² and about 200 g/m ² , between about 100 g/m 2 ^and about 300 g/m ² between about 100 g/m ² and about 500 g/m ² , between about 250 g/m ² and about 750 g /m ² , between about 500 g/m ² and about 800 g/m ² , or between about 750 g/m ² An antimicrobial composite according to any preceding item having a basis weight of between to about 1300 g/m ² .
(Item 58)
The dispersion medium is between about 10 g/m ² and about 1300 g/m ² , between about 10 g/m ² and about 25 g/m ² , between about 15 g/m ² and about 1300 g/m ² , between about 15 g/ m 2 between about 15 g/m ² ^and ^about 50 g/m ² between about 15 g/m 2 and about 80 g/m 2 ^between about ¹⁵ g/m ² and about 100 g/m ² between about 25 g/m ² and about 1300 g/m ² between about 25 g/m ² and about 100 g /m ² between about 50 g/m ² and about 150 g/m ² between about 80 g/m ² between about 150 g/m ² between about 90 g/m 2 ^and about 150 g/m ² between about 100 g/m ² and about 200 g/m ² between about 100 g/m ² and about 300 g/m ² , between about 100 g/m ² and about 500 g/m ² , between about 250 g/m ² and about 750 g /m ² , between about 500 g/m ² and about 800 g/m ² , or between about 750 g/m ² An antimicrobial composite according to any of the preceding items having a basis weight of between about 1300 g/m ² .
(Item 59)
Any of the preceding items, wherein the silica-based delivery material comprises at least one of macroporous silica-based materials, mesoporous silica-based materials, and microporous silica-based materials, and related derivatives, and combinations thereof. A composition, antimicrobial composite, or packaging insert according to any one of claims 1 to 3.
(Item 60)
The silica-based delivery material comprises at least one of amorphous silica, fumed silica, particulate silica, ground quartz, particulate, fumed, crystalline and ground silicon dioxide and related derivatives, and combinations thereof. , the composition, antimicrobial composite, or packaging insert of any of the preceding items.
(Item 61)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the silica-based delivery material further comprises one or more of metal oxides, metalloid oxides, and combinations thereof.
(Item 62)
A composition, antimicrobial composite, according to any of the preceding items, wherein said silica-based delivery material further comprises one or more of zinc oxide, titanium oxide, Group 13 or Group 14 oxides, and combinations thereof. , or packaging insert.
(Item 63)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the silica-based delivery material further comprises aluminum oxide.
(Item 64)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the silica-based delivery material further comprises zinc oxide.
(Item 65)
The composition, antimicrobial composite, or packaging insert of any of the preceding items, wherein the silica-based delivery material further comprises a portion of aluminum oxide.
(Item 66)
the antimicrobial agent is present in the silica-based delivery material at between about 0.001 wt% and about 20 wt%, between about 0.05 wt% and about 20 wt%, based on the total weight of the silica-based delivery material and the antimicrobial agent; between about 0.1 wt% and about 20 wt%, between about 0.5 wt% and about 20 wt%, between about 1 wt% and about 20 wt%, between about 1.5 wt% and about 20 wt%, between about 2 wt% % to about 20 wt%, between about 4 wt% and about 20 wt%, between about 5 wt% and about 20 wt%, between about 7 wt% and about 20 wt%, between about 10 wt% and about 20 wt%, about 2 wt% % to about 7 wt%, between about 2 wt% and about 10 wt%, between about 2 wt% and about 15 wt%, between about 4 wt% and about 10 wt%, between about 4 wt% and about 15 wt%, or about The composition, antimicrobial composite, or packaging insert of any of the preceding items, present in an amount between 7 wt% and about 15 wt%.
(Item 67)
The antimicrobial agent is present in the silica-based delivery material between about 0.001 wt% and about 3 wt%, based on the total weight of the silica-based delivery material and the antimicrobial agent, between about 0.03 wt% and about 0.1 wt% %, between about 0.03 wt% and about 0.5 wt%, between about 0.03 wt% and about 1 wt%, between about 0.03 wt% and about 1.5 wt%, between about 0.03 wt% and between about 3 wt%, between about 0.05 wt% and about 1.5 wt%, between about 0.05 wt% and about 3 wt%, between about 0.5 wt% and about 5 wt%, between about 1 wt% and about 5 wt% %, in an amount between about 2 wt% and about 10 wt%.
(Item 68)
The matrix is present in the dispersion medium in an amount of between about 1 wt% and about 80 wt%, between about 5 wt% and about 20 wt%, between about 10 wt% and about 20 wt%, based on the total weight of the dispersion medium and the matrix. between about 10 wt% and about 50 wt%, between about 10 wt% and about 60 wt%, between about 15 wt% and about 50 wt%, between about 15 wt% and about 60 wt%, between about 20 wt% and about 40 wt% between about 20 wt% and about 50 wt%, between about 20 wt% and about 60 wt%, between about 25 wt% and about 40 wt%, between about 30 wt% and about 37 wt%, between about 30 wt% and about 40 wt% between about 30 wt% and about 50 wt%, between about 30 wt% and about 60 wt%, between about 31 wt% and about 37 wt%, between about 32 wt% and about 37 wt%, between about 40 wt% and about 60 wt% or between about 40 wt% and about 75 wt%.
(Item 69)
The dispersion medium is present in the antimicrobial composite at least about 50 wt%, at least about 55 wt%, at least about 60 wt%, at least about 62 wt%, at least about 65 wt%, at least The antimicrobial complex of any of the preceding items, present in an amount of about 70 wt%, at least about 75 wt%, at least about 80 wt%, at least about 85 wt%, at least about 90 wt%, at least about 95 wt%, or at least about 99 wt%. body or packaging insert.
(Item 70)
The dispersion medium is present in the antimicrobial composite between about 50 wt% and about 99 wt%, between about 55 wt% and about 99 wt%, between about 60 wt% and about 99 wt%, based on the total weight of the dispersion medium and the matrix. %, between about 62 wt% and about 99 wt%, between about 65 wt% and about 99 wt%, between about 70 wt% and about 99 wt%, between about 75 wt% and about 99 wt%, between about 50 wt% and about 75 wt% %, between about 55 wt% and about 75 wt%, between about 60 wt% and about 75 wt%, or between about 60 wt% and about 70 wt%. body or packaging insert.
(Item 71)
The delivery material is present in the antimicrobial composite in an amount of between about 1 wt% and about 45 wt%, between about 1 wt% and about 40 wt%, between about 5 wt% and about 45 wt%, based on the total weight of the antimicrobial composite. between about 5 wt% and about 40 wt%, between about 10 wt% and about 45 wt%, between about 10 wt% and about 40 wt%, between about 15 wt% and about 45 wt%, between about 15 wt% and about 40 wt% between about 20 wt% and about 45 wt%, between about 20 wt% and about 40 wt%, between about 25 wt% and about 45 wt%, between about 25 wt% and about 40 wt%, between about 30 wt% and about 44 wt% between about 30 wt% and about 40 wt%, between about 35 wt% and about 45 wt%, or between about 35 wt% and about 40 wt%, or packaging insert.
(Item 72)
The delivery material is in the antimicrobial composite between about 1 wt% and about 45 wt%, between about 1 wt% and about 40 wt%, between about 5 wt% and about 45 wt%, based on the total weight of the matrix and the dispersion medium. %, between about 5 wt% and about 40 wt%, between about 10 wt% and about 45 wt%, between about 10 wt% and about 40 wt%, between about 15 wt% and about 45 wt%, between about 15 wt% and about 40 wt% %, between about 20 wt% and about 45 wt%, between about 20 wt% and about 40 wt%, between about 25 wt% and about 45 wt%, between about 25 wt% and about 40 wt%, between about 30 wt% and about 44 wt% %, between about 30 wt% and about 40 wt%, between about 35 wt% and about 45 wt%, or between about 35 wt% and about 40 wt%. body or packaging insert.
(Item 73)
the antimicrobial agent is in the dispersion medium, between about 0.001 wt% and about 0.005 wt%, between about 0.001 wt% and about 0.01 wt%, based on the total weight of the dispersion medium and the matrix; , between about 0.001 wt% and about 0.05 wt%, between about 0.001 wt% and about 0.1 wt%, between about 0.001 wt% and about 0.5 wt%, between about 0.001 wt% and about between about 0.001 wt% and about 2 wt%, between about 0.001 wt% and about 5 wt%, between about 0.001 wt% and about 10 wt%, between about 0.01 wt% and about 0.1 wt%. between about 0.01 wt% and about 0.1 wt%, between about 0.01 wt% and about 0.15 wt%, between about 0.01 wt% and about 0.2 wt%, between about 0.01 wt% and about 0.1 wt%. between about 0.01 wt% and about 1 wt% between about 0.01 wt% and about 2 wt% between about 0.01 wt% and about 5 wt% between about 0.01 wt% and about 0.5 wt% between about 0.01 wt% and about 1 wt% between about 0.01 wt% and about 2 wt% between about 0.05 wt% and about 0.1 wt% between about 0.05 wt% and about 0.5 wt% between about 0.05 wt% and about 1 wt% between about between about 0.05 wt% and about 2 wt%, between about 0.05 wt% and about 5 wt%, between about 0.05 wt% and about 10 wt%, between about 0.1 wt% and about 0.5 wt%, about between 0.1 wt% and about 1 wt%, between about 0.1 wt% and about 2 wt%, between about 0.1 wt% and about 5 wt%, between about 0.1 wt% and about 10 wt%, between about 0.1 wt% and about 1 wt%. between 5 wt% and about 1 wt%, between about 0.5 wt% and about 2 wt%, between about 0.5 wt% and about 5 wt%, between about 0.5 wt% and about 10 wt%, between about 1 wt% and about between about 1 wt% and about 10 wt% between about 1.5 wt% and about 10 wt% between about 2 wt% and about 10 wt% between about 4 wt% and about 10 wt% between about 5 wt% in an amount between about 10 wt%, between about 7 wt% and about 10 wt%, between about 2 wt% and about 7 wt%, between about 2 wt% and about 10 wt%, or between about 4 wt% and about 10 wt% An antimicrobial complex or packaging insert according to any of the preceding items, present.
(Item 74)
An antimicrobial composite or packaging insert according to any of the preceding items, wherein the antimicrobial composite is at least one of a wettable antimicrobial composite and a water absorbent antimicrobial composite.
(Item 75)
An antimicrobial composite or packaging insert according to any of the preceding items, wherein the dispersion medium is at least one of a wettable dispersion medium and a water absorbent dispersion medium.
(Item 76)
The antibacterial agents include terpenes, terpenoids, phenols, phenolic compounds, thymol, curcumin, carvacrol, bay leaf oil, lemongrass oil, peppermint oil, spearmint oil, wintergreen oil, acacia oil, eucalyptol, limonene, eugenol, Menthol, farnesol, carvone, hexanal, thyme oil, dill oil, oregano oil, neem oil, orange peel oil, lemon peel oil, rosemary oil, cumin seed extract, thyme oil, hexanal, thymol, eugenol and eugenyl acetate, cloves. A composition according to any of the preceding items, comprising oil, clove extract, vanilla oil, vanilla extract, citronellal, and at least one of vanillin, curcumin, methyl salicylate, and methyl jasmonate or derivatives thereof. , antimicrobial complexes, or packaging inserts.
(Item 77)
The antibacterial agents include terpenes, terpenoids, phenols, phenolic compounds, thymol, curcumin, carvacrol, bay leaf oil, lemongrass oil, peppermint oil, spearmint oil, wintergreen oil, acacia oil, eucalyptol, limonene, eugenol, Menthol, farnesol, carvone, hexanal, thyme oil, dill oil, oregano oil, neem oil, orange peel oil, lemon peel oil, rosemary oil, cumin seed extract, thyme oil, hexanal and eugenyl acetate, clove oil, clove extract vanilla oil, vanilla extract, citronellal, and vanillin, methyl salicylate, methyl jasmonate or derivatives thereof, and combinations thereof; body, or packaging insert.
(Item 78)
Moisture activation of the antimicrobial agent from the composition, antimicrobial composite, or packaging insert of any of the preceding items such that the released antimicrobial agent inhibits the action or adverse effects of pathogens or pests. A method comprising the step of releasing.
(Item 79)
The moisture activation reduces the composition, antimicrobial composite, or packaging insert such that water from water vapor condenses on or in the composition, antimicrobial composite, or packaging insert. 79. The method of item 78, comprising exposure to water vapor.
(Item 80)
80. The method of any one of items 78-79, further comprising exposing said composition, antimicrobial composite, or packaging insert directly to liquid water.
(Item 81)
A method comprising exposing a composition comprising an antimicrobial agent stored in a silica-based delivery material to moisture such that the antimicrobial agent is released from the composition.
(Item 82)
82. The method of item 81, wherein the antimicrobial agent is present in the composition in an amount of at least about 0.001 wt% relative to the total weight of the silica-based delivery material and the antimicrobial agent.
(Item 83)
82. The method of item 81, wherein the antimicrobial agent is present in the composition in an amount of at least about 0.001 wt% relative to the total weight of the composition.
(Item 84)
exposing the antimicrobial composite comprising the antimicrobial agent to moisture such that the antimicrobial agent is released from the antimicrobial composite, the antimicrobial composite comprising:
a dispersion medium, and
a silica-based delivery material dispersed in the dispersion medium;
wherein said antimicrobial agent is preserved in said silica-based delivery material prior to release.
(Item 85)
85. The method of item 84, wherein the antimicrobial agent is present in the antimicrobial composite in an amount of at least about 0.001 wt% based on the total weight of the silica-based delivery material and the antimicrobial agent.
(Item 86)
85. The method of paragraph 84, wherein the antimicrobial agent is present in the antimicrobial complex in an amount of at least about 0.001 wt% relative to the total weight of the antimicrobial complex.
(Item 87)
exposing the antimicrobial composite comprising the antimicrobial agent to moisture such that the antimicrobial agent is released from the antimicrobial composite, the antimicrobial composite comprising:
a solid material, and
Silica dispersed in dispersion medium
wherein said antimicrobial agent is preserved in said silica prior to release.
(Item 88)
88. The method of item 87, wherein the antimicrobial agent is present in the antimicrobial composite in an amount of at least about 0.001 wt% based on the total weight of the silica material and the antimicrobial agent.
(Item 89)
88. The method of item 87, wherein the antimicrobial agent is present in the antimicrobial complex in an amount of at least about 0.001 wt% relative to the total weight of the antimicrobial complex.
(Item 90)
A method comprising exposing a package containing produce and a composition comprising said antimicrobial agent to moisture such that the antimicrobial agent is released from the composition.
(Item 91)
A method according to any of the preceding method items, wherein the moisture is expelled by the produce.
(Item 92)
A method according to any of the preceding method items, further comprising reducing microbial and/or fungal activity of said produce.
(Item 93)
wherein the package includes a packaging insert containing the antimicrobial agent, and wherein the exposing step exposes the packaging insert to the moisture such that the antimicrobial agent is released from the packaging insert. A method according to any of the preceding method items, comprising:
(Item 94)
The method of any of the preceding method items, wherein the composition comprises silica and the antimicrobial agent is adsorbed to the silica.
(Item 95)
The method of any of the preceding method items, wherein the composition comprises a silica-based delivery material, and wherein the antimicrobial agent is preserved in the silica-based delivery material prior to release.
(Item 96)
The method of any of the preceding method items, wherein the composition and/or the antimicrobial complex further comprises a dispersion medium.
(Item 97)
97. The method of item 96, wherein the carrier medium comprises a polymeric material.
(Item 98)
98. The method of item 97, wherein the polymeric material comprises cellulose.
(Item 99)
The dispersion medium is between about 10 g/m ² and about 1300 g/m ² , between about 10 g/m ² and about 25 g/m ² , between about 15 g/m ² and about 1300 g/m ² , between about 15 g/ m 2 between about 15 g/m ² ^and ^about 50 g/m ² between about 15 g/m 2 and about 80 g/m 2 ^between about ¹⁵ g/m ² and about 100 g/m ² between about 25 g/m ² and about 1300 g/m ² between about 25 g/m ² and about 100 g /m ² between about 50 g/m ² and about 150 g/m ² between about 80 g/m ² between about 150 g/m ² between about 90 g/m 2 ^and about 150 g/m ² between about 100 g/m ² and about 200 g/m ² between about 100 g/m ² and about 300 g/m ² , between about 100 g/m ² and about 200 g/m ² , between about 100 g/m ² and about 500 g/m ² , between about 250 g/m ² and about 750 g/m ² , between about 500 g/m ² and about 99. The method of any of items 96-98, having a basis weight of between 800 g/m ² , or between about 750 g/m ² and about 1300 g/m ² .
(Item 100)
A method according to any of the preceding method items, wherein said composition and/or said antimicrobial complex further comprises a matrix.
(Item 101)
The matrix is present in the dispersion medium in an amount of between about 1 wt% and about 80 wt%, between about 5 wt% and about 20 wt%, between about 10 wt% and about 20 wt%, based on the total weight of the dispersion medium and the matrix. between about 10 wt% and about 50 wt%, between about 10 wt% and about 60 wt%, between about 15 wt% and about 50 wt%, between about 15 wt% and about 60 wt%, between about 20 wt% and about 40 wt% between about 20 wt% and about 50 wt%, between about 20 wt% and about 60 wt%, between about 25 wt% and about 40 wt%, between about 30 wt% and about 37 wt%, between about 30 wt% and about 40 wt% between about 30 wt% and about 50 wt%, between about 30 wt% and about 60 wt%, between about 31 wt% and about 37 wt%, between about 32 wt% and about 37 wt%, between about 40 wt% and about 60 wt% or between about 40 wt% and about 75 wt%.
(Item 102)
The matrix is between about 5 μm and about 250 μm, between about 10 μm and about 150 μm, between about 10 μm and about 40 μm, between about 10 μm and about 50 μm, between about 20 μm and about 40 μm, between about 25 μm and about 45 μm. between about 20 μm and about 50 μm, between about 20 μm and about 60 μm, between about 30 μm and about 150 μm, between about 50 μm and about 150 μm, between about 60 μm and about 120 μm, or between about 30 μm and about 80 μm , an average particle size of an equivalent circle diameter (CED) of between about 40 μm and about 65 μm, between about 35 μm and about 75 μm, between about 52 μm and about 75 μm, or between about 10 μm and about 80 μm. The method according to any one of
(Item 103)
the antimicrobial agent is in the dispersion medium, between about 0.001 wt% and about 0.005 wt%, between about 0.001 wt% and about 0.01 wt%, based on the total weight of the dispersion medium and the matrix; , between about 0.001 wt% and about 0.05 wt%, between about 0.001 wt% and about 0.1 wt%, between about 0.001 wt% and about 0.5 wt%, between about 0.001 wt% and about between about 0.001 wt% and about 2 wt%, between about 0.001 wt% and about 5 wt%, between about 0.001 wt% and about 10 wt%, between about 0.01 wt% and about 0.1 wt%. between about 0.01 wt% and about 0.1 wt% between about 0.01 wt% and about 0.5 wt% between about 0.01 wt% and about 1 wt% between about 0.01 wt% between about 2 wt%, between about 0.01 wt% and about 5 wt%, between about 0.01 wt% and about 10 wt%, between about 0.05 wt% and about 0.1 wt%, between about 0.05 wt% between about 0.5 wt%, between about 0.05 wt% and about 1 wt%, between about 0.05 wt% and about 2 wt%, between about 0.05 wt% and about 5 wt%, between about 0.05 wt% between about 10 wt%, between about 0.1 wt% and about 0.5 wt%, between about 0.1 wt% and about 1 wt%, between about 0.1 wt% and about 2 wt%, between about 0.1 wt% between about 5 wt%, between about 0.1 wt% and about 10 wt%, between about 0.5 wt% and about 1 wt%, between about 0.5 wt% and about 2 wt%, between about 0.5 wt% and about between about 0.5 wt% and about 10 wt% between about 1 wt% and about 5 wt% between about 1 wt% and about 10 wt% between about 1.5 wt% and about 10 wt% between about between 2 wt% and about 10 wt%, between about 4 wt% and about 10 wt%, between about 5 wt% and about 10 wt%, between about 7 wt% and about 10 wt%, between about 2 wt% and about 7 wt%, about 103. The method of any of items 96-102, present in an amount between 2 wt% and about 10 wt%, or between about 4 wt% and about 10 wt%.
(Item 104)
105. The method of any one of items 96-104, wherein the dispersion medium is at least one of a wettable dispersion medium and a water-absorbent dispersion medium.
(Item 105)
A method according to any one of the preceding method items, wherein said composition and/or said antimicrobial complex is integrated into a packaging insert.
(Item 106)
The method of any one of the preceding method items, wherein the packaging insert further comprises one or more of a water absorbent layer, an adhesive layer, and a water permeable material.
(Item 107)
A method according to any one of the preceding method items, wherein said composition and/or said antimicrobial complex is associated with a package.
(Item 108)
A method according to any one of the preceding method items, wherein the package comprises one or more of a pallet, box, case, punnet, or clamshell.
(Item 109)
A method according to any one of the preceding method items, wherein the composition and/or the antimicrobial composite comprises a polyethylene film.
(Item 110)
The method of any one of the preceding method items, wherein the composition and/or the antimicrobial composite comprises a polymeric material.
(Item 111)
111. The method of item 110, wherein the polymeric material comprises cellulose.
(Item 112)
The method of any one of the preceding method items, wherein the composition and/or the antimicrobial composite comprises one of paper, film, or plastic.
(Item 113)
The method of any one of the preceding method items, wherein the form factor of the composition and/or the antimicrobial composite is one of paper, film, or plastic.
(Item 114)
The method of any one of the preceding method items, wherein the composition and/or the antimicrobial composite further comprises one or more of a water absorbent material, an adhesive material, and a water permeable material.
(Item 115)
A method according to any one of the preceding method items, wherein the silica-based delivery material is an adsorptive material.
(Item 116)
A method according to any one of the preceding method items, wherein the silica-based delivery material is a porous solid.
(Item 117)
The silica-based delivery material has an area of about 50 to about 1500 m ² /g, about 100 to about 1500 m ² /g, about 250 to about 1000 m ² /g, about 300 to about 1200 m ² /g, about 350 to about 850 m ^{2 /} g g, from about 400 to about 800 m ² /g, from about 400 to about 600 m ² /g, from about 450 to about 650 m ² /g, from about 600 to about 800 m ² /g, or from about 620 to about 820 m ² /g The method of any one of the preceding method items having a surface area.
(Item 118)
The method of any one of the preceding method items, wherein the silica-based delivery material has an average pore size of between about 20 Å and about 100 Å.
(Item 119)
The silica-based delivery material is between about 0.1 mL/g and about 1.5 mL/g, between about 0.3 mL/g and about 1.3 mL/g, between about 0.5 mL/g and about 1.5 mL /g, between about 0.5 mL/g and about 1.3 mL/g, between about 0.5 mL/g and about 1.0 mL/g, between about 0.5 mL/g and about 0.9 mL/g between about 0.6 mL/g to about 1.0 mL/g, between about 0.6 mL/g to about 0.9 mL/g, between about 0.6 mL/g to about 0.8 mL/g , between about 0.7 mL/g and about 1.0 mL/g, between about 0.8 mL/g and about 1.0 mL/g, between about 0.8 mL/g and about 1.5 mL/g, about The method of any one of the preceding method items having an internal void volume of between 0.9 mL/g and about 1.5 mL/g, or between about 0.9 mL/g and about 1.3 mL/g. .
(Item 120)
of said method item, wherein said silica-based delivery material comprises at least one of macroporous silica-based materials, mesoporous silica-based materials, and microporous silica-based materials, and related derivatives, and combinations thereof. A method according to any one of paragraphs.
(Item 121)
The silica-based delivery material comprises at least one of amorphous silica, fumed silica, particulate silica, ground quartz, particulate, fumed, crystalline and ground silicon dioxide and related derivatives, and combinations thereof. A method according to any one of the preceding method items.
(Item 122)
The method of any one of the preceding method items, wherein the silica-based delivery material further comprises one or more of metal oxides, metalloid oxides, and combinations thereof.
(Item 123)
The method of any one of the preceding method items, wherein the silica-based delivery material further comprises one or more of zinc oxide, titanium oxide, Group 13 or Group 14 oxides, and combinations thereof.
(Item 124)
The method of any one of the preceding method items, wherein the silica-based delivery material further comprises aluminum oxide.
(Item 125)
The method of any one of the preceding method items, wherein the silica-based delivery material further comprises zinc oxide.
(Item 126)
The method of any one of the preceding method items, wherein the silica-based delivery material further comprises a portion of aluminum oxide.
(Item 127)
the antimicrobial agent is present in the silica-based delivery material at between about 0.001 wt% and about 20 wt%, between about 0.05 wt% and about 20 wt%, based on the total weight of the silica-based delivery material and the antimicrobial agent; between about 0.1 wt% and about 20 wt%, between about 0.5 wt% and about 20 wt%, between about 1 wt% and about 20 wt%, between about 1.5 wt% and about 20 wt%, between about 2 wt% % to about 20 wt%, between about 4 wt% and about 20 wt%, between about 5 wt% and about 20 wt%, between about 7 wt% and about 20 wt%, between about 10 wt% and about 20 wt%, about 2 wt% % to about 7 wt%, between about 2 wt% and about 10 wt%, between about 2 wt% and about 15 wt%, between about 4 wt% and about 10 wt%, between about 4 wt% and about 15 wt%, or about A method according to any one of the preceding method items, present in an amount between 7 wt% and about 15 wt%.
(Item 128)
A method according to any one of the preceding method items, wherein said antimicrobial agent is a combination of two or more antimicrobial agents.
(Item 129)
The method of any one of the preceding method items, wherein the antimicrobial agent comprises an essential oil.
(Item 130)
The method of any one of the preceding method items, wherein the antimicrobial agent comprises one or more of clove oil, clove extract, vanilla extract, and lemongrass oil.
(Item 131)
The method of any one of the preceding method items, wherein the antimicrobial composite is at least one of a wettable antimicrobial composite and a water-absorbent antimicrobial composite.
(Item 132)
The antibacterial agents include terpenes, terpenoids, phenols, phenolic compounds, thymol, curcumin, carvacrol, bay leaf oil, lemongrass oil, peppermint oil, spearmint oil, wintergreen oil, acacia oil, eucalyptol, limonene, eugenol, Menthol, farnesol, carvone, hexanal, thyme oil, dill oil, oregano oil, neem oil, orange peel oil, lemon peel oil, rosemary oil, cumin seed extract, thyme oil, hexanal, thymol, eugenol and eugenyl acetate, cloves. 10. The method of any one of the preceding method items, comprising oil, clove extract, vanilla oil, vanilla extract, citronellal, and at least one of vanillin, curcumin, methyl salicylate, methyl jasmonate or derivatives thereof. Method.
(Item 133)
The antibacterial agents include terpenes, terpenoids, phenols, phenolic compounds, thymol, curcumin, carvacrol, bay leaf oil, lemongrass oil, peppermint oil, spearmint oil, wintergreen oil, acacia oil, eucalyptol, limonene, eugenol, Menthol, farnesol, carvone, hexanal, thyme oil, dill oil, oregano oil, neem oil, orange peel oil, lemon peel oil, rosemary oil, cumin seed extract, thyme oil, hexanal and eugenyl acetate, clove oil, clove extract vanilla oil, vanilla extract, citronellal, and vanillin, methyl salicylate, methyl jasmonate or derivatives thereof, and combinations thereof.
(Item 134)
The composition and/or the antimicrobial complex is between about 10 g/m ² and about 1300 g/m ² , between about 10 g/m ² and about 25 g/m ² , between about 15 g/m ² and about 1300 g/m 2 . ² , between about 15 g/m ² and about 30 g/m ² , between about 15 g/m ² and about 50 g/m 2 , between about 15 g/m ² and about 80 g/m ² , between about 15 g/m ² ² to about 100 g/m ² , between about 25 g/m ² and about 1300 g/m ² , between about 25 g/m ² and about 100 g/m ² , between about 50 g/m 2 ^and about 150 g/m ² between about 80 g/m ² and about 150 g/m ² between about 90 g/m 2 ^and about 150 g /m ² between about 100 g/m ² and about 200 g/m ² between about 100 g/m ² between about 300 g/m ² , between about 100 g/m ² and about 500 g/m ² , between about 250 g/m ² and about 750 g/m ² , between about 500 g/m ² and about 800 g/m ² ; Or the method of any one of the preceding method items, having a basis weight of between about 750 g/m ² and about 1300 g/m ² .

Claims

A composition comprising:
a silica-based delivery material, and
an antimicrobial agent present in said silica-based delivery material in an amount of at least about 0.001 wt% relative to the total weight of said silica-based delivery material and said antimicrobial agent;
A composition, wherein said antimicrobial agent is associated with said silica-based delivery material such that when moisture is introduced into said composition, at least a portion of said antimicrobial agent is released from said composition.

A composition comprising:
a silica-based delivery material, and
an antimicrobial agent present in said silica-based delivery material in an amount of at least about 0.001 wt% by weight of said composition, when moisture is introduced into said composition; , a composition wherein said antimicrobial agent is associated with said silica-based delivery material such that at least a portion of said antimicrobial agent is released from said composition.

A composition comprising:
silica, and
an antimicrobial agent present in said silica in an amount of at least about 0.001 wt% relative to the total weight of said silica and said antimicrobial agent, wherein moisture is introduced into said composition. and said antimicrobial agent is associated with said silica such that at least a portion of said antimicrobial agent is released from said composition.

A composition comprising:
silica, and
an antimicrobial agent, present in said silica in an amount of at least about 0.001 wt% relative to the total weight of said composition, wherein when moisture is introduced into said composition, said A composition, wherein the antimicrobial agent is associated with the silica such that at least a portion of the antimicrobial agent is released from the composition.

A moisture activated composition for the release of an antimicrobial agent comprising:
a silica-based delivery material, and
A composition comprising said antimicrobial agent present in said silica-based delivery material at least about 0.001 wt% relative to the total weight of said silica-based delivery material and said antimicrobial agent.

An antibacterial complex,
a composition according to any one of claims 1 to 5 ; and a dispersion medium , said composition being dispersed in said dispersion medium, and when moisture is introduced into said antimicrobial composite, An antimicrobial composite, wherein said antimicrobial agent is associated with said silica-based delivery material such that at least a portion of said antimicrobial agent is released from said antimicrobial composite.

An antibacterial complex,
comprising a composition comprising silica , and an antimicrobial agent, and a dispersion medium ;
the antimicrobial agent is present in an amount of at least about 0.001 wt% based on the total weight of the antimicrobial composite;
An antimicrobial composite, wherein the antimicrobial agent is associated with the silica such that at least a portion of the antimicrobial agent is released from the composition when moisture is introduced into the composition.

An antibacterial complex,
comprising a silica-based delivery material , and a composition comprising an antimicrobial agent, and a dispersion medium;
the antimicrobial agent is present in an amount of at least about 0.001 wt% based on the total weight of the antimicrobial composite;
An antimicrobial composite, wherein the antimicrobial agent is associated with the silica-based delivery material such that at least a portion of the antimicrobial agent is released from the composition when moisture is introduced into the composition.

An antibacterial complex,
comprising a composition according to any one of claims 1 to 5 dispersed in a solid material, wherein when moisture is introduced into said antimicrobial complex, at least a portion of said antimicrobial agent is absorbed into said antimicrobial complex wherein said antimicrobial agent is associated with said silica-based delivery material such that it is released from said antimicrobial composite.

An antibacterial complex,
comprising the composition of any one of claims 1 to 5 dispersed in a textile material, wherein when moisture is introduced into said antimicrobial composite, at least a portion of said antimicrobial agent is absorbed into said antimicrobial composite wherein said antimicrobial agent is associated with said silica-based delivery material such that it is released from said antimicrobial composite.

An antibacterial complex,
a dispersion medium, and
comprising a matrix comprising the composition of any one of claims 1-5 ,
The matrix is present in the dispersion medium in an amount of at least about 0.001 wt% based on the total weight of the dispersion medium and the matrix, and when moisture is introduced into the antimicrobial composite, the antimicrobial agent is released. An antimicrobial composite, wherein said antimicrobial agent is associated with said silica-based delivery material such that at least a portion thereof is released from said antimicrobial composite.

An antibacterial complex,
an antimicrobial agent present in the antimicrobial composite in an amount of at least about 0.001 wt% relative to the total weight of the antimicrobial composite, wherein when moisture is introduced into the antimicrobial composite, the antimicrobial agent is released. An antimicrobial complex, wherein the antimicrobial agent is associated with at least a portion of the antimicrobial complex such that at least a portion is released from the antimicrobial complex.

An antibacterial complex,
An antimicrobial composite comprising: a delivery material present in said antimicrobial composite in an amount of at least about 20 wt% relative to the total weight of said antimicrobial composite; and an antimicrobial drug associated with said delivery material.

An antibacterial complex,
An antimicrobial composite comprising: a delivery material present in said antimicrobial composite in an amount of up to about 45 wt% relative to the total weight of said antimicrobial composite; and an antimicrobial drug associated with said delivery material.

A packaging insert,
an antimicrobial agent present in the packaging insert in an amount of at least about 0.001 wt% relative to the total weight of the packaging insert, wherein when moisture is introduced into the packaging insert, the A packaging insert wherein the antimicrobial agent is associated with at least a portion of the packaging insert such that at least a portion of the antimicrobial agent is released from the packaging insert.

15. The composition or antimicrobial composite of any one of claims 1-5, 9-10, and 12-14, further comprising a dispersion medium.

17. The composition or antimicrobial composite of any one of claims 1-2, 5-6, 8-11, and 16, wherein said silica-based delivery material comprises silica.

A packaging insert comprising an antimicrobial complex according to any one of claims 6-14 and 16-17 .

A composition according to any one of claims 1-5 and 16-17 , incorporated into an antimicrobial complex.

20. The composition of any one of claims 1-5, 16-17 and 19 integrated into a packaging insert.

A package comprising a packaging insert according to any one of claims 15 and 18 .

22. The package of claim 21 , further comprising produce.

21. The composition, antimicrobial composite, or packaging insert of any one of claims 6-8, 11, and 16-20, wherein the carrier medium comprises a fibrous material.

Any of claims 1-2, 5-6, 8-11, and 16-23, wherein the antimicrobial agent is adsorbed to the inner surface of the silica-based delivery material, the outer surface of the silica-based delivery material, or both. A composition, antimicrobial composite, or packaging insert according to any one of claims 1 to 3.

25. Any one of claims 6, 8-11, and 16-24, wherein the silica-based delivery material and the antimicrobial agent are uniformly dispersed in the dispersion medium and/or contained as heterogeneous domains in the dispersion medium. A composition, antimicrobial composite, or packaging insert according to paragraph.

An antimicrobial composite or packaging insert according to any one of claims 10, 16-20 and 23-25 , wherein said fibrous material comprises wood pulp and/or wood fibres.

The antimicrobial composite, or packaging insert, of any one of claims 6-18 and 23-26, wherein the antimicrobial composite comprises a polyethylene film.

28. The antimicrobial composite or packaging insert of any one of claims 6-8, 11, 16-18, and 23-27, wherein said dispersion medium comprises a polymeric material.

29. The antimicrobial composite or packaging insert of claim 28 , wherein said polymeric material comprises cellulose.

30. The composition , antimicrobial composite, according to any one of claims 1-20 and 23-29, comprising that said composition or antimicrobial composite is or is part of a film , Or a packaging insert.

A packaging insert according to any one of claims 15, 18 and 23-30 , wherein the packaging insert form factor is one of pads.

32. The packaging insert of claim 31 , wherein said pad comprises one or more layers comprising said antimicrobial composite and one or more layers comprising polyethylene film.

33. The packaging insert of any one of claims 15, 18, and 23-32 , further comprising one or more of a water absorbent material, an adhesive material, and a water permeable material.

34. The composition, antimicrobial complex, or packaging insert of any one of claims 1-20 and 23-33, wherein the antimicrobial agent comprises an essential oil.

35. The composition of any one of claims 1-20 and 23-34 , wherein the antimicrobial agent comprises one or more of clove oil, clove extract, vanilla extract, and lemongrass oil, antimicrobial Composites, or packaging inserts.

36. The composition, antimicrobial complex, or packaging insert of any one of claims 1-20 and 23-35, wherein said antimicrobial agent comprises a guaiacol derivative, a phenylpropanoid, and/or oil of wintergreen. .

a delivery material having an average equivalent circle diameter (CED) particle size of between about 20 μm and about 80 μm and/or an average pore size of between about 50 Å and about 75 Å, and/or an equivalent circle diameter of between about 20 μm and about 80 μm (CED) and/or an antimicrobial composite having a basis weight of between about 100 g/m ² and about 300 g/m ² . A composition, antimicrobial composite, or packaging insert according to any one of claims 1 to 3.

The composition of any one of claims 1-2, 5-6, 8-11, and 16-37, wherein said silica-based delivery material has a surface area in the range of about 50 to about 1500 m ² / g. article, antimicrobial complex, or packaging insert.

The composition of any one of claims 1-2, 5-6, 8-11, and 16-38, wherein said silica-based delivery material has an average pore size of between about 5 Å and about 100 Å; Antimicrobial composites, or packaging inserts.

40. The composition of any one of claims 6-8, 11, 16-18, and 23-39, wherein the carrier medium has a basis weight of between about 10 g/ ^m2 and about 1300 g/ ^m2 . article, antimicrobial complex , or packaging insert .

41. The composition, antimicrobial composite, or packaging insert of any one of claims 1-2, 5-6, 8-11, 16-40, wherein said silica-based delivery material is particulate.

The antibacterial agents include terpenes, terpenoids, phenols, phenolic compounds, thymol, curcumin, carvacrol, bay leaf oil, lemongrass oil, peppermint oil, spearmint oil, wintergreen oil, acacia oil, eucalyptol, limonene, eugenol, Menthol, farnesol, carvone, hexanal, thyme oil, dill oil, oregano oil, neem oil, orange peel oil, lemon peel oil, rosemary oil, cumin seed extract, thyme oil, hexanal, thymol, eugenol and eugenyl acetate, cloves Claims 1-20 and 23-41 comprising oil, clove extract, vanilla oil, vanilla extract, citronellal, and vanillin, curcumin, methyl salicylate , methyl jasmonate , and/ or derivatives or combinations thereof . The composition, antimicrobial composite, or packaging insert of any one of Claims 1 to 3.

43. The composition, antimicrobial complex, according to any one of claims 1-20 and 23-42 , wherein the released antimicrobial agent inhibits the action or adverse effect of pathogens or pests. or releasing the antimicrobial agent from the packaging insert by moisture activation.

a method,
A method comprising exposing said composition comprising said antimicrobial agent stored in a silica-based delivery material to moisture such that the antimicrobial agent is released from the composition.

a method,
exposing the antimicrobial composite comprising the antimicrobial agent to moisture such that the antimicrobial agent is released from the antimicrobial composite, the antimicrobial composite comprising :
A method comprising a dispersion medium and a silica-based delivery material dispersed in said dispersion medium, wherein said antimicrobial agent is preserved in said silica-based delivery material prior to release.

a method,
exposing the antimicrobial composite comprising the antimicrobial agent to moisture such that the antimicrobial agent is released from the antimicrobial composite, the antimicrobial composite comprising :
A method comprising: a solid material; and silica dispersed in a carrier medium, wherein said antimicrobial agent is preserved in said silica prior to release.

46. The method of any one of claims 44-45, wherein the silica-based delivery material comprises silica.

a method,
A method comprising exposing a package containing produce and a composition comprising said antimicrobial agent to moisture such that the antimicrobial agent is released from the composition.