JPWO2020109576A5 - - Google Patents
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- JPWO2020109576A5 JPWO2020109576A5 JP2021531314A JP2021531314A JPWO2020109576A5 JP WO2020109576 A5 JPWO2020109576 A5 JP WO2020109576A5 JP 2021531314 A JP2021531314 A JP 2021531314A JP 2021531314 A JP2021531314 A JP 2021531314A JP WO2020109576 A5 JPWO2020109576 A5 JP WO2020109576A5
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- anchor
- catheter device
- distal portion
- circular
- engagement
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- 210000001519 tissues Anatomy 0.000 claims 5
- 230000015572 biosynthetic process Effects 0.000 claims 4
- 230000005489 elastic deformation Effects 0.000 claims 4
- 238000005755 formation reaction Methods 0.000 claims 4
- 230000000717 retained Effects 0.000 claims 3
- 230000000875 corresponding Effects 0.000 claims 2
- 238000002513 implantation Methods 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 230000000452 restraining Effects 0.000 claims 2
- 210000003540 Papillary Muscles Anatomy 0.000 claims 1
- 230000004308 accommodation Effects 0.000 claims 1
- 239000002131 composite material Substances 0.000 claims 1
- 230000001276 controlling effect Effects 0.000 claims 1
- 229910001000 nickel titanium Inorganic materials 0.000 claims 1
- 230000001105 regulatory Effects 0.000 claims 1
- 229910001220 stainless steel Inorganic materials 0.000 claims 1
- 239000010935 stainless steel Substances 0.000 claims 1
Claims (15)
前記カテーテルデバイスの長さに沿って前記カテーテルデバイスの遠位端から前記カテーテルデバイスの近位端に向かって延びるハウジングセクションであって、前記カテーテルデバイスの前記遠位端にある遠位部分と、前記遠位部分の近位側に位置する近位部分とを含む、ハウジングセクションと、
前記ハウジングセクションの前記遠位部分にあり且つ前記身体組織に前記アンカーを取り付けるために前記アンカーを展開するためのアンカー展開機構であって、前記遠位部分に対して遠位方向の外方に向かって前記アンカーを移動させることによって、前記アンカーの収容ポジションから前記アンカーを展開するように構成される、アンカー展開機構と、
展開の前では前記遠位部分において前記アンカー展開機構によってその収容ポジションで保持される前記アンカーであって、前記アンカーは、線を保持するために前記身体組織に埋め込まれるためのものであり、前記アンカーは、前記身体組織と係合するための複数のフックであって、畳まれたポジション及び畳まれていないポジションを有する複数のフックを含み、前記アンカーは弾性材料で作製され、それにより、前記フックは、拘束力の付与によって前記畳まれたポジションに弾性的に変形されることができ、拘束力の付与がなくなると前記畳まれていないポジションに戻り、前記フックは、前記アンカーが前記遠位部分内で前記収容ポジションにある間、前記畳まれたポジションで保持される、前記アンカーとを備え、
前記ハウジングの前記遠位部分は、前記アンカー及び／又は前記アンカー展開機構の対応する非円形形態部と係合するための非円形形状部を有し、それにより、前記アンカーが前記遠位部分に保持される場合に、前記アンカーの移動は、前記非円形形状部と前記非円形形態部との間の係合に起因して、前記遠位部分の長手方向軸の周りの前記アンカーの回動に関して拘束される、カテーテルデバイス。 A catheter device for embedding an anchor in body tissue to attach a wire to said body tissue, comprising:
a housing section extending along the length of the catheter device from the distal end of the catheter device toward the proximal end of the catheter device, the distal portion at the distal end of the catheter device; a housing section including a proximal portion located proximal to the distal portion;
an anchor deployment mechanism at the distal portion of the housing section for deploying the anchor to attach the anchor to the body tissue and extending distally outwardly with respect to the distal portion; an anchor deployment mechanism configured to deploy the anchor from its stowed position by moving the anchor with a
said anchor retained in its stowed position by said anchor deployment mechanism at said distal portion prior to deployment, said anchor being for implantation into said body tissue to retain a line; The anchor comprises a plurality of hooks for engaging the body tissue, the hooks having a collapsed position and an uncollapsed position, the anchor being made of an elastic material, whereby the The hook is elastically deformable to the collapsed position upon application of a restraining force and returns to the uncollapsed position upon removal of the restraining force, the hook allowing the anchor to move toward the distal end. said anchor retained in said collapsed position while in said stowed position within said portion;
The distal portion of the housing has a non-circular configuration for engaging a corresponding non-circular configuration on the anchor and/or the anchor deployment mechanism so that the anchor is positioned on the distal portion. When retained, movement of the anchor is limited to pivoting of the anchor about the longitudinal axis of the distal portion due to engagement between the non-circular feature and the non-circular feature. A catheter device constrained with respect to.
請求項１に記載のカテーテルデバイス。 wherein the anchor is configured to be implanted in the heart, the anchor being a papillary anchor for implantation in a papillary muscle, and the wire being a cord wire;
A catheter device according to claim 1 .
請求項１又は２に記載のカテーテルデバイス。 the non-circular shape is a shape formed within the interior of the distal portion around a recess for receiving the anchor and the anchor deployment mechanism when the anchor is in the stowed position;
A catheter device according to claim 1 or 2.
請求項１、２又は３に記載のカテーテルデバイス。 The anchor includes a locking mechanism having a resiliently deformable locking segment for locking the wire in place after deployment of the anchor, the anchor deployment mechanism wherein the anchor extends from the distal portion to the distal portion. The locking segment is configured to retain the locking segment in a deformed position when housed within the locking segment, the locking segment adopting a non-circular configuration when in the deformed position and in this state, this a non-circular formation engages a portion of the non-circular formation of the distal portion of the catheter device;
4. A catheter device according to claim 1, 2 or 3.
請求項４に記載のカテーテルデバイス。 When the locking segment is not deformed, the locking segment is tubular and aligned with the tubular wall of the anchor; moving the locking segment out of alignment with a wall to form the non-circular formation for engagement with the associated portion of the non-circular formation of the distal portion;
A catheter device according to claim 4.
請求項５に記載のカテーテルデバイス。 The anchor has a circular tubular wall and the deformed locking segment has a non-circular configuration having an ovoid shape, the non-circular configuration comprising a a portion projecting outwardly beyond the tubular wall of the anchor, the distal portion of the catheter device including a corresponding ovoid shape as part of the non-circular shape of the distal portion;
A catheter device according to claim 5.
前記アンカー及び／又は前記遠位部分の遠位端は、ガイド付きの係合を可能にするために、前記アンカーが前記遠位部分と係合する間、弾性的に変形するように構成される、
及び／又は、
前記アンカー展開機構及び／又は前記遠位部分の遠位端は、係合をガイドするためにファネル状の形状のような変化する幅を有する、
カテーテルデバイス。 In the catheter device according to any one of claims 1-6,
A distal end of the anchor and/or the distal portion is configured to elastically deform during engagement of the anchor with the distal portion to enable guided engagement. ,
and/or
the anchor deployment mechanism and/or the distal end of the distal portion has a varying width, such as a funnel-like shape, to guide engagement;
catheter device.
前記アンカー展開機構は、展開中の前記アンカーを保持し且つ前記線の調節を容易にする調節ハウジングを備え、
前記カテーテルデバイスは任意選択的に、
前記調節ハウジングの外側部分は、非円形形状を有し、前記カテーテルデバイスの前記遠位部分の前記非円形形状部の一部は、前記調節ハウジングの前記外側部分と係合することで前記調節ハウジングの回動を拘束するように構成されるという特徴と、
前記アンカー及び前記調節ハウジングは、互いに同軸上で係合するための円形部分を介して互いに係合するように構成され、前記円形部分は、同軸上での配置中の正確な位置合わせを確実にするためのキー付きジョイントを含むという特徴と、
のうちの少なくとも１つを含む、
カテーテルデバイス。 A catheter device according to any one of claims 1 to 7,
the anchor deployment mechanism includes an adjustment housing that holds the anchor during deployment and facilitates adjustment of the line;
Optionally, said catheter device comprises:
An outer portion of the adjustment housing has a non-circular shape, and a portion of the non-circular shaped portion of the distal portion of the catheter device engages the outer portion of the adjustment housing to engage the adjustment housing. A feature of being configured to constrain the rotation of
The anchor and the adjustment housing are configured to engage each other via circular portions for coaxial engagement with each other, the circular portions ensuring accurate alignment during coaxial placement. a feature that includes a keyed joint for
including at least one of
catheter device.
前記遠位部分は、前記アンカーの非円形形態部及び前記調節ハウジングの非円形形態部の両方と係合するように構成される非円形形状部を有し、前記遠位部分の前記非円形形状部は、前記アンカーと係合するための第１部分と、前記調節ハウジングと係合するための第２部分とを有し、
前記カテーテルデバイスは任意選択的に、
前記アンカーと前記遠位部分との再係合中に、前記アンカーの前記非円形形態部と前記遠位部分の前記非円形形状部の関連部分との係合が、前記アンカーの弾性変形及び／又は前記遠位部分の前記遠位端の弾性変形を伴って行われることで、比較的高い度合いの回動不整合に対処し、前記調節ハウジングと前記遠位部分との前記再係合中に、前記調節ハウジングの前記非円形形態部と前記遠位部分の前記非円形形状部の関連部分との係合が、より小さい弾性変形を伴って又は弾性変形を伴わずに行われるように、前記カテーテルデバイスは構成されるという特徴と、
前記カテーテルデバイスは、前記アンカー及び前記アンカー展開機構と前記遠位部分との再係合を容易にするように構成され、この場合、前記カテーテルデバイスは、第１に、前記アンカーと前記遠位部分との再係合が前記アンカーの前記非円形形態部の比較的高い弾性を介して比較的大きな回動不整合を修正することを可能にし、且つ、第２に、前記調節ハウジングの外側部分と前記遠位部分との再係合を有することで、前記アンカーと比較すると前記調節ハウジングの比較的より剛性のある形態に起因して、前記遠位部分内での前記アンカーの回動に対してより大きな拘束を適用するという特徴と、
前記カテーテルデバイスの前記遠位部分の前記非円形形状部の前記第１部分は、前記アンカーが完全に収容される位置から前記カテーテルデバイスの前記遠位端に向かって遠位方向に第１距離だけ延在し、前記カテーテルデバイスの前記遠位部分の前記非円形形状部の前記第２部分は、前記調節ハウジングが完全に収容される位置から前記カテーテルデバイスの前記遠位端に向かって前記遠位方向に第２距離だけ延在し、前記第１距離は前記第２距離よりも大きいという特徴と、
のうちの少なくとも１つを含む、
カテーテルデバイス。 A catheter device according to claim 8, wherein
said distal portion having a non-circular configuration configured to engage both a non-circular configuration of said anchor and a non-circular configuration of said adjustment housing; a portion having a first portion for engaging the anchor and a second portion for engaging the adjustment housing;
Optionally, said catheter device comprises:
During re-engagement of the anchor and the distal portion, the engagement of the non-circular configuration of the anchor with the associated portion of the non-circular configuration of the distal portion may result in elastic deformation and/or elastic deformation of the anchor. or with elastic deformation of the distal end of the distal portion to accommodate a relatively high degree of rotational misalignment and during the re-engagement of the adjustment housing and the distal portion. , such that engagement of the non-circular form of the adjustment housing with the associated portion of the non-circular form of the distal portion occurs with less or no elastic deformation; The feature that the catheter device is configured with
The catheter device is configured to facilitate re-engagement of the anchor and the anchor deployment mechanism with the distal portion, wherein the catheter device first comprises: allows re-engagement with to correct relatively large rotational misalignment via the relatively high resilience of the non-circular form of the anchor, and secondly, the outer portion of the adjustment housing and Having re-engagement with the distal portion prevents pivoting of the anchor within the distal portion due to the relatively stiffer configuration of the adjustment housing compared to the anchor. The feature of applying a larger constraint and
The first portion of the non-circular shape of the distal portion of the catheter device extends a first distance distally toward the distal end of the catheter device from a position where the anchor is fully retracted. The second portion of the non-circular shape of the distal portion of the catheter device extends from a position where the adjustment housing is fully received toward the distal end of the catheter device. extending a second distance in a direction, the first distance being greater than the second distance;
including at least one of
catheter device.
請求項８又は９に記載のカテーテルデバイス。 The adjustment housing forms an anchor holder that connects to the anchor during accommodation and deployment of the anchor, the anchor holder releasing the anchor after successful deployment of the anchor, the anchor holder having at least two provided in two parts, the at least two parts interlocking such that relative rotation between the two parts is prevented by their respective non-circular shapes ;
A catheter device according to claim 8 or 9 .
前記アンカーホルダの前記２つの部分は、前記アンカーと係合するためのピストンと、前記ピストンを保持するためのピストンハウジングとを含み、前記ピストンは、前記ピストンハウジングに対してスライド移動するために作動されることが可能であり、
任意選択的に、前記ピストンは、所望の位置での前記アンカーの展開が成功し前記線が好適な長さに調節されると前記線を切断するための、カッターを含み、
さらに任意選択的に、前記カッター及び／又は前記ピストンホルダは、１つ以上の停止部を備え、前記停止部は、前記カッターが前記カテーテルデバイス内の上方位置及び／又は下方位置を越えて移動するのを防ぐための停止特徴部として作用する、
カテーテルデバイス。 A catheter device according to claim 10, wherein
The two parts of the anchor holder include a piston for engaging the anchor and a piston housing for retaining the piston, the piston operative for sliding movement relative to the piston housing. can be
optionally, said piston includes a cutter for cutting said wire upon successful deployment of said anchor at a desired location and said wire adjusted to a suitable length;
Further optionally, said cutter and/or said piston holder comprise one or more stops, said stops moving said cutter beyond an upper position and/or a lower position within said catheter device. acting as a stop feature to prevent
catheter device.
前記ピストンは、前記アンカーの弾性的に変形可能な係止セグメントと係合するためのピストン楔状部を含み、前記ピストン楔状部は、前記係止セグメントと前記アンカーの壁との間で押圧されることで、前記係止セグメントを弾性的に変形させるように構成され、
前記カテーテルデバイスは
前記ピストン楔状部は、前記係止セグメントとの係合及び係合解除を容易にするために、遠位端にテーパ形状を備えるという特徴と、
前記アンカーホルダ及び前記アンカーは、前記ピストン楔状部が前記係止セグメントと係合する場合に前記ピストン楔状部が前記アンカーの壁から間隔をあけるように構成されるという特徴と、
のうちの少なくとも１つを含む、
カテーテルデバイス。 A catheter device according to claim 11, wherein
The piston includes a piston wedge for engaging an elastically deformable locking segment of the anchor, the piston wedge being pressed between the locking segment and a wall of the anchor. configured to elastically deform the locking segment by
Said catheter device is
characterized in that said piston wedge comprises a tapered shape at its distal end to facilitate engagement and disengagement with said locking segment;
wherein the anchor holder and the anchor are configured such that the piston wedge is spaced from a wall of the anchor when the piston wedge engages the locking segment;
including at least one of
catheter device.
内部カムが、前記アンカー係止セグメントを開ポジションに保持するのを補助するために前記アンカーホルダの一部として設けられ、前記内部カムは、前記係止セグメントの変形されていない状態にある前記係止セグメントの内側に前記カムが収まる非拡張形態と、変形された状態の前記係止セグメントの内側に前記カムが収まる拡張形態とを有し、
任意選択的に、前記カムは、前記非拡張形態よりも前記拡張形態の方が広い開口部を前記カムの中心に有し、前記ピストンは、前記カムの前記開口部をより広い状態に付勢し且つこれ故前記カムを拡張するためのカム楔状部を備え、
さらに任意選択的に、前記ピストンは、前記ピストンの遠位端にフォーク状の形態を有し、前記フォークの少なくとも１つの櫛歯が前記カム楔状体を提供し、前記フォークの少なくとも１つの櫛歯が前記ピストン楔状体を提供する、
カテーテルデバイス。 A catheter device according to claim 12, wherein
An internal cam is provided as part of the anchor holder to assist in holding the anchor locking segment in the open position, the internal cam regulating the locking segment in its undeformed state. a non-expanded configuration in which the cam resides inside the stop segment and an expanded configuration in which the cam resides inside the deformed locking segment;
Optionally, said cam has an opening in the center of said cam that is wider in said expanded configuration than in said non-expanded configuration, and said piston biases said opening of said cam to a wider condition. and thus comprising a cam wedge for expanding said cam,
More optionally, said piston has a forked configuration at a distal end of said piston, at least one comb tine of said fork providing said cam wedge, and at least one comb tine of said fork provides said piston wedge,
catheter device.
前記調節ハウジングは、前記カテーテルデバイスに対する前記調節ハウジングの移動を防ぐために、前記カテーテルデバイスの前記ハウジングセクションと係合するためのラッチ係合部を含み、
任意選択的に、前記ラッチ係合部は、前記ハウジングセクションとの係合及び係合解除への揺動を可能にするために、前記カテーテルデバイスの長手方向軸に沿って延びる軸の周りに枢動されることが可能であり、ワイヤ又はロッドが前記ラッチ係合部の作動のために含まれ、
さらに任意選択的に、前記カテーテルデバイスは、
前記ワイヤ又は前記ロッドは、前記ワイヤ又は前記ロッドが除去されるまで固定状態を保つために前記ラッチ係合部の移動を阻止し、前記ワイヤ又は前記ロッドが除去された時点で、前記ラッチ係合部は、前記ハウジングセクションから係合解除されるポジションに移動するのが自由であるという特徴と、
前記ラッチ係合部は、係合解除ポジションに向かってバネ付勢を受け、それにより、前記ラッチ係合部が解放されると、前記ラッチ係合部は、バネ力の影響下で前記係合解除ポジションに移動するという特徴と、
のうちの少なくとも１つを含む、
カテーテルデバイス。 A catheter device according to any one of claims 8 to 13,
the adjustment housing includes a latch engagement portion for engaging the housing section of the catheter device to prevent movement of the adjustment housing relative to the catheter device;
Optionally, said latch engagement portion pivots about an axis extending along a longitudinal axis of said catheter device to allow rocking into and out of engagement with said housing section. movable, a wire or rod being included for actuation of the latch engagement portion;
More optionally, said catheter device comprises:
The wire or rod blocks movement of the latch engagement portion to remain fixed until the wire or rod is removed, at which point the latch engagement portion is removed. the part is free to move to a position disengaged from said housing section;
The latch engagement portion is spring biased toward a disengaged position such that when the latch engagement portion is released, the latch engagement portion moves toward the engagement position under the influence of spring force. The feature of moving to the release position,
including at least one of
catheter device.
前記カテーテルデバイスは、前記遠位部分に対する前記調節ハウジングの移動を制御するための機構を備え、前記機構は、前記カテーテルデバイスの前記ハウジング内に位置する調節カテーテルを含み、前記調節カテーテルは、前記調節ハウジングを前進又は後退させるために、前記カテーテルデバイスの長さに沿って前方又は後方に移動させられることができる、
及び／又は、
前記遠位部分の前記外形は、前記遠位部分の前記壁の厚さが変化するように、前記非円形形状部とは異なる形状であり、前記遠位部分の前記壁のより厚いセクションは、索チャネルを含む、
及び／又は、
前記ハウジングセクションは、ステンレス鋼、ニチノール、ポリマー材料又は複合材料の１つ以上のチューブ状セクションから形成される、
カテーテルデバイス。 A catheter device according to any one of claims 1 to 14,
The catheter device comprises a mechanism for controlling movement of the adjustment housing relative to the distal portion, the mechanism including an adjustment catheter located within the housing of the catheter device, the adjustment catheter being adapted to control the adjustment housing. can be moved forward or backward along the length of the catheter device to advance or retract the housing;
and/or
the profile of the distal portion is shaped differently than the non-circular shaped portion such that the thickness of the wall of the distal portion varies, the thicker section of the wall of the distal portion comprising: including search channels,
and/or
said housing section is formed from one or more tubular sections of stainless steel, nitinol, polymeric material or composite material;
catheter device.
Applications Claiming Priority (25)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1819480.3 | 2018-11-29 | ||
| GB1819490.2A GB2579388B (en) | 2018-11-29 | 2018-11-29 | Device for heart repair |
| GB1819489.4A GB2579387B (en) | 2018-11-29 | 2018-11-29 | Device for heart repair |
| GBGB1819484.5A GB201819484D0 (en) | 2018-11-29 | 2018-11-29 | Device for heart repair |
| GBGB1819480.3A GB201819480D0 (en) | 2018-11-29 | 2018-11-29 | Device for heart repair |
| GB1819484.5 | 2018-11-29 | ||
| GB1819489.4 | 2018-11-29 | ||
| GB1819490.2 | 2018-11-29 | ||
| GB1820258.0A GB2579420B (en) | 2018-11-29 | 2018-12-12 | Device for heart repair |
| GB1820258.0 | 2018-12-12 | ||
| GB1820990.8 | 2018-12-21 | ||
| GBGB1820990.8A GB201820990D0 (en) | 2018-12-12 | 2018-12-21 | Device for heat repair |
| GBGB1904688.7A GB201904688D0 (en) | 2018-12-12 | 2019-04-03 | Device for heart repair |
| GB1904688.7 | 2019-04-03 | ||
| GB1907110.9 | 2019-05-20 | ||
| GBGB1907110.9A GB201907110D0 (en) | 2019-05-20 | 2019-05-20 | Device for heart repair |
| GB1911812.4 | 2019-08-16 | ||
| GB1911812.4A GB2581545B (en) | 2018-11-29 | 2019-08-16 | Device for heart repair |
| GB1911817.3A GB2581863B (en) | 2018-11-29 | 2019-08-16 | Device for heart repair |
| GB1911817.3 | 2019-08-16 | ||
| GB1913057.4A GB2579433B (en) | 2018-11-29 | 2019-09-10 | Device for heart repair |
| GB1913057.4 | 2019-09-10 | ||
| GB1913360.2 | 2019-09-16 | ||
| GB1913360.2A GB2580994B (en) | 2018-11-29 | 2019-09-16 | Device for heart repair |
| PCT/EP2019/083135 WO2020109576A1 (en) | 2018-11-29 | 2019-11-29 | Device for heart repair |
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| JP2022508301A JP2022508301A (en) | 2022-01-19 |
| JPWO2020109576A5 true JPWO2020109576A5 (en) | 2022-12-07 |
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| JP2021531129A Pending JP2022509308A (en) | 2018-11-29 | 2019-11-29 | Heart repair device |
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| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
| CA3073834A1 (en) | 2017-08-25 | 2019-02-28 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| AU2019374743B2 (en) | 2018-11-08 | 2022-03-03 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
| US11602429B2 (en) | 2019-04-01 | 2023-03-14 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
| CA3140925A1 (en) | 2019-05-20 | 2020-11-26 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
| AU2020295566B2 (en) | 2019-06-20 | 2023-07-20 | Neovasc Tiara Inc. | Low profile prosthetic mitral valve |
| US11850152B2 (en) * | 2019-07-03 | 2023-12-26 | Boston Scientific Scimed, Inc. | Devices, systems, and methods for artificial chordae tendineae |
| CN116407343A (en) * | 2021-12-30 | 2023-07-11 | 杭州德晋医疗科技有限公司 | Valve repairing device capable of being clamped secondarily |
| CN117179963A (en) * | 2022-05-30 | 2023-12-08 | 上海臻亿医疗科技有限公司 | Implant release orientation marking device, implant delivery system and method of operating the same |
| WO2023249916A1 (en) * | 2022-06-21 | 2023-12-28 | Boston Scientific Scimed, Inc. | Devices, systems, and methods for delivering and deploying an implantable device |
| WO2024039534A1 (en) * | 2022-08-19 | 2024-02-22 | Edwards Lifesciences Corporation | Echogenic sutures for cardiac procedures |
| CN115568919A (en) * | 2022-11-24 | 2023-01-06 | 上海安钛克医疗科技有限公司 | Ultrasound guide catheter and ultrasound guided puncture system |
| CN115957049B (en) * | 2023-01-06 | 2023-08-18 | 瀚芯医疗科技(深圳)有限公司 | Valve capture instrument |
| CN115957048A (en) * | 2023-01-06 | 2023-04-14 | 瀚芯医疗科技(深圳)有限公司 | Valve repair system |
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| ATE492219T1 (en) * | 1999-04-09 | 2011-01-15 | Evalve Inc | DEVICE FOR HEART VALVE OPERATION |
| EP2529697B1 (en) * | 2003-12-23 | 2014-01-29 | Sadra Medical, Inc. | Repositionable heart valve |
| EP2026701B1 (en) * | 2006-06-13 | 2016-05-11 | Koninklijke Philips N.V. | Glossopexy tension system |
| US20080195126A1 (en) * | 2007-02-14 | 2008-08-14 | Jan Otto Solem | Suture and method for repairing a heart |
| US8808368B2 (en) * | 2008-12-22 | 2014-08-19 | Valtech Cardio, Ltd. | Implantation of repair chords in the heart |
| US20110011917A1 (en) * | 2008-12-31 | 2011-01-20 | Hansen Medical, Inc. | Methods, devices, and kits for treating valve prolapse |
| US8940002B2 (en) * | 2010-09-30 | 2015-01-27 | Kardium Inc. | Tissue anchor system |
| PT2646105E (en) * | 2010-11-30 | 2015-10-09 | Fabian Hermann Urban Füglister | Helical inserter |
| US9332981B2 (en) * | 2011-05-19 | 2016-05-10 | Abbott Cardiovascular Systems, Inc. | Closure devices and methods |
| EP2863844A4 (en) * | 2012-06-22 | 2015-12-09 | Middle Peak Medical Inc | Device, system, and method for transcatheter treatment of valve regurgitation |
| CN204293210U (en) * | 2014-07-11 | 2015-04-29 | 米特拉利根公司 | Organize anchor system |
| GB2530487B (en) * | 2014-09-17 | 2016-12-28 | Cardiomech As | Device for heart repair |
| US10285809B2 (en) * | 2015-03-06 | 2019-05-14 | Boston Scientific Scimed Inc. | TAVI anchoring assist device |
| WO2017066890A1 (en) * | 2015-10-21 | 2017-04-27 | Coremedic Ag | Medical instrument and method for heart valve repair |
| WO2017079153A1 (en) * | 2015-11-02 | 2017-05-11 | University Of Maryland, Baltimore | Distal anchor apparatus and methods for mitral valve repair |
| CN107252327B (en) * | 2016-10-21 | 2020-05-22 | 塞佩赫·法里亚比 | Tissue attachment device for percutaneous treatment of mitral regurgitation |
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2019
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