JPWO2020041502A5 - - Google Patents
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- JPWO2020041502A5 JPWO2020041502A5 JP2021509772A JP2021509772A JPWO2020041502A5 JP WO2020041502 A5 JPWO2020041502 A5 JP WO2020041502A5 JP 2021509772 A JP2021509772 A JP 2021509772A JP 2021509772 A JP2021509772 A JP 2021509772A JP WO2020041502 A5 JPWO2020041502 A5 JP WO2020041502A5
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Claims (12)
前記機能不全の膀胱及び／または腸が、術後便秘を含む；または
前記機能不全の膀胱及び／または腸が、麻薬誘発性便秘を含む；または
前記機能不全の膀胱及び／または腸が、オピオイド性便秘を含む；または
前記機能不全の膀胱及び／または腸が、外傷または感染などの炎症性刺激によって誘発される機能不全を含む；または
前記機能不全の膀胱及び／または腸が、妊娠関連膀胱及び／または腸機能障害を含む；または
前記機能不全の膀胱及び／または腸が、
髄膜脊髄瘤、糖尿病、ＡＩＤＳ、アルコール乱用、ビタミンＢ１２欠乏性神経障害、椎間板ヘルニア、骨盤手術による障害、梅毒、及び腫瘍
からなる群から選択される状態に関連している、請求項１に記載の磁気刺激装置。 wherein said dysfunctional bladder and/or bowel comprises neurogenic bladder dysfunction; or said dysfunctional bladder and/or bowel comprises postoperative constipation; or said dysfunctional bladder and/or bowel comprises or wherein said dysfunctional bladder and/or bowel comprises opioid constipation; or wherein said dysfunctional bladder and/or bowel is induced by an inflammatory stimulus such as trauma or infection. or said dysfunctional bladder and/or bowel comprises pregnancy-related bladder and/or bowel dysfunction; or said dysfunctional bladder and/or bowel comprises
2. The method of claim 1, associated with a condition selected from the group consisting of: meningomyelia, diabetes, AIDS, alcohol abuse, vitamin B12 deficient neuropathy, disc herniation, injury from pelvic surgery, syphilis, and tumors. magnetic stimulator.
前記磁気刺激装置が、約１Ｈｚの周波数の磁気刺激を与えるように配置される；または
前記磁気刺激装置が、排尿を停止または防止するための約２０Ｈｚから最大約１００Ｈｚの周波数の磁気刺激を与えるように配置される；または
前記磁気刺激が、排尿を停止または防止するための約３０Ｈｚの周波数の磁気刺激を与えるように配置される；または
前記磁気刺激装置が、少なくとも約０．５Ｈｚ、１Ｈｚ、または少なくとも約２Ｈｚ、または少なくとも約３Ｈｚ、または少なくとも約４Ｈｚ、または少なくとも約５Ｈｚ、または少なくとも約１０Ｈｚ、または少なくとも約２０Ｈｚまたは少なくとも約３０Ｈｚまたは少なくとも約４０Ｈｚまたは少なくとも約５０Ｈｚまたは少なくとも約６０Ｈｚまたは少なくとも約７０Ｈｚまたは少なくとも約８０Ｈｚまたは少なくとも約９０Ｈｚまたは少なくとも約１００Ｈｚ、または少なくとも約２００Ｈｚ、または少なくとも約３００Ｈｚ、または少なくとも約４００Ｈｚ、または少なくとも約５００Ｈｚの周波数の磁気刺激を与えるように配置される、請求項１または２に記載の磁気刺激装置。 The magnetic stimulation device is arranged to provide magnetic stimulation at a frequency ranging from about 0.5 Hz up to about 15 Hz to induce urination; or said magnetic stimulation device is arranged to provide magnetic stimulation at a frequency of about 20 Hz up to about 100 Hz to stop or prevent urination; or said magnetic stimulation device is arranged to provide magnetic stimulation at a frequency of about 30 Hz for stopping or preventing 4 Hz, or at least about 5 Hz, or at least about 10 Hz, or at least about 20 Hz, or at least about 30 Hz, or at least about 40 Hz, or at least about 50 Hz, or at least about 60 Hz, or at least about 70 Hz, or at least about 80 Hz, or at least about 90 Hz, or at least about 100 Hz, or 3. A magnetic stimulator according to claim 1 or 2, arranged to provide magnetic stimulation at a frequency of at least about 200 Hz, or at least about 300 Hz, or at least about 400 Hz, or at least about 500 Hz.
前記磁気パルスの持続時間が約２５μｓである、請求項１から３のいずれか一項に記載の磁気刺激装置。 The magnetic stimulation is from about 5 μs, or from about 10 μs, or from about 15 μs, or from about 20 μs up to about 500 μs, or up to about 400 μs, or up to about 300 μs, or up to about 200 μs, or up to about 100 μs, or up to about 4. A magnetic stimulator according to any one of claims 1 to 3, comprising a magnetic pulse of duration in the range of 50 [mu]s; or wherein said magnetic pulse has a duration of about 25 [mu]s.
前記磁気刺激装置が、約３つの連続した刺激時間を含む磁気刺激の１回の治療を与えるように配置される、請求項１から５のいずれか１項に記載の磁気刺激装置。 1, or 2, or 3, or 4, or 5, or 6, or 7, or 8, or 9, or 10, or more in series or said magnetic stimulation device is arranged to provide one treatment of magnetic stimulation comprising about three consecutive stimulation periods; The magnetic stimulation device according to any one of claims 1 to 5.
前記磁気刺激装置が、持続時間が約４分である連続した刺激時間を与えるように配置される、請求項６に記載の磁気刺激装置。 The magnetic stimulator has a duration of from about 10 seconds, or from about 20 seconds, or from about 3 seconds, or from about 40 seconds, or from about 50 seconds, or from about 1 minute, or from about 2 minutes up to about 10 seconds. minutes, or up to about 8 minutes, or up to about 6 minutes; or said magnetic stimulator provides a continuous stimulation time of about 4 minutes in duration. 7. The magnetic stimulation device of claim 6, arranged to:
前記磁気刺激装置が、約３０秒である連続した各刺激時間の間の遅延を与えるように配置される、請求項６または７に記載の磁気刺激装置。 the magnetic stimulator is from about 5 seconds, or from about 10 seconds, or from about 15 seconds, or from about 20 seconds up to about 5 minutes, or up to about 4 minutes, or up to about 3 minutes, or up to about 2 minutes or arranged to provide a delay between each successive stimulation period ranging up to about 1 minute, or up to about 45 seconds, or up to about 30 seconds; 8. A magnetic stimulator according to claim 6 or 7, arranged to provide a delay between each successive stimulation time.
前記磁気刺激装置が、Ｔ１～Ｔ１、Ｔ１～Ｔ２、Ｔ１～Ｔ３、Ｔ１～Ｔ４、Ｔ１～Ｔ５、Ｔ１～Ｔ６、Ｔ１～Ｔ７、Ｔ１～Ｔ８、Ｔ１～Ｔ９、Ｔ１～Ｔ１０、Ｔ１～Ｔ１１、Ｔ１～Ｔ１２、Ｔ２～Ｔ２、Ｔ２～Ｔ３、Ｔ２～Ｔ４、Ｔ２～Ｔ５、Ｔ２～Ｔ６、Ｔ２～Ｔ７、Ｔ２～Ｔ８、Ｔ２～Ｔ９、Ｔ２～Ｔ１０、Ｔ２～Ｔ１１、Ｔ２～Ｔ１２、Ｔ３～Ｔ３、Ｔ３～Ｔ４、Ｔ３～Ｔ５、Ｔ３～Ｔ６、Ｔ３～Ｔ７、Ｔ３～Ｔ８、Ｔ３～Ｔ９、Ｔ３～Ｔ１０、Ｔ３～Ｔ１１、Ｔ３～Ｔ１２、Ｔ４～Ｔ４、Ｔ４～Ｔ５、Ｔ４～Ｔ６、Ｔ４～Ｔ７、Ｔ４～Ｔ８、Ｔ４～Ｔ９、Ｔ４～Ｔ１０、Ｔ４～Ｔ１１、Ｔ４～Ｔ１２、Ｔ５～Ｔ５、Ｔ５～Ｔ６、Ｔ５～Ｔ７、Ｔ５～Ｔ８、Ｔ５～Ｔ９、Ｔ５～Ｔ１０、Ｔ５～Ｔ１１、Ｔ５～Ｔ１２、Ｔ６～Ｔ６、Ｔ６～Ｔ７、Ｔ６～Ｔ８、Ｔ６～Ｔ９、Ｔ６～Ｔ１０、Ｔ６～Ｔ１１、Ｔ６～Ｔ１２、Ｔ７～Ｔ７、Ｔ７～Ｔ８、Ｔ７～Ｔ９、Ｔ７～Ｔ１０、Ｔ７～Ｔ１１、Ｔ７～Ｔ１２、Ｔ８～Ｔ８、Ｔ８～Ｔ９、Ｔ８～Ｔ１０、Ｔ８～Ｔ１１、Ｔ８～Ｔ１２、Ｔ９～Ｔ９、Ｔ９～Ｔ１０、Ｔ９～Ｔ１１、Ｔ９～Ｔ１２、Ｔ１０～Ｔ１０、Ｔ１０～Ｔ１１、Ｔ１０～Ｔ１２、Ｔ１１～Ｔ１１、Ｔ１１～Ｔ１２、Ｔ１２～Ｔ１２、Ｌ１～Ｌ１、Ｌ１～Ｌ２ 、Ｌ１～Ｌ３、Ｌ１～Ｌ４、Ｌ１～Ｌ５、Ｌ１～Ｓ１、Ｌ１～Ｓ２、Ｌ１～Ｓ３、Ｌ１～Ｓ４、Ｌ１～Ｓ５、Ｌ２～Ｌ２ 、Ｌ２～Ｌ３、Ｌ２～Ｌ４、Ｌ２～Ｌ５、Ｌ２～Ｓ１、Ｌ２～Ｓ２、Ｌ２～Ｓ３、Ｌ２～Ｓ４、Ｌ２～Ｓ５、Ｌ３～Ｌ３、Ｌ３～Ｌ４、Ｌ３～Ｌ５、Ｌ３～Ｓ１、Ｌ３～Ｓ２、Ｌ３～Ｓ３、Ｌ３～Ｓ４、Ｌ３～Ｓ５、Ｌ４～Ｌ４、Ｌ４～Ｌ５、Ｌ４～Ｓ１、Ｌ４～Ｓ２、Ｌ４～Ｓ３、Ｌ４～Ｓ４、Ｌ４～Ｓ５、Ｌ５～Ｌ５ 、Ｌ５～Ｓ１、Ｌ５～Ｓ２、Ｌ５～Ｓ３、Ｌ５～Ｓ４、Ｌ５～Ｓ５、Ｓ１～Ｓ１、Ｓ１～Ｓ２、Ｓ１～Ｓ３、Ｓ１～Ｓ４、Ｓ１～Ｓ５、Ｓ２～Ｓ２、Ｓ２～Ｓ３、Ｓ２～Ｓ４、Ｓ２～Ｓ５、Ｓ３～Ｓ３、Ｓ３～Ｓ４、Ｓ３～Ｓ５、Ｓ４～Ｓ４、Ｓ４～Ｓ５、及びＳ５～Ｓ６からなる群から選択される１つ以上の領域にわたる磁気刺激を適用するように配置される；または
前記磁気刺激装置が、Ｔ１１～Ｌ４の間の領域にわたる磁気刺激を適用するように配置される；または
前記磁気刺激装置が、Ｔ１１～Ｔ１２、Ｌ１～Ｌ２、及びＬ２～Ｌ３からなる群から選択される１つ以上の領域にわたる磁気刺激を適用するように配置される；または
前記磁気刺激装置が、Ｌ１～Ｌ２にわたって及び／またはＴ１１～Ｔ１２にわたる磁気刺激を適用するように配置される；または
前記磁気刺激が、Ｌ１にわたる磁気刺激を適用するように配置される、請求項１から９のいずれか一項に記載の磁気刺激装置。 said magnetic stimulator is arranged to apply magnetic stimulation over the thoracic and/or lumbosacral spinal cord; ~T5, T1~T6, T1~T7, T1~T8, T1~T9, T1~T10, T1~T11, T1~T12, T2~T2, T2~T3, T2~T4, T2~T5, T2~T6 , T2-T7, T2-T8, T2-T9, T2-T10, T2-T11, T2-T12, T3-T3, T3-T4, T3-T5, T3-T6, T3-T7, T3-T8, T3 ~T9, T3~T10, T3~T11, T3~T12, T4~T4, T4~T5, T4~T6, T4~T7, T4~T8, T4~T9, T4~T10, T4~T11, T4~T12 , T5-T5, T5-T6, T5-T7, T5-T8, T5-T9, T5-T10, T5-T11, T5-T12, T6-T6, T6-T7, T6-T8, T6-T9, T6 ~T10, T6~T11, T6~T12, T7~T7, T7~T8, T7~T9, T7~T10, T7~T11, T7~T12, T8~T8, T8~T9, T8~T10, T8~T11 , T8-T12, T9-T9, T9-T10, T9-T11, T9-T12, T10-T10, T10-T11, T10-T12, T11-T11, T11-T12, T12-T12, L1-L1, L1 ~ L2 , L1 ~ L3, L1 ~ L4, L1 ~ L5, L1 ~ S1, L1 ~ S2, L1 ~ S3, L1 ~ S4, L1 ~ S5, L2 ~ L2 , L2 ~ L3, L2 ~ L4, L2 ~ L5 , L2-S1, L2-S2, L2-S3, L2-S4, L2-S5, L3-L3, L3-L4, L3-L5, L3-S1, L3-S2, L3-S3, L3-S4, L3 ~S5, L4~L4, L4~L5, L4~S1, L4~S2, L4~S3, L4~S4, L4~S5, L5~L5, L5~S1, L5~S2, L5~S3, L5~S4 , L5-S5, S1-S1, S1-S2, S1-S3, S1-S4, S1-S5, S2-S2, S2-S3, S2-S4, S2-S5, S3-S3, S3-S4, S3 ~ S5, S4-S4, S4-S5, and S5-S6, arranged to apply magnetic stimulation over one or more regions selected from the group consisting of; or the magnetic stimulation device applies magnetic stimulation over one or more regions selected from the group consisting of T11-T12, L1-L2, and L2-L3. or said magnetic stimulation device is arranged to apply magnetic stimulation across L1-L2 and/or across T11-T12; or said magnetic stimulation applies magnetic stimulation across L1 10. A magnetic stimulation device according to any one of claims 1 to 9, arranged to.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862720835P | 2018-08-21 | 2018-08-21 | |
| US62/720,835 | 2018-08-21 | ||
| US201962827782P | 2019-04-01 | 2019-04-01 | |
| US62/827,782 | 2019-04-01 | ||
| PCT/US2019/047551 WO2020041502A1 (en) | 2018-08-21 | 2019-08-21 | Transcutaneous electrical and/or magnetic spinal stimulation for bladder or bowel control in subjects without cns injury |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021533918A JP2021533918A (en) | 2021-12-09 |
| JPWO2020041502A5 true JPWO2020041502A5 (en) | 2023-04-20 |
Family
ID=69591289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021509772A Pending JP2021533918A (en) | 2018-08-21 | 2019-08-21 | Percutaneous electrical and / or magnetic spinal cord stimulation to control the bladder or intestine in subjects without central nervous system damage |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20210236837A1 (en) |
| EP (1) | EP3840825A4 (en) |
| JP (1) | JP2021533918A (en) |
| CA (1) | CA3110189A1 (en) |
| WO (1) | WO2020041502A1 (en) |
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| WO2012094346A2 (en) | 2011-01-03 | 2012-07-12 | The Regents Of The University Of California | High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury |
| ES2728143T3 (en) | 2011-11-11 | 2019-10-22 | Univ California | Transcutaneous spinal cord stimulation: non-invasive tool for locomotor circuit activation |
| DE102012013534B3 (en) | 2012-07-05 | 2013-09-19 | Tobias Sokolowski | Apparatus for repetitive nerve stimulation for the degradation of adipose tissue by means of inductive magnetic fields |
| US9993642B2 (en) | 2013-03-15 | 2018-06-12 | The Regents Of The University Of California | Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion |
| WO2015048563A2 (en) | 2013-09-27 | 2015-04-02 | The Regents Of The University Of California | Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects |
| WO2016029159A2 (en) | 2014-08-21 | 2016-02-25 | The Regents Of The University Of California | Regulation of autonomic control of bladder voiding after a complete spinal cord injury |
| US10773074B2 (en) | 2014-08-27 | 2020-09-15 | The Regents Of The University Of California | Multi-electrode array for spinal cord epidural stimulation |
| US11491342B2 (en) | 2015-07-01 | 2022-11-08 | Btl Medical Solutions A.S. | Magnetic stimulation methods and devices for therapeutic treatments |
| US20180001107A1 (en) | 2016-07-01 | 2018-01-04 | Btl Holdings Limited | Aesthetic method of biological structure treatment by magnetic field |
| US10695575B1 (en) | 2016-05-10 | 2020-06-30 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
| US11266850B2 (en) | 2015-07-01 | 2022-03-08 | Btl Healthcare Technologies A.S. | High power time varying magnetic field therapy |
| US11298533B2 (en) | 2015-08-26 | 2022-04-12 | The Regents Of The University Of California | Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject |
| US11253717B2 (en) | 2015-10-29 | 2022-02-22 | Btl Healthcare Technologies A.S. | Aesthetic method of biological structure treatment by magnetic field |
| US11097122B2 (en) | 2015-11-04 | 2021-08-24 | The Regents Of The University Of California | Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel |
| US11247039B2 (en) | 2016-05-03 | 2022-02-15 | Btl Healthcare Technologies A.S. | Device including RF source of energy and vacuum system |
| US11464993B2 (en) | 2016-05-03 | 2022-10-11 | Btl Healthcare Technologies A.S. | Device including RF source of energy and vacuum system |
| US11534619B2 (en) | 2016-05-10 | 2022-12-27 | Btl Medical Solutions A.S. | Aesthetic method of biological structure treatment by magnetic field |
| US10583287B2 (en) | 2016-05-23 | 2020-03-10 | Btl Medical Technologies S.R.O. | Systems and methods for tissue treatment |
| US10556122B1 (en) | 2016-07-01 | 2020-02-11 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
| DE20168827T1 (en) | 2017-06-30 | 2021-01-21 | Gtx Medical B.V. | NEUROMODULATION SYSTEM |
| WO2019110400A1 (en) | 2017-12-05 | 2019-06-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | A system for planning and/or providing neuromodulation |
| EP3653256B1 (en) | 2018-11-13 | 2022-03-30 | ONWARD Medical N.V. | Control system for movement reconstruction and/or restoration for a patient |
| EP3695878B1 (en) | 2019-02-12 | 2023-04-19 | ONWARD Medical N.V. | A system for neuromodulation |
| CA3116569C (en) | 2019-04-11 | 2023-08-15 | Btl Medical Technologies S.R.O. | Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy |
| US11517760B2 (en) | 2019-05-06 | 2022-12-06 | Kamran Ansari | Systems and methods of treating medical conditions using arrays of planar coils configured to generate pulsed electromagnetic fields and integrated into clothing |
| EP3827871A1 (en) | 2019-11-27 | 2021-06-02 | ONWARD Medical B.V. | Neuromodulation system |
| US11878167B2 (en) | 2020-05-04 | 2024-01-23 | Btl Healthcare Technologies A.S. | Device and method for unattended treatment of a patient |
| CA3173876A1 (en) | 2020-05-04 | 2021-11-11 | Tomas SCHWARZ | Device and method for unattended treatment of a patient |
| US20220151864A1 (en) * | 2020-11-19 | 2022-05-19 | Massachusetts Institute Of Technology | Systems, Devices, and Methods for Gamma Entrainment using Tactile Stimuli |
| US11896816B2 (en) | 2021-11-03 | 2024-02-13 | Btl Healthcare Technologies A.S. | Device and method for unattended treatment of a patient |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6505074B2 (en) * | 1998-10-26 | 2003-01-07 | Birinder R. Boveja | Method and apparatus for electrical stimulation adjunct (add-on) treatment of urinary incontinence and urological disorders using an external stimulator |
| US6701185B2 (en) * | 2002-02-19 | 2004-03-02 | Daniel Burnett | Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues |
| ES2552308T3 (en) * | 2009-09-03 | 2015-11-27 | Murdoch Childrens Research Institute | Transcutaneous stimulation system |
| CA2778963A1 (en) * | 2009-10-26 | 2011-05-05 | Emkinetics, Inc. | Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues |
| US10092750B2 (en) * | 2011-11-11 | 2018-10-09 | Neuroenabling Technologies, Inc. | Transcutaneous neuromodulation system and methods of using same |
| DK3082947T3 (en) * | 2013-12-22 | 2019-06-17 | Univ City New York Res Found | Transspinal DC modulation systems |
| US20150190634A1 (en) * | 2014-01-06 | 2015-07-09 | Ohio State Innovation Foundation | Neuromodulatory systems and methods for treating functional gastrointestinal disorders |
| WO2016029159A2 (en) * | 2014-08-21 | 2016-02-25 | The Regents Of The University Of California | Regulation of autonomic control of bladder voiding after a complete spinal cord injury |
| US11097122B2 (en) * | 2015-11-04 | 2021-08-24 | The Regents Of The University Of California | Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel |
| US10661094B2 (en) * | 2016-04-18 | 2020-05-26 | Wave Neuroscience, Inc. | Systems and methods for spasticity treatment using spinal nerve magnetic stimulation |
-
2019
- 2019-08-21 WO PCT/US2019/047551 patent/WO2020041502A1/en unknown
- 2019-08-21 CA CA3110189A patent/CA3110189A1/en active Pending
- 2019-08-21 JP JP2021509772A patent/JP2021533918A/en active Pending
- 2019-08-21 EP EP19851613.0A patent/EP3840825A4/en active Pending
- 2019-08-21 US US17/269,970 patent/US20210236837A1/en active Pending
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