JPWO2019245913A5 - - Google Patents
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- JPWO2019245913A5 JPWO2019245913A5 JP2020570124A JP2020570124A JPWO2019245913A5 JP WO2019245913 A5 JPWO2019245913 A5 JP WO2019245913A5 JP 2020570124 A JP2020570124 A JP 2020570124A JP 2020570124 A JP2020570124 A JP 2020570124A JP WO2019245913 A5 JPWO2019245913 A5 JP WO2019245913A5
- Authority
- JP
- Japan
- Prior art keywords
- thrombus
- embolectomy device
- embolectomy
- elongated spine
- spine member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 208000007536 Thrombosis Diseases 0.000 claims 39
- 238000013156 embolectomy Methods 0.000 claims 38
- 210000004204 blood vessel Anatomy 0.000 claims 7
- 239000000463 material Substances 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
Claims (12)
前記塞栓除去デバイスの長手方向軸に沿って延びる第１の細長いスパイン部材と、
前記第１の細長いスパイン部材とほぼ平行に、前記塞栓除去デバイスの長手方向軸に沿って延びる第２の細長いスパイン部材と、
第１の複数の血栓係合構造体であって、当該第１の複数の血栓係合構造体のうちの各血栓係合構造体が、前記第１の細長いスパイン部材に連結された第１の端部と、前記第２の細長いスパイン部材に連結された第２の端部とを有する、第１の複数の血栓係合構造体と、
第２の複数の血栓係合構造体であって、当該第２の複数の血栓係合構造体のうちの各血栓係合構造体が、前記第１の複数の血栓係合構造体のうちの対応する血栓係合構造体の第１の端部が前記第１の細長いスパイン部材に連結された位置で、前記第１の細長いスパイン部材に連結された第１の端部と、前記第１の複数の血栓係合構造体のうちの対応する血栓係合構造体の第２の端部が前記第２の細長いスパイン部材に連結された位置で、前記第２の細長いスパイン部材に連結された第２の端部と有する、第２の複数の血栓係合構造体とを備え、
それぞれの血栓係合構造体は、弾力性があり、前記塞栓除去デバイスが血栓と並んで血管内で引き抜かれるときに、前記第１および第２の複数の血栓係合構造体のうちの一方の血栓係合構造体が血管の壁に接触して圧縮し、それにより前記第１および第２の複数の血栓係合構造体のうちの他方の血栓係合構造体と血栓との係合を容易にするバイアス力を提供するように構成され、
前記血栓係合構造体の各々が、それぞれの曲線部分を含み、それら曲線部分が、前記第１の細長いスパイン部材から血栓係合構造体の中央部分に、そして前記中央部分から前記第２の細長いスパイン部材に延び、前記血栓係合構造体のそれぞれの中央部分が、逆Ｖ字形／叉骨のような形態を有することを特徴とする塞栓除去デバイス。 An elongated embolectomy device that is biased to expand from a radially constrained configuration to a radially expanded configuration when released into a blood vessel from a delivery catheter.
A first elongated spine member extending along the longitudinal axis of the embolectomy device,
A second elongated spine member extending along the longitudinal axis of the embolectomy device, substantially parallel to the first elongated spine member.
A first plurality of thrombus engaging structures, wherein each thrombus engaging structure of the first plurality of thrombus engaging structures is connected to the first elongated spine member. A first plurality of thrombus engaging structures having an end and a second end connected to the second elongated spine member.
A second plurality of thrombus engaging structures, wherein each thrombus engaging structure in the second plurality of thrombus engaging structures is among the first plurality of thrombus engaging structures. At the position where the first end of the corresponding thrombus engagement structure is connected to the first elongated spine member, the first end connected to the first elongated spine member and the first elongated spine member. A second end connected to the second elongated spine member at a position where the second end of the corresponding thrombus engagement structure of the plurality of thrombus engaging structures is connected to the second elongated spine member. With a second plurality of thrombus engaging structures having two ends,
Each thrombus engaging structure is elastic and of the first and second thrombus engaging structures when the embolectomy device is withdrawn in a blood vessel alongside the thrombus. One thrombus engaging structure contacts and compresses the wall of the blood vessel, thereby engaging the thrombus with the other thrombus engaging structure of the first and second plurality of thrombus engaging structures. It is configured to provide a bias force that facilitates alignment and
Each of the thrombus engaging structures comprises its own curved portion, which is from the first elongated spine member to the central portion of the thrombus engaging structure and from the central portion to the second elongated portion. An embolectomy device extending into a spine member, each central portion of the thrombus engaging structure having an inverted V-shaped / forked bone-like morphology .
前記塞栓除去デバイスが半径方向に拡張した構成にあるときに、前記第１の複数の血栓係合構造体の中央部分が、前記塞栓除去デバイスの長手方向軸に沿って半径方向外側に延びる実質的に整列した第１の一連のピークを形成し、前記第２の複数の血栓係合構造体の中央部分が、前記塞栓除去デバイスの長手方向軸に沿って半径方向外側に延びる実質的に整列した第２の一連のピークを形成することを特徴とする塞栓除去デバイス。 In the embolectomy device according to claim 1 ,
When the embolectomy device is in a radially extended configuration, the central portion of the first plurality of thrombus engagement structures extends radially outward along the longitudinal axis of the embolectomy device. Forming a first series of peaks aligned with, the central portion of the second plurality of thrombus engagement structures is substantially aligned radially outward along the longitudinal axis of the embolectomy device. An embolectomy device characterized by forming a second series of peaks.
前記塞栓除去デバイスが半径方向に拡張された構成にあるときに、前記血栓係合構造体の中央部分が、前記塞栓除去デバイスの長手方向軸に対して鋭角で遠位方向に延びることを特徴とする塞栓除去デバイス。When the embolectomy device is in a radially extended configuration, the central portion of the thrombus engagement structure is characterized by extending distally at a sharp angle with respect to the longitudinal axis of the embolectomy. Embolectomy device.
前記第１の一連のピークが、前記第２の一連のピークから約１８０°周方向にオフセットされていることを特徴とする塞栓除去デバイス。 In the embolectomy device according to claim 2 .
An embolectomy device characterized in that the first series of peaks is offset about 180 ° circumferentially from the second series of peaks.
ピークが顎の形状であることを特徴とする塞栓除去デバイス。 In the embolectomy device according to claim 2 .
An embolectomy device characterized by a jaw-shaped peak.
前記血栓係合構造体が、非円弧状の形態を有することを特徴とする塞栓除去デバイス。 In the embolectomy device according to claim 1,
An embolectomy device, wherein the thrombus engaging structure has a non-arc shape.
前記第１の複数の血栓係合構造体の血栓係合構造体が、第２の複数の血栓係合構造体の血栓係合構造体と整列していることを特徴とする塞栓除去デバイス。 In the embolectomy device according to any one of claims 1 to 6 .
An embolectomy device comprising the thrombus engaging structure of the first plurality of thrombus engaging structures aligned with the thrombus engaging structure of the second plurality of thrombus engaging structures.
プッシャーワイヤをさらに備え、前記第１および第２の細長いスパイン部材の各々が、前記プッシャーワイヤの遠位端部分に連結されていることを特徴とする塞栓除去デバイス。 In the embolectomy device according to any one of claims 1 to 7 .
An embolectomy device further comprising a pusher wire, wherein each of the first and second elongated spine members is connected to a distal end portion of the pusher wire.
前記第１および第２の細長いスパイン部材が、伸縮抵抗性材料で構成されており、前記塞栓除去デバイスが血管内で近位方向に移動したときに、前記第１および第２の複数の血栓係合構造体がそれぞれ、前記第１および第２の細長いスパイン部材と同時に近位方向に移動して、前記血栓係合構造体と前記血栓との係合を容易にするように構成されていることを特徴とする塞栓除去デバイス。 The embolectomy device according to any one of claims 1 to 8 .
The first and second elongated spine members are made of stretch resistant material and the first and second thrombus engagement when the embolectomy device moves proximally within the blood vessel. The combined structure is configured to move proximally at the same time as the first and second elongated spine members, respectively, to facilitate the engagement of the thrombus engagement structure with the thrombus. An embolectomy device featuring.
前記塞栓除去デバイスが送達カテーテルまたは血管内で移動、前進または後退するときに、前記第１および第２の細長いスパイン部材が、前記塞栓除去デバイスを曲げて長手方向の中立軸に沿って塞栓除去デバイスを整列させるように構成されていることを特徴とする塞栓除去デバイス。 In the embolectomy device according to any one of claims 1 to 9 .
As the embolectomy device moves, advances or retracts within the delivery catheter or blood vessel, the first and second elongated spine members bend the embolectomy device along a longitudinal neutral axis. An embolectomy device characterized by being configured to align.
前記第１および第２の細長いスパイン部材による前記塞栓除去デバイスの整列によって、前記塞栓除去デバイスが血栓に近接して血管内に展開されたときに、それぞれの血栓係合構造体を血栓と整列させることが可能となっていることを特徴とする塞栓除去デバイス。 In the embolectomy device according to claim 10 .
Alignment of the embolectomy devices by the first and second elongated spine members aligns each thrombus engagement structure with the thrombus when the embolectomy device is deployed into the blood vessel in close proximity to the thrombus. An embolectomy device characterized by being able to.
前記塞栓除去デバイスが近位方向に並進されて血管から血栓を除去するときに、それぞれの血栓係合構造体と血栓との整列が維持されることを特徴とする塞栓除去デバイス。 In the embolectomy device according to claim 11 .
An embolectomy device characterized in that the alignment of each thrombus engaging structure with a thrombus is maintained as the embolectomy device is translated proximally to remove a thrombus from a blood vessel.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16/012,426 US10939931B2 (en) | 2018-06-19 | 2018-06-19 | Embolectomy device having multiple embolectomy structures |
| US16/012,426 | 2018-06-19 | ||
| PCT/US2019/037265 WO2019245913A1 (en) | 2018-06-19 | 2019-06-14 | Embolectomy device having multiple embolectomy structures |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021529574A JP2021529574A (en) | 2021-11-04 |
| JPWO2019245913A5 true JPWO2019245913A5 (en) | 2022-05-31 |
| JP7374933B2 JP7374933B2 (en) | 2023-11-07 |
Family
ID=67106169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020570124A Active JP7374933B2 (en) | 2018-06-19 | 2019-06-14 | Embolus removal device with multiple embolus removal structures |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10939931B2 (en) |
| EP (1) | EP3809989B1 (en) |
| JP (1) | JP7374933B2 (en) |
| CN (1) | CN112334083B (en) |
| WO (1) | WO2019245913A1 (en) |
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- 2018-06-19 US US16/012,426 patent/US10939931B2/en active Active
-
2019
- 2019-06-14 JP JP2020570124A patent/JP7374933B2/en active Active
- 2019-06-14 EP EP19734219.9A patent/EP3809989B1/en active Active
- 2019-06-14 WO PCT/US2019/037265 patent/WO2019245913A1/en unknown
- 2019-06-14 CN CN201980040492.8A patent/CN112334083B/en active Active
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