JPWO2019232504A5 - - Google Patents
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- JPWO2019232504A5 JPWO2019232504A5 JP2021516862A JP2021516862A JPWO2019232504A5 JP WO2019232504 A5 JPWO2019232504 A5 JP WO2019232504A5 JP 2021516862 A JP2021516862 A JP 2021516862A JP 2021516862 A JP2021516862 A JP 2021516862A JP WO2019232504 A5 JPWO2019232504 A5 JP WO2019232504A5
- Authority
- JP
- Japan
- Prior art keywords
- cartridge
- tissue
- chamber
- processing chamber
- port
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012545 processing Methods 0.000 claims description 74
- 239000012530 fluid Substances 0.000 claims description 55
- 238000000034 method Methods 0.000 claims description 33
- 238000004891 communication Methods 0.000 claims description 24
- 239000000725 suspension Substances 0.000 claims description 17
- 239000012620 biological material Substances 0.000 claims description 16
- 239000007788 liquid Substances 0.000 claims description 15
- 230000001105 regulatory effect Effects 0.000 claims description 9
- 239000003153 chemical reaction reagent Substances 0.000 claims description 8
- 238000007781 pre-processing Methods 0.000 claims description 5
- 238000002203 pretreatment Methods 0.000 claims description 5
- 239000002699 waste material Substances 0.000 claims description 5
- 238000012546 transfer Methods 0.000 claims description 4
- 230000001276 controlling effect Effects 0.000 claims description 3
- 238000005259 measurement Methods 0.000 claims description 2
- 210000001519 tissue Anatomy 0.000 claims 51
- 210000004027 cell Anatomy 0.000 claims 18
- 239000006285 cell suspension Substances 0.000 claims 12
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 238000001914 filtration Methods 0.000 claims 6
- 210000000130 stem cell Anatomy 0.000 claims 5
- 239000007789 gas Substances 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 3
- 230000014509 gene expression Effects 0.000 claims 3
- 210000004940 nucleus Anatomy 0.000 claims 3
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 2
- 239000011230 binding agent Substances 0.000 claims 2
- 210000002744 extracellular matrix Anatomy 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 101100447432 Danio rerio gapdh-2 gene Proteins 0.000 claims 1
- 108700039887 Essential Genes Proteins 0.000 claims 1
- 101150112014 Gapdh gene Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 230000025164 anoikis Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 210000004413 cardiac myocyte Anatomy 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 239000003599 detergent Substances 0.000 claims 1
- 230000001434 glomerular Effects 0.000 claims 1
- 210000003494 hepatocyte Anatomy 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 210000003470 mitochondria Anatomy 0.000 claims 1
- 210000002569 neuron Anatomy 0.000 claims 1
- 210000003463 organelle Anatomy 0.000 claims 1
- 210000002220 organoid Anatomy 0.000 claims 1
- 210000001711 oxyntic cell Anatomy 0.000 claims 1
- 239000013618 particulate matter Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 230000004083 survival effect Effects 0.000 claims 1
- 210000003171 tumor-infiltrating lymphocyte Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862679466P | 2018-06-01 | 2018-06-01 | |
| US62/679,466 | 2018-06-01 | ||
| PCT/US2019/035097 WO2019232504A2 (en) | 2018-06-01 | 2019-06-01 | Method and apparatus for processing tissue samples |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021525550A JP2021525550A (ja) | 2021-09-27 |
| JPWO2019232504A5 true JPWO2019232504A5 (zh) | 2023-12-04 |
Family
ID=68697143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021516862A Pending JP2021525550A (ja) | 2018-06-01 | 2019-06-01 | 組織サンプルを処理するための方法および装置 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11618876B2 (zh) |
| EP (1) | EP3803324A4 (zh) |
| JP (1) | JP2021525550A (zh) |
| CN (1) | CN112997061A (zh) |
| AU (1) | AU2019279085A1 (zh) |
| CA (1) | CA3102089A1 (zh) |
| WO (1) | WO2019232504A2 (zh) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018102471A1 (en) | 2016-11-29 | 2018-06-07 | S2 Genomics, Inc. | Method and apparatus for processing tissue samples |
| US11618876B2 (en) | 2018-06-01 | 2023-04-04 | S2 Genomics, Inc. | Method and apparatus for processing tissue samples |
| CN117101799A (zh) * | 2019-02-26 | 2023-11-24 | 斯佩克斯样品加工有限责任公司 | 用于研磨大量样品的均质器及方法 |
| IL294956A (en) * | 2020-02-06 | 2022-09-01 | Cutiss Ag | Apparatus and method for isolating cells |
| US20230184641A1 (en) * | 2020-05-18 | 2023-06-15 | S2 Genomics, Inc. | Method and apparatus for processing archived tissue samples |
| US11987787B2 (en) | 2020-07-22 | 2024-05-21 | AVITA Medical Americas, LLC | Devices, methods, and kits for preparing a cell suspension |
| CN113234658B (zh) * | 2021-06-30 | 2023-04-07 | 成都导胜生物技术有限公司 | 一种基于研磨制备存活单细胞的方法 |
| CN113737286B (zh) * | 2021-08-24 | 2022-09-30 | 北京寻因生物科技有限公司 | 单细胞文库制备系统及其控制方法、存储介质 |
| WO2023167974A2 (en) * | 2022-03-02 | 2023-09-07 | S2 Genomics, Inc. | Method and apparatus for processing tissue samples |
| CN115433764A (zh) * | 2022-08-19 | 2022-12-06 | 杭州联川生物技术股份有限公司 | 一种植物细胞核提取的试剂盒及其应用 |
| KR20240043720A (ko) * | 2022-09-27 | 2024-04-03 | 충남대학교병원 | 오가노이드 제작 방법 |
| CN116086710B (zh) * | 2023-04-06 | 2023-06-30 | 北京寻因生物科技有限公司 | 一种单细胞文库制备设备及其密封检测方法和控制装置 |
| CN116626273B (zh) * | 2023-07-21 | 2023-10-03 | 常州科德水处理成套设备股份有限公司 | 一种水处理离子交换树脂分离度测试装置 |
| CN117467532A (zh) * | 2023-10-07 | 2024-01-30 | 浙江基预科技有限公司 | 一种基于纳米孔测序的试剂盒及其控制方法 |
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| US4307846A (en) * | 1979-10-09 | 1981-12-29 | Spelsberg Thomas C | Continuous flow tissue homogenizer |
| US5234809A (en) | 1989-03-23 | 1993-08-10 | Akzo N.V. | Process for isolating nucleic acid |
| US5114858A (en) * | 1990-06-26 | 1992-05-19 | E. I. Du Pont De Nemours And Company | Cellular component extraction process in a disposable filtration vessel |
| GB9411572D0 (en) | 1994-06-09 | 1994-08-03 | Amersham Int Plc | Magnetic bead precipitation method |
| US5705628A (en) | 1994-09-20 | 1998-01-06 | Whitehead Institute For Biomedical Research | DNA purification and isolation using magnetic particles |
| US5830741A (en) | 1996-12-06 | 1998-11-03 | Boehringer Mannheim Corporation | Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease |
| US6190616B1 (en) | 1997-09-11 | 2001-02-20 | Molecular Dynamics, Inc. | Capillary valve, connector, and router |
| US6534262B1 (en) | 1998-05-14 | 2003-03-18 | Whitehead Institute For Biomedical Research | Solid phase technique for selectively isolating nucleic acids |
| CA2374423C (en) | 1999-05-28 | 2013-04-09 | Cepheid | Apparatus and method for analyzing a liquid sample |
| US8815521B2 (en) | 2000-05-30 | 2014-08-26 | Cepheid | Apparatus and method for cell disruption |
| WO2001094911A2 (en) * | 2000-06-09 | 2001-12-13 | Syngenta Participations Ag | System and method for high throughput tissue disruption |
| US20020197631A1 (en) | 2001-04-26 | 2002-12-26 | Lawrence Nathan P. | Multichamber device and uses thereof for processing of biological samples |
| US6739531B2 (en) * | 2001-10-04 | 2004-05-25 | Cepheid | Apparatus and method for rapid disruption of cells or viruses |
| WO2003044213A2 (en) | 2001-11-20 | 2003-05-30 | Genentech, Inc. | Cell and tissue arrays and microarrays and methods of use |
| EP2902501B1 (en) | 2002-01-28 | 2020-04-15 | Life Technologies Corporation | Preparing crude biological extracts using protease, suitable for preparing cDNA |
| US7244961B2 (en) | 2002-08-02 | 2007-07-17 | Silicon Valley Scientific | Integrated system with modular microfluidic components |
| US20040086872A1 (en) | 2002-10-31 | 2004-05-06 | Childers Winthrop D. | Microfluidic system for analysis of nucleic acids |
| US7718421B2 (en) | 2003-02-05 | 2010-05-18 | Iquum, Inc. | Sample processing |
| US20050070944A1 (en) * | 2003-05-15 | 2005-03-31 | Fred Hutchison Cancer Research Center | Method and apparatus for isolating cell nuclei from biopsy obtained tissue |
| JP4226429B2 (ja) | 2003-09-30 | 2009-02-18 | 株式会社貝印刃物開発センター | 医療用ナイフ |
| US20050287670A1 (en) * | 2004-06-29 | 2005-12-29 | Gulliver Eric A | Cell culturing systems, methods and apparatus |
| US7611840B2 (en) * | 2004-08-03 | 2009-11-03 | Agency For Science, Technology And Research | Method and device for the treatment of biological samples |
| US20080307904A1 (en) | 2004-11-10 | 2008-12-18 | Monogen, Inc. | Liquid Specimen Sampling System and Method |
| US20080050814A1 (en) * | 2006-06-05 | 2008-02-28 | Cryo-Cell International, Inc. | Procurement, isolation and cryopreservation of fetal placental cells |
| US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
| US20080306610A1 (en) | 2007-06-07 | 2008-12-11 | Zimmer Orthobiologics, Inc. | Tissue processing for nonimmunogenic implants |
| CN103418295B (zh) * | 2007-06-21 | 2015-11-18 | 简.探针公司 | 用于混合检测腔室的内容物的仪器和方法 |
| WO2010021993A1 (en) | 2008-08-19 | 2010-02-25 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease |
| US9347086B2 (en) | 2009-04-03 | 2016-05-24 | Integrated Nano-Technologies, Llc | Method and system for sample preparation |
| US8536322B2 (en) | 2009-10-19 | 2013-09-17 | Zhiqiang Han | Method for nucleic acid isolation by solid phase reversible binding of nucleic acids |
| EP2540394B1 (en) | 2011-06-27 | 2016-05-04 | Miltenyi Biotec GmbH | Device for fragmenting tissue |
| US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
| AU2013205148B2 (en) | 2013-03-14 | 2014-10-30 | AVITA Medical Americas, LLC | Systems and methods for tissue processing and preparation of cell suspension therefrom |
| US9844782B2 (en) | 2013-06-21 | 2017-12-19 | Coldblock Technologies Inc. | Systems and methods for preparing samples for chemical analysis using a cooled digestion zone |
| CN106536714A (zh) * | 2014-05-30 | 2017-03-22 | 压力生物科技公司 | 样品制备装置及方法 |
| CN113092563A (zh) * | 2014-10-22 | 2021-07-09 | 尹特根埃克斯有限公司 | 用于样品制备、处理和分析的系统和方法 |
| PL3344747T3 (pl) * | 2015-09-04 | 2023-06-19 | Sqz Biotechnologies Company | Wewnątrzkomórkowe dostarczanie biocząsteczek za pośrednictwem powierzchni z porami |
| US11111487B2 (en) | 2015-10-28 | 2021-09-07 | Silicon Valley Scientific, Inc. | Method and apparatus for encoding cellular spatial position information |
| WO2017116694A1 (en) * | 2015-12-29 | 2017-07-06 | 3M Innovative Properties Company | Method and system for detecting microorganisms in large-volume samples |
| CN113567525A (zh) * | 2016-01-13 | 2021-10-29 | 普诺森公司 | 用于毛细管电泳、等电点和分子量分析的系统和方法 |
| JP6953679B2 (ja) * | 2016-03-30 | 2021-10-27 | ソニーグループ株式会社 | 試料分取キット、試料分取装置 |
| US10724089B2 (en) * | 2016-10-06 | 2020-07-28 | The Board Of Trustees Of The University Of Illinois | Spatial molecular analysis of tissue |
| WO2018102471A1 (en) | 2016-11-29 | 2018-06-07 | S2 Genomics, Inc. | Method and apparatus for processing tissue samples |
| US11618876B2 (en) | 2018-06-01 | 2023-04-04 | S2 Genomics, Inc. | Method and apparatus for processing tissue samples |
| WO2020077236A1 (en) | 2018-10-12 | 2020-04-16 | The Broad Institute, Inc. | Method for extracting nuclei or whole cells from formalin-fixed paraffin-embedded tissues |
| US20230184641A1 (en) | 2020-05-18 | 2023-06-15 | S2 Genomics, Inc. | Method and apparatus for processing archived tissue samples |
-
2019
- 2019-06-01 US US15/734,128 patent/US11618876B2/en active Active
- 2019-06-01 EP EP19811211.2A patent/EP3803324A4/en active Pending
- 2019-06-01 CA CA3102089A patent/CA3102089A1/en active Pending
- 2019-06-01 AU AU2019279085A patent/AU2019279085A1/en not_active Abandoned
- 2019-06-01 WO PCT/US2019/035097 patent/WO2019232504A2/en unknown
- 2019-06-01 JP JP2021516862A patent/JP2021525550A/ja active Pending
- 2019-06-01 CN CN201980051401.0A patent/CN112997061A/zh active Pending
-
2023
- 2023-03-09 US US18/119,810 patent/US11926815B2/en active Active
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