JPWO2016051957A1 - Pig weight gain promoting material, pig feed demand rate reducing material and pig stress suppressing material - Google Patents

Abstract

This invention makes it a subject to provide the body weight gain promotion material for pigs, the feed requirement rate reduction material for pigs, and the stress suppression material for pigs, The subject is derived from the polyphenol derived from EFB, the alpha-tocopherol derived from EFB, and EFB. It is solved by a pig weight gain-promoting material characterized by containing at least one or two or more of xyloses and promoting weight gain by administration to pigs. The subject of the present invention is to reduce the feed demand rate expressed by the feed demand rate (-) = feed intake (kg) / weight gain (kg). This is solved by the pig feed demand rate reducing material and the pig stress suppressing material characterized by suppressing pig stress.

Description

  The present invention relates to a body weight gain promoting material for pigs containing an EFB-derived component, a feed requirement reducing material for pigs, and a stress suppressing material for pigs.

  Patent Document 1 discloses a feed additive containing at least one or more of EFB-derived polyphenol, EFB-derived α-tocopherol and EFB-derived xylose. EFB is Empty Fruits Bunch after palm oil is collected from oil palm fruit.

  In this patent document 1, the effect of the additive for feed with respect to a chicken is demonstrated.

JP 2012-131308 A

  The present applicant conducted a test in which an EFB extract was administered by weaning a piglet that had been reared by suckling from a mother pig and changing it to feeding.

  From the analysis of the test results, surprisingly, the administration of EFB extract allows the feed to efficiently contribute to the weight gain of pigs (pig feed demand suppression function) and the function to activate pigs under stress (pig) It was found that the stress resistance activity function) is exerted.

  In view of the fact that pigs subjected to the test are exposed to environmental changes such as weaning, the above function is considered to be a form of expression of functions that promote adaptation to changes in pig breeding environment. And, by this function, a specific function (pig weight gain promoting function) of promoting pig weight gain is exhibited.

  Then, the subject of this invention is providing the weight increase promoter for pigs, the feed requirement rate reduction material for pigs, and the stress suppression material for pigs.

  Other problems of the present invention will become apparent from the following description.

  The above problems are solved by the following inventions.

1.
It contains at least one or more of EFB-derived polyphenol, EFB-derived α-tocopherol and EFB-derived xylose, and promotes weight gain by administering to pigs. Wood.

2.
A feed demand rate reducing material for pigs, comprising the pig weight gain promoting material described in 1 above, wherein the feed demand rate represented by the following formula (1) is reduced.
Feed demand rate (-) = feed intake (kg) / weight gain (kg) (1)

3.
2. A porcine stress suppressor comprising the pork gain-promoting material according to 1 above, which suppresses pig stress.

  ADVANTAGE OF THE INVENTION According to this invention, the increase promotion material for pigs, the feed requirement rate reduction material for pigs, and the stress suppression material for pigs can be provided.

The graph which shows the growth curve in an Example and a comparative example The graph which shows the body weight gain of the individual who developed diarrhea in Examples and Comparative Examples

  Below, the form for implementing this invention is demonstrated.

  The pig weight gain promoter of the present invention promotes pig weight gain by administering it to pigs.

  It is presumed that the function of promoting pig weight gain is exerted, for example, by promoting adaptation to changes in pig breeding environment.

  In one expression form, from the viewpoint that “the feed efficiently contributes to the weight gain of the pig (that is, the feed requirement rate is reduced)”, the pig weight gain promoting material of the present invention is a pig feed. It can be a demand rate reducing material.

  In another expression form, from the viewpoint of “suppressing pig stress”, the pig weight gain promoting material of the present invention can be a pig stress suppressing material.

1. The pig weight gain promoter The pig weight gain promoter of the present invention contains at least one or more of EFB-derived polyphenols, EFB-derived α-tocopherols, and EFB-derived xyloses, and is administered to pigs. This facilitates adaptation to changes in the breeding environment.

  The EFB-derived polyphenol, the EFB-derived α-tocopherol, and the EFB-derived xylose are contained in the EFB extract extracted from the EFB, and the EFB extract is obtained by hydrothermally treating EFB, for example. .

  The term “derived from EFB” means that the EFB extract is used as it is or after being appropriately treated as a body weight gain promoting material for pigs.

  The pig weight gain promoter may be either liquid or solid.

  The polyphenol derived from EFB is a generic term for compounds having a plurality of phenolic hydroxyl groups in one molecule contained in an EFB extract. Specific examples include catechins, anthocyanins, flavones, isoflavones, flavans, and flavanones. And flavonoids such as chlorogenic acid, ellagic acid, lignan, curcumin, and those classified into normal polyphenols such as coumarin.

  It is preferable that the pig weight gain accelerator contains 1 to 15% by weight of polyphenols on a dry basis. The weight percent on a dry basis refers to the weight percent of the pig weight gain promoter, excluding water (hereinafter the same).

  The content of the above polyphenol was determined by adding an 80% ethanol solution to a pig weight gain promoter and bathing in water at 80 ° C. for 30 minutes, and then centrifuging at 1600 × g for 10 minutes, and the resulting supernatant was sampled. It is a value as a gallic acid equivalent amount measured by the Folin-Denis method as a solution.

  The α-tocopherol derived from EFB is α-tocopherol contained in the EFB extract, and specific examples include DL-α-tocopherol, DL-α-tocopherol acetate, DL-α-tocopherol succinate and the like. It can be illustrated.

  It is preferable that the pig weight gain accelerator contains 1 to 30 mg / 100 g of α-tocopherol on a dry basis. The mg / 100 g on a dry basis refers to the weight% of the feed additive excluding water.

  The content of α-tocopherol is a value measured by an HPLC method.

  EFB-derived xylose is a compound containing xylose or xylose contained in an EFB extract as a partial structure. Examples of the compound containing xylose as a partial structure include an oligomer or a polymer of xylose. In particular, xylose derived from EFB preferably contains xylooligosaccharide. The presence of xylooligosaccharides as xylose derived from EFB has been confirmed by analysis. Xylooligosaccharides act as so-called prebiotics and contribute to the health of the pig's intestines, thereby exerting a wide range of health effects such as direct defense against diarrhea and constipation, infection protection, immune response adjustment, etc. be able to.

  It is preferable that the pig weight gain promoter contains 1 to 15% by weight of xylose on a dry basis.

  The content of the above xyloses was determined with respect to the liquid obtained by stirring the feed additive under 72% to 45% sulfuric acid for 1 hour at room temperature, diluting to 2% sulfuric acid concentration, and autoclaving at 121 ° C for 1 hour. It is a value obtained by quantifying xylose by liquid chromatography (HPLC method). That is, in addition to the xylose contained in the feed additive, xylose produced by decomposition of a compound containing xylose as a partial structure is also a combined value.

  The body weight gainer for pigs is either EFB-derived polyphenol and EFB-derived xylose, EFB-derived polyphenol and EFB-derived α-tocopherol, or EFB-derived xylose and EFB-derived It is preferable to contain 2 types of α-tocopherol, and it is particularly preferable to include 3 types of polyphenol derived from EFB, α-tocopherol derived from EFB and xylose derived from EFB.

  According to the pig weight gain promoting material of the present invention, pig weight gain is promoted by administering it to pigs. It is presumed that the function of promoting pig weight gain is exerted, for example, by promoting adaptation to changes in pig breeding environment.

  For example, when weaning a piglet that has been bred by suckling from a mother pig and changing it to breeding with feed, the growth can be suitably maintained, so that the body weight can be increased stably.

  In particular, since the difference in body weight generated during the piglet period (growth period) is difficult to reverse in subsequent growth, promoting adaptation to the breeding environment contributes to the rapid weight gain.

  By being able to increase the weight of a pig quickly, for example, it is possible to shorten the period until it reaches a certain weight and is shipped. There is also an advantage that feed cost can be reduced by shortening the breeding period.

2. Feed requirement reduction material for pigs The feed requirement reduction material for pigs of the present invention is composed of the above-mentioned pig weight gain promoting material, and reduces the feed requirement rate represented by the following formula (1).

Feed demand rate (-) = feed intake (kg) / weight gain (kg) (1)
Here, the feed intake is the weight of the feed taken by one individual pig.
Further, the weight gain is the amount of weight gain in one individual pig.

  That is, it can be said that “reducing the feed request rate” means “making the feed efficiently contribute to the weight gain of the pig”. Thereby, the weight of the pig feed consumed until it becomes a fixed body weight can be reduced. That is, the effect of reducing the cost of pig feed can be obtained.

  For pigs whose feed demand rate is likely to increase due to changes in the breeding environment, preventing the feed demand rate from increasing is to promote adaptation to environmental changes from one viewpoint.

  Moreover, according to the feed requirement reduction material for pigs of this invention, the effect demonstrated about the weight increase promoter for pigs of this invention is also show | played.

3. The stress-suppressing material for pigs The stress-suppressing material for pigs of the present invention comprises the above-described pig weight gain promoting material and suppresses the stress of pigs.

  “Pig stress” causes, for example, diarrhea.

  “Suppression of pig stress” includes, for example, preventing a decrease in pig weight gain under stress.

  By suppressing the stress of pigs, an effect of stably increasing the gain of pigs can be obtained.

  Moreover, even if it is a case where it is difficult to remove the cause of stress, for example, the gain of a pig can be increased stably. For example, the amount of gain can be stably increased without suppressing the occurrence of diarrhea.

  In order to reduce the risk of pigs that are susceptible to stress due to changes in the breeding environment, one aspect is to promote adaptation to environmental changes.

  Moreover, according to the stress suppression material for pigs of this invention, the effect demonstrated about the weight increase promoter for pigs of this invention is also show | played.

4). Administration: Addition to feed In the following, the administration of pig weight gain-promoting material to pigs will be explained, but the same applies to pig feed requirement reduction materials and pig stress suppression materials.

  It is preferable to add the pig weight gain-promoting material to the pig feed and administer it to the pig. In particular, it is preferable to administer a part of the grain contained in the pig feed as a main component to the pig feed. As an alternative grain, for example, corn can be preferably exemplified.

  When adding pig weight gain promoter to pig feed and administering it to pigs, the proportion of pig weight gain promoter in pig feed is not particularly limited, but is in the range of 0.05 to 20% by weight on a dry basis. Preferably, it is in the range of 0.15 to 10% by weight on a dry base, and most preferably in the range of 0.25 to 5% by weight on a dry base.

  In addition, for example, when part of corn in pig feed is replaced with a pig weight gain promoter, the amount of corn replacement (or reduction) is not particularly limited, but is in the range of 0.1 to 40% by weight. Is preferred.

  According to the pig weight gain promoting material, when a part of the grain in the pig feed is replaced, there is an effect that the performance of the pig feed is hardly lowered by the replacement. Specifically, the feed requirement rate of the replaced pig feed can be set to a value similar to or less than the feed requirement rate of the non-substituted pig feed. That is, a part of the grain can be replaced without increasing the feed requirement of the pig feed.

  Thereby, since the grain in pig feed can be suitably replaced by an EFB extract that can be obtained at a relatively low cost, cost reduction can be realized without impairing the performance of pig feed.

5. Other: Significance to reduce grain dependence The ability to reduce the amount of grain used in pig feed has great significance.

  In recent years, as globally important problems, food shortages due to population growth and fossil fuel depletion are becoming more serious. This can be said to be a critical situation for industrial development and for humanity.

  On the other hand, pig breeding is prevalent worldwide, and there is a fact that a huge amount of grain is consumed as pig feed.

  Reducing cereal dependence in pig feed can relatively increase the cereals that can be supplied as human food or as a raw material for biofuels (such as bioethanol) that replace fossil fuels.

  Even if only a part of the grain in pig feed is reduced, if this technology is spread worldwide, consumption of large quantities of grain can be suppressed. And since the replacement with the EFB extract can reduce the cost without impairing the performance of the pig feed and reduce the burden on the pig livestock industry, this technology has the potential to spread worldwide. . This is expected to alleviate problems such as food shortages due to population growth and fossil fuel depletion.

  Examples of the present invention will be described below, but the present invention is not limited to these examples.

  In the following breeding test, the effects on growth and the like when a pig weight gainer was supplied to pigs (milk piglets) were examined.

  In the test, 24 LW / D steers of about 24 days of age were used, and a control group (Comparative Example 1) was fed with a control diet without the addition of a pig weight gain promoter, and 6 of the corn in the control diet were used. Set up a total of 2 test areas (Example 1) to feed test feeds with the amount of% replaced with pig weight gain promoters, assign 4 test pigs to each area, and feed each feed constantly for 28 days Then, the growth performance was investigated. This was implemented as 3 blocks.

1. Materials and Methods (1) Test pigs About 24 days old LW • D steers 24 pigs (body weight 6.8-8.1 kg) were introduced in two portions. That is, it was divided into the first time: 8 (Block 1), the second time: 16 (Block 2 and Block 3)). After quarantine at the time of introduction, the animals were divided into 6 groups of 4 animals, and the control feeds described later were fed for 2 days in Block 1 and 3 days in Block 2 and Block 3 and preliminarily raised and used for the test.

(2) Pig weight gain promoter The pig weight gain promoter used was a wet base (water content 48.5%), EFB-derived polyphenol 3.22% by weight, EFB-derived α-tocopherol 7 .8 mg / 100 g and 2.25 wt% of EFB-derived xylose has been confirmed. In terms of dry base, it contains 6.25% by weight of polyphenol derived from EFB, 15.1 mg / 100 g of α-tocopherol derived from EFB, and 4.37% by weight of xylose derived from EFB.

(3) Setting of test plots, etc. The control plot fed with the control feed without the addition of pig weight gain promoter, and the test feed (test feed with 6% by weight of the corn in the control feed replaced with the pig feed booster) The total proportion of the test plots for supplying the pig weight gain promoter was 3.11% by weight). One group of test pigs was assigned to each ward so that the weight distribution was almost uniform, and was raised for 28 days. This was implemented as 3 blocks.

  Table 1 shows the proportions of the feeds fed to the test group and the control group.

  In Table 1, vitamin B group mixture in 1 kg is 1.0 g of thiamine nitrate, 7.0 g of riboflavin, 0.5 g of pyridoxine hydrochloride, 6.0 g of nicotinamide, 10.9 g of calcium D-pantothenate, 57 of choline chloride .6g included.

  In Table 1, the vitamin A, D and E mixture comprises 10,000 IU of vitamin A oil, 2,000 IU of vitamin D3 oil, and 10 mg of dl-α-tocopherol acetate in 1 kg.

  In Table 1, the trace mineral mixture contains Mn: 50 g, Fe: 50 g, Cu: 10 g, Zn: 60 g, I: 1 g in 1 kg.

(4) Feeding management The test pigs were group-fed for each ward in a 1.8 × 2.7 m concrete floor pig bunch in an open piggery. Feed and drinking water were constantly fed. The bedding used sawdust, and a heat insulation mat and a heat insulation box were installed in each pig bunch. In addition, an oil stove was installed in the passage in the pig house and heated for 24 hours. No vaccination was carried out.

2. Survey item (1) Body weight and weight gain The body weight was measured at intervals of one week from the start of the test, and the weight gain was calculated.

(2) Feed intake and feed request rate The feed intake during each body weight measurement day was measured for each section, and the feed intake and feed request rate per head were calculated.

(3) Health condition The health condition of each individual was observed twice a day in the morning and evening at almost a fixed time. The occurrence of diarrhea was observed by classifying into the following four evaluation criteria. Moreover, it can be evaluated as a normal range until "1: soft stool".

<Evaluation criteria>
0: Normal stool (normal)
1: Soft stool (slightly good)
2: Mud stool (somewhat bad)
3: Water stool (bad)

3. Test period (breeding period)
・ Block 1; January 16 to February 13, 2014 ・ Block 2; January 24 to February 21, 2014 ・ Block 3; January 24 to February 21, 2014

4). Test site: Science Feed Research Center, Japan Scientific Feed Association (821 Yoshikura, Narita, Chiba)

5. Test results and evaluation The test results described below are based on measured value data shown in Tables 5 to 9 later. In the analysis of the results, the individual (block 1 test section No. 64, block 3 control section No. 76 and test section No. 77) that was judged to be an abnormal value by performing a rejection test for each group with respect to the weight gain was obtained. Excluding retroactively at the start of the study and summarizing the test results, the differences between the two sections were examined in terms of weight gain, feed intake, and feed demand rate.

-Growth curve The growth curve of 3 blocks average of both wards was shown in FIG. From FIG. 1, it can be seen that the growth curve has changed almost smoothly in both wards.

-Growth performance Table 2 shows the results of growth gain, feed intake and feed demand rate.

In Table 2, numbers in parentheses are indices when the control group is 100.
The weight gain was an average of 3 blocks, with the test group 17% more than the control group.
Feed intake was an average of 3 blocks, with the test group 16% higher than the control group.
The feed request rate is a value obtained by dividing the feed intake (kg / head) by the body weight gain (kg / head), and a smaller value is preferable. The feed demand rate was an average of 3 blocks, and the test group showed a result that was superior (smaller) than the control group.

  This result shows that the pig weight gain promoting material functions as a feed requirement reduction material for pigs.

・ Health condition In the observation of the health condition, the excretion of mud stool was continued from the start of the test to the end of the test in one of the control sections of Block 2 (individual number 82 in the measured value data shown in FIGS. 3 to 5). Was recognized. Although there was no abnormality in the vitality of the individual, the coat was rough and rigid.

  The occurrence of diarrhea is shown in Table 3. Table 3 shows the ratio (%) of the number of observation days to the total number of days in which the severe results (results of the more severe symptoms) of the observations twice a day were tabulated as the observation results for the day. In both wards, individuals with the excretion of soft stool to mud stool were found.

  In Table 3, numbers in parentheses are indices when the control group is 100.

-Body weight gain in individuals who developed diarrhea Table 4 shows the body weight gain in individuals who developed diarrhea. Here, the pigs that showed symptoms above “2: mud stool” in the evaluation criteria for the occurrence of diarrhea described above were classified as individuals who developed diarrhea. Specifically, individual numbers 66, 68, 71, 74, 82, 86, 79, and 81 in the measurement data shown in Tables 5 to 9 are individuals having diarrhea in the control group, and individual numbers 65 and 70 are used. 72, 80, 84, 88, 73 and 89 were individuals who developed diarrhea in the test plot.

  In Table 4, () is an index when the average of the increase in weight of all individuals in the control group is 100. A bar graph of this index is shown in FIG.

  From Table 4 and FIG. 2, in the control group, the average increase in the body weight decreased in the individuals who developed diarrhea. In contrast, in the test plot, an average decrease in weight gain was prevented in individuals who developed diarrhea.

  This result shows that the pig weight gain promoting material functions as a stress suppressing material for pigs.

  The measured value data of each test is as shown in Tables 5 to 9 below.

Claims (3)

  It contains at least one or more of EFB-derived polyphenol, EFB-derived α-tocopherol and EFB-derived xylose, and promotes weight gain by administering to pigs. Wood. A feed requirement reduction material for pigs, comprising the pig weight gain promoting material according to claim 1, wherein the feed requirement rate represented by the following formula (1) is reduced.
Feed demand rate (-) = feed intake (kg) / weight gain (kg) (1)   A porcine stress suppressant comprising the pork gain-promoting material according to claim 1, which suppresses pig stress.

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