JPWO2009145116A1 - Nerve extension device - Google Patents

Nerve extension device Download PDF

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JPWO2009145116A1
JPWO2009145116A1 JP2010514455A JP2010514455A JPWO2009145116A1 JP WO2009145116 A1 JPWO2009145116 A1 JP WO2009145116A1 JP 2010514455 A JP2010514455 A JP 2010514455A JP 2010514455 A JP2010514455 A JP 2010514455A JP WO2009145116 A1 JPWO2009145116 A1 JP WO2009145116A1
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nerve
rod
moving
cut
thread
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康正 西浦
康正 西浦
直之 落合
直之 落合
友紀 原
友紀 原
浩三 小林
浩三 小林
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University of Tsukuba NUC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/02Devices for expanding tissue, e.g. skin tissue

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Abstract

本発明の課題は、切断された神経の両端部のそれぞれを縫合可能な長さにまで緩徐的に伸長するための神経伸長器具(1)を提供することである。その解決手段としての本発明の神経伸長器具(1)は、切断された神経の両端部のそれぞれを牽引して伸長するための器具であって、棒状部材(2)に対し、骨に挿入する少なくとも2本のピン(3)を保持する保持部材(4)を中央部付近に備え、保持部材(4)の両側に棒状部材(2)の端部方向に移動可能な移動部材(5)を備え、さらに、一方の末端が移動部材(5)に固定され、他方の末端が神経の端部を把持する把持部材(6)に固定された糸状部材(7)をガイドするガイド部材(8)を保持部材(4)と移動部材(5)の間に備え、移動部材(5)を棒状部材(2)の端部方向に移動させることで、切断された神経の端部を糸状部材(7)で牽引して伸長することができるようにしたことを特徴とする。The subject of this invention is providing the nerve extending | stretching instrument (1) for extending | stretching slowly to the length which can sew each of the both ends of the cut | disconnected nerve. The nerve extension device (1) of the present invention as a solution to the problem is a device for pulling and extending both ends of the cut nerve and is inserted into the bone with respect to the rod-like member (2). A holding member (4) holding at least two pins (3) is provided in the vicinity of the central portion, and a movable member (5) movable in the direction of the end of the rod-like member (2) is provided on both sides of the holding member (4). And a guide member (8) for guiding a thread-like member (7) whose one end is fixed to the moving member (5) and whose other end is fixed to a gripping member (6) that holds the end of the nerve. Between the holding member (4) and the moving member (5), and moving the moving member (5) in the direction of the end of the rod-shaped member (2), the end of the cut nerve is threaded (7 ) And can be extended by being pulled.

Description

本発明は、外傷などによって直接的に縫合できない神経欠損間隙が生じた場合や、腫瘍などの切除の際に神経も切除した場合などにおいて、切断された神経の両端部のそれぞれを縫合可能な長さにまで緩徐的に伸長した後、両断端を縫合する手術を行うために利用する神経伸長器具に関する。   The present invention provides a length capable of suturing both ends of a cut nerve when a nerve defect gap that cannot be directly sutured due to trauma or the like occurs, or when a nerve is also removed when excising a tumor or the like. The present invention relates to a nerve stretching instrument that is used for performing an operation for suturing both stumps after slowly stretching to a certain extent.

現在、末梢神経などの欠損間隙の治療には、欠損部分にドナー神経を配し、切断された神経の両断端のそれぞれをドナー神経と縫合する遊離神経移植術が主として採用されている。しかしながら、この方法は、ドナー神経を摘出した部位に神経欠落症状などを引き起こす場合があることや、縫合部が2箇所必要になるので、縫合部を再生軸索が超える際に神経再生過誤(misdirection)の頻度が増し、欠損長が長い場合には良好な再生が困難であるといった問題を有している。そこで、このような問題を回避するための新たな治療方法の開発が進められており、その一つとして、切断された神経の両端部のそれぞれを縫合可能な長さにまで緩徐的に伸長した後、両断端を縫合する手術を行う方法が提案されている(非特許文献1)。
Saijilafu et al. : Repair of peripheral nerve defect with direct gradual lengthening of the proximal nerve stump in rats. : Journal of Orthopaedic Research, Volume 24, Issue 12, December 2006, 2246-2253.
At present, for the treatment of defect gaps such as peripheral nerves, free nerve transplantation is mainly employed in which donor nerves are arranged in the defect part and both cut ends of the cut nerves are sutured to the donor nerves. However, this method may cause a nerve deficiency symptom at the site where the donor nerve is removed, and two suture parts are required. Therefore, when the regeneration axon crosses the suture part, a nerve regeneration error (misdirection) ) And the length of the defect is long, it is difficult to perform good reproduction. Therefore, development of a new treatment method for avoiding such a problem has been promoted, and as one of them, each of both ends of the cut nerve is slowly extended to a suturable length. Thereafter, a method of performing an operation for suturing both stumps has been proposed (Non-Patent Document 1).
Saijilafu et al .: Repair of peripheral nerve defect with direct gradual lengthening of the proximal nerve stump in rats .: Journal of Orthopedic Research, Volume 24, Issue 12, December 2006, 2246-2253.

本発明は、切断された神経の両端部のそれぞれを縫合可能な長さにまで緩徐的に伸長するための神経伸長器具を提供することを目的とする。   An object of the present invention is to provide a nerve stretching instrument for slowly stretching each of both ends of a cut nerve to a length capable of suturing.

上記の点に鑑みてなされた本発明の神経伸長器具は、切断された神経の両端部のそれぞれを牽引して伸長するための器具である。この器具は、棒状部材が、骨に挿入する少なくとも2本のピンを保持する保持部材を中央部付近に備え、保持部材の両側に棒状部材の端部方向に移動可能な移動部材を備えている。また、棒状部材は、保持部材と移動部材の間に糸状部材をガイドするガイド部材を備えている。一方の末端が神経の端部を把持する把持部材に固定された糸状部材は、このガイド部材を通り、他方の末端が移動部材に固定されている。かかる構成により、移動部材を棒状部材の端部方向に移動させることで、切断された神経の端部を糸状部材で牽引して伸長することができる。   The nerve extending instrument of the present invention made in view of the above points is an instrument for pulling and extending each end of a cut nerve. In this instrument, the rod-shaped member includes a holding member that holds at least two pins to be inserted into the bone in the vicinity of the central portion, and includes movable members that can move in the direction of the end of the rod-shaped member on both sides of the holding member. . Further, the bar-like member includes a guide member that guides the thread-like member between the holding member and the moving member. The filamentary member fixed at one end to the gripping member that holds the end of the nerve passes through the guide member, and the other end is fixed to the moving member. With this configuration, by moving the moving member in the direction of the end of the rod-shaped member, the end of the cut nerve can be pulled and extended by the thread-like member.

本発明の神経伸長器具によれば、移動部材の棒状部材の端部方向への移動の程度を自由に調節することができるので、例えば1日1mm移動させることで、切断された神経の端部を糸状部材で牽引して1日1mm緩徐的に伸長することができる。よって、切断された神経の伸長を患者の年齢や患部の状態などに応じて適切に行うことができる。また、左右それぞれの移動部材の移動の程度を異ならせれば、切断された神経の端部のそれぞれの伸長の程度を異ならせることもできる。   According to the nerve stretching instrument of the present invention, the degree of movement of the moving member in the direction of the end of the rod-shaped member can be freely adjusted. For example, by moving 1 mm per day, the end of the cut nerve Can be slowly extended by 1 mm per day by pulling with a thread-like member. Therefore, it is possible to appropriately extend the cut nerve according to the age of the patient, the state of the affected part, and the like. Further, if the degree of movement of the left and right moving members is made different, the degree of extension of each end portion of the cut nerve can be made different.

(a)は本発明の神経伸長器具の一実施形態の概略構成を示す正面図(一部透視図)であり、(b)は、平面図(一部透視図)である。(A) is a front view (partially perspective view) showing a schematic configuration of an embodiment of the nerve extending instrument of the present invention, and (b) is a plan view (partially perspective view). 本発明の神経伸長器具の一実施形態の使用状態を示す図である。It is a figure which shows the use condition of one Embodiment of the nerve extending | stretching instrument of this invention. 切断された神経の端部と神経把持リング6の縫い付け形態の一例である。It is an example of the sewing form of the edge part of the cut | disconnected nerve and the nerve grasping ring 6. FIG.

1 神経伸長器具
2 棒状部材
2a 軸ネジ
2b 内筒
2c 外筒
3 ピン
4 保持部材
5 移動部材
6 神経把持リング(把持部材)
7 糸状部材
8 ガイド部材
9 六角孔
10 挟着ネジ
11 挟着ネジ
12 挟着ネジ
13 筒部材
14 挟着ネジ
15 挟着ネジ
DESCRIPTION OF SYMBOLS 1 Nerve extension instrument 2 Rod-shaped member 2a Shaft screw 2b Inner cylinder 2c Outer cylinder 3 Pin 4 Holding member 5 Moving member 6 Nerve grasping ring (gripping member)
7 Threaded member 8 Guide member 9 Hexagonal hole 10 Clamping screw 11 Clamping screw 12 Clamping screw 13 Cylinder member 14 Clamping screw 15 Clamping screw

本発明の神経伸長器具は、切断された神経の両端部のそれぞれを牽引して伸長するための器具であって、棒状部材に対し、骨に挿入する少なくとも2本のピンを保持する保持部材を中央部付近に備え、保持部材の両側に棒状部材の端部方向に移動可能な移動部材を備え、さらに、一方の末端が移動部材に固定され、他方の末端が神経の端部を把持する把持部材に固定された糸状部材をガイドするガイド部材を保持部材と移動部材の間に備え、移動部材を棒状部材の端部方向に移動させることで、切断された神経の端部を糸状部材で牽引して伸長することができるようにしたことを特徴とするものである。以下、本発明の神経伸長器具を図面に基づいて説明するが、本発明の神経伸長器具は以下の記載に限定して解釈されるものではない。   The nerve extending instrument of the present invention is an instrument for pulling and extending each of both ends of a cut nerve, and a holding member that holds at least two pins to be inserted into a bone with respect to a rod-shaped member A gripping member is provided near the center, and has a movable member that can move in the direction of the end of the rod-shaped member on both sides of the holding member. Further, one end is fixed to the moving member and the other end grips the end of the nerve. A guide member that guides the thread-like member fixed to the member is provided between the holding member and the moving member, and the end of the cut nerve is pulled by the thread-like member by moving the moving member toward the end of the rod-like member. Thus, it can be extended. Hereinafter, although the nerve extending | stretching instrument of this invention is demonstrated based on drawing, the nerve extending | stretching instrument of this invention is limited to the following description, and is not interpreted.

図1(a)は、本発明の神経伸長器具の一実施形態の概略構成を示す正面図(一部透視図)であり、同(b)は、平面図(一部透視図)である。この神経伸長器具1は、中心部の棒状部材2が、骨に挿入する2本のピン3を保持する保持部材4を中央部に備え、保持部材4の両側に棒状部材2の端部方向に移動可能な移動部材5を備えている。また、棒状部材2は、保持部材4の両脇に糸状部材7をガイドするガイド部材8を備えている。一方の末端が神経の端部を把持する把持部材としての神経把持リング6に固定された糸状部材7は、このガイド部材8を通り、他方の末端が移動部材5に固定されている。棒状部材2、ピン3、保持部材4、移動部材5、ガイド部材8の材質は、例えばステンレス製であり、神経把持リング6の材質は、例えばポリエチレン製であり、糸状部材7の材質は、例えばナイロン製である。   Fig.1 (a) is a front view (partially see-through | perspective view) which shows schematic structure of one Embodiment of the nerve extending | stretching instrument of this invention, The same (b) is a top view (partially see-through view). In this nerve extending instrument 1, a central rod-shaped member 2 includes a central holding member 4 that holds two pins 3 to be inserted into a bone, and both ends of the holding member 4 in the direction of the end of the rod-shaped member 2. A movable moving member 5 is provided. The rod-shaped member 2 includes guide members 8 that guide the thread-shaped member 7 on both sides of the holding member 4. The thread-like member 7 fixed to the nerve gripping ring 6 as a gripping member whose one end grips the end of the nerve passes through the guide member 8, and the other end is fixed to the moving member 5. The rod-shaped member 2, the pin 3, the holding member 4, the moving member 5, and the guide member 8 are made of, for example, stainless steel, the nerve gripping ring 6 is made of, for example, polyethylene, and the thread-like member 7 is made of, for example, Made of nylon.

棒状部材2のガイド部材8より端部側の部分は、端面に六角孔9が設けられた軸ネジ2aと、軸ネジ2aに螺合するネジ溝が内径面に刻まれた内筒2bと、内筒2bと嵌合する外筒2cとからなり、軸ネジ2aの端面に設けられた六角孔9にレンチを挿入して軸ネジ2aをその軸線を中心に回転させることで、外筒2cが内筒2bに対してスライドして端部方向に移動することにより、外筒2cに挟着ネジ10によって固定された移動部材5も端部方向に移動する仕組みとなっている。   The portion of the rod-like member 2 on the end side from the guide member 8 includes a shaft screw 2a having a hexagonal hole 9 provided on the end surface, an inner cylinder 2b in which a thread groove that engages with the shaft screw 2a is carved on the inner diameter surface, The outer cylinder 2c is fitted with the inner cylinder 2b. A wrench is inserted into the hexagonal hole 9 provided on the end face of the shaft screw 2a, and the shaft screw 2a is rotated about its axis, whereby the outer cylinder 2c is The moving member 5 fixed to the outer cylinder 2c with the clamping screw 10 is also moved in the end direction by sliding with respect to the inner cylinder 2b and moving in the end direction.

ピン3は、上下に可動自在であり、挟着ネジ11によって骨に挿入しやすい高さで保持部材4に固定される。   The pin 3 is movable up and down, and is fixed to the holding member 4 at a height that can be easily inserted into the bone by a clamping screw 11.

また、保持部材4は、棒状部材2の軸線を中心に回転自在であり、挟着ネジ12によってピン3を骨に挿入しやすい回転角度で棒状部材2に固定される。   The holding member 4 is rotatable about the axis of the rod-shaped member 2 and is fixed to the rod-shaped member 2 at a rotation angle at which the pin 3 can be easily inserted into the bone by the clamping screw 12.

ガイド部材8には、切断された神経の端部を糸状部材7で牽引しやすくするための筒部材13が挟着ネジ14によって固定されており、糸状部材7は、ガイド部材8に固定された筒部材13を通り、一方の末端が移動部材5に固定され、他方の末端が神経把持リング6に固定されている。筒部材13は、その機能を最大限に発揮させるために、体内に挿入される側の端部が湾曲せしめられ、また、所定の高さでガイド部材8に固定される。ガイド部材8は、棒状部材2の軸線を中心に回転自在であり、挟着ネジ15によって切断された神経の端部を糸状部材7で牽引しやすい回転角度で棒状部材2に固定される。   A cylindrical member 13 for facilitating the pulling of the end of the cut nerve by the thread-like member 7 is fixed to the guide member 8 by a clamping screw 14. The thread-like member 7 is fixed to the guide member 8. One end is fixed to the moving member 5 through the cylindrical member 13, and the other end is fixed to the nerve grasping ring 6. In order to maximize the function of the cylindrical member 13, the end portion on the side inserted into the body is curved, and is fixed to the guide member 8 at a predetermined height. The guide member 8 is rotatable about the axis of the rod-shaped member 2, and is fixed to the rod-shaped member 2 at a rotation angle at which the end of the nerve cut by the clamping screw 15 is easily pulled by the thread-shaped member 7.

図2に示すように、2本のピン3を骨に挿入して神経伸長器具1を固定し、切断された神経の端部と神経把持リング6を縫い付け、手術部位を縫合した後(この処置によって体内に埋入されるのは2本のピン3の一部、筒部材13の一部、神経把持リング6、糸状部材7の一部である)、軸ネジ2aの端面に設けられた六角孔9にレンチを挿入し、軸ネジ2aをその軸線を中心に回転させると、外筒2cが棒状部材2の端部方向に移動することで、外筒2cに固定された移動部材5も棒状部材2の端部方向に移動し、これにより、切断された神経の端部を糸状部材7で牽引して伸長することができる。例えば軸ネジ2aをその軸線を中心に1回転させる毎に外筒2cが0.5mm移動するように軸ネジ2aのネジ切りを行い、例えば1日2回、朝と夕に1回転ずつ軸ネジ2aを回転させ、移動部材5を棒状部材2の端部方向に1日で都合1mm移動させることで、切断された神経の端部を糸状部材7で牽引して1日1mm緩徐的に伸長することができる。また、左右それぞれの軸ネジ2aを異なった回転数で回転させれば、切断された神経の端部のそれぞれの伸長の程度を異ならせることもできる。   As shown in FIG. 2, after inserting the two pins 3 into the bone to fix the nerve extension device 1, the end of the cut nerve and the nerve grasping ring 6 are sewn, and the surgical site is sutured (this The part embedded in the body by the treatment is a part of the two pins 3, a part of the cylindrical member 13, a part of the nerve grasping ring 6 and the thread-like member 7), and provided on the end face of the shaft screw 2 a. When a wrench is inserted into the hexagonal hole 9 and the shaft screw 2a is rotated about its axis, the outer cylinder 2c moves in the direction of the end of the rod-shaped member 2, so that the moving member 5 fixed to the outer cylinder 2c is also It moves in the direction of the end of the rod-like member 2, whereby the end of the cut nerve can be pulled and extended by the thread-like member 7. For example, every time the shaft screw 2a is rotated about its axis, the shaft screw 2a is threaded so that the outer cylinder 2c moves 0.5 mm. For example, the shaft screw 2 turns once a day in the morning and evening. By rotating 2a and moving the moving member 5 in the direction of the end of the rod-shaped member 2 by 1 mm for one day, the end of the cut nerve is pulled by the thread-like member 7 and slowly extended by 1 mm per day. be able to. Further, if the left and right shaft screws 2a are rotated at different rotational speeds, the degree of extension of the cut nerve ends can be varied.

なお、神経把持リング6の側面に、切断された神経の端部と神経把持リング6を縫い付けるための縫合糸を通す孔を複数個設けておくことで(孔は直線状の縫合針を一方の側面から対向する側面に貫通させることができるように配置されていることが望ましい)、例えば図3に示すようにして両者を縫い付けることが可能となり、切断された神経の端部を糸状部材7で確実に牽引して伸長することができる。   By providing a plurality of holes on the side of the nerve grasping ring 6 for passing the end of the cut nerve and the suture thread for sewing the nerve grasping ring 6 (one hole is a straight suture needle). For example, as shown in FIG. 3, it is possible to sew both together, and the end of the cut nerve is a thread-like member. 7 can be reliably pulled and extended.

本発明は、切断された神経の両端部のそれぞれを縫合可能な長さにまで緩徐的に伸長するための神経伸長器具を提供することができる点において産業上の利用可能性を有する。   INDUSTRIAL APPLICABILITY The present invention has industrial applicability in that it can provide a nerve extension device for slowly extending each of both ends of a cut nerve to a suturable length.

Claims (1)

切断された神経の両端部のそれぞれを牽引して伸長するための器具であって、棒状部材に対し、骨に挿入する少なくとも2本のピンを保持する保持部材を中央部付近に備え、保持部材の両側に棒状部材の端部方向に移動可能な移動部材を備え、さらに、一方の末端が移動部材に固定され、他方の末端が神経の端部を把持する把持部材に固定された糸状部材をガイドするガイド部材を保持部材と移動部材の間に備え、移動部材を棒状部材の端部方向に移動させることで、切断された神経の端部を糸状部材で牽引して伸長することができるようにしたことを特徴とする神経伸長器具。   An instrument for pulling and extending each of both ends of a cut nerve, comprising a holding member for holding at least two pins to be inserted into a bone in the vicinity of the central portion of the rod-like member, the holding member A thread-like member fixed to a gripping member that has one end fixed to the moving member and the other end gripping the end of the nerve. A guide member for guiding is provided between the holding member and the moving member, and by moving the moving member in the direction of the end of the rod-like member, the end of the cut nerve can be pulled and extended by the thread-like member. A nerve extension device characterized by being made.
JP2010514455A 2008-05-27 2009-05-22 Nerve extension device Withdrawn JPWO2009145116A1 (en)

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JP2008138590 2008-05-27
JP2008138590 2008-05-27
PCT/JP2009/059417 WO2009145116A1 (en) 2008-05-27 2009-05-22 Nerve elongation apparatus

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CN110115616B (en) * 2018-02-05 2023-12-15 复旦大学附属华山医院 Subcutaneous nerve free cutter
WO2023004814A1 (en) * 2021-07-30 2023-02-02 中国人民解放军总医院第一医学中心 In vivo microrobot for nerve traction

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US4936843A (en) * 1989-02-16 1990-06-26 Ace Orthopedic Manufacturing Kirschner wire clamp and tensioner
US5163948A (en) * 1991-05-02 1992-11-17 Hospital For Joint Diseases Nerve tissue repair apparatus and method
US6045572A (en) * 1998-10-16 2000-04-04 Cardiac Assist Technologies, Inc. System, method and apparatus for sternal closure

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