JPS6485972A - Carcinostatic agent and production thereof - Google Patents

Carcinostatic agent and production thereof

Info

Publication number
JPS6485972A
JPS6485972A JP10679087A JP10679087A JPS6485972A JP S6485972 A JPS6485972 A JP S6485972A JP 10679087 A JP10679087 A JP 10679087A JP 10679087 A JP10679087 A JP 10679087A JP S6485972 A JPS6485972 A JP S6485972A
Authority
JP
Japan
Prior art keywords
derivative
sesquiterpenelactone
belonging
named
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10679087A
Other languages
Japanese (ja)
Inventor
Nobuo Ikegawa
Yoshinori Fujimoto
Tetsuo Ikegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP10679087A priority Critical patent/JPS6485972A/en
Publication of JPS6485972A publication Critical patent/JPS6485972A/en
Pending legal-status Critical Current

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  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A sesquiterpenelactone derivative shown by the formula [R1 is H or OR' (R' is H, alkyl or acryl); R2 and R3 are CH2= or R2 is H and R3 is -CH2 or OR']. EXAMPLE:Guternbergin. USE:A drug. An active ingredient for carcinostatic agent. The derivative is an eudesmanolinde-based compound, has low side effects and shows strongly carcinostatic activity. Especially a new sesquiterpenelactone derivative named gutenbergin belonging to eudesmanolide shows strong cytotoxicity on leukemia and is expected to the effective against adult T-cell leukemia and AIDS, diseases based on HTLV. PREPARATION:Leaves of higher plant Gutenbergia Cordifilia named idoma, belonging to the family Compositae are extracted with an organic solvent such as chloroform, fractionated by column chromatography using silica gel, separated and purified to give a compound shown by the formula.
JP10679087A 1987-04-30 1987-04-30 Carcinostatic agent and production thereof Pending JPS6485972A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10679087A JPS6485972A (en) 1987-04-30 1987-04-30 Carcinostatic agent and production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10679087A JPS6485972A (en) 1987-04-30 1987-04-30 Carcinostatic agent and production thereof

Publications (1)

Publication Number Publication Date
JPS6485972A true JPS6485972A (en) 1989-03-30

Family

ID=14442690

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10679087A Pending JPS6485972A (en) 1987-04-30 1987-04-30 Carcinostatic agent and production thereof

Country Status (1)

Country Link
JP (1) JPS6485972A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225032A (en) * 1991-08-09 1993-07-06 Allied-Signal Inc. Method of producing stoichiometric, epitaxial, monocrystalline films of silicon carbide at temperatures below 900 degrees centigrade

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225032A (en) * 1991-08-09 1993-07-06 Allied-Signal Inc. Method of producing stoichiometric, epitaxial, monocrystalline films of silicon carbide at temperatures below 900 degrees centigrade

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