JPS6475488A - Production of beta-lactam compound - Google Patents

Production of beta-lactam compound

Info

Publication number
JPS6475488A
JPS6475488A JP62233260A JP23326087A JPS6475488A JP S6475488 A JPS6475488 A JP S6475488A JP 62233260 A JP62233260 A JP 62233260A JP 23326087 A JP23326087 A JP 23326087A JP S6475488 A JPS6475488 A JP S6475488A
Authority
JP
Japan
Prior art keywords
formula
compound
beta
production
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62233260A
Other languages
Japanese (ja)
Inventor
Jun Sunakawa
Yutaka Takeuchi
Yutaka Kitamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharmaceuticals Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Priority to JP62233260A priority Critical patent/JPS6475488A/en
Publication of JPS6475488A publication Critical patent/JPS6475488A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

PURPOSE:To obtain the titled compound useful as an antimicrobial agent at low cost, by deprotecting a specific compound in an inert solvent in the presence of a nickel complex and a reaction auxiliary. CONSTITUTION:A compound shown by formula I [R1 is H or OH-protecting group; R2 is (substituted)2-alkenyl; X is S or group shown by formula II (R3 is H or alkyl); Y is H or group shown by formula III (R4 and R5 are H, alkyl or R4 and R5 are bonded to form ethylene or propylene chain; n is 0-4)] is deprotected in an inert solvent (e.g. diethyl ether or benzene) in the presence of a nickel complex and a reaction auxiliary preferably at 10-50 deg.C to give the aimed compound shown by formula IV (R1' is H or OH-protecting group).
JP62233260A 1987-09-17 1987-09-17 Production of beta-lactam compound Pending JPS6475488A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62233260A JPS6475488A (en) 1987-09-17 1987-09-17 Production of beta-lactam compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62233260A JPS6475488A (en) 1987-09-17 1987-09-17 Production of beta-lactam compound

Publications (1)

Publication Number Publication Date
JPS6475488A true JPS6475488A (en) 1989-03-22

Family

ID=16952290

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62233260A Pending JPS6475488A (en) 1987-09-17 1987-09-17 Production of beta-lactam compound

Country Status (1)

Country Link
JP (1) JPS6475488A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071330B2 (en) * 2001-01-16 2006-07-04 Williams John M Process for carbapenem synthesis
CN101962383A (en) * 2010-11-12 2011-02-02 上海巴迪生物医药科技有限公司 Synthesis method of meropenem

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071330B2 (en) * 2001-01-16 2006-07-04 Williams John M Process for carbapenem synthesis
CN101962383A (en) * 2010-11-12 2011-02-02 上海巴迪生物医药科技有限公司 Synthesis method of meropenem

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