JPS6475468A - Production of 2,3,5-trichloropyridine - Google Patents

Production of 2,3,5-trichloropyridine

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Publication number
JPS6475468A
JPS6475468A JP23148887A JP23148887A JPS6475468A JP S6475468 A JPS6475468 A JP S6475468A JP 23148887 A JP23148887 A JP 23148887A JP 23148887 A JP23148887 A JP 23148887A JP S6475468 A JPS6475468 A JP S6475468A
Authority
JP
Japan
Prior art keywords
formula
compound shown
give
compound
butoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP23148887A
Other languages
Japanese (ja)
Other versions
JPH0822851B2 (en
Inventor
Masayuki Umeno
Satoshi Takita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hokko Chemical Industry Co Ltd
Original Assignee
Hokko Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokko Chemical Industry Co Ltd filed Critical Hokko Chemical Industry Co Ltd
Priority to JP23148887A priority Critical patent/JPH0822851B2/en
Publication of JPS6475468A publication Critical patent/JPS6475468A/en
Publication of JPH0822851B2 publication Critical patent/JPH0822851B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Pyridine Compounds (AREA)

Abstract

PURPOSE:To obtain the titled compound useful as an intermediate in the field of agricultural chemical, drug and dye in high yield and in high purity, by converting 2-chloropyridine as a starting raw material through 2-n-butoxypyridine to 2- hydroxypyridine and chlorinating 2-hydroxypyridine at two stages. CONSTITUTION:n-Butanol is heated in metal sodium to form sodium n-butoxide, a compound shown by formula I is gradually dripped into a solution of n-butoxide, reacted with n-butoxide at reflux temperature to give a compound shown by formula II, into which a chlorine gas is introduced, the compound is converted into a hydrochloride and subjected to thermal decomposition reaction to give a compound shown by formula IV. DMF as a solvent is added to the compound shown by formula IV, which is chlorinated at 10-20 deg.C with a chlorine gas in an amount required to give chlorine 1.0-1.05 as much as the theoretical amount to convert the whole compound into 3.5-dichloro compound shown by formula V. Then DMF is distilled away, the resultant substance is incorporated with a high-boiling aromatic solvent, chlorinated with a chlorinating agent (e.g. thionyl chloride or phosphorus trioxide) in an amount to give 1.2-1.5 as much as theoretical amount and the aimed compound shown by formula VI is obtained.
JP23148887A 1987-09-16 1987-09-16 Method for producing 2,3,5-trichloropyridine Expired - Lifetime JPH0822851B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP23148887A JPH0822851B2 (en) 1987-09-16 1987-09-16 Method for producing 2,3,5-trichloropyridine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23148887A JPH0822851B2 (en) 1987-09-16 1987-09-16 Method for producing 2,3,5-trichloropyridine

Publications (2)

Publication Number Publication Date
JPS6475468A true JPS6475468A (en) 1989-03-22
JPH0822851B2 JPH0822851B2 (en) 1996-03-06

Family

ID=16924276

Family Applications (1)

Application Number Title Priority Date Filing Date
JP23148887A Expired - Lifetime JPH0822851B2 (en) 1987-09-16 1987-09-16 Method for producing 2,3,5-trichloropyridine

Country Status (1)

Country Link
JP (1) JPH0822851B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0591624A1 (en) * 1992-10-07 1994-04-13 Rütgerswerke Aktiengesellschaft Process for the preparation of pure 2,5-dichloropyridine and the isolation of 2,3-dichloropyridine which is formed as a by-product
US5973159A (en) * 1997-03-07 1999-10-26 Zeneca Limited Chemical process
US6143899A (en) * 1998-09-03 2000-11-07 Zeneca Limited Chemical process
CN104478793A (en) * 2014-11-20 2015-04-01 盐城恒盛化工有限公司 Synthetic method of 2, 3, 5-trichloropyridine
CN105503707A (en) * 2016-01-22 2016-04-20 江苏丰山集团股份有限公司 Preparation method of 2, 3, 5-trichloropyridine

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102643227A (en) * 2011-02-16 2012-08-22 山东谦诚工贸科技有限公司 Method for synthesizing 3,5,6-trichloro-2-pyridol by chlorination of 6-chloro-2-hydroxypyridine sodium salt

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0591624A1 (en) * 1992-10-07 1994-04-13 Rütgerswerke Aktiengesellschaft Process for the preparation of pure 2,5-dichloropyridine and the isolation of 2,3-dichloropyridine which is formed as a by-product
US5973159A (en) * 1997-03-07 1999-10-26 Zeneca Limited Chemical process
US6143899A (en) * 1998-09-03 2000-11-07 Zeneca Limited Chemical process
CN104478793A (en) * 2014-11-20 2015-04-01 盐城恒盛化工有限公司 Synthetic method of 2, 3, 5-trichloropyridine
CN105503707A (en) * 2016-01-22 2016-04-20 江苏丰山集团股份有限公司 Preparation method of 2, 3, 5-trichloropyridine

Also Published As

Publication number Publication date
JPH0822851B2 (en) 1996-03-06

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