JPS6463862A - High sensitivity immunoassay using nad synthetic enzyme - Google Patents
High sensitivity immunoassay using nad synthetic enzymeInfo
- Publication number
- JPS6463862A JPS6463862A JP22082087A JP22082087A JPS6463862A JP S6463862 A JPS6463862 A JP S6463862A JP 22082087 A JP22082087 A JP 22082087A JP 22082087 A JP22082087 A JP 22082087A JP S6463862 A JPS6463862 A JP S6463862A
- Authority
- JP
- Japan
- Prior art keywords
- nad
- synthetic enzyme
- antibody
- antigen
- high sensitivity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
PURPOSE:To enhance the sensitivity of immunoassay, by using a conjugate wherein NAD synthetic enzyme is bonded to an antibody or antigen. CONSTITUTION:The NAD synthetic enzyme derived from Bacillus stearothermophylus is bonded to an antibody or antigen directly or a chemical means using a crosslinking agent. The obtained conjugated is immunologically reacted with an antigen or antibody, and ATP, deamino-NAD and an ammonium ion are allowed to act on NAD synthetic enzyme being at least one of the immune conjugate and immunologically unreacted conjugate generated by said immunoreaction to measure at least one component of NAD, AMP and ppi formed by the NAD synthetic enzyme.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22082087A JPS6463862A (en) | 1987-09-03 | 1987-09-03 | High sensitivity immunoassay using nad synthetic enzyme |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22082087A JPS6463862A (en) | 1987-09-03 | 1987-09-03 | High sensitivity immunoassay using nad synthetic enzyme |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6463862A true JPS6463862A (en) | 1989-03-09 |
Family
ID=16757065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP22082087A Pending JPS6463862A (en) | 1987-09-03 | 1987-09-03 | High sensitivity immunoassay using nad synthetic enzyme |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6463862A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006093224A1 (en) * | 2005-03-03 | 2006-09-08 | Daiichi Pure Chemicals Co., Ltd. | Immunoassay method and reagent therefor |
-
1987
- 1987-09-03 JP JP22082087A patent/JPS6463862A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006093224A1 (en) * | 2005-03-03 | 2006-09-08 | Daiichi Pure Chemicals Co., Ltd. | Immunoassay method and reagent therefor |
US7759072B2 (en) | 2005-03-03 | 2010-07-20 | Sekisui Medical Co., Ltd. | Immunoassay method and reagent therefor |
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