JPS6461481A - Porphyrin derivative - Google Patents
Porphyrin derivativeInfo
- Publication number
- JPS6461481A JPS6461481A JP62216534A JP21653487A JPS6461481A JP S6461481 A JPS6461481 A JP S6461481A JP 62216534 A JP62216534 A JP 62216534A JP 21653487 A JP21653487 A JP 21653487A JP S6461481 A JPS6461481 A JP S6461481A
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- iodine
- gamma
- cancer
- dotted line
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound expressed by the formula [R1 and R2 represent -CH=CH2, -CH2CH3, etc.; R3 represents H, COOH, -COR (R represents OH or residue formed by eliminating H from an amino-acid), etc.; R4 represents OH or R; A represents CH2- or -CO-; dotted line bonded to the gamma-position represents no-binding or single bond; dotted line between the gamma-position and the 8-position represents single bond or double bond] and metal complex thereof (provided that the metal complex is in a porphyrin skeleton, and at least one of R3 and R4 represents group having R which represents tyrosine, fluorine- containing amino acid or iodine-containing amino acid residue). EXAMPLE:2,4-Bis[1-(2-hydroxyethyloxy)ethyl]-Ga-deuteroporphyrinyl dityrosine. USE:A cancer-directing medical preparation used for treatment, diagnosis, marker and misile-targeting therapeia of cancer. PREPARATION:A porphyrin compound corresponding to the formula wherein R is OH is formed and an amino acid residue is introduced thereto. Iodine, as necessary, is bonded.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62216534A JPS6461481A (en) | 1987-09-01 | 1987-09-01 | Porphyrin derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62216534A JPS6461481A (en) | 1987-09-01 | 1987-09-01 | Porphyrin derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6461481A true JPS6461481A (en) | 1989-03-08 |
Family
ID=16689943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62216534A Pending JPS6461481A (en) | 1987-09-01 | 1987-09-01 | Porphyrin derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6461481A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5492924A (en) * | 1993-09-24 | 1996-02-20 | Fox Chase Cancer Center | Phorbine derivatives and their use in the diagnosis and therapy of cancer |
KR100484206B1 (en) * | 2003-01-16 | 2005-04-20 | 주식회사 테크노마트 | Porphyrin derivatives |
-
1987
- 1987-09-01 JP JP62216534A patent/JPS6461481A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5492924A (en) * | 1993-09-24 | 1996-02-20 | Fox Chase Cancer Center | Phorbine derivatives and their use in the diagnosis and therapy of cancer |
KR100484206B1 (en) * | 2003-01-16 | 2005-04-20 | 주식회사 테크노마트 | Porphyrin derivatives |
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