JPS6442488A - Production of 7-acylaminodeacetoxycephalosporanic acid or ester thereof - Google Patents

Production of 7-acylaminodeacetoxycephalosporanic acid or ester thereof

Info

Publication number
JPS6442488A
JPS6442488A JP20039887A JP20039887A JPS6442488A JP S6442488 A JPS6442488 A JP S6442488A JP 20039887 A JP20039887 A JP 20039887A JP 20039887 A JP20039887 A JP 20039887A JP S6442488 A JPS6442488 A JP S6442488A
Authority
JP
Japan
Prior art keywords
acid
coor
formula
nitrogen atom
butyl acetate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP20039887A
Other languages
Japanese (ja)
Inventor
Shinji Oshita
Aiichiro Kiyama
Mitsuo Kishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP20039887A priority Critical patent/JPS6442488A/en
Publication of JPS6442488A publication Critical patent/JPS6442488A/en
Pending legal-status Critical Current

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  • Cephalosporin Compounds (AREA)

Abstract

PURPOSE:To industrially and advantageously obtain the titled compound useful as a starting raw material for an intermediate of an antibacterial agent, by heating esters of an acylamidopenicillanic acid sulfoxide in butyl acetate in the presence of a base containing both acid and nitrogen atom. CONSTITUTION:Esters (example; 2,2,2-trichloroethyl 6-phenylacetamidopenici llanate) of a 6-acylamidopenicillanic acid sulfoxide expressed by formula I (R<1> represents phenylacetyl or phenoxyacetyl; -COOR<2> represents esterified carboxyl) are heated in butyl acetate in the presence of a base containing both acid and nitrogen atom (example. pyridine trichloroethylphosphate) up to 130 deg.C at the highest, and, as necessary, followed by esterification to afford the aimed compound expressed by formula II (COOR represents carboxyl or esterified carboxyl).
JP20039887A 1987-08-11 1987-08-11 Production of 7-acylaminodeacetoxycephalosporanic acid or ester thereof Pending JPS6442488A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP20039887A JPS6442488A (en) 1987-08-11 1987-08-11 Production of 7-acylaminodeacetoxycephalosporanic acid or ester thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20039887A JPS6442488A (en) 1987-08-11 1987-08-11 Production of 7-acylaminodeacetoxycephalosporanic acid or ester thereof

Publications (1)

Publication Number Publication Date
JPS6442488A true JPS6442488A (en) 1989-02-14

Family

ID=16423658

Family Applications (1)

Application Number Title Priority Date Filing Date
JP20039887A Pending JPS6442488A (en) 1987-08-11 1987-08-11 Production of 7-acylaminodeacetoxycephalosporanic acid or ester thereof

Country Status (1)

Country Link
JP (1) JPS6442488A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102584853A (en) * 2011-12-14 2012-07-18 伊犁川宁生物技术有限公司 Preparation method of 7-aminodeacetoxy cephalosporanic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102584853A (en) * 2011-12-14 2012-07-18 伊犁川宁生物技术有限公司 Preparation method of 7-aminodeacetoxy cephalosporanic acid

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