JPS6439992A - Monoclonal antibody - Google Patents
Monoclonal antibodyInfo
- Publication number
- JPS6439992A JPS6439992A JP62195809A JP19580987A JPS6439992A JP S6439992 A JPS6439992 A JP S6439992A JP 62195809 A JP62195809 A JP 62195809A JP 19580987 A JP19580987 A JP 19580987A JP S6439992 A JPS6439992 A JP S6439992A
- Authority
- JP
- Japan
- Prior art keywords
- monoclonal antibody
- cell
- give
- fused
- mouse
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PURPOSE:To obtain a monoclonal antibody to be specifically reacted with human osteosarcoma useful with respect to medicine and clinical diagnosis, by cloning an immunocyte of mouse. CONSTITUTION:An animal such as mouse is immunized against an antigen (e.g. isolated antigen, antigen-containing tumor cell or homogenate thereof) to be recognized by a monoclonal antibody and an antibody-forming cell is obtained from an immunized animal. Then the cell is fused with a myeloma cell to give a fused cell, which is screened to give a fused cell to produce a monoclonal antibody. Then the fused cell is cloned and cultivated in a medium to give a supernatant liquid of the culture. The supernatant liquid is separated and purified to give a monoclonal antibody such as mouse monoclonal antibody 2H10 or 2D3 to be specifically reacted with human osteosarcoma.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62195809A JPS6439992A (en) | 1987-08-05 | 1987-08-05 | Monoclonal antibody |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62195809A JPS6439992A (en) | 1987-08-05 | 1987-08-05 | Monoclonal antibody |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6439992A true JPS6439992A (en) | 1989-02-10 |
Family
ID=16347344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62195809A Pending JPS6439992A (en) | 1987-08-05 | 1987-08-05 | Monoclonal antibody |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6439992A (en) |
-
1987
- 1987-08-05 JP JP62195809A patent/JPS6439992A/en active Pending
Non-Patent Citations (7)
Title |
---|
BRITISH JOURNAL OF CANCER=1981 * |
CANCER RESERCH 42=1982 * |
CANCER RESERCH 44=1984 * |
CANCER RESERCH 46=1986 * |
EUROPEAN JOURNAL OF CANCER&CLINICAL ONCOLOGY=1983 * |
JOURNAL OF THE NATIONAL CANCER INSTITUTE=1986 * |
PROC.JPN.CANCER ASSOC.45=1986 * |
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