JPS6425720A - Percutaneous absorption pharmaceutical - Google Patents

Percutaneous absorption pharmaceutical

Info

Publication number
JPS6425720A
JPS6425720A JP8108388A JP8108388A JPS6425720A JP S6425720 A JPS6425720 A JP S6425720A JP 8108388 A JP8108388 A JP 8108388A JP 8108388 A JP8108388 A JP 8108388A JP S6425720 A JPS6425720 A JP S6425720A
Authority
JP
Japan
Prior art keywords
fatty acid
percutaneous absorption
absorption pharmaceutical
acylsarcosine
absorbefacient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8108388A
Other languages
Japanese (ja)
Inventor
Masato Azuma
Toshihiro Inoue
Yasuaki Kawano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Sekisui Chemical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Sekisui Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Sekisui Chemical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP8108388A priority Critical patent/JPS6425720A/en
Publication of JPS6425720A publication Critical patent/JPS6425720A/en
Pending legal-status Critical Current

Links

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE:To obtain a percutaneous absorption pharmaceutical, by using a specific absorbefacient consisting of combination of a fatty acid ester with a specific N-acylsarcosine, etc., and capable of improving percutaneous absorbability and stability of nicorandils useful as a remedy for angina pectoris. CONSTITUTION:A percutaneous absorption pharmaceutical, obtained by blending nicorandil useful as the above-mentioned medicine and/or salts thereof with an absorbefacient consisting of combination of (A) a fatty acid ester, preferably an ester synthesized from a 10-18C fatty acid and a 1-20C alcohol, especially isopropyl myristate, etc., with (B) an N-acylsarcosine, fatty acid mono- or diethanolamides or alkylene oxide adducts thereof, preferably N-lauroylsarcosine, lauroylmono- or diethanolamide, etc., in a base and having excellent absorbability and stability of the aforementioned medicine.
JP8108388A 1987-04-01 1988-04-01 Percutaneous absorption pharmaceutical Pending JPS6425720A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8108388A JPS6425720A (en) 1987-04-01 1988-04-01 Percutaneous absorption pharmaceutical

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8027687 1987-04-01
JP8108388A JPS6425720A (en) 1987-04-01 1988-04-01 Percutaneous absorption pharmaceutical

Publications (1)

Publication Number Publication Date
JPS6425720A true JPS6425720A (en) 1989-01-27

Family

ID=26421316

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8108388A Pending JPS6425720A (en) 1987-04-01 1988-04-01 Percutaneous absorption pharmaceutical

Country Status (1)

Country Link
JP (1) JPS6425720A (en)

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