JPS6419A - Renal function-improving and diuretic agent - Google Patents
Renal function-improving and diuretic agentInfo
- Publication number
- JPS6419A JPS6419A JP63025058A JP2505888A JPS6419A JP S6419 A JPS6419 A JP S6419A JP 63025058 A JP63025058 A JP 63025058A JP 2505888 A JP2505888 A JP 2505888A JP S6419 A JPS6419 A JP S6419A
- Authority
- JP
- Japan
- Prior art keywords
- renal
- improving
- agent
- urine
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To obtain a renal function-improving and diuretic agent, by using a specific 8-chloro-benzothiazepine compound as an active component.
CONSTITUTION: The objective agent contains 2-(4-methoxyphenyl)-3- acetoxy-5-[2-(dimethylamino)ethyl]-8-chloro-2,3-dihydro-1,5-benzothiazepine-4(5H)- one known to have excellent hypotensive action and cerebral and coronary vasodilating action or its pharmacologically permissible acid addition salt as an active component. The agent remarkably improves the abnormality in urea nitrogen level and creatinine level in blood in a state of renal insufficiency, ameliorates and prevents the lesion of renal essential tissue in chronic renal insufficiency and increases the amount of urine and the sodium ion concentration and chlorine ion concentration in urine. The compound is administered at a rate of preferably 0.05W100mg/kg, especially 0.1W10mg/kg daily for adult.
COPYRIGHT: (C)1989,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63025058A JPH0737388B2 (en) | 1987-02-10 | 1988-02-04 | Renal function improving agent |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62-29396 | 1987-02-10 | ||
JP2939687 | 1987-02-10 | ||
JP63025058A JPH0737388B2 (en) | 1987-02-10 | 1988-02-04 | Renal function improving agent |
Publications (3)
Publication Number | Publication Date |
---|---|
JPS6419A true JPS6419A (en) | 1989-01-05 |
JPH0119A JPH0119A (en) | 1989-01-05 |
JPH0737388B2 JPH0737388B2 (en) | 1995-04-26 |
Family
ID=26362652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63025058A Expired - Lifetime JPH0737388B2 (en) | 1987-02-10 | 1988-02-04 | Renal function improving agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH0737388B2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE112009000695T5 (en) | 2008-03-19 | 2011-02-10 | Omron Healthcare Co., Ltd. | Electronic blood pressure monitor for measuring blood pressure according to volume compensation method |
US9815728B2 (en) | 2010-07-12 | 2017-11-14 | Corning Incorporated | Alumina isopipes for use with tin-containing glasses |
CN111447932A (en) * | 2017-12-11 | 2020-07-24 | 埃塔斯制药株式会社 | Renal dysfunction improving agent containing optical isomer of 1, 4-benzothiazepine-1-oxide derivative |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9062758B2 (en) | 2011-12-06 | 2015-06-23 | Sram, Llc | Chainring |
US9182027B2 (en) | 2011-12-06 | 2015-11-10 | Sram, Llc | Chainring |
JP2014148227A (en) | 2013-01-31 | 2014-08-21 | Yachiyo Industry Co Ltd | Fitting structure of fuel tank to vehicle body |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59225174A (en) * | 1983-06-03 | 1984-12-18 | Tanabe Seiyaku Co Ltd | Benzothiazepine derivative and its preparation |
-
1988
- 1988-02-04 JP JP63025058A patent/JPH0737388B2/en not_active Expired - Lifetime
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59225174A (en) * | 1983-06-03 | 1984-12-18 | Tanabe Seiyaku Co Ltd | Benzothiazepine derivative and its preparation |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE112009000695T5 (en) | 2008-03-19 | 2011-02-10 | Omron Healthcare Co., Ltd. | Electronic blood pressure monitor for measuring blood pressure according to volume compensation method |
DE112009000695B4 (en) | 2008-03-19 | 2017-11-09 | Omron Healthcare Co., Ltd. | Electronic blood pressure monitor for measuring blood pressure according to volume compensation method |
US9815728B2 (en) | 2010-07-12 | 2017-11-14 | Corning Incorporated | Alumina isopipes for use with tin-containing glasses |
CN111447932A (en) * | 2017-12-11 | 2020-07-24 | 埃塔斯制药株式会社 | Renal dysfunction improving agent containing optical isomer of 1, 4-benzothiazepine-1-oxide derivative |
Also Published As
Publication number | Publication date |
---|---|
JPH0737388B2 (en) | 1995-04-26 |
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