JPS6414000A - Testing agent for periodontosis - Google Patents

Testing agent for periodontosis

Info

Publication number
JPS6414000A
JPS6414000A JP17077987A JP17077987A JPS6414000A JP S6414000 A JPS6414000 A JP S6414000A JP 17077987 A JP17077987 A JP 17077987A JP 17077987 A JP17077987 A JP 17077987A JP S6414000 A JPS6414000 A JP S6414000A
Authority
JP
Japan
Prior art keywords
terminal
arg
pro
linking
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP17077987A
Other languages
Japanese (ja)
Other versions
JPH0650993B2 (en
Inventor
Toru Eguchi
Hirohisa Suidou
Koichi Nakajima
Kenji Hasegawa
Mitsuho Kanbara
Shoichi Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunstar Inc
Original Assignee
Sunstar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunstar Inc filed Critical Sunstar Inc
Priority to JP17077987A priority Critical patent/JPH0650993B2/en
Publication of JPS6414000A publication Critical patent/JPS6414000A/en
Publication of JPH0650993B2 publication Critical patent/JPH0650993B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Abstract

PURPOSE:To obtain a testing agent capable of objectively diagnosing or predicting morbidity or progress of periodontosis, by using a specific oligopeptide as a substrate for measuring aminopeptidase-like enzymic activity in a specimen. CONSTITUTION:One or two or more oligopeptides expressed by the formulas X-T-Pro-S and X-Z-Arg-Y (Pro represents proline residue; Arg represents arginine residue; X represents hydrogen or amino-protecting group; S represents a coloring group linking to the C-terminal of Pro; Y represents a coloring group linking to the C-terminal of Arg; T represents an amino acid or peptide residue having the C-terminal thereof, consisting of 1-4 amino acids or protected derivatives thereof and linking to the N-terminal of Pro; Z represents an amino acid or peptide residue having the C-terminal thereof, consisting of 1-4 amino acids or protected derivatives thereof and linking to the N-terminal of Arg) are used as a substrate for measuring aminopeptidase-like enzymic activity in a specimen and a buffer agent is added to the above-mentioned substrate to provide an aqueous solution. Alternatively, the afore-mentioned aqueous solution is impregnated into a suitable carrier.
JP17077987A 1987-07-08 1987-07-08 Periodontal disease test agent Expired - Lifetime JPH0650993B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17077987A JPH0650993B2 (en) 1987-07-08 1987-07-08 Periodontal disease test agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17077987A JPH0650993B2 (en) 1987-07-08 1987-07-08 Periodontal disease test agent

Publications (2)

Publication Number Publication Date
JPS6414000A true JPS6414000A (en) 1989-01-18
JPH0650993B2 JPH0650993B2 (en) 1994-07-06

Family

ID=15911217

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17077987A Expired - Lifetime JPH0650993B2 (en) 1987-07-08 1987-07-08 Periodontal disease test agent

Country Status (1)

Country Link
JP (1) JPH0650993B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003021370A (en) * 2001-07-05 2003-01-24 Matsushita Seiko Co Ltd Air cleaner for smoking

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003021370A (en) * 2001-07-05 2003-01-24 Matsushita Seiko Co Ltd Air cleaner for smoking

Also Published As

Publication number Publication date
JPH0650993B2 (en) 1994-07-06

Similar Documents

Publication Publication Date Title
Fleer et al. The primary structure of bovine pancreatic phospholipase A2
Yoshimoto et al. Postproline cleaving enzyme: identification as serine protease using active site specific inhibitors
US4314936A (en) Substrates for the quantitative assay of enzymes and such assay
ATE68014T1 (en) THE SYNTHESIS OF A PROTEIN USING AN IDENTIFICATION PEPTIDE.
BAUER et al. Specificity of a serum peptidase hydrolyzing thyroliberin at the pyroglutamyl‐histidine bond
DE3485568D1 (en) ALPHA AMINOBORONIC ACID PEPTIDES.
DE69634406D1 (en) METHOD FOR IN VITRO TESTING THE PROTEOLYTIC ACTIVITY OF POLYPEPTIDES WITH HCV NS3 PROTEASE ACTIVITY AS WELL AS PEPTIDE SUBSTRATES USED IN THIS METHOD
Han et al. Primary Structure of Bovine Plasma High-Molecular-Weight Kininogen The Amino Acid Sequence of a Glycopeptide Portion (Fragment 1) Following the C-Terminus of the Bradykinin Moiety
ES8607262A1 (en) Chromogenic esters of amino acids and peptides, processes for their preparation, use of these agents in methods of analysis and agents for detection of esterolytic and/or proteolytic enzymes.
Joys et al. o-Phthalaldehyde and the fluorogenic detection of peptides
Brezniak et al. Human. alpha.-to. zeta.-thrombin cleavage occurs with neutrophil cathepsin G or chymotrypsin while fibrinogen clotting activity is retained
TOMASSELLI et al. The complete amino acid sequence of adenylate kinase from baker's yeast
Allison et al. The subunits of dogfish M4 lactic dehydrogenase
Murakami et al. New fluorogenic substrates for renin
Lee et al. Does carboxypeptidase Y have intrinsic endopeptidase activity?
Kress et al. The Basic Trypsin Inhibitor of Bovine Pancreas: IX. LOCATION OF THE REACTIVE SITE IN THE CARBOXAMIDOMETHYL DERIVATIVE
Kubiak et al. In vitro metabolic degradation of a bovine growth hormone-releasing factor analog Leu27-bGRF (1-29) NH2 in bovine and porcine plasma. Correlation with plasma dipeptidylpeptidase activity.
GB2126720A (en) A method for determination of enzyme activity
JPS6414000A (en) Testing agent for periodontosis
McDonald et al. Angiotensinase activity of dipeptidyl aminopeptidase I (cathepsin C) of rat liver
Mobashery et al. Identification of amino acid residues involved in substrate recognition by the catalytic subunit of bovine cyclic AMP dependent protein kinase: peptide-based affinity labels
Porter et al. A rapid fluorometric assay for measurement of peptidase activity
WO1986001209A3 (en) New p-phenylenediamine peptides and reactance containing them for the determination of proteases of the blood coagulation system
Furihata et al. A new fluorescent microassay method for pepsin using succinyl-albumin
Walter et al. Synthetic metabolites of neurohypophyseal hormones.[Des-9-glycinamide] oxytocin and [des-9-glycinamide, des-8-leucine] oxytocin