JPS6348268Y2 - - Google Patents

Description

[Detailed Description of the Invention] () Background Technical Field of the Invention The present invention relates to a medicinal liquid container that allows the medicinal liquid sealed inside the container to be poured into other containers without coming into contact with the outside air.

Conventional technology and its problems Conventionally, glass ampoules or vials (with rubber stoppers) have been used as infusion containers for mixed injections with a small volume of about 50 ml, but the former can contain glass powder when opened, and is an open type. There is a risk of contamination if the chemical solution comes in contact with the outside air, and although the latter appears to be a closed system, when taking the required amount, usually the same amount of air as the required amount is pumped into the bottle beforehand, which also prevents contamination from outside air. There is a danger.

Therefore, there is a demand for a drug solution container that can dispense the drug solution in a completely closed system. The drug solution container shown in Fig. 1 is provided as a completely closed system vaccine dispensing device (syringe), and consists of a container part 1, a needle part 2, and a dust protection part 3, and the container part 1 has a tubular shape. A partition wall 1b, which can be penetrated by a needle, separates the main body part 1a from the cylindrical neck part 1c. The needle portion 2 is made up of a needle 2a and a metal ring 2b, and the ring 2b is slidably fitted into the neck portion 1c. The dust protection part 3 has an upper end closed and a lower end open, and is placed over the needle part 2 and has a flange 3a on the outer periphery of the intermediate part, and a part 3b below the flange 3a is slidably fitted to the neck part 1c. . Therefore, to perform mixed injection, as shown in FIG. 2, push the dust protection part 3 against the container part 1 and pierce the needle 2a into the partition wall 1b.After that, remove the dust protection part 3 and adjust the components (not shown) using the needle 2a. The drug is pierced through the rubber stopper of the drug solution container to compress the container part 1 and mixedly injected.

Therefore, this drug solution container has a small number of parts and a simple structure, and in particular, the needle 2a can penetrate the partition wall 1b by pushing the dust protection part 3 straight against the container part 1 instead of turning the screw. This is good, so handling during mixed injection is not troublesome, but if you try to pull the container part 1 away from the drug solution container (not shown) in which the ingredients have been adjusted after mixed injection, the metal ring 2b will come off from the cylindrical neck part 1c, and the needle part 2 will adjust the ingredients. It may remain stuck in the rubber stopper of the drug solution container.

Next, another conventional chemical liquid container shown in FIG. 3 will be explained. In the figure, 4 is a bottle, and 5 is a stopper, which seals a medicinal liquid into the bottle 4. The stopper 5 has a liquid passage 6a inside and a protrusion 6 having a male thread 6b on the outer surface.The protrusion 6 has a needle 7 on the male thread 6b.
It is screwed into a female thread of a socket portion 8a of a long hub 8 that supports the. The blade surface 7a of the needle 7 is the liquid passage 6a.
It is located inside and faces the partition wall 6c. A holder 9 supporting the hub 8 slidably accommodates the bottle 4. The blade surface 7b of the needle 7 is covered with a protective sheath 10. In the drug solution container configured as described above, by relatively screwing the holder 9 and the bottle 4, the male thread 6b on the outer surface of the projecting body 6 and the female thread on the socket portion 8a are tightened, and the blade surface 7a of the needle 7 is connected to the partition wall. 6c is pierced. Thereafter, the protective sheath 10 is removed and the blade surface 7b of the needle 7 is pierced into a rubber stopper (not shown) of a drug solution container whose components are to be adjusted, thereby performing mixed injection.

However, when the drug solution container is mixedly injected, the holder 9
Since it is necessary to screw the container 4 and the bottle 4 relative to each other, it is more time-consuming and troublesome than the chemical solution containers shown in FIGS. 1 and 2, and the structure is also complicated, resulting in high production costs.

() Purpose of the invention This invention has a simple structure with a small number of parts, and is a closed system that allows communication between the needle and the container body by pushing the needle straight against the container body. It provides a container.

According to the present invention, this purpose is to provide a flexible container body containing a medicinal liquid and having a hard cylindrical liquid outlet part;
A membrane body that can be penetrated by a needle and is provided to close the liquid passage of the liquid outlet portion, and a cap that supports the midway of the hollow needle body having blade surfaces at both ends and is fitted onto the outer surface of the liquid outlet portion. and further comprising: two annular grooves provided on either the outer surface of the liquid outlet portion or the inner surface of the cap at a required distance apart in the axial direction thereof, and also provided on the other and engaged with the annular groove. a two-stage locking means having one annular projection, and locking the cap at a first position and a second position on the outer surface of the liquid outlet portion by the two annular grooves and the one annular projection; The first position of the latching means is for positioning the container body side blade surface of the hollow needle outside the container body of the membrane body, and the second position is for positioning the container body side blade surface of the hollow needle body outside the container body. A liquid medicine container, characterized in that the side blade surface pierces the membrane body and is positioned inside the container body, and the hooking means is provided so as to be movable from the first position to the second position. It is achieved by doing so.

Further, in the latching means, the protrusion is an annular projection protruding inward from the inner peripheral surface of the cap, and the recesses are arranged circumferentially at required intervals in the longitudinal direction of the cylinder on the outer peripheral surface of the liquid outlet part of the container body. At least two annular grooves are provided, and the annular protrusion is fitted into the annular groove on the tip side of the liquid outlet so that the annular protrusion can be detached to the annular groove on the root side of the liquid outlet, or a protrusion. is an annular projection protruding outward from the outer surface of the liquid outlet portion of the container body, and the recess is an annular groove formed in the inner peripheral surface of the cap in the circumferential direction at a required interval in the longitudinal direction of the cylinder. The present invention provides a liquid medicine container in which the annular protrusion is removably fitted into the annular groove on the opening side of the liquid outlet housing hole so as to be removable toward the annular groove on the depth side of the liquid outlet housing hole.

In addition, the drug solution container of the present invention is designed so that it does not pass through the first stage of the latching state and be assembled to the second stage of the latching state by applying too much force when assembling it to the first stage of the latching state. Therefore, it is desirable to have a stopper inside the cap. Furthermore, inside the cap, there is fixedly housed a stopper made of a bottomed cylindrical elastic member that can be penetrated by a needle and whose bottom part is in contact with the membrane body and which covers and seals the inner needle tube part of the cap. A chemical liquid container houses a stopper made of a bendable bending member that is held between the inner surface of the cap and the liquid outlet part of the container body, and a stopper that is made of a bendable bending member that is held between the inner surface of the cap and the liquid outlet part of the container body. The present invention provides a drug solution container that houses a stopper made of a rupture member that is held in place.

() Specific explanation of the invention The invention will be explained with reference to FIGS. 4 and 5.

The drug solution container includes a flexible container body 11 having a hard cylindrical liquid outlet portion 11a, a membrane body 12 that can be penetrated by a needle and provided to close a liquid passage 11b of the liquid outlet portion 11a, and a membrane body 12 that can be penetrated by a needle. A hollow needle body 13 having a required length, which has at least two stages of locking means between it and the outer surface of the liquid outlet part 11a and has blade surfaces 13a and 13b at both ends, is supported midway near the blade surface 13, and the liquid outlet A cap 14 that fits into the portion 11a, and a bottomed cylindrical shape that covers the inner cap needle tube portion 13c, although it is not a necessary component, and a bottom portion 15a that fits into the membrane body 1.
A stopper 15 made of an elastic member capable of being penetrated by a needle, which is in contact with the hollow needle body 1 and which is closed at one end.
It consists of a protective sheath 16 that covers the blade surface 13a of No. 3. The container body 11 is molded from a soft synthetic resin that does not adversely affect the medicinal solution contained therein, and the liquid outlet portion 11a, which is required to be hard, is formed with a large wall thickness. The end of the liquid passage 11b is formed into a tapered hole that becomes larger in diameter in the direction of the end surface. Further, on the outer surface of the liquid outlet portion 11a, at least two annular grooves, which are one component of the above-mentioned at least two stages of latching means, are formed in the circumferential direction at required intervals in the longitudinal direction of the cylinder. It has recesses 17 and 18, and furthermore, the outer surface between the end face and the recess 17 is formed into a tapered cylindrical surface whose diameter becomes smaller in the direction of the end face, and the outer surface between the recess 17 and the recess 18 has no step difference from the recess 17 and the recess 18 It is formed into a tapered cylindrical surface with a larger diameter in the direction. The membrane body 12 is made of a liquid-tight material that can be penetrated by a needle, and a plastic film is attached to the end face of the liquid outlet portion 11a, or it is molded simultaneously with the molding of the container body 11. The container body 11 accommodates the chemical liquid 19 inside through the liquid injection port 11c, and the liquid injection port 11c is closed. The cap 14 has a protrusion 20, which is the other component of the above-mentioned at least two stages of latching means, formed as an annular protrusion projecting inward on its inner circumferential surface. The hollow needle body 13 is fitted with the annular groove 17 to constitute a first-stage latching means, thereby positioning the container body side blade surface 13b of the hollow needle body 13 outside the container body of the membrane body 12. The protrusion 20 has a claw-like cross section and is expanded in diameter so as to ride on a tapered surface that becomes larger in diameter from the recess 17 toward the recess 18.
It is now possible to leave to the side. The protrusion 20 and the recess 18 on the root side of the liquid outlet portion constitute a second-stage latching means, and as shown in FIG. The protrusion 2
0 fits into the recess 18, so that the container body side blade surface 13b pierces the stopper 15 and the membrane 12 and is positioned inside the container body 11. The stopper 15 is fixed to the inner front wall of the cap 14 with adhesive.

To assemble the drug solution container of the present invention, the liquid outlet portion 11a of the flexible container body 11 containing the drug solution therein.
A stopper 15 is provided inside to support the hollow needle body 12.
The cap 14 that fixedly houses the cap 14 is placed over the cap 14, and the cap 14 is pressed in the axial direction to forcibly fit the cap 14. Then, the protrusion 20 on the inner surface of the cap 14 fits into the recess 17 formed on the outer peripheral surface of the liquid outlet part 11a on the end face side of the liquid outlet part, thereby performing the first stage of locking. Particularly when the stopper 15 is provided inside the cap 14, the bottom 15a of the stopper 15 comes into contact with the end surface of the liquid outlet 11a, so in order to assemble the cap 14 into the first stage of latching state, the cap 14 is pressed with a little more force. Even if it is applied too much, part of the pressing force will be borne by the stopper 15 when trying to pass through the first stage of the latching state, so the pressing force on the cap 14 will be eased and unless the pressing force is quite large, the second stage will not be applied. Does not become stuck. Then, the hollow needle body 13 is covered with the protective sheath 16. In use, the cap 14 is pressed toward the container body while the protective sheath 16 remains covered.

Note that after removing the protective sheath 16, the cap 1
There is no problem even if you press 4. This pressing force is required to be slightly larger than the pressing force when assembling to the above-mentioned first-stage latched state, since it is necessary to press the stopper 15 when it is inside the cap 14. . Due to this pressing, the protrusion 20 causes a wedge action with the outer tapered cylindrical surface between the recess 17 and the recess 18 to expand the diameter of the recess 17.
At the same time, the stopper 15 moves out from the membrane body 1 and enters the second-stage latching state in which it is fitted into the recess 18.
The container body side blade surface 13b of the hollow needle body 13 is placed inside the container body by doubly piercing the stopper 15 and the membrane body 12, and the inside of the hollow needle body 13 and the inside of the container body 11 are communicated. In this case, the stopper 15 covers the membrane 12 and plays a double role in preventing liquid leakage from the liquid passage 11b. When the cap 14 reaches the second stage of engagement with the liquid outlet portion 11a, the protective sheath 16 is removed and the puncture side blade surface 13a of the hollow needle body 13 is pierced into the rubber stopper (not shown) of the drug solution container whose components are to be adjusted. The flexible container body 11 may be compressed with a finger to mix and inject the medicinal solution in the container. After the mixed injection, the user holds the container body 11 and pulls out the hollow needle 13 from the rubber stopper (not shown) of the drug solution container whose components have been adjusted. In this case, since this pulling force is smaller than the locking force of the protrusion 20 and the recess 18 that lock the cap 14 and the liquid outlet portion 11a, the cap 14 will not separate from the liquid outlet portion 11a.

As shown in FIG. 6, the protrusions and recesses of the latching means may be provided in the opposite manner to those of the above embodiment. That is, the protrusion 20 is an annular protrusion that protrudes outward in a circular direction from the outer surface of the liquid outlet portion 11a of the container body 11, and the recesses 17 and 18 are formed on the inner peripheral surface of the cap 14 at a required interval in the longitudinal direction of the cylinder. It may be an annular groove carved in the circumferential direction and spaced apart from each other.

In addition, the latching means has a structure that moves the cap in the axial direction and latches the cap and the liquid outlet part in at least two stages, and includes a protrusion other than the annular protrusion, the protrusion and at least two annular grooves. A configuration consisting of recesses other than the above may also be used. Furthermore, the latching means is not limited to the case where the cap is composed of a protrusion and a recess, but may be a means other than the protrusion and the recess that moves the cap in the axial direction and engages the outer surface of the liquid outlet portion in at least two stages. For the latching means, a particularly limiting condition is that the cap must be moved in the axial direction for latching in at least two stages, and that the latching means in the first stage should be in a position where the hollow needle does not pierce the membrane. , the second step is to set the position to be pierced by the latching means.

Next, as shown in FIG. 7, an optional stopper 21 housed within the cap 14 is a bendable stopper 21 made of plastic or metal material held between the inner surface of the cap and the liquid outlet portion 11a of the container body 11. It may also consist of a bending member. Alternatively, as shown in FIG. 8, the stopper 22 may be made of a soft plastic breakable member that is held between the inner surface of the cap and the liquid outlet portion 11a of the container body 11.

These stoppers 2 shown in FIGS. 7 and 8
1 and 22 may be members that cannot be penetrated by a needle. It is necessary to provide it so as not to interfere with the blade surface 13b of the hollow needle body 13 during the second stage of locking. Therefore, the stopper 21 made of a bending member shown in FIG. 7 has a side part 21a that passes through the hollow needle body 13 and comes into contact with the front wall and inner peripheral surface inside the cap 1, and a hole 21b that corresponds to the liquid passage 11b. Side part 2 that abuts on 12
1c and a connecting side 21d that connects both sides 21a and 21c in an S-shape and does not interfere with the blade surface 13b has been proposed as a specific example, and the stopper 22 made of a bending member shown in FIG. 8 is a hollow needle. body 1
3 and abuts against the front wall inside the cap 14, and a hole 22b corresponding to the liquid passage 11b.
A disk portion 22c that contacts the membrane body 12 and fits into the inner circumferential surface of the cap, and a disk portion 22c that connects both disk portions 22a, 22c, has a thin bend in the middle, and has a notch in the middle if necessary. As a specific example, a broken piece portion 22d that can be broken is proposed as a specific example.

() Specific effects of the invention As explained above, the drug solution container of the invention has
a hard cylindrical liquid outlet portion outer surface of the flexible container body;
A hollow needle having blade surfaces at both ends supports the middle part of the needle, and the cap is moved in the axial direction between the hollow needle body and the inner surface of the cap fitted into the liquid outlet part, and the cap is latched to the liquid outlet part in two stages. and positioning the hollow needle body outside the needle-pierceable membrane body blocking the liquid passage of the liquid outlet portion by the first-stage hanging means;
The system is constructed as a closed system in which the hollow needle is pierced through the membrane and positioned using the second-stage latching means.

Therefore, according to the liquid medicine container of the present invention, the number of parts is smaller and the structure is simpler than the conventional liquid medicine container shown in FIG. It is a closed system that allows the hollow needle body to communicate with the container body by a simple operation of pressing the dovetail cap against the liquid outlet in the axial direction, which eliminates the hassle of mixed injection. This method does not have the disadvantage that when the needle part inserted through the rubber stopper of a drug solution container whose composition has been adjusted by mixed injection is pulled out by holding the container body, the needle part comes off from the neck of the container body, as in the case of the drug solution container shown in FIG.

And, as an embodiment of the drug solution container of the present invention,
The latching means is composed of a protrusion and a recess, the protrusion is formed as an annular projection on either the outer surface of the liquid outlet part or the inner circumferential surface of the cap, and there are at least two recesses. If the cap is formed as an endless annular groove in the circumferential direction on the other side of the cap and the protrusion is releasably engaged with the recess that engages the first stage in the direction of the recess that engages the second stage, the cap is connected to the liquid outlet. When assembling the cap in the first stage of latching state with respect to the part, the circumferential position of the cap with respect to the liquid outlet part can be arbitrarily set.
Even if a twist is applied to the cap during the first stage of locking, the second stage of locking is performed.

Furthermore, as an embodiment of the present invention, a stopper that can be penetrated by a needle made of a bottomed cylindrical elastic member that covers the hollow needle body, a stopper made of a bending member, or a stopper made of a breakable member is housed in the cap, Even if the pressing force applied to the cap is slightly too large when assembling the cap to the liquid outlet in the first stage latching state, there is a risk that the first stage latching state will be exceeded and the second stage latching state will occur. This eliminates the possibility of the hollow needle piercing the membrane when assembling the grip.

[Brief explanation of drawings]

Figure 1 is a vertical cross-sectional front view of a conventional closed-type chemical liquid container before use, Figure 2 is a vertical cross-sectional front view of the main part of the same as above when in use, and Figure 3 is a longitudinal cross-sectional view of a conventional closed-type liquid chemical container before use. 4 is a longitudinal sectional front view of a preferred embodiment of the drug solution container of the present invention before use, FIG. According to a modified example, FIG. 6 is a longitudinal sectional front view of a main part in which the protrusions and recesses of the latching means are reversed from those of the embodiment shown in FIG. 4, and FIG. FIG. 8 is a longitudinal sectional front view of the main part in which the stopper is made of a bending member, and FIG. 8 is a longitudinal sectional front view of the main part in which the stopper is made of a breakable member. 11... Container body, 11a... Liquid outlet part, 11
b...liquid passage, 12...membrane body, 13...hollow needle body, 13a, 13b...blade surface, 14...cap, 15...stopper, 17, 18...recess,
20...protrusion, 21...stopper, 22...stopper.

Claims (1)

[Claims for Utility Model Registration] 1. A flexible container body containing a medicinal solution having a hard cylindrical liquid outlet, and a membrane that can be penetrated by a needle and provided to close a liquid passage at the liquid outlet. a cap that supports the middle of a hollow needle body having blade surfaces at both ends and is fitted onto an outer surface of the liquid outlet portion, and further includes either an outer surface of the liquid outlet portion or an inner surface of the cap. It has two annular grooves provided on one side separated by a required distance in the axial direction, and one annular protrusion provided on the other side that engages with the annular groove, and the two annular grooves and the one annular The protrusion forms a two-step locking means on the outer surface of the liquid outlet portion for locking the cap in a first position and a second position, and the first position of the locking means is located on the outer surface of the membrane body. The container body side blade surface of the hollow needle body is positioned outside the container body, and the second position is such that the container body side blade surface pierces the membrane body and is positioned inside the container body. . The drug solution container further characterized in that the locking means is movable from the first position to the second position. 2. The cap securely accommodates a stopper made of an elastic member capable of being penetrated by a needle, the cap having a closed-end cylindrical shape that caps and seals the inner needle tube portion and abuts the bottom of the cap against the membrane body. The drug solution container described in . 3. The liquid medicine container according to claim 1, wherein the cap securely accommodates a stopper made of a bendable bending member that is sandwiched between the inner surface of the cap and the liquid outlet of the container body. 4. The liquid medicine container according to claim 1, wherein the cap securely accommodates a stopper made of a breakable member which is sandwiched between the inner surface of the cap and the liquid outlet of the container body.