JPS6342363Y2 - - Google Patents
Info
- Publication number
- JPS6342363Y2 JPS6342363Y2 JP19217482U JP19217482U JPS6342363Y2 JP S6342363 Y2 JPS6342363 Y2 JP S6342363Y2 JP 19217482 U JP19217482 U JP 19217482U JP 19217482 U JP19217482 U JP 19217482U JP S6342363 Y2 JPS6342363 Y2 JP S6342363Y2
- Authority
- JP
- Japan
- Prior art keywords
- column
- support plate
- packing
- holder
- attached
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000012856 packing Methods 0.000 claims description 14
- 239000012528 membrane Substances 0.000 claims description 13
- 229920000642 polymer Polymers 0.000 claims description 13
- 238000004587 chromatography analysis Methods 0.000 claims description 6
- 238000009428 plumbing Methods 0.000 claims description 6
- 239000012530 fluid Substances 0.000 description 11
- 230000005526 G1 to G0 transition Effects 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 239000012466 permeate Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000004454 trace mineral analysis Methods 0.000 description 1
Landscapes
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Description
【考案の詳細な説明】
本考案はクロマトグラフイーのカラム担体支持
装置に関するものである。[Detailed Description of the Invention] The present invention relates to a column carrier support device for chromatography.
各種物質の微量分析に用いられるクロマトグラ
フイーにおいては、カラム内へ導入した流体及び
分析すべき試料を、カラム底部に配置した支持板
により支持せしめる固定相内へ展開させ、試料の
成分を分離させた後、予めカラムに連通させた配
管パイプへ流体を排出することが行われている。 In chromatography, which is used for trace analysis of various substances, the fluid introduced into the column and the sample to be analyzed are developed into a stationary phase supported by a support plate placed at the bottom of the column, and the components of the sample are separated. After that, the fluid is discharged into a piping connected to the column in advance.
このようなカラム担体支持装置としては従来第
１図に示すものが知られている。 As such a column carrier support device, one shown in FIG. 1 is conventionally known.
同図においてカラム１の端部１ａは、カラム用
ホルダー２に形成されたカラム取付孔３にパツキ
ン４を介して取り付けされ、かつそのパツキン４
の内周には例えば焼結フイルターの如き多孔性で
かつ円板状の固定相用の支持板５が配置されてい
る。 In the figure, an end portion 1a of a column 1 is attached to a column mounting hole 3 formed in a column holder 2 via a packing 4, and the packing 4 is attached to a column mounting hole 3 formed in a column holder 2.
A porous, disc-shaped support plate 5 for the stationary phase, such as a sintered filter, is disposed on the inner periphery of the support plate 5 .
カラム取付孔３は、カラム用ホルダー２に形成
した連通孔６を介してパイプ取付孔７に連通さ
れ、そのパイプ取付孔７に配管ジヨイント８を介
して配管用パイプ９を取り付けし、カラム１を支
持板５および連通孔６を介して配管用パイプ９に
連通させたものである。 The column attachment hole 3 is communicated with a pipe attachment hole 7 through a communication hole 6 formed in the column holder 2, and a piping pipe 9 is attached to the pipe attachment hole 7 via a piping joint 8 to attach the column 1. It is connected to a plumbing pipe 9 via a support plate 5 and a communication hole 6.
しかしながらこのようなカラム担体支持装置に
おいては、支持体５の孔径を所望の径とすること
が困難で、その支持体５を通過する流体とともに
固定相を形成する担体が孔の内部にはいり込んで
積層し、支持板５の流体抵抗が増大し、分析精度
を低下させたり、カラム１内へ保持させるべき担
体が支持板５を通過してしまう欠点が存してい
た。 However, in such a column carrier support device, it is difficult to set the pore diameter of the support 5 to a desired diameter, and the carrier that forms the stationary phase together with the fluid passing through the support 5 may get into the pores. Due to the stacking, the fluid resistance of the support plate 5 increases, resulting in a decrease in analysis accuracy and the disadvantage that carriers to be held in the column 1 pass through the support plate 5.
本考案は上述した従来のカラム担体支持装置の
欠点に鑑み、カラム１から配管用パイプ９へ流れ
る流体とともに担体が支持板５内に至りその内部
に積層したり、通過したりすることのないカラム
担体支持装置の提供を目的とするものであり、か
かる本考案の目的はカラムの端部を、パツキンを
介してカラム用ホルダーに形成したカラム取付孔
に取り付けし、カラム用ホルダーの他側には前記
カラム取付孔に連通させつつ配管パイプを取り付
けし、前記パツキンの内周に円板状で多孔性の支
持板を配置し、その支持板のカラム側の端面を被
覆させた高分子透過膜の外周部を、前記パツキン
の内周面と支持板の外周面間に嵌入させたことを
特徴としてなるクロマトグラフイーのカラム担体
支持装置により達成される。 In view of the above-mentioned drawbacks of the conventional column carrier support device, the present invention provides a column in which the carrier does not reach the support plate 5 together with the fluid flowing from the column 1 to the piping pipe 9, and does not stack or pass through the support plate 5. The purpose of the present invention is to provide a carrier support device, and the purpose of the present invention is to attach the end of a column to a column mounting hole formed in a column holder via a packing, and to attach a column to a column mounting hole formed in a column holder on the other side of the column holder. A plumbing pipe is attached while communicating with the column mounting hole, a disc-shaped porous support plate is arranged on the inner periphery of the packing, and the end face of the support plate on the column side is covered with a polymer permeable membrane. This is achieved by a column carrier support device for chromatography characterized in that the outer circumferential portion is fitted between the inner circumferential surface of the packing and the outer circumferential surface of the support plate.
以下に第２図を参照し本考案の一実施例を説明
する。 An embodiment of the present invention will be described below with reference to FIG.
同図中、１０はカラム担体支持装置であり、筒
状のカラム１１の端部を支持するカラム用ホルダ
ー１２を備えている。 In the figure, reference numeral 10 denotes a column carrier support device, which includes a column holder 12 that supports the end of a cylindrical column 11.
カラム用ホルダー１２の一側には、内周にねじ
１３を有するカラム取付孔１４が形成してあり、
そのねじ１３にカラム１１の端部外周に形成した
ねじ１１ａを螺合させることにより、カラム１１
をカラム用ホルダー１２に取り付けしている。 A column mounting hole 14 having a screw 13 on the inner periphery is formed on one side of the column holder 12.
By screwing together the screw 13 with the screw 11a formed on the outer periphery of the end of the column 11, the column 11
is attached to the column holder 12.
カラム１１の端縁１１ｂとカラム取付孔１４の
底部１４ａの間に環状のパツキン１５を介在さ
せ、そのパツキン１５の内周に円板状でかつ多孔
性の焼結フイルターの如き支持板１６を配置して
いる。その支持板１６の一方の面すなわちカラム
１１側の端面をテフロン（登録商標名）の如き高
分子透過膜１７により被覆している。 An annular packing 15 is interposed between the edge 11b of the column 11 and the bottom 14a of the column attachment hole 14, and a support plate 16 such as a disk-shaped porous sintered filter is arranged on the inner periphery of the packing 15. are doing. One surface of the support plate 16, that is, the end surface on the column 11 side, is covered with a polymer permeable membrane 17 such as Teflon (registered trademark).
高分子透過膜１７の外周部を前記パツキン１５
の内周面と支持板１６の外周面間に嵌入させてい
る。 The outer periphery of the polymer permeable membrane 17 is attached to the packing 15.
and the outer peripheral surface of the support plate 16.
前記カラム用ホルダー１２の他側には、内周面
にねじ１８を有するパイプ取付孔１９が形成して
あり、そのねじ１８に配管ジヨイント２１のねじ
２２を螺合させ、その中心部を貫通させた配管用
パイプ２０をカラム用ホルダー１２に取り付けし
ている。 A pipe mounting hole 19 having a thread 18 on the inner peripheral surface is formed on the other side of the column holder 12, and the thread 22 of the piping joint 21 is screwed into the thread 18, passing through the center thereof. A piping pipe 20 is attached to the column holder 12.
配管用パイプ２０の端部を、カラム用ホルダー
１２の内部において前記カラム取付孔１３に連通
させて形成した連通孔２４に臨ませている。 The end of the plumbing pipe 20 faces a communication hole 24 formed inside the column holder 12 to communicate with the column attachment hole 13 .
上述の構成からなるカラム担体支持装置１０の
作用について説明する。 The operation of the column carrier support device 10 having the above-described configuration will be explained.
カラム１１内に導入された流体は、担体Ｘが充
填されている固定相を経て高分子透過膜１７及び
支持板１６を透過し、連通孔２４を経て配管用パ
イプ２０に流れる。この場合に担体Ｘの粒子の直
径は通常数μ乃至数十μ程度であるため、担体Ｘ
は高分子透過膜１７に遮られてカラム１１内に保
持され、流体のみが高分子透過膜１７を透過す
る。 The fluid introduced into the column 11 passes through the stationary phase filled with the carrier X, passes through the polymer permeable membrane 17 and the support plate 16, and flows into the plumbing pipe 20 through the communication hole 24. In this case, since the diameter of the particles of carrier X is usually about several microns to several tens of microns, carrier
is blocked by the polymer permeable membrane 17 and held in the column 11, and only the fluid permeates through the polymer permeable membrane 17.
また予めカラム１１のカラム用ホルダー１２に
対する締付状態を強固にしておくことによつて、
パツキン１５はカラム１１の端部に押圧されて膨
出し、高分子透過膜１７の外周部を支持板１６の
外周面に圧接させるため、高分子透過膜１７は支
持板１６に密着せしめられるとともに外部への流
体もれを防止する。 In addition, by tightening the column 11 to the column holder 12 in advance,
The packing 15 is pressed against the end of the column 11 and swells, and the outer circumference of the polymer permeable membrane 17 is brought into pressure contact with the outer circumferential surface of the support plate 16, so that the polymer permeable membrane 17 is brought into close contact with the support plate 16 and externally. Prevent fluid leakage.
以上の説明から明らかなように本考案に係るク
ロマトグラフイーのカラム担体支持装置は、分析
すべき試料を固定相内へ展開させた流体を、カラ
ムの底部に配置した高分子透過膜を介して透過さ
せるようにしたものであるから、カラム内に充填
された担体は高分子透過膜に遮られ、流体のみが
透過することになる。 As is clear from the above description, the chromatography column carrier support device according to the present invention allows the fluid in which the sample to be analyzed to be developed into the stationary phase to be passed through the polymer permeable membrane placed at the bottom of the column. Since it is designed to allow permeation, the carrier packed in the column is blocked by the polymer permeable membrane, allowing only the fluid to permeate.
したがつて従来の如く支持板の孔に担体が積層
したり通過したりすることを防止することがで
き、クロマトグラフイーによる分析精度の均一化
を図り得るものである。 Therefore, it is possible to prevent the carriers from stacking up or passing through the holes of the support plate as in the prior art, and it is possible to equalize the accuracy of analysis by chromatography.
また高分子透過膜の外周部を、カラムの端部に
より押圧させるパツキンの内周面と多孔性の支持
板の外周面間に嵌入させたことによつて、流体の
シール機能を向上し得たものである。 Furthermore, by fitting the outer circumference of the polymer permeable membrane between the inner circumference of the packing pressed by the end of the column and the outer circumference of the porous support plate, the fluid sealing function was improved. It is something.
第１図は従来のカラム担体支持装置を示す省略
断面図、第２図は本考案のカラム担体支持装置の
一実施例を示す省略断面図である。
１０……カラム担体支持装置、１１……カラ
ム、１２……カラム用ホルダー、１４……カラム
取付孔、１５……パツキン、１６……支持板、１
７……高分子透過膜、２０……配管用パイプ。
FIG. 1 is an abbreviated sectional view showing a conventional column carrier support device, and FIG. 2 is an abbreviated sectional view showing an embodiment of the column carrier support device of the present invention. 10... Column carrier support device, 11... Column, 12... Column holder, 14... Column mounting hole, 15... Packing, 16... Support plate, 1
7...Polymer permeable membrane, 20...Plumbing pipe.
Claims (1)
ルダーに形成したカラム取付孔に取り付けし、カ
ラム用ホルダーの他側には前記カラム取付孔に連
通させつつ配管パイプを取り付けし、前記パツキ
ンの内周に円板状で多孔性の支持板を配置し、そ
の支持板のカラム側の端面を被覆させた高分子透
過膜の外周部を、前記パツキンの内周面と支持板
の外周面間に嵌入させたことを特徴としてなるク
ロマトグラフイーのカラム担体支持装置。 The end of the column is attached to the column mounting hole formed in the column holder through the packing, and a plumbing pipe is attached to the other side of the column holder while communicating with the column mounting hole, and the inner circumference of the packing is attached. A porous disk-shaped support plate is arranged in the column, and the outer circumference of the polymer permeable membrane covering the column-side end face of the support plate is inserted between the inner circumference of the packing and the outer circumference of the support plate. A chromatography column carrier support device characterized by:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19217482U JPS5997463U (en) | 1982-12-21 | 1982-12-21 | Chromatography column carrier support device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19217482U JPS5997463U (en) | 1982-12-21 | 1982-12-21 | Chromatography column carrier support device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5997463U JPS5997463U (en) | 1984-07-02 |
| JPS6342363Y2 true JPS6342363Y2 (en) | 1988-11-07 |
Family
ID=30413639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP19217482U Granted JPS5997463U (en) | 1982-12-21 | 1982-12-21 | Chromatography column carrier support device |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5997463U (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4972329B2 (en) * | 2006-03-27 | 2012-07-11 | 株式会社日立ハイテクノロジーズ | High performance liquid chromatograph column and high performance liquid chromatograph |
-
1982
- 1982-12-21 JP JP19217482U patent/JPS5997463U/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5997463U (en) | 1984-07-02 |
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