JPS63160665A - Ceramic coated implant - Google Patents
Ceramic coated implantInfo
- Publication number
- JPS63160665A JPS63160665A JP61307849A JP30784986A JPS63160665A JP S63160665 A JPS63160665 A JP S63160665A JP 61307849 A JP61307849 A JP 61307849A JP 30784986 A JP30784986 A JP 30784986A JP S63160665 A JPS63160665 A JP S63160665A
- Authority
- JP
- Japan
- Prior art keywords
- coating layer
- ceramic
- implant
- metal
- coated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000919 ceramic Substances 0.000 title claims description 34
- 239000007943 implant Substances 0.000 title claims description 34
- 239000011247 coating layer Substances 0.000 claims description 56
- 229910052751 metal Inorganic materials 0.000 claims description 21
- 239000002184 metal Substances 0.000 claims description 21
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 16
- 239000001506 calcium phosphate Substances 0.000 claims description 15
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 14
- 235000011010 calcium phosphates Nutrition 0.000 claims description 14
- 229910010293 ceramic material Inorganic materials 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 10
- 229910052586 apatite Inorganic materials 0.000 claims description 7
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 claims description 7
- 229910052721 tungsten Inorganic materials 0.000 claims description 5
- 229910000599 Cr alloy Inorganic materials 0.000 claims description 4
- 239000010935 stainless steel Substances 0.000 claims description 4
- 229910001220 stainless steel Inorganic materials 0.000 claims description 4
- 150000002739 metals Chemical class 0.000 claims description 3
- 229910052750 molybdenum Inorganic materials 0.000 claims description 3
- 238000003466 welding Methods 0.000 claims description 3
- 229910001069 Ti alloy Inorganic materials 0.000 claims description 2
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 2
- 238000010030 laminating Methods 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 description 15
- 239000002585 base Substances 0.000 description 10
- 239000010410 layer Substances 0.000 description 10
- 239000000463 material Substances 0.000 description 9
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 5
- 230000000399 orthopedic effect Effects 0.000 description 5
- 239000011575 calcium Substances 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 4
- 238000000576 coating method Methods 0.000 description 4
- 230000007797 corrosion Effects 0.000 description 4
- 238000005260 corrosion Methods 0.000 description 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 3
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 3
- 239000010953 base metal Substances 0.000 description 3
- 229910052791 calcium Inorganic materials 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 210000002414 leg Anatomy 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 238000010828 elution Methods 0.000 description 2
- 210000002540 macrophage Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229910052698 phosphorus Inorganic materials 0.000 description 2
- 239000011574 phosphorus Substances 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 235000019731 tricalcium phosphate Nutrition 0.000 description 2
- 229910000851 Alloy steel Inorganic materials 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- -1 ZrOt Inorganic materials 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 150000001342 alkaline earth metals Chemical class 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- APUPEJJSWDHEBO-UHFFFAOYSA-P ammonium molybdate Chemical compound [NH4+].[NH4+].[O-][Mo]([O-])(=O)=O APUPEJJSWDHEBO-UHFFFAOYSA-P 0.000 description 1
- 229940010552 ammonium molybdate Drugs 0.000 description 1
- 235000018660 ammonium molybdate Nutrition 0.000 description 1
- 239000011609 ammonium molybdate Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000005524 ceramic coating Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 208000031513 cyst Diseases 0.000 description 1
- 239000004053 dental implant Substances 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000007772 electroless plating Methods 0.000 description 1
- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 description 1
- 210000004969 inflammatory cell Anatomy 0.000 description 1
- 229910003002 lithium salt Inorganic materials 0.000 description 1
- 159000000002 lithium salts Chemical class 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 150000003016 phosphoric acids Chemical class 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000009864 tensile test Methods 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
- Prostheses (AREA)
- Dental Prosthetics (AREA)
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
（産業上の利用分野）
この范明は、歯科、整形外科の分野において使用される
医療用のインプラントに関する。DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) This invention relates to medical implants used in the fields of dentistry and orthopedics.
（従来の技術）
近年、Ｃｏ−Ｃｒ合金、Ｔ１合金、ステンレス環のイン
プラントが多数医療分骨で使用されているが、長期間こ
のインプラントラ体内に埋設されることで、体内の組織
液や体液により、又体内での組機体との＃擦によってイ
ンプラントが腐食されてしまい、インプラント基体の成
分イオンが溶出してしまい、マクロファージを損傷した
り、細胞内に侵入することにより炎症性細胞や巨犬訓胞
ボ生の原因となるものである。そのためインプラント基
材の表面にコーティング等の表面処理分施し、インプラ
ント基材の成分イオンの溶出を防止するものが多く堤案
されている（特公昭４９−２４４２９号、特開昭５９−
８２８４９号、特開昭６１−１７６３５４号）。(Prior art) In recent years, many Co-Cr alloy, T1 alloy, and stainless steel ring implants have been used in medical bone implants. In addition, the implant is corroded due to friction with the assembled body in the body, and the component ions of the implant base are eluted, damaging macrophages and invading into cells, causing inflammatory cells and macrophages. This is the cause of cysts. Therefore, many proposals have been made to prevent the elution of component ions from the implant base material by applying surface treatments such as coating to the surface of the implant base material (Japanese Patent Publication No. 49-24429, JP-A No. 59-1999).
No. 82849, JP-A-61-176354).
（発明が解決しようとする問題点）
しかしながら、上記従来のものにおいても未だ耐腐食性
、耐久性、生体親和性が不十分なものであり、特にイン
プラント基体のコーテイング材としてよく用いられる燐
酸カルシウム材料は、長期にわたり体内に埋入すると骨
に転化するため、骨と生体金属とが直接に接触すること
となり、生体金属の腐食による為害性を現すこととなり
、長期間使用する整形外科用としては不適当なものとな
る。そこで、この発明は上記従来のもののもつ欠点を改
善するものであり、インプラントの耐蝕性、耐久性、生
体親和性を十分に向上させ、インプラントの長期間使用
に対して十分に安全を確保しようとするものである。(Problems to be Solved by the Invention) However, even the above-mentioned conventional products still have insufficient corrosion resistance, durability, and biocompatibility, especially calcium phosphate materials that are often used as coating materials for implant substrates. When implanted in the body for a long period of time, it converts into bone, which results in direct contact between the bone and biometal, which can cause harm due to corrosion of the biometal, making it unsuitable for orthopedic use for long-term use. It becomes appropriate. Therefore, this invention aims to improve the above-mentioned drawbacks of the conventional methods, and aims to sufficiently improve the corrosion resistance, durability, and biocompatibility of implants, and to ensure sufficient safety for long-term use of implants. It is something to do.
（問題点を解決するための手段）
ステンレス、Ｃｏ−Ｃｒ合金、Ｔｉ合金等の生体金属よ
りなるインプラント基体の表面に生体為害性の少い金属
を被覆した第１被覆層を設け、次にこの第１被覆層の上
に、生体為害性の少な＾金属を被覆したセラミック粉末
を溶着して形成する第２被覆層を設け、この被覆層上に
１セラミツク粉末と連なるセラミック材よりなる第３被
慢層を設けその１忙アパタイト又はリン酸カルシウムよ
り形成する第４被覆層を積層してなるセラミック被覆イ
ンプラントを提供することにより解決するもので第１、
第２被覆層の生体為害性の少い金属としてはＷ 、 Ｍ
ｏ及び／又はＧｅが適している。(Means for solving the problem) A first coating layer coated with a metal that is less harmful to the living body is provided on the surface of an implant base made of a biometal such as stainless steel, Co-Cr alloy, Ti alloy, etc. On the first coating layer, a second coating layer is formed by welding ceramic powder coated with a metal that is less harmful to the body, and on this coating layer, a third coating layer made of a ceramic material connected to the first ceramic powder is provided. The first problem is solved by providing a ceramic-coated implant comprising a ceramic layer and a fourth coating layer made of apatite or calcium phosphate.
Metals with less biotoxicity for the second coating layer include W and M.
o and/or Ge are suitable.
（作用） 以上の構成を具えるので、第１被覆層のＭＯ，Ｗ。(effect) Since it has the above configuration, MO and W of the first coating layer.
Ｑｅ等の生体為害性の少ない金属層によってインプラン
ト基体面を被覆するのでその表面の腐食、その表面より
溶出する金属イオンを阻止すると共に、Ｍｏ 、 Ｗ
、 Ｇｅと基体となる生体金属との結合を金属同士の金
属結合によって強固に結合する。Since the implant base surface is coated with a metal layer such as Qe that is less harmful to the body, corrosion of the surface and metal ions eluted from the surface are prevented, and Mo, W
, Ge and the biological metal serving as the base are strongly bonded by metal-to-metal bonding.
次に、第２被覆層セラミックを露出させることにより、
セラミック材を有する第２被覆層と第３被覆層がセラミ
ック結合により強固に接合する。Next, by exposing the second coating layer ceramic,
The second coating layer and the third coating layer having a ceramic material are firmly joined by ceramic bonding.
これにより基体金属からセラミックの第３被覆層迄連続
した強固な結合を有すると共に金属とセラミンクの熱膨
張差による内部応力も緩和する。このように自然に且つ
、強固に結合することができるので、第２被覆層の剥離
を防ぎ、しかも、第３被覆層のセラミックがアパタイト
又はリン酸カルシウムによる第４被覆層とセラミック相
立の結合により強固に結合でき、更にまた第４被覆層は
骨と結合して、前転化をするものであり、生体く害を与
えることなしに、強固なインプラントとして使用できる
ものである。This provides a continuous and strong bond from the base metal to the third ceramic coating layer, and also relieves internal stress due to the difference in thermal expansion between the metal and the ceramic. Since it is possible to bond naturally and strongly in this way, peeling of the second coating layer is prevented, and moreover, the ceramic of the third coating layer is strongly bonded to the fourth coating layer of apatite or calcium phosphate by the ceramic mutual bond. Furthermore, the fourth covering layer can be bonded to bone and undergo forward transformation, and can be used as a strong implant without causing harm to living organisms.
（実権例） この発明を図に示す実施例により更に説明する。(Example of actual power) This invention will be further explained with reference to embodiments shown in the drawings.
第１図において（１）は、整形外科用に用いられるイン
プラントであり、このセラミック被覆インプラント（１
）は、骨Ｃ５ｉ部（力とステム（］１からなり、このス
テム（１９は、ステンレス（ＳｕＳ ３１６ ） 、
Ｃｏ −Ｃｒ合金（Ｃｏ −３０Ｃｒ −７Ｍｏ鋳造用
、Ｃｏ−２１Ｃｒ −１６Ｗ−１１Ｎｉ加工用）ｙ’ｒ
ｔ合金（Ｔｉ −６ＡＡ−４Ｖ ）等の生体金属材料で
あり、高強度金属であるインプラント基体（２）上に、
まず生体為害性の少ないＷ。In Fig. 1, (1) is an implant used for orthopedics, and this ceramic-coated implant (1) is an implant used for orthopedics.
) consists of a bone C5i part (force) and a stem (]1, this stem (19 is made of stainless steel (SuS 316),
Co-Cr alloy (for Co-30Cr-7Mo casting, Co-21Cr-16W-11Ni processing)
On the implant base (2), which is a biometallic material such as t-alloy (Ti-6AA-4V) and is a high-strength metal,
First of all, W is less harmful to living organisms.
Ｍｏ、Ｑｅの金属薄膜（，３）を無電震メッキ法により
被覆し、これを第１被覆層（３）とし、この第１被覆層
の上に上記生体為害性の少いｗ、Ｍｏ、ｃｅの金属被覆
（至）を設けた、（被覆層の厚さ０．５〜８μ）燐酸力
ｙシウムに親和性のあるセラミック粉αゆを溶着して第
２被覆層（４）を形成する、このセラミック粉は望まし
くは粒度１０μ〜２００μであって、アパタイト、リン
酸カルシウム、アルミナ、 Ｚｒ０ｔ、 Ｓｉ、Ｎ、
、 ＳｉＣ、ＴｉＮ ６るいは、ＴＣＰ （３ＣａＣ０
゜ｐ、ｏ、であることが望ましい。Ｗ 、 Ｍｏ 、Ｇ
ｅ等の金属は、タングステン酸アンモン又はモリブデン
酸アンモンの３０チ水溶液に潰して、乾燥を繰返した後
、Ｈ１中で１元焼結し、形成したものであり、この金属
により被覆されるセラミックは前記のようＫＡｒガスを
用いたプラズマ（第３図矢印）にて基体（３）上に溶射
して、第２被覆層（４）を形成するものである。（第３
図左方に示す）さらに、セラミック０１表面を露出させ
るなめに、ダイヤモンド砥石で表面を研磨し、上面の金
属被覆層（ハ）を除き平滑な第２被覆層（４）を形成す
る（第３図右方に示す。）この第２被覆層は上記のよう
な金属セラミックにこだわらずセラミックと金属との混
合粉末でも形成することができる。A metal thin film (, 3) of Mo, Qe is coated by an electroless plating method, and this is used as a first coating layer (3). A second coating layer (4) is formed by welding a ceramic powder having an affinity for phosphoric acid (with a coating layer thickness of 0.5 to 8 μm) and a metal coating (up to). This ceramic powder preferably has a particle size of 10μ to 200μ and contains apatite, calcium phosphate, alumina, ZrOt, Si, N,
, SiC, TiN 6 or TCP (3CaC0
It is desirable that ゜p, o. W, Mo, G
Metals such as e are crushed in a 30% aqueous solution of ammonium tungstate or ammonium molybdate, dried repeatedly, and then sintered in one unit in H1, and the ceramic coated with this metal is As described above, the second coating layer (4) is formed by spraying onto the substrate (3) using plasma (arrow in FIG. 3) using KAr gas. (3rd
(shown on the left side of the figure) Furthermore, in order to expose the surface of the ceramic 01, the surface is polished with a diamond grindstone to remove the metal coating layer (c) on the top surface and form a smooth second coating layer (4) (the third (Shown on the right side of the figure.) This second coating layer is not limited to the above-mentioned metal ceramic, but can also be formed using a mixed powder of ceramic and metal.
上記第２被覆層の表面（４）の上に、第２被覆層（４）
の露出したセラミックＣｔ４と結合するように１セラミ
ツク材で被覆して第３被覆層（５）を設ける。A second coating layer (4) is formed on the surface (4) of the second coating layer.
A third coating layer (5) is provided by coating with a ceramic material so as to bond with the exposed ceramic Ct4.
このセラミック材料は基本的に述べれば第２被覆層に用
いた材料で良い。その場合第２被覆層と同物質であれば
その間の接着力は最も確実なものであるがこの発明はこ
れＫこだわることなく異物質でも可能である、何れの場
合もセラミックーセラミックの結合親和性は良好である
ため強い化学結合力が得られるものである。この第３被
覆層（５）の表面、すなわち、外方には、生体親和性の
高いアパタイト又はリン酸カルシウムよりなる第４被覆
層（６）を積層してなるものである。この工程の最も具
体的な例を述べれば、市販の試薬１級のＣａＣ０−とｐ
、ｏ、をＣａ／Ｐの原子比が１．５ Ｋなるように配合
し、１２００℃に焼成して後、冷却徨粉砕してトリカル
シウム７オス７エートの微粉末を得てから、これを１９
にの有機質結合剤と共に５０％の水圧入れ攪拌して燐酸
カルシウム塩のスリップとし、前記第３被覆層の上に付
着し１、乾燥后大気中１０００℃にて焼きつけテストピ
ースとした。このようにして製作した３ｗφ×２０ＷＪ
の円柱状テストピースを成兎の大腿骨に埋入したところ
、約１カ月で第４被覆層は骨に転化し念。又２０ｍＸ２
（）■×５園の直方体に製作したテストピースの主表面
にゴム板を接着し１ｏｘｙの力で引張ることを４０回繰
り返したが、剥離することはなかった。併し比較の念め
第２被覆層をＧｅのみとして製作したテストピースは１
０回の引張りテストで剥離した。Basically, this ceramic material may be the material used for the second coating layer. In that case, if the material is the same as that of the second coating layer, the adhesive force between them will be the most reliable, but this invention is not limited to this, and can be made of a different material.In either case, the bonding affinity of ceramic-ceramic is good, so a strong chemical bonding force can be obtained. A fourth coating layer (6) made of apatite or calcium phosphate, which has high biocompatibility, is laminated on the surface of the third coating layer (5), that is, on the outside. The most specific example of this process is the commercially available reagent grade 1 CaC0- and p
, o, were blended so that the atomic ratio of Ca/P was 1.5 K, calcined at 1200°C, cooled and crushed to obtain a fine powder of tricalcium 7-mole-7-ate, and then 19
A slip of calcium phosphate salt was obtained by press-fitting and stirring with 50% water together with an organic binder, and the slip was adhered onto the third coating layer 1. After drying, it was baked at 1000° C. in the atmosphere to form a test piece. 3wφ×20WJ manufactured in this way
When a cylindrical test piece was implanted into the femur of an adult rabbit, the fourth covering layer was transformed into bone in about a month. Also 20mX2
A rubber plate was glued to the main surface of a test piece made in the shape of a rectangular parallelepiped ()■×5 and pulled with a force of 1oxyy 40 times, but no peeling occurred. However, for comparison, the test piece made with only Ge as the second coating layer was 1.
It peeled off after 0 tensile tests.
なお、この実施例では一例として上記トリカルシウムフ
ォスフェートについて述べたが、この発明はこれＫこだ
わることなく特開昭５５−５６０６２号「高強度リン酸
カルシウム焼結体の製造方法」Ｋ述べられた［カルシウ
ム／リン原子比１．４〜１．７５のカルシウムのリン酸
塩を主体とする粉末に、焼成９嘱のリン酸カルシウム成
分九対し、０．５〜１５重ｔｅｓのカルシウム／リン原
子比０．２〜０．７５を有するカルシウム・リン酸系７
リツトを添加混合したもの、又は特開昭５５−１４０７
５６号「高強度リン酸カルシウム焼結体」に述べられた
カルシウム／リン原子比１．４〜１．７５のカルシウム
のリン酸塩を主体とする粉末に、焼成層のリン酸カルシ
ウム焼結体に対し、０．５〜１５重量−のアルカリ金属
、亜鉛及び／又はアルカリ土類金属の酸化物−リン酸系
７リツトを含有せしめたものを用いてもよい。In this embodiment, the above-mentioned tricalcium phosphate was described as an example, but this invention is not limited to this. Powder mainly composed of calcium phosphate with a /phosphorus atomic ratio of 1.4 to 1.75, 9 times of calcined calcium phosphate components, and a calcium/phosphorus atomic ratio of 0.2 to 0.5 to 15 times Calcium phosphate system 7 with 0.75
mixture with addition of lithium salt, or JP-A-55-1407
56 "High Strength Calcium Phosphate Sintered Body" powder mainly composed of calcium phosphate with a calcium/phosphorous atomic ratio of 1.4 to 1.75, A material containing 7 liters of an oxide of an alkali metal, zinc and/or alkaline earth metal and phosphoric acid in an amount of .5 to 15% by weight may also be used.
こ＼でこの発明の一実施形聾として第２被覆層のセラミ
ック材料、第３被覆層のセラミック材料、第４被覆層セ
ラミック材料何れもアパタイト、燐酸カルシウムの何れ
かであることがあり得るが、この場合は骨は第２被覆層
の内部迄侵入し、骨との接合力の最も強いセラミック被
覆インプラントとなる。併し青年者用等極めて長期間生
体に埋設される場合は骨とＷ 、 Ｍｏ又はＧｅが直接
接触することとなるが、第２被覆層又は第３被覆層に燐
酸カルシウムを用いる場合はこの燐酸カルシウムではな
いセラミック層が骨と金属とのバリヤ一層として働き、
極めて安全なものとなる。As an embodiment of the present invention, the ceramic material of the second coating layer, the ceramic material of the third coating layer, and the ceramic material of the fourth coating layer may all be apatite or calcium phosphate. In this case, the bone penetrates into the second covering layer, resulting in a ceramic-covered implant with the strongest bonding force with the bone. However, when implanted in a living body for a very long period of time, such as for young people, W, Mo, or Ge will come into direct contact with the bone, but if calcium phosphate is used for the second or third coating layer, this phosphoric acid A non-calcium ceramic layer acts as a barrier between bone and metal,
It will be extremely safe.
この発明を義歯装着用歯科インプラントに用いたものの
形状を第２図に示す。図中（８）は、歯科用に用いられ
るセラミック被覆インプラントであり、顎骨ＯＱに埋設
されたセラミック被覆インプラント（８）の脚部０■も
上記同様に１インプラント基体（２）の上に第１被佼層
（３）、第２被覆層（４）及び第３被覆層（５）、第４
被覆層（６）を積層しているものである。特に、脚部（
６）が骨（１（１１中に埋設されるとき、第４被覆層（
６）がアパタイトあるいはリン酸カルシウムにより構成
されるため、前転化により一体となシ、耐久性と同時に
強度も高くなるものであり、第１被覆層を金属で被覆し
、第２被覆層を金属及びセラミックとするため、第３被
覆層のセラミック材と強固に接合でき、第３被覆層と第
４被覆層はどちらもセラミックであるため親和性が高く
、又第４被覆層は骨と親和性が高く、生体内で骨に転化
するので、結局、基体金属から前進が強固に結合でき、
且つ生体為害性もないものである。FIG. 2 shows the shape of a dental implant in which this invention is applied to a denture. In the figure, (8) is a ceramic-coated implant used for dentistry, and the leg 0■ of the ceramic-coated implant (8) embedded in the jawbone OQ is also placed on the first implant base (2) in the same manner as above. Covering layer (3), second coating layer (4), third coating layer (5), fourth
A covering layer (6) is laminated thereon. Especially the legs (
When the bone (6) is embedded in the bone (1 (11), the fourth covering layer (
6) Since it is composed of apatite or calcium phosphate, it becomes one piece by pre-conversion, and has high durability and strength.The first coating layer is coated with metal, and the second coating layer is made of metal and ceramic. Therefore, it can be firmly bonded to the ceramic material of the third coating layer, and since both the third coating layer and the fourth coating layer are made of ceramic, they have a high affinity, and the fourth coating layer has a high affinity with bone. , because it converts into bone in the living body, the base metal can be firmly bonded to the base metal.
Moreover, it is not harmful to living organisms.
（発明の効果）
以上のとおり、この発明はインプラント基体に用いられ
る生体金属から有害イオンの溶出を阻止し、生体親和性
に著しく富んだセラミックとの結合をより強固なものと
し、長期間使用できる生体用インプラントが得られると
いう優れた効果をもつものである。(Effects of the Invention) As described above, the present invention prevents the elution of harmful ions from the biometal used for the implant base, strengthens the bond with the ceramic that is extremely biocompatible, and enables long-term use. This has the excellent effect of providing a biological implant.
第１図は、整形外科等に用いられるセラミック被覆イン
プラントの断面図であり、第２図は歯科用に用いられる
セラミック被覆インプラントの取付状態を示す断面図で
ある。第３図はインプラントの積層状態を示す断面図で
ある。
１．８・・・セラミック被覆インプラント、２・・・イ
ンプラント基体、３・・・第１被覆層、４・・・第２被
覆層、５・・・第３被覆層、６・・・第４被覆層、７・
・・骨頭部、９・・・歯肉、１０・・・顎骨、１２・・
・脚部、１３・・・ステム、１４・・・セラミック粉、
１５・・・金ｓｍａ層。
特許出願人 代理人弁理士 藤木三幸
第１図
第２図FIG. 1 is a cross-sectional view of a ceramic-coated implant used in orthopedic surgery, etc., and FIG. 2 is a cross-sectional view showing a state in which the ceramic-coated implant used in dentistry is installed. FIG. 3 is a sectional view showing the stacked state of the implant. 1.8... Ceramic coated implant, 2... Implant base, 3... First coating layer, 4... Second coating layer, 5... Third coating layer, 6... Fourth Covering layer, 7.
... Bone head, 9... Gums, 10... Jaw bone, 12...
・Legs, 13... Stem, 14... Ceramic powder,
15... Gold SMA layer. Patent applicant Representative patent attorney Miyuki Fujiki Figure 1 Figure 2
Claims (3)
金属よりなるインプラント基体の表面に生体為害性の少
ない金属を被覆した第１被覆層を設け、次にこの第１被
覆層の上に、生体為害性の少ない金属を被覆したセラミ
ツク粉末を溶着して形成する第２被覆層を設け、この第
２被覆層上に、セラミツク粉末と連なるセラミツク材よ
りなる第３被覆層を設けその上にアパタイト又はリン酸
カルシウムより形成する第４被覆層を積層してなるセラ
ミツク被覆インプラント。(1) A first coating layer coated with a metal that is less harmful to the body is provided on the surface of the implant base made of biometal such as stainless steel, Co-Cr alloy, Ti alloy, etc., and then on this first coating layer, A second coating layer is formed by welding ceramic powder coated with a metal that is less harmful to living organisms, and on this second coating layer, a third coating layer made of a ceramic material connected to the ceramic powder is provided, and apatite is applied on top of the third coating layer. Or a ceramic-coated implant formed by laminating a fourth coating layer made of calcium phosphate.
ｅよりなるものとした特許請求の範囲第１項記載のセラ
ミツク被覆インプラント。(2) The metals of the first coating layer and the second coating layer are Mo, W, and G.
The ceramic-coated implant according to claim 1, comprising e.
Ｎ＿４，ＺｒＯ＿２，ＳｉＣ，ＴｉＷよりなるものとし
た特許請求の範囲第１項と第２項に記載のセラミツク被
覆インプラント。(3) The ceramic material of the second coating layer is alumina, Si_3
A ceramic-coated implant according to claims 1 and 2, which is made of N_4, ZrO_2, SiC, TiW.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61307849A JPH0622576B2 (en) | 1986-12-25 | 1986-12-25 | Ceramic coated implant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61307849A JPH0622576B2 (en) | 1986-12-25 | 1986-12-25 | Ceramic coated implant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63160665A true JPS63160665A (en) | 1988-07-04 |
| JPH0622576B2 JPH0622576B2 (en) | 1994-03-30 |
Family
ID=17973918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61307849A Expired - Lifetime JPH0622576B2 (en) | 1986-12-25 | 1986-12-25 | Ceramic coated implant |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0622576B2 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01317447A (en) * | 1988-06-20 | 1989-12-22 | Permelec Electrode Ltd | Bioaffinity material-jointed body and production thereof |
| JPH02503757A (en) * | 1987-06-15 | 1990-11-08 | イリ‐ウルポ，アンティ | Implants for replacing parts of teeth or bone tissue |
| WO1992014422A1 (en) * | 1991-02-20 | 1992-09-03 | Tdk Corporation | Composite bio-implant and production method therefor |
| FR2688139A1 (en) * | 1992-03-06 | 1993-09-10 | Zimmer Sa | NEW COATING FOR PROTHETIC SYSTEM. |
-
1986
- 1986-12-25 JP JP61307849A patent/JPH0622576B2/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02503757A (en) * | 1987-06-15 | 1990-11-08 | イリ‐ウルポ，アンティ | Implants for replacing parts of teeth or bone tissue |
| JPH01317447A (en) * | 1988-06-20 | 1989-12-22 | Permelec Electrode Ltd | Bioaffinity material-jointed body and production thereof |
| WO1992014422A1 (en) * | 1991-02-20 | 1992-09-03 | Tdk Corporation | Composite bio-implant and production method therefor |
| FR2688139A1 (en) * | 1992-03-06 | 1993-09-10 | Zimmer Sa | NEW COATING FOR PROTHETIC SYSTEM. |
| US5543209A (en) * | 1992-03-06 | 1996-08-06 | Zimmer, Inc. | Surface coating for prosthesis system containing HA/TCP composition |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0622576B2 (en) | 1994-03-30 |
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