JPS63119408A - Cosmetic - Google Patents

Abstract

PURPOSE:To obtain a cosmetic, capable of imparting extensibility, smoothness and moistness to the skin and having feeding of use in which the skin smoothes with time, by blending a starch hydrolyzing enzyme in a powdery state. CONSTITUTION:A cosmetic obtained by containing 0.001-80wt% powdery biological formulation prepared by freeze drying a starch hydrolyzing enzyme, e.g. alpha-amylase, beta-amylase, glucoamylase, isoamylase or pullulanase. The cosmetic, if necessary, may contain a dried cosmetic base normally used in cosmetics, e.g. humectant, water-soluble high polymer, surfactant, germicide and preservative, hydrophilic inorganic powder, coloring matter, vitamin, perfume, hormone, etc. In use, the cosmetic is dissolved in water and used.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention is characterized by containing a starch-degrading enzyme, which imparts elasticity, smoothness, and moisture to the skin.
The present invention relates to a novel cosmetic that makes the skin smooth and smooth over time.

[Conventional technology]

Saccharides obtained by hydrolysis with starch-degrading enzymes such as amylase have been commonly used in cosmetics as moisturizing agents, but silver powder-degrading enzymes play an intermediary role in producing the saccharides. There is no example of a combination of the following.
Moreover, there are no examples of it being blended into cosmetics without its activity.

[Problem that the invention seeks to solve]

In view of the above circumstances, the present inventors have conducted intensive research to obtain active cosmetics. As a result, the present inventors have developed a new cosmetic containing silver powder degrading enzyme, which is powder-like and usually contains freeze-dried starch degrading enzyme. It has been found that the above-mentioned drawbacks can be solved by using the present invention, and the present invention provides a unique effect that gives elasticity, smoothness, and moisture to the skin, and makes the skin smooth and smooth over time. I was able to complete it.

[Means for solving problems]

That is, the present invention is a cosmetic composition characterized by containing a starch degrading enzyme, and the cosmetic composition of the present invention usually uses a silver powder degrading enzyme in powder form.

The starch degrading enzyme used in the present invention includes α-enzyme number: 3.2.1.1, commonly used core: α-amylase, manufacturing company: Chomen Sangyo, Tenmoto Sangyo, Daiwa Kasei, Toa Koso, Hankyu Kyoei, Examples include Toyobo, Ueda Chemical, and Meiji Seika.

Origins include Aspergillus aspergillus, Bacillus subtilis, and pig pancreas.

For example, currently commercially available high-purity reagent-use Bacillus subtilis and liquefied α-amylase include crystal preparations manufactured by Nagashio Sangyo, crystal preparations manufactured by Daiwa Kasei, and freeze-dried preparations manufactured by Seikagaku Corporation.

Enzyme numbers: 3.2, 1.2, regular users: β-amylase, manufacturers such as Ni-Amano Pharmaceutical and Nagashio Sangyo.

It is obtained from plants such as malt, ungerminated barley, sweet potato, and soybeans. For example, currently commercially available high-purity β
-Amylase includes soybean β-amylase manufactured by Nagase Seikagaku Kogyo.

Enzyme number: 3.2.1.3, Regular user: Glucoamylase, Amyloglucosidase, Manufacturer: Nitamano Pharmaceutical, Cho'rlA Sangyo, Hankyu Kyoei Matsutani Chemical, Shinnihon Chemical, Narita Pharmaceutical, Kyowa Hakko, Sankyo, Yamato Examples include Kasei, Tanabe Pharmaceutical, Toyobo, Nihon Shisho, and Fujisawa Pharmaceutical. Glucoamylase preparation is Rhizopus niveas (Rhizopus n.
1veus), Rhizopus deremer (Rhizopu
s delemar), Aspergillus niger (As
pergillus niger), Aspergillus oryzae
,) Trichoderma viride (Trichoderma vi)
ride), Hibocreabelphata (Ilypoc)
eapelfaLa), Mucorlobuxianas (
Mucor r.

vxianus), Coniopholaacelebae (C
onioph.

ra cerebella), Aspergillus awamori (Aspergillus awamori)
, Aspergillus
usami), Aspergillus sitei (8 sp.
ergillus 5aitoi), Penicillium (
Penicillium ), Neurospora (Ne
urospora), Monascus (Monascus)
), Retinus, etc. For example, commercially available glucoamylase with extremely high purity is Zopsniveas (Rh) manufactured by Nagashio Sangyo.
Rhizopus n1veus), Rhizopus n1veus manufactured by Seikagaku Corporation
\Rhizopus deremer made by Toyobo Co., Ltd.
delemar) etc. Similar reagent kits include Diacolor GC (Ono Pharmaceutical Co., Ltd., Autopunk A,
Glucose (Boehringer Mannheim), Glucase (
Glucose B Test 1-Wako (manufactured by Wako Junffi), Unitest Glucose (manufactured by Amco), Glucose Labid (manufactured by Nippon Roche), Determiner GL
-R (manufactured by Kyowa Hakko), Testomer C Glucose Mono (manufactured by Hoechst), and Borazyme (Kyoto Dai-Kagakuso).

Enzyme number: 3.2. L, 9, common name: isoamylase, α-1,6-glucosidase, manufactured by Nibayashibara Biochemical Research Institute, etc. The origin is Pseudomonas amyloderamosa (Pseudomonas amy
loderamosa) 5B15, Cytophaga (
Cytopbaga), Flavobacterium (Fla
vobacterium), Bacillus
us), Amyloliq faciens
uefaciens) Furthermore, it is also found in potato tubers and the like. For example, commercially available products include Pseudomonas asiloderamosa manufactured by Hayashibara Biochemical Research Institute.
onas amyloderamosa).

In addition, Aerobacter aerogenes (^eroba
Pullulanase has been discovered as an enzyme that degrades pullulan from a strain of C. cter aerogenes.

For example, commercially available products include Aerobacter aerogenes (Ae
robacter aerogenes) (manufactured by Hayashibara Biochemical Research Institute).

In addition, as a completely new pullulan-degrading enzyme, Aspergillus niger
Isopullulanase has been discovered from

One or more types of powdered biological preparations obtained by freeze-drying these enzymes are arbitrarily selected. The blending amount is preferably 0.001 to 80% by weight.

It may cause burns.

In addition to the above-mentioned essential ingredients, the cosmetic composition of the present invention may optionally contain a dry cosmetic base. As cosmetic bases, the following are preferred, which are dissolved or dispersed in water or cosmetics added at the time of use.

For example, as a humectant, polyethylene glycol 40
00 to polyethylene glycol 20,000, powdered Ravid, glucose, sucrose, lactose, xylitol, sorbitol, mannitol, maltitol, cyclodextrin, crown glucan, and the like.

Water-soluble polymer compounds include guar gum, locust bean gum, quince seed, carrageenan, galactan, gum arabic, tragacanth, pectin, mannan,
Starch, xanthan gum, dextrin, succinoglucan, curdlan, gelatin, albumin, collagen, methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose, methylhydroxypropylcellulose, soluble starch, carboxymethylstarch, methylstarch, propylene alginate Examples include glycol, alginate, polyvinyl alcohol, polyvinylpyrrolidone, polyvinyl methyl ether, carboxyvinyl polymer, sodium polyacrylate, ethylene oxide, propylene oxide block copolymer, bentonite, laponite, finely divided silicon oxide, and colloidal alumina.

Examples of surfactants include anionic surfactants such as fatty acid soaps, ether carboxylic acids and their salts, alkanesulfonates, α-olefin sulfonates, higher fatty acid ester sulfonates, dialkyl sulfosuccinates, and higher fatty acid amides. Sulfonates, alkylaryl sulfonates, higher alcohol sulfate ester salts, secondary higher alcohol sulfate ester salts, alkyl and alkylaryl ether sulfate ester salts, sulfate ester salts of glycerin fatty acid esters, sulfate ester salts of higher fatty acid alkylolamides , phosphoric acid ester salts, amino acid or collagen hydrolyzate and higher fatty acid condensates, etc.; as cationic surfactants, alkylamine salts, polyamines and alkanolamine fatty acid derivatives, alkyl quaternary ammonium salts, cyclic quaternary ammonium salts, etc. Examples of amphoteric surfactants include carboxylic acid type, sulfuric acid ester type, sulfonic acid type, and phosphoric acid ester type. Examples of the nonionic surfactant include polyhydric alcohol ester type surfactants, fatty acid glycerin esters, sucrose fatty acid esters, and the like. Examples of the antioxidant include nordihydroguaiaretic acid, propyl gallate, erythorbic acid, sodium erythorbate, and the like.

Examples of sterilizing and preservative agents include sodium benzoate, sodium salicylate, sodium dehydroacetate, and methyl paraoxybenzoate.

Furthermore, hydrophilic inorganic powder, amino acids, pigments, vitamins,
Ingredients commonly used in cosmetics, such as fragrances, hormones, and drugs, can be blended.

It has the effect of giving the skin a feeling of smoothness and smoothness over time.

〔Example〕

Examples and comparative examples are given below to specifically clarify the present invention. The present invention is not limited thereby. How to use: Dissolve in water.

The blending amount is %.

(Manufacturing method) ① to ② were sealed in a polyethylene bag and mixed by hand until homogeneous to obtain essence powder.

(How to use) The cosmetic of the present invention is divided into 0.5 to 2 g packets, and when used, it is dispersed in about 5 to 10 times the amount of water and applied to the entire face.

(Effect) Table 1 shows Examples 1, 2.3, 4, 5.6.7. Comparative example 1
The results of a test on the feeling of use when applied to the faces of 20 beauty technicians are shown below. The method was to apply a specific product to the left half of the face and a comparative product to the right half of the face, and the results of the comparison were summarized as a self-reported usability evaluation for each.

The criteria for judgment are as follows.

1. Spreadability on the skin ◎: More than 80% of the beauty technicians were satisfied that the spreadability on the skin was good compared to the comparative example.

○: More than 60% of beauty technicians were satisfied that the product spread well on the skin compared to the comparative example.

Δ: More than 40% of the beauty technicians were satisfied that the product spread well on the skin compared to the comparative example.

×: Compared to the comparative example, less than 40% of the beauty technicians were satisfied that the product spread well on the skin.

2. Smoothness on the skin ◎: More than 80% of the beauty technicians were satisfied that the skin was smoother than the comparative example.

O: More than 60% of the beauty technicians were satisfied that their skin became smoother compared to the comparative example.

Δ: More than 40% of the beauty technicians were satisfied that their skin became smoother than the comparative example.

×: Compared to the comparative example, less than 40% of the beauty technicians were satisfied that their skin had become smoother.

3. Moistness and freshness to the skin ◎: More than 80% of the beauty technicians were satisfied that the skin was moist and fresh compared to the comparative example.

○: More than 60% of the beauty technicians were satisfied that their skin felt moist and fresh compared to the comparative example.

△: More than 40% of the beauty technicians were satisfied that the skin became moist and fresh compared to the comparative example.

×: Compared to the comparative example, less than 40% of the beauty technicians were satisfied that their skin felt moist and fresh.

4. Changes in skin over time ◎: Compared to the comparative example, more than 80% of the beauty technicians were satisfied that their skin had become smoother over time.

○: Compared to the comparative example, more than 60% of the beauty technicians were satisfied that their skin became smoother and smoother over time.

Δ: Compared to the comparative example, more than 40% of the beauty technicians were satisfied that their skin had become smoother and smoother over time.

×: Compared to the comparative example, less than 40% of the beauty technicians were satisfied that their skin had become smoother over time.

(Margin below) Chapter 1 Table

Claims (1)

[Claims] A cosmetic product characterized by containing a starch-degrading enzyme.