JPS628187B2 - - Google Patents
Info
- Publication number
- JPS628187B2 JPS628187B2 JP57004010A JP401082A JPS628187B2 JP S628187 B2 JPS628187 B2 JP S628187B2 JP 57004010 A JP57004010 A JP 57004010A JP 401082 A JP401082 A JP 401082A JP S628187 B2 JPS628187 B2 JP S628187B2
- Authority
- JP
- Japan
- Prior art keywords
- human body
- applicator
- microwave
- cooling water
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000498 cooling water Substances 0.000 claims description 19
- 238000001816 cooling Methods 0.000 claims description 13
- 238000010438 heat treatment Methods 0.000 claims description 8
- 230000005855 radiation Effects 0.000 claims description 6
- 238000011282 treatment Methods 0.000 claims description 5
- 239000004809 Teflon Substances 0.000 description 11
- 229920006362 Teflon® Polymers 0.000 description 11
- 201000011510 cancer Diseases 0.000 description 9
- 206010028980 Neoplasm Diseases 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 4
- 210000002414 leg Anatomy 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- 125000006850 spacer group Chemical group 0.000 description 3
- 230000007423 decrease Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
Landscapes
- Radiation-Therapy Devices (AREA)
Description
【発明の詳細な説明】
本発明は加温治療用マイクロ波放射器、特に生
体内部の温度をマイクロ波による誘電損を利用し
て上昇させるマイクロ波放射器に関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a microwave radiator for heating therapy, and particularly to a microwave radiator that increases the temperature inside a living body by utilizing dielectric loss caused by microwaves.
癌等の悪性腫瘍は43〜45℃で一定時間加温する
と癌細胞が死滅したり、他の治療法がより効果的
に行えることが知られている。 It is known that heating malignant tumors such as cancer at 43 to 45°C for a certain period of time kills cancer cells and makes other treatments more effective.
このため、人体内部の患部を効果的に加温する
装置として、マイクロ波アプリケータを用い、こ
のアプリケータから人体内部の患部に向けマイク
ロ波を放射し、このマイクロ波による誘電損を利
用して患部の温度を上昇させる装置が提案されて
いる。しかし、同一強度のマイクロ波によつて引
き起こされる生体内部の誘電損特性は生体の深さ
にかかわりなくほぼ一定と考えられるので、前記
装置によりマイクロ波を用いて人体の加温を行う
場合、人体内部の温度は人体表面から深くなるに
従い指数関数的に減少する。従つて、人体内の患
部を43〜45℃程度に加温するためには、患部より
浅い部分は不必要にそれ以上の温度に加温され、
健全な組織も破壊されてしまい好ましくない。 For this reason, a microwave applicator is used as a device to effectively heat the affected area inside the human body, and microwaves are emitted from this applicator toward the affected area inside the human body, and the dielectric loss caused by this microwave is used. Devices have been proposed that increase the temperature of the affected area. However, the dielectric loss characteristics inside a living body caused by microwaves of the same intensity are considered to be almost constant regardless of the depth of the living body. The internal temperature decreases exponentially as you get deeper from the surface of the human body. Therefore, in order to heat the affected part of the human body to about 43 to 45°C, parts shallower than the affected part are unnecessarily heated to a higher temperature.
Healthy tissues are also destroyed, which is undesirable.
本発明は前述した課題に鑑みなされたもので、
その目的は人体表面の温度を上げることなく人体
の所定深さに存する患部、例えば癌等の悪性腫瘍
を効果的に加温することの可能な加温治療用マイ
クロ波放射器を提供することにある。 The present invention was made in view of the above-mentioned problems,
The purpose is to provide a microwave radiator for heating treatment that can effectively heat an affected area at a predetermined depth of the human body, such as a malignant tumor such as cancer, without raising the temperature of the surface of the human body. be.
上記目的を達成するため、本発明はマイクロ波
を人体内に放射し体内を加温するマイク波アプリ
ケータと、このアプリケータのマイクロ波放射面
より少し大きな面積から成りかつ冷却水の流入口
及び流出口が形成されたシートバツグを有しこの
シートバツグをマイクロ波放射面に配設してアプ
リケータに一体に取り付け前記流入口及び流出口
から冷却水を循環させる冷却装置と、を備え、人
体表面の温度を前記冷却水の作用により調整する
ことを特徴とする。 In order to achieve the above object, the present invention comprises a microwave applicator that radiates microwaves into the human body to heat the inside of the human body, and a microwave applicator that has an area slightly larger than the microwave radiation surface of this applicator and has a cooling water inlet and a cooling device for circulating cooling water from the inflow port and the outflow port, the sheet bag having an outflow port formed therein, and a cooling device for disposing the seat bag on a microwave emitting surface and integrally attaching it to the applicator; It is characterized in that the temperature is adjusted by the action of the cooling water.
次に本発明の好適な実施例を説明する。 Next, preferred embodiments of the present invention will be described.
第１図はマイクロ波放射器の外観説明図であ
る。図において、１０は同軸ケーブル１２の端部
にコネクタ１４を介して接続されたマイクロ波ア
プリケータであり、本実施例においては、ほぼ円
筒形に形成されている。このアプリケータ１０は
コネクタ１４の反対側が開口されており、この開
口部から人体に向けマイクロ波を放射する構造と
なつている。１６は冷却装置としてのテフロンシ
ートバツグであり、アプリケータ１０の開口部す
なわちマイクロ波放射面に位置して配置され、使
用に際しては人体表面に密着しその内部に流入口
１８から流れ込み流出口２０から流れ出す冷却水
により人体表面を強制的に冷却する。本実施例に
おいては、アプリケータ１０とシートバツグ１６
とは別体に形成されているため、使用に際してア
プリケータ１０と人体との間にシートバツグ１６
を位置させるスペースを確保し、更にアプリケー
タ１０を位置決めしアプリケータ１０のマイクロ
波放射方向を設定するスペーサ２２が設けられて
いる。このスペーサ２２はアプリケータ１０に固
定された支持板２４と、この支持板２４の両端に
設けられた一対の脚部２６とから成り、この脚部
２６はその先端の人体と当接する位置にゴムカバ
ー２８が設けられており、またその高さも支持板
２４との螺合位置を変えることにより任意に調整
することができる。 FIG. 1 is an explanatory diagram of the external appearance of a microwave radiator. In the figure, 10 is a microwave applicator connected to the end of a coaxial cable 12 via a connector 14, and in this embodiment, it is formed into a substantially cylindrical shape. This applicator 10 has an opening on the opposite side of the connector 14, and is configured to radiate microwaves toward the human body from this opening. Reference numeral 16 denotes a Teflon sheet bag as a cooling device, which is placed at the opening of the applicator 10, that is, the microwave radiation surface, and when in use, it is brought into close contact with the surface of the human body, and water flows into the bag from the inlet 18 and the outlet 20. The cooling water that flows out forcibly cools the surface of the human body. In this embodiment, the applicator 10 and the seat bag 16 are
Since it is formed separately from the applicator 10, a seat bag 16 is placed between the applicator 10 and the human body during use.
A spacer 22 is provided to secure a space for positioning the applicator 10, to position the applicator 10, and to set the microwave radiation direction of the applicator 10. This spacer 22 consists of a support plate 24 fixed to the applicator 10, and a pair of legs 26 provided at both ends of this support plate 24. The legs 26 have rubber bands at their tips at positions where they come into contact with the human body. A cover 28 is provided, and its height can be arbitrarily adjusted by changing the screwing position with the support plate 24.
本発明は以上の構成から成り、次にその作用を
説明する。 The present invention has the above configuration, and its operation will be explained next.
まず本実施例において、冷却装置すなわちテフ
ロンシートバツグ１６を用いずアプリケータ１０
から直接人体内にマイクロ波を放射した場合を考
える。一般に人体内でマイクロ波によつて引き起
こされる誘電損はその深さにかかわりなくほぼ一
定であると仮定されるので、マイクロ波による体
内の加温は人体表面から次式に示す如く指数関数
的に減少する。 First, in this embodiment, the applicator 10 is
Consider the case where microwaves are radiated directly into the human body. Generally, it is assumed that the dielectric loss caused by microwaves inside the human body is almost constant regardless of its depth, so heating inside the body due to microwaves increases exponentially from the surface of the human body as shown in the following equation. Decrease.
Ｔ（ｔ）＝To・ｅ-〓t ……(1)
ｔ：人体表面からの深さ
α：人体の高周波特性によつて決まる定数
To：人体表面の皮膚温度
上記(1)式をグラフで図示すると、第２図中ａで
示される。しかし、癌等の悪性腫瘍の治療には、
人体内の所定深さに位置する患部を43〜45℃まで
加温せねばならず、そのためには、人体表面の温
度Toは43〜45℃以上となり、この部分の組織が
破壊されてしまうおそれがある。従つて、患部の
温度を十分に上げる一方で、マイクロ波が照射さ
れる、人体表面の温度を下げ、健康な組織の破壊
を防止する必要がある。 T(t)=To・e - 〓 t ...(1) t: Depth from the human body surface α: Constant determined by the high frequency characteristics of the human body To: Skin temperature on the human body surface Expression (1) above in a graph To illustrate, it is indicated by a in FIG. However, for the treatment of malignant tumors such as cancer,
The affected area located at a predetermined depth within the human body must be heated to 43 to 45 degrees Celsius, and in order to do so, the temperature of the surface of the human body To exceeds 43 to 45 degrees Celsius, and there is a risk that the tissue in this area may be destroyed. There is. Therefore, it is necessary to sufficiently raise the temperature of the affected area while lowering the temperature of the surface of the human body, which is irradiated with microwaves, to prevent destruction of healthy tissue.
そこで、本発明においては、スペーサ２２の脚
部２６の高さを調整し、アプリケータ１０の開口
部と人体表面との間にテフロンシートバツグ１６
を位置させ、更にこのテフロンシートバツグ１６
内に冷却水を常時流入・流出させることにより、
アプリケータ１０から人体に向け放射されるマイ
クロ波によつて加温される人体表面を冷却する。
このように、シートバツグ１６内に冷却水を流
入・流出させることにより得られる人体内部にお
ける加温特性は第２図中曲線ｂで示される。同図
からも明らかなように、本発明によれば、人体表
面の温度上昇を防ぎ体内の患部を効果的に加温す
ることができる。 Therefore, in the present invention, the height of the legs 26 of the spacer 22 is adjusted, and a Teflon sheet bag 16 is placed between the opening of the applicator 10 and the human body surface.
and then this Teflon sheet bag 16
By constantly letting cooling water flow in and out,
The surface of the human body heated by the microwaves emitted from the applicator 10 toward the human body is cooled.
The heating characteristic inside the human body obtained by causing the cooling water to flow in and out of the seat bag 16 in this way is shown by curve b in FIG. As is clear from the figure, according to the present invention, it is possible to prevent the temperature rise on the surface of the human body and effectively warm the affected area within the body.
本実施例においては、シートバツグ１６内を通
過する冷却媒体として水を用いた。これは水の誘
電損特性が人体の誘電損特性に近く、更にその高
周波特性も似ているため、水と人体との界面で生
ずるマイクロ波の反射は、空気冷却を行つた場合
に空気と人体との界面で生ずるマイクロ波の反射
に比して極めて少ないと期待されるからである。
しかし、このようなマイクロ波のロスが問題とな
らないならば、他の種類の冷却媒体を用いること
も可能である。 In this embodiment, water was used as the cooling medium passing through the seat bag 16. This is because the dielectric loss characteristics of water are close to those of the human body, and their high frequency characteristics are also similar, so the reflection of microwaves that occurs at the interface between water and the human body is This is because it is expected to be extremely small compared to the microwave reflection that occurs at the interface with the
However, if such microwave loss is not a problem, other types of cooling media can also be used.
うさぎの大腿部の筋肉を用いた動物実験によれ
ば、シートバツグ１６内に15℃の冷却水を毎分
125c.c.流しつつアプリケータ１０から50Wのマイ
クロ波を４分間上記筋肉に放射した場合、該筋肉
の皮膚温度Toを40℃に保ちつつ筋肉内の深さ14
mmの個所を45℃にまで加温することが確認されて
いる。 According to an animal experiment using rabbit thigh muscles, cooling water at 15°C was poured into the seat bag 16 every minute.
When 50W microwaves are radiated from the applicator 10 to the above muscle for 4 minutes while flowing 125c.c., the skin temperature of the muscle is maintained at 40℃ while the intramuscular depth 14
It has been confirmed that it can heat up to 45℃ at a location of mm.
なお本発明において留意すべき点は、シートバ
ツグ１６内等を流れる冷却水によりアプリケータ
１０から放射されるマイクロ波のエネルギの何パ
ーセントかが消費されてしまうことである。実験
によれば、厚さ５mmのシートバツグ１６内に24℃
の冷却水を毎分100c.c.流し、25.9℃の水を負荷と
して加温した場合には、照射したエネルギの50％
が冷却水により消費されることが確認されてい
る。従つて、体内の患部を所定温度にまで加温す
るためには、冷却装置内におけるマイクロ波のエ
ネルギ損失を、考慮し、この損失分だけエネルギ
を増量してマイクロ波を放射する必要がある。 In the present invention, it should be noted that some percent of the microwave energy emitted from the applicator 10 is consumed by the cooling water flowing inside the seat bag 16 and the like. According to experiments, a temperature of 24℃ was found in a sheet bag 16 with a thickness of 5mm.
When cooling water flows at 100 c.c./min and is heated with water at 25.9°C as a load, 50% of the irradiated energy is used.
has been confirmed to be consumed by cooling water. Therefore, in order to heat the affected area within the body to a predetermined temperature, it is necessary to take into account the energy loss of the microwave within the cooling device and increase the energy by this loss before emitting the microwave.
付言すれば、アプリケータ１０から放射される
マイクロ波エネルギの大きさと、シートバツグ１
６内の冷却水の温度を調節することにより、体内
の深さ方向の温度分布を自由に調整することがで
きる。 In addition, the magnitude of the microwave energy radiated from the applicator 10 and the size of the sheet bag 1
By adjusting the temperature of the cooling water inside the body, the temperature distribution in the depth direction inside the body can be freely adjusted.
また前記実施例においては、アプリケータと冷
却装置とを別体に形成したマイクロ波放射器を例
にとり説明した。しかし、本発明はこれに限ら
ず、アプリケータと冷却装置とを一体的に形成す
ることもできる。第３図はこのように形成された
マイクロ波放射器の一実施例を示す側断面図であ
る。図において、冷却装置１６はテフロンシート
バツグとして２枚のテフロンシート３０，３２を
一定間隙をおいてアプリケータ１０の開口部に位
置させ、このシート３０，３２の端部をアプリケ
ータ１０の開口縁部に密封固定し、この２枚のシ
ート３０，３２に囲まれたスペース内に冷却水を
流す構造に形成されている。上記テフロンシート
３０，３２のアプリケータ１０への固定は、Ｏリ
ング３４，３６、断面がほぼＬ字状に形成されア
プリケータ１０の開口外縁部と係合するリング状
のパツキン３８、このパツキン３８を更に内側へ
押圧する弾性支持部材４０とによつて行われる。
まずアプリケータ１０の開口外縁部に形成した凹
溝４２にＯリング３４を嵌合させ、このＯリング
３４とリング状のパツキン３８の内側とで一方の
テフロンシート３０の端部を密封固定する。ここ
において、Ｏリング３４と対向するパツキン３８
の位置には凹溝３８ａを形成しておき、テフロン
シート３０の密封度を向上させている。更に弾性
支持部材４０の内側面にＯリング３６を接着固定
し、このＯリング３６とパツキン３８との間に他
方のテフロンシート３２の端部を密封固定する。
なおＯリング３６と対向するパツキン３８の位置
には凹溝３８ｂが形成され、テフロンシート３２
の密封度を向上させている。そして、このように
支持固定されたテフロンシート３０，３２に囲ま
れるスペースには、パツキン３８に形成された流
入口１８、流出口２０から冷却水が注入・排出さ
れ、前述したように、人体表面の冷却を行う。 Further, in the embodiments described above, a microwave radiator in which the applicator and the cooling device are formed separately has been described as an example. However, the present invention is not limited to this, and the applicator and cooling device can also be formed integrally. FIG. 3 is a side sectional view showing one embodiment of the microwave radiator formed in this manner. In the figure, the cooling device 16 positions two Teflon sheets 30 and 32 as Teflon sheet bags at the opening of the applicator 10 with a certain gap between them, and connects the ends of the sheets 30 and 32 to the opening edge of the applicator 10. The structure is such that cooling water is allowed to flow into the space surrounded by the two sheets 30 and 32. The Teflon sheets 30, 32 are fixed to the applicator 10 by O-rings 34, 36, a ring-shaped gasket 38 whose cross section is approximately L-shaped, and which engages with the outer edge of the opening of the applicator 10. This is done by means of an elastic support member 40 which further presses the inner part of the body.
First, an O-ring 34 is fitted into a groove 42 formed at the outer edge of the opening of the applicator 10, and the end of one Teflon sheet 30 is sealed and fixed between this O-ring 34 and the inside of a ring-shaped packing 38. Here, the gasket 38 facing the O-ring 34
A concave groove 38a is formed at the position , which improves the degree of sealing of the Teflon sheet 30. Furthermore, an O-ring 36 is adhesively fixed to the inner surface of the elastic support member 40, and the end of the other Teflon sheet 32 is sealed and fixed between the O-ring 36 and the packing 38.
Note that a concave groove 38b is formed in the position of the gasket 38 facing the O-ring 36, and the Teflon sheet 32
The degree of sealing has been improved. Cooling water is injected and discharged from the inlet 18 and outlet 20 formed in the packing 38 into the space surrounded by the Teflon sheets 30 and 32 supported and fixed in this manner, and as described above, the cooling water is applied to the human body surface. cooling.
本発明によれば、シートバツグをマイクロ波放
射面のみに設け流入口及び流出口から冷却水を供
給するようにしたので、無駄のない装置により必
要な部分のみあるいは足や手等の各種部位の冷却
を容易に行うことができ、またシートバツグをア
プリケータに一体に取り付けるようにしたので、
冷却装置を患部にセツトする作業を簡略化するこ
とができる。そして、マイクロ波を用いて人体内
に存する患部、例えば癌等の悪性腫瘍を効果的に
加温治療するとともに、マイクロ波によつて引き
起こされる人体表面の温度上昇を冷却装置を用い
て効果的に抑制することにより、人体表層に存す
る健全な組織を破壊することなく体内の患部のみ
を効果的に加温治療することが可能となる。 According to the present invention, since the sheet bag is provided only on the microwave radiation surface and the cooling water is supplied from the inlet and outlet, the cooling water is cooled only to the necessary parts or to various parts such as the feet and hands using an efficient device. The seat bag can be easily attached to the applicator, so
The work of setting the cooling device on the affected area can be simplified. In addition to using microwaves to effectively heat and treat affected areas within the human body, such as malignant tumors such as cancer, we also use cooling devices to effectively reduce the temperature rise on the surface of the human body caused by microwaves. By suppressing the temperature, it becomes possible to effectively heat only the affected area within the body without destroying the healthy tissues existing on the surface of the human body.
第１図は本発明に係る加温治療用マイクロ波放
射器の外観斜視図、第２図は人体内部の加温特性
図、第３図は本発明の他の実施例を示す側断面図
である。
各図中対応する部材には同一符号を付し、１０
はアプリケータ、１６は冷却装置である。
Fig. 1 is an external perspective view of a microwave radiator for heating treatment according to the present invention, Fig. 2 is a heating characteristic diagram inside the human body, and Fig. 3 is a side sectional view showing another embodiment of the present invention. be. Corresponding members in each figure are designated by the same reference numerals, and 10
is an applicator, and 16 is a cooling device.
Claims (1)
マイク波アプリケータと、このアプリケータのマ
イクロ波放射面より少し大きな面積から成りかつ
冷却水の流入口及び流出口が形成されたシートバ
ツグを有しこのシートバツグをマイクロ波放射面
に配設してアプリケータに一体に取り付け前記流
入口及び流出口から冷却水を循環させる冷却装置
と、を備え、人体表面の温度を前記冷却水の作用
により調整することを特徴とする加温治療用マイ
ロ波放射器。1. It has a microwave applicator that radiates microwaves into the human body to heat the inside of the human body, and a seat bag that has an area slightly larger than the microwave radiation surface of this applicator and is formed with an inlet and an outlet for cooling water. a cooling device for disposing a sheet bag on the microwave radiation surface and integrally attaching it to the applicator and circulating cooling water from the inlet and the outlet, and adjusting the temperature of the human body surface by the action of the cooling water. A microwave radiator for heating treatment, which is characterized by:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP401082A JPS58121966A (en) | 1982-01-16 | 1982-01-16 | Microwave discharge device for heat treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP401082A JPS58121966A (en) | 1982-01-16 | 1982-01-16 | Microwave discharge device for heat treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58121966A JPS58121966A (en) | 1983-07-20 |
| JPS628187B2 true JPS628187B2 (en) | 1987-02-21 |
Family
ID=11572996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP401082A Granted JPS58121966A (en) | 1982-01-16 | 1982-01-16 | Microwave discharge device for heat treatment |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58121966A (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59129070A (en) * | 1983-01-10 | 1984-07-25 | 呉羽化学工業株式会社 | Method and apparatus for controlling temperature distribution in living body |
| JPH0632662B2 (en) * | 1985-03-15 | 1994-05-02 | 静夫 水品 | Hyperthermia device |
| JPS6133676A (en) * | 1985-03-31 | 1986-02-17 | 菊地 眞 | Applicator for heat treatment |
| JPS622971A (en) * | 1985-06-29 | 1987-01-08 | 菊地 眞 | Warming apparatus for hyperthermia |
| JPS622970A (en) * | 1985-06-29 | 1987-01-08 | 菊地 眞 | Cooling liquid recirculation apparatus for warming medical treatment |
| JPS622966A (en) * | 1985-06-29 | 1987-01-08 | 菊地 眞 | Applicator for warming medical treatment |
| JPS622968A (en) * | 1985-06-29 | 1987-01-08 | 菊地 眞 | Cooling liquid recirculation apparatus for warming medical treatment |
| JPS62137071A (en) * | 1985-12-10 | 1987-06-19 | フクダ電子株式会社 | Method for treating cancer by irradiation of high frequency |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56109752U (en) * | 1980-01-21 | 1981-08-25 |
-
1982
- 1982-01-16 JP JP401082A patent/JPS58121966A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58121966A (en) | 1983-07-20 |
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