JPS627829B2 - - Google Patents
Info
- Publication number
- JPS627829B2 JPS627829B2 JP6175682A JP6175682A JPS627829B2 JP S627829 B2 JPS627829 B2 JP S627829B2 JP 6175682 A JP6175682 A JP 6175682A JP 6175682 A JP6175682 A JP 6175682A JP S627829 B2 JPS627829 B2 JP S627829B2
- Authority
- JP
- Japan
- Prior art keywords
- chain
- ultrafine particles
- microorganisms
- magnetic
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000011882 ultra-fine particle Substances 0.000 claims description 38
- 244000005700 microbiome Species 0.000 claims description 16
- 230000005684 electric field Effects 0.000 claims description 7
- 239000002245 particle Substances 0.000 description 10
- 239000000696 magnetic material Substances 0.000 description 8
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 238000010353 genetic engineering Methods 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 239000011553 magnetic fluid Substances 0.000 description 1
- 230000005389 magnetism Effects 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- -1 nickel and silver Chemical class 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Description
【発明の詳細な説明】
本発明は、微生物等の流れ制御装置に関する。
一般に、１μ以下の粒子は超微粒子と呼ばれてい
るが、この超微粒子は、近年、それより大きい微
粒子と比べて磁性、光吸収、融点等で特異な性質
を有することが明らかになつてきたので、この性
質を利用した種々の用途が開発されている。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a flow control device for microorganisms, etc.
Generally, particles of 1μ or less are called ultrafine particles, but in recent years it has become clear that these ultrafine particles have unique properties such as magnetism, light absorption, and melting point compared to larger particles. Therefore, various uses have been developed that take advantage of this property.
本発明は、この超微粒子の利用に係り、前記超
微粒子のうちの磁場又は電場の作用を受ける超微
粒子を用いて微生物等の流れを制御する装置を得
ることをその目的とするもので、微生物等が流れ
る流通路の一部に、電場又は磁場の作用を受ける
鎖状超微粒子群を配置し、この近傍に、前記鎖状
超微粒子群を前記微生物等の流れを妨害する方向
に配列する電場又は磁場等の発生装置を設けたこ
とを特徴とする。 The present invention relates to the use of these ultrafine particles, and an object of the present invention is to obtain a device for controlling the flow of microorganisms, etc. by using ultrafine particles among the ultrafine particles that are subjected to the action of a magnetic field or an electric field. A group of chain-like ultrafine particles that is affected by an electric field or a magnetic field is placed in a part of the flow path through which the microorganisms, etc. Alternatively, it is characterized by being provided with a generator for generating a magnetic field or the like.
以下本発明の実施例を図面につき説明する。第
１図において、１は微生物等の増殖等に用いられ
る容器の流通路、２は該流通路１中の後述の鎖状
超微粒子群３の溜部、４Ａ，４Ｂはそれぞれ鎖状
超微粒子群３に磁気力を加えるソレノイド、５
Ａ，５Ｂはそれぞれ鎖状超微粒子群３が溜部２の
近傍から外部へ流出するのを防止するためのソレ
ノイドである。 Embodiments of the present invention will be described below with reference to the drawings. In FIG. 1, 1 is a flow path of a container used for the growth of microorganisms, etc., 2 is a reservoir for a group of chain ultrafine particles 3, which will be described later, in the flow path 1, and 4A and 4B are each a group of chain ultrafine particles. Solenoid that applies magnetic force to 3, 5
A and 5B are solenoids for preventing the chain-like ultrafine particle group 3 from flowing out from the vicinity of the reservoir 2.
前記鎖状超微粒子群３の超微粒子として、１μ
以下0.001μ位までの粒径で、磁場の作用を受け
るものが用いられる。 As the ultrafine particles of the chain-like ultrafine particle group 3, 1μ
Particles with a particle size of up to about 0.001μ and which are subject to the action of a magnetic field are used.
磁場の作用を受ける鎖状超微粒子は、次のよう
にして製造される。容器に封入されたヘリウム等
の不活性ガス中で磁性材を加熱して蒸発させ、蒸
発したその材料の原子は前記ガスで冷却されて凝
結し、次いでこれらが磁場中を通過する時に磁化
する。かくて磁性超微粒子は磁化されて多数個が
鎖状に連結される。この連結粒子数は蒸発早さ、
磁場の大きさ、粒子径等により制御される。 Chain-like ultrafine particles that are subjected to the action of a magnetic field are produced as follows. A magnetic material is heated and evaporated in an inert gas such as helium sealed in a container, and atoms of the evaporated material are cooled and condensed by the gas, and then become magnetized when they pass through a magnetic field. In this way, the magnetic ultrafine particles are magnetized and a large number of them are connected in a chain. This number of connected particles is the rate of evaporation,
Controlled by the magnitude of the magnetic field, particle size, etc.
磁性超微粒子としては、磁性材だけの粒子の他
に、磁性材の芯の外周に非磁性材の皮膜を形成し
たものや非磁性材の芯の外周に磁性材の皮膜を形
成したものが用いられる。 In addition to particles made only of magnetic material, magnetic ultrafine particles include those with a magnetic material core with a non-magnetic material coating around the periphery, and non-magnetic material cores with a magnetic material coating around the periphery. It will be done.
この磁性材の芯の外周に非磁性材の皮膜を形成
した磁性超微粒子は、磁性材だけの粒子がこれと
接触するものを触媒作用で酸化する等悪影響を与
えないように保護膜を前記磁性材粒子に設ける場
合等に好適である。 These magnetic ultrafine particles have a coating of non-magnetic material formed around the outer periphery of the core of magnetic material. It is suitable for cases where it is provided on material particles.
次に第１図示の本発明装置の作動について説明
する。容器の溜部２には、微生物等の流れの制御
態様に応じた所要量の鎖状超微粒子群３を封入す
る。バルブを閉じたのと同じような状態にするに
は、ソレノイド４Ａ，４Ｂに180゜位相のずれた
交流電流を流す。この交流電流の周期は、この電
流による交番磁力と鎖状超微粒子の移動速度がマ
ツチングするものであり、したがつて励磁ソレノ
イドにより鎖状超微粒子は図面の右方向または左
方向に移動する動作をくり返しながら溜部２の中
央に止まるように保つことができ、鎖状超微粒子
はすべてその長さ方向が流れに対して交叉する方
向に配列される。この状態において、流通路１を
流れる微生物は、この鎖状超微粒子群３によつて
その移動を邪魔される。 Next, the operation of the apparatus of the present invention shown in the first figure will be explained. A required amount of chain-shaped ultrafine particles 3 is sealed in the reservoir 2 of the container according to the control mode of the flow of microorganisms, etc. To create the same state as when the valve is closed, apply alternating currents with a phase difference of 180 degrees to solenoids 4A and 4B. The cycle of this alternating current matches the alternating magnetic force caused by this current and the moving speed of the chain-like ultrafine particles. Therefore, the excitation solenoid causes the chain-like ultrafine particles to move to the right or left in the drawing. The chain-shaped ultrafine particles can be kept at the center of the reservoir 2 repeatedly, and all the chain-like ultrafine particles are arranged in a direction that intersects the flow. In this state, the movement of microorganisms flowing through the flow path 1 is hindered by the chain-like ultrafine particle group 3.
バルブを開いたのと同じ状態にするには、ソレ
ノイド４Ａ又は４Ｂのどちらか一方だけを励磁す
る。 To bring the valve into the same state as if it were open, only one of the solenoids 4A or 4B is energized.
かくて鎖状超微粒子群３は磁場の強い方に引き
寄せられるので、溜部２の中央部は非磁性流体が
自由に通り抜けられる。ソレノイド４Ａ，４Ｂは
どちらも励磁しなくてもよく、その場合には、ソ
レノイド５Ａ，５Ｂが励磁してあるので、鎖状超
微粒子群３が外部に流出することがない。 In this way, the chain-shaped ultrafine particle group 3 is attracted toward the stronger magnetic field, so that the non-magnetic fluid can freely pass through the center of the reservoir 2. Neither of the solenoids 4A and 4B needs to be energized; in that case, since the solenoids 5A and 5B are energized, the chain-like ultrafine particle group 3 does not flow out.
鎖状超微粒子の長さ及び太さ（粒子の粒径）を
調節することによつて所定の大きさ以下のものを
流れに乗つて通り抜けさせることができるから、
セパレータとしても働かせることができる。 By adjusting the length and thickness (particle diameter) of the chain-like ultrafine particles, it is possible to allow particles of a predetermined size or smaller to pass along with the flow.
It can also be used as a separator.
また鎖状の磁性超微粒子群の場合には、各鎖状
の磁性超微粒子に磁性超微粒子を有する細胞、微
生物又は酵素を付着させることによつて、細胞、
微生物又は酵素等の流れを阻止し、非磁性の例え
ば微生物の反応生成物を前記鎖状の磁性超微粒子
群の間を通つて流し、微生物等とその反応生成物
とを分離することができる。ソレノイドによる磁
場の発生装置の代りに電場の発生装置を用いた場
合には、電場の作用を受ける鎖状超微粒子が用い
られる。これは、例えば第２図示のように、接触
電位差を発生する２種の金属、例えばニツケル及
び銀の超微粒子の連結鎖から構成され、電気的２
重極子として作用するから、電場中で電気力の作
用を受ける。 In addition, in the case of chain-shaped magnetic ultrafine particles, cells, microorganisms, or enzymes having magnetic ultrafine particles are attached to each chain-shaped magnetic ultrafine particle.
It is possible to prevent the flow of microorganisms, enzymes, etc., and allow non-magnetic, for example, reaction products of microorganisms to flow through the chain-shaped magnetic ultrafine particle group, thereby separating microorganisms, etc. and their reaction products. When an electric field generator is used instead of a magnetic field generator using a solenoid, chain-like ultrafine particles that are affected by the electric field are used. For example, as shown in the second diagram, it is composed of a connected chain of ultrafine particles of two types of metals, such as nickel and silver, which generate a contact potential difference.
Since it acts as a heavy pole, it is affected by the electric force in an electric field.
本明細書では以上の超微粒子の複数個が一列に
連結されたものをすべて「鎖状超微粒子」と名付
けた。 In this specification, all of the above-mentioned ultrafine particles connected in a line are referred to as "chain-like ultrafine particles."
このように本発明によれば、鎖状超微粒子群を
微生物等の流れる流通路の一部に配置し、その近
傍に設けた電場又は磁場等の作用力の発生装置に
よつて鎖状超微粒子群を前記微生物等の流れを妨
害する方向に配列して前記微生物等の流れに対し
バルブ作用又はセパレータ作用をさせたので、微
生物工学、生化学、遺伝子工学等の分野に用いて
有益である。 As described above, according to the present invention, a group of chain-like ultrafine particles is placed in a part of a flow path through which microorganisms, etc. flow, and the chain-like ultrafine particles are The group is arranged in a direction that obstructs the flow of the microorganisms, etc., and acts as a valve or a separator for the flow of the microorganisms, so it is useful in the fields of microbial engineering, biochemistry, genetic engineering, etc.
第１図は本発明の一実施例の説明図、第２図は
本発明の鎖状超微粒子の一例の模型図を示す。
１……流通路、２……溜部、３……鎖状超微粒
子群、４Ａ，４Ｂ，５Ａ，５Ｂ……ソレノイド。
FIG. 1 is an explanatory diagram of an embodiment of the present invention, and FIG. 2 is a schematic diagram of an example of chain ultrafine particles of the present invention. 1... Flow path, 2... Reservoir, 3... Chain-like ultrafine particle group, 4A, 4B, 5A, 5B... Solenoid.
Claims (1)
磁場の作用を受ける鎖状超微粒子群を配置し、こ
の近傍に、前記鎖状超微粒子群を前記微生物等の
流れを妨害する方向に配列する電場又は磁場等の
発生装置を設けたことを特徴とする微生物等の流
れ制御装置。1 A chain-like ultrafine particle group that is affected by an electric field or a magnetic field is placed in a part of the flow path through which microorganisms, etc. flow, and the chain-like ultrafine particle group is arranged in the vicinity of this in a direction that obstructs the flow of the microorganisms, etc. 1. A flow control device for microorganisms, etc., characterized in that it is equipped with a device that generates an electric field or a magnetic field.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6175682A JPS58179483A (en) | 1982-04-15 | 1982-04-15 | Apparatus for controlling flow of microorganism, etc. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6175682A JPS58179483A (en) | 1982-04-15 | 1982-04-15 | Apparatus for controlling flow of microorganism, etc. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58179483A JPS58179483A (en) | 1983-10-20 |
| JPS627829B2 true JPS627829B2 (en) | 1987-02-19 |
Family
ID=13180313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6175682A Granted JPS58179483A (en) | 1982-04-15 | 1982-04-15 | Apparatus for controlling flow of microorganism, etc. |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58179483A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994010299A1 (en) * | 1992-11-05 | 1994-05-11 | Sovmestnoe Rossiisko-Amerikanskoe Predpriyatie 'intermet Engineering' | Method of subjecting a microbiological object to a magnetic field and a device for carrying out the same |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110199972B (en) * | 2019-06-17 | 2024-04-23 | 上海纳朴测控技术有限公司 | Electromagnetic patch assembly, device, system and method for inhibiting aquatic creature breeding |
-
1982
- 1982-04-15 JP JP6175682A patent/JPS58179483A/en active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994010299A1 (en) * | 1992-11-05 | 1994-05-11 | Sovmestnoe Rossiisko-Amerikanskoe Predpriyatie 'intermet Engineering' | Method of subjecting a microbiological object to a magnetic field and a device for carrying out the same |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58179483A (en) | 1983-10-20 |
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