JPS6257566A - Coating agent for treating dermatophytosis - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) This invention relates to a liniment for use in treating athlete's foot.

(Prior Art) For the treatment of athlete's foot, a large number of drugs and therapeutic devices have been developed and are commercially available, but unfortunately there is still no definitive treatment.

By the way, the drugs that are commonly used as drug treatments are:
There are ointments whose main active ingredients are steel or silver.

In addition, there are therapeutic devices that assist the therapeutic effects of drug use. Considering the fact that athlete's foot, i.e., white streak fungus and near red fungus, are likely to occur between toes where there is a lot of moisture due to sweat,
Examples include toe rings that keep the affected area dry at all times.

There are methods that use infrared irradiation, and more recently, physical therapy methods that involve irradiating the affected area with a laser.

However, as mentioned above, there is no guarantee that this will completely cure the condition. An object of the present invention is to provide a liniment as a drug therapeutic agent.

(Problems to be Solved by the Invention) As is well known, the ointments that are most popular as drug therapeutic agents are those that are applied to the affected area.

However, most of the affected areas are between the toes, and therefore the medicinal effect cannot be achieved unless it is thoroughly rubbed between the toes.

Particularly when drugs such as ointments are used, there is a high tendency for the disease to repeat itself in a vicious cycle where the disease does not completely heal, and then it occurs again. This is due to the therapist's treatment attitude, but also because it is an ointment (there is a problem with the permeability of the drug itself).

Needless to point out, athlete's foot is a parasite that mainly infects the stratum corneum of the skin, and therefore cannot be completely cured unless the drug penetrates deep into the stratum corneum. Ointments have low penetration.

What I was able to come up with after changing my perspective was a toe ring that could be used as a therapeutic device. This is effective in removing moisture from the affected area, which can increase the growth of a fungus called athlete's foot.

However, this is of no use unless it is used in combination with the appropriate drug.

Physical therapy using infrared irradiation and Zara's newer therapy using laser irradiation are much more promising than conventional drugs, but laser irradiation is a treatment method that can be used at home. This method requires large-scale equipment, such as equipment, and is not something that everyone can easily use. The drawback is that it requires outpatient treatment.

In any case, conventional drugs and other treatment methods have the disadvantage that, although temporary and superficial cures are possible, it is extremely difficult to achieve complete cure.

(Means for Solving the Problems) Therefore, in order to eliminate the drawbacks of conventional drugs, the present invention uses salicylic acid, which has the highest permeability to the stratum corneum, which is the breeding ground for athlete's foot, and has keratolytic properties. in a weight ratio of 6 to ethyl alcohol, which has hygroscopic, disinfectant, and bactericidal properties.
The aim is to kill the white fungus known as athlete's foot or the scarlet fungus by applying it to the affected area.

(Example) A 6% solution was prepared by dissolving 10 g of salicylic acid in 200 cc of ethyl alcohol (weight ratio ht), and this was applied to the clean affected area twice a day for one week. Coated.

Two to three days after the start of application, the stratum corneum, which is a breeding ground for leprosy fungi, was completely peeled off from the dermis due to the solubility of the salicylic acid contained in the coating agent.

Continue to apply it roughly, and in about a week the epidermis including the stratum corneum will gradually exfoliate, the white fungus will be eradicated, and the epidermis will turn white and heal.

However, the thickness of the stratum corneum varies from person to person. Therefore, although some cases were cured within about one week, it was concluded that continuous application for at least two weeks or more is preferable for complete recovery.

(Effects) As can be understood from the above explanation, the first feature of the topical agent for treating athlete's foot according to the present invention is the solubility of the stratum corneum, which is the breeding ground for athlete's foot, and especially the ability to penetrate the stratum corneum. Since it is made by dissolving salicylic acid in ethyl alcohol, which has disinfectant (sterilizing) and dehydrating properties, it has a higher censoring effect than conventional ointments.

In other words, the permeability of the liniment into the stratum corneum is remarkable;
The patient is on the verge of achieving complete recovery.

The second feature is that since the liniment is liquid, anyone can easily apply it to the affected area.

In other words, compared to conventional ointments or methods using infrared irradiation or laser irradiation, it can be used in the feces and is easy to apply between the toes, which is the affected area, so it is not a sloppy person who does not have to worry about applying it. In addition to its high therapeutic effect, ethyl alcohol's bactericidal and dehydrating properties help wipe out the environment in which athlete's foot breeds, greatly increasing its medicinal efficacy as a therapeutic drug. Combined with the first feature, it is completely effective in treating the problem compared to conventional drugs.

Claims (1)

[Claims] A liniment for treating athlete's foot that contains salicylic acid dissolved in ethyl alcohol at a ratio of 6% by weight.