JPS6241029B2 - - Google Patents

Description

[Detailed Description of the Invention] [Field of Industrial Application] The present invention enables patients who require regular injections, such as diabetic patients, to administer the necessary amount according to a doctor's prescription while carrying a syringe. This invention relates to an automatic injector that can accurately inject an injection drug at regular intervals and also allows additional injections to be made manually as needed.

[Conventional technology]

It has a piston fitted inside the syringe barrel, and a screw rod is rotated through a gear by the drive of a pulse motor.
An automatic syringe that performs injection by converting the rotational movement of the threaded rod into the longitudinal movement of the piston within the syringe barrel is conventionally known (for example, Japanese Utility Model Application No. 52-3292).

[Problem that the invention seeks to solve]

Injections are related to human life, so when automating injections, it is necessary to ensure that the amount of injected drug is accurately specified, and that the time intervals between injections are maintained at precisely specified intervals. In some cases, for example, when injecting insulin, it may be necessary to inject at regular intervals and additionally inject a predetermined amount of the drug at mealtimes. However, conventional auto-injectors are unable to maintain injection time intervals at prescribed intervals or to automatically inject a predetermined amount of drug. Furthermore, when administering additional injections, unless repeated injections are given after a predetermined period of time has elapsed, the amount of drug injected will be too large, which is dangerous. Re-injections must be prevented, but conventional auto-injectors
There was nothing that could deal with this problem.

An object of the present invention is to provide an automatic syringe that solves the above-mentioned problems.

[Means for solving problems]

A first invention of this application is an automatic injector that injects an injection drug by driving the piston of the syringe via a pulse motor, which includes: (1) a first pulse oscillator that generates a reference pulse; a first counter for counting output pulses of a pulse oscillator; an injection time interval memory capable of setting and storing a predetermined injection time interval; and setting of the counted value of the first counter and the injection time interval memory. (2) generating a reference pulse; and (2) generating a reference pulse. a second pulse oscillator that starts counting output pulses of the second pulse oscillator in response to a first signal output from the injection time interval control device that drives the pulse motor; and a first injection dose memory capable of presetting and storing a standard injection dose of the injection drug, and comparing the counted value of the second counter and the set value of the first injection dose memory. a second comparator that outputs a signal to stop driving the pulse motor when the comparison result reaches a predetermined value; (3) starting an additional injection; (4) an additional injection timing control device that outputs a second signal for driving the pulse motor when the additional injection switch is turned on; an injection dose memory, and a third counter that starts counting output pulses of the second pulse oscillator in response to a second signal for driving the pulse motor output from the additional injection timing control device; Said third
a third comparator that compares the counted value of the counter with the set value of the second injection dose memory and outputs a signal to stop driving the pulse motor when the comparison result reaches a predetermined value; Additional injection dose control device equipped.

Further, the second invention of this application is an automatic injector that injects an injection drug by driving the piston of the syringe via a pulse motor, comprising: (1) Standards. a first pulse oscillator that generates pulses, a first counter that counts output pulses of the first pulse oscillator, an injection time interval memory that can set and store a predetermined injection time interval; a first comparator that compares the counted value of the first counter and the set value of the injection time interval memory and outputs a first signal for driving the pulse motor when the comparison result reaches a predetermined value; (2) a second pulse oscillator that generates a reference pulse; a second counter that starts counting output pulses of the pulse oscillator; a first injection dose memory capable of presetting and storing a reference injection dose of the injection drug; and a count value of the second counter. and a second comparator that compares the set value of the first injection dose memory and outputs a signal to stop driving the pulse motor when the comparison result reaches a predetermined value. an injection dose control device; (3) outputting a second signal that drives the pulse motor by turning on an additional injection switch that starts an additional injection, and timing the elapse of a predetermined set time in response to the signal; (4) an additional injection timing control device including a timer that prohibits the output of a second signal for driving the pulse motor even if the additional injection switch is turned on again during time measurement; a second injection dose memory capable of setting and storing the amount in advance; and a second pulse oscillator in response to a second signal for driving the pulse motor output from the additional injection timing control device. a third counter that starts counting output pulses;
a third comparator that compares the count value of the counter with the set value of the second injection dose memory and outputs a signal to stop driving the pulse motor when the comparison result reaches a predetermined value; Additional injection dose control device equipped.

It is characterized by having the following.

[Effect]

The injection time interval control device automatically starts the injection operation at predetermined time intervals preset in memory. The injection operation is stopped by the first injection dose control device when a predetermined injection dose preset in the memory is injected. This makes it possible to accurately inject a predetermined amount of medicine at predetermined intervals.

In addition, there is an additional injection timing control device so that additional injections can be given when the patient desires.When the additional injection switch is turned on, the injection operation starts, and the additional injection dose control device sets the amount in memory in advance. The injection operation is stopped when a predetermined additional injection dose has been injected. The additional injection timing control device includes a timer, and the injection operation is not started even if the additional injection switch is turned on again within a period shorter than a fixed time interval.

〔Example〕

Hereinafter, one embodiment of the present invention will be described using the drawings.

FIG. 1 is a block diagram of an electronic circuit that controls an automatic injector, in which 1 is a first pulse oscillator, 2 is a first counter that counts reference pulses output from the first pulse oscillator, and is a sexagesimal number. It is desirable to have a system that counts by . Reference numeral 4 denotes an injection time interval memory for storing injection time intervals, for example, as described in Korean patent application No.
The thumb wheel switch described in No. 1274 is used. A thumb wheel switch is a switch that has a dial with a dial that can be rotated with a finger as shown in Figure 3.
The turntable with 4 indicates the unit of 10, 7, 8, 9.
The rotating disk marked with indicates a unit of 1. Combining the numbers on these two rotary discs, any number can be stored in memory 4.
It is now set to .

3 is the first comparator and the injection time interval memory 4
The set value of the first counter 2 is compared with the content of the first counter 2, and when the comparison result reaches a predetermined value, that is, when a predetermined time interval set in the memory 4 is reached, the first counter drives a pulse motor that moves the piston of the syringe. The signal is output to the flip-flop 9. This signal also resets the first counter 2 to zero and the counter 2 starts counting again. With the above configuration, injection can be started at every time interval set in the memory 4.

5 is a second pulse oscillator; 6 is a second counter that counts reference pulses output from the second pulse oscillator; 8 is a first injection dose memory that stores the injection dose; Same as Sam
Use a wheel switch, etc. 7 is a second comparator, which compares the set value of the first injection amount memory 8 and the count value of the second counter 6, and when the comparison result reaches a predetermined value, that is, the value set in the memory 8 is set. When a time period corresponding to a predetermined injection amount has elapsed, a signal is output to the flip-flop 9 to stop the pulse motor that moves the piston of the syringe.
With the above configuration, a predetermined injection amount set in the memory 8 is injected.

A flip-flop 9 is reset by the output of the first comparator 3 to output a positive signal, and is reset by the output of the second comparator 7 to eliminate the positive signal output. Reference numeral 10 denotes an AND circuit which operates with the output of the second pulse oscillator 5 and the positive output of the flip-flop 9 as inputs, and outputs a pulse motor drive signal.

12 is an additional injection switch, and 17 is an additional injection timing control device which will be explained in detail later. When the additional injection switch 12 is turned on, it outputs a second signal to the flip-flop 16 to drive a pulse motor that moves the piston of the syringe. However, a timer 23 is built in so that the second signal will not be output even if the additional injection switch 12 is turned on again before a predetermined period of time has elapsed. 13 is a third counter that counts the output pulses of the second pulse oscillator 5; 15 is a second injection dose memory that stores the additional injection dose;
Use a wheel switch, etc. 14 is a third comparator, which compares the set value of the second injection amount memory 15 and the count value of the third counter 13, and when the comparison result reaches a predetermined value, that is, the value set in the memory 15 is set. Flip-flop 1 transmits a signal to stop the pulse motor that moves the piston of the syringe when a time corresponding to a predetermined additional injection amount has elapsed.
Output to 6. With the above configuration, an additional injection is started by turning on the additional injection switch, and a predetermined additional injection amount set in the memory 15 is injected.

A flip-flop 16 is set by the output of the additional injection timing control device 17 to output a positive signal, and is reset by the output of the third comparator 14 to eliminate the positive signal output. 11 is the output of the second pulse oscillator 5 and the flip-flop 16
This is an AND circuit that inputs the output of , and outputs a pulse motor drive signal.

18 is an OR circuit which receives the outputs of AND circuits 10 and 11; 19 is a pulse motor drive circuit; 20
is a pulse motor for driving the piston of a syringe.

Next, regarding the additional injection timing control device 17, the second
This will be explained using figures. 12 is an additional injection switch, 2
1 is an AND circuit, 22 is a flip-flop, 23
is a timer that outputs a signal after a certain period of time has elapsed after the signal is input, and when the additional injection switch 12 is closed, the output from the power supply and the normally set output of the flip-flop 22 are connected to the AND circuit 2.
1 is input. The output of the AND circuit 21 is input to the third counter 13 and the flip-flop 16, and also resets the flip-flop 22 to stop the output to the AND circuit 21. Therefore, even if the additional injection switch 12 is closed again, the AND circuit 2
No signal is output from 1. On the other hand, timer 2
The signal inputted to the flip-flop 23 starts the timer 23, and when a certain period of time has elapsed, the timer 23 generates an output, returning the flip-flop 22 to the set state again and returning to the initial state.

Next, control of the injection operation by the circuit shown in FIGS. 1 and 2 will be explained.

First, the injection time interval is set in the memory 4, the injection dose is set in the memory 8, and the additional injection dose is set in the memory 15. Further, a predetermined time to operate is also set in the timer 23 in the additional injection timing control device 17.

When the power is turned on and operation starts, the first comparator 3 compares the count value of the first counter 2 that counts the output pulses of the first pulse oscillator with the injection time interval setting value stored in the memory 4. and outputs a first signal that drives a pulse motor that drives a piston of a syringe when a predetermined time interval has elapsed.

This signal sets flip-flop 9 and produces a positive output. Its positive output is applied to AND circuit 10. On the other hand, AND circuit 10
Since the pulse from the second pulse oscillator 5 is applied to , and the positive output is applied from the flip-flop 9, this pulse (pulse from the oscillator 5) is applied to the AND circuit 10, the OR circuit 18,
is applied to the pulse motor 20 through the pulse motor driver 19 to rotate the pulse motor 20,
Start injecting the drug.

On the other hand, the output of the first comparator 3 is also input to the second counter 6, and the second counter 6 activated by the input signal starts counting the output pulses of the second pulse oscillator 5. . The second comparator 7 compares the predetermined injection dose setting value stored in the memory 8 with the count value of the second counter 6, and resets the flip-flop 9 when the injection of the predetermined injection dose is completed. do. As a result, the pulse from the second pulse oscillator 5 that had passed through the AND circuit 10 no longer passes through the AND circuit 10, the rotation of the pulse motor stops, and the injection of the injection drug ends.

Next, control of the additional injection operation will be explained.
When the patient closes the additional injection switch 12, the output from this and the normally set output of the flip-flop 22 are input to the AND circuit 21, so that the output from the AND circuit 21 is input to the third counter 13. The counter 13 starts counting the output pulses of the second pulse oscillator 5. The output of the AND circuit 21 also sets the flip-flop 16. Since the output of the flip-flop 16 is input to the AND circuit 11, the pulse output from the second pulse oscillator 5 passes through the AND circuit 11, further passes through the OR circuit 18 and the pulse motor drive circuit 19, and is applied to the pulse motor 20. , the pulse motor 20 is rotated to start injecting the injection drug.

The third comparator 14 compares the additional injection dose set value set in the memory 15 and the counted value of the third counter 13, and when the two match, that is,
The flip-flop 16 is reset when the injection of the set additional injection dose is completed. As a result, the pulse from the pulse oscillator 5 that had passed through the AND circuit 11 no longer passes through the AND circuit 11, and eventually the rotation of the pulse motor 20 is stopped, and the injection of the additional injection drug is completed.

In the additional injection timing control device 17, when the patient first closes the additional injection switch 12, a positive output is generated from the AND circuit 21, the injection operation is started, and the flip-flop 22 is reset. Even if the injection switch 12 is closed, no output is obtained from the AND circuit 21, and no additional injection operation occurs. However, at the same time as the flip-flop 22 is reset, the timer 23, which counts a predetermined period of time, starts counting, and the output generated upon completion of the counting causes the flip-flop 22 to return to the set state again. That is, since the initial state is maintained after the predetermined time counted by the timer 23, the patient can perform an additional injection at any time after this time by closing the additional injection switch again.

The settings of the memories 4, 8, 15 and timer 23 used in the auto-injector described above are set in advance by the doctor according to the patient's symptoms, but the thumb wheel switch used for these settings is As mentioned above, since it is a rotating type, there is a risk that it may be rotated by the patient or accidentally rotated by contact from the outside. To prevent such a situation from occurring, a setting value fixing device that prevents the preset setting value from being changed may be provided instead of the thumb wheel switch.

[Effects of the Invention] As described above, according to the present invention, not only can a predetermined amount of injection be automatically performed at predetermined time intervals, but also when a patient requires an additional amount of injection, This is possible by operating a switch. Furthermore, in order to prevent this additional dose from being injected frequently by mistake, once the additional dose has been injected, it will not be injected again until a certain period of time has elapsed. Since a control mechanism is provided, injection can be performed automatically and safely.

[Brief explanation of the drawing]

The drawings show an embodiment of the auto-injector of the present invention; FIG. 1 is a block diagram of the electronic circuit that controls the auto-injector, FIG. 2 is a block diagram of the electronic circuit of the controller, and FIG. 3 shows the thumb wheel.・This is a schematic diagram of the external appearance of the switch. Explanation of symbols, 1...first pulse oscillator, 2...
...first counter, 3...first comparator, 4...
injection time interval memory, 5... second pulse oscillator, 6... second counter, 7... second comparator, 8... first injection dose memory, 9... flip-flop, 10... AND circuit, 12...Additional injection switch, 13...Third counter, 14
...Third comparator, 15...Additional injection dose memory, 16...Flip-flop, 17...Additional injection timing control device, 18...OR circuit, 19...Pulse motor drive circuit, 20...Pulse motor .

Claims (1)

[Scope of Claims] 1. An automatic injector that injects an injection drug by driving the piston of the syringe via a pulse motor, comprising: (1) a first pulse oscillator that generates a reference pulse; and the first pulse oscillator. a first counter for counting output pulses of the first counter; an injection time interval memory capable of setting and storing a predetermined injection time interval; a count value of the first counter and a setting value of the injection time interval memory; (2) a first comparator that outputs a first signal that drives the pulse motor when the comparison result reaches a predetermined value; (2) a first comparator that generates a reference pulse; a second pulse oscillator, and a second counter that starts counting output pulses of the second pulse oscillator in response to a first signal output from the injection time interval control device that drives the pulse motor; Comparing the counted value of the second counter and the set value of the first injection dose memory with a first injection dose memory in which a reference injection dose of the injection drug can be set and stored in advance; a first injection dose control device comprising a second comparator that outputs a signal to stop driving the pulse motor when the comparison result reaches a predetermined value; an additional injection timing control device that outputs a second signal for driving the pulse motor when a switch is turned on; (4) a second injection drug that can preset and store an injection amount of a predetermined additional injection drug; a third counter that starts counting output pulses of the second pulse oscillator in response to a second signal for driving the pulse motor output from the additional injection timing control device; 3
a third comparator that compares the counted value of the counter with the set value of the second injection dose memory and outputs a signal to stop driving the pulse motor when the comparison result reaches a predetermined value; Additional injection dose control device equipped. An automatic injector characterized by comprising: 2. In an automatic injector that injects an injection drug by driving the piston of the syringe via a pulse motor, (1) A first pulse oscillator that generates a reference pulse and the output pulses of the first pulse oscillator are counted. A comparison result is obtained by comparing a first counter, an injection time interval memory in which a predetermined injection time interval can be set and stored, and a count value of the first counter and a set value of the injection time interval memory. (2) a second pulse oscillator that generates a reference pulse; (2) a second pulse oscillator that generates a reference pulse; a second counter that starts counting output pulses of the second pulse oscillator in response to a first signal output from the injection time interval control device that drives the pulse motor; and a reference injection amount of the injection drug. The counted value of the second counter is compared with the set value of the first injection dose memory, and the comparison result is a predetermined value. (3) a second comparator that outputs a signal that causes the pulse motor to stop driving when the pulse motor reaches the pulse motor; A second signal that outputs a second signal that drives the motor, and measures the elapse of a predetermined set time in response to the signal, and that drives the pulse motor even if the additional injection switch is turned on again during timing. (4) a second injection dose memory capable of presetting and storing the injection amount of a predetermined additional injection; a third counter that starts counting output pulses of the second pulse oscillator in response to a second signal output from a timing control device that drives the pulse motor;
a third comparator that compares the count value of the counter with the set value of the second injection dose memory and outputs a signal to stop driving the pulse motor when the comparison result reaches a predetermined value; Additional injection dose control device equipped. An automatic injector characterized by comprising: