JPS622962A - Applicator for warming medical treatment - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed description of the invention]

[Industrial Application Field] The present invention relates to an applicator for heating therapy, and more particularly to an applicator for warming therapy for treating a predetermined location of a living body using electromagnetic waves. [Conventional technology] In recent years, heating therapy

[Therapeutic methods using [also called hyperthermia 1] have been attracting attention, especially for l'lJ tumors, for example, by continuously heating them at around 43°C for 1 to 2 hours, and at the same time treating them with a certain amount of heat. Research reports have been made one after another that by repeating this, it is possible to inhibit the regeneration function of cancer cells and at the same time kill many of them. 1
0). This type of heating therapy 7 includes a general heating method and a local heating method. Of these, 11 local heating methods that selectively heat only the weave and its surroundings include a method using electromagnetic waves;
A method using an electric wire, a method using ultrasonic waves, etc. have been proposed. On the other hand, the inventors have previously proposed and are conducting research on effective P1 in the case of heating treatment of cancer not only on the body surface but also deep within the body using electromagnetic waves. In this case, especially the addition 11' for sending electromagnetic waves into the living body! The inventors have conventionally adopted a method of equipping an applicator with a radio wave lens due to the need to focus the energy of electromagnetic waves. Specifically, as shown in FIG.
A case main body 3 having a function as a waveguide, an electromagnetic wave power supply part 2 installed in one end of the case main body 3,
The main part is a radio wave lens section 4 provided in the other end, and a cooling plate 5 is provided at the output stage of the radio wave lens section 4 to prevent the surface from being exposed to the LV body. At the same time, the cooling plate 5 can be cooled by the cooling water W. [Problems to be Solved by the Invention] However, in such a conventional example, the energy loss of electromagnetic waves inside the applicator 1 is relatively large. For this reason, the inventors have already proposed filling the applicator with oil that reduces the attenuation of electromagnetic waves (Special Edition No. 59-8692). On the other hand, also in this A-ile filling application 4', the radio wave lens part and the coins 1;
Due to the impedance mismatch with the FJ river crystal i'ji side, the magnetic wave fouling (1 shift, dirt) causes a standing wave to be generated in the electromagnetic wave transmission system in the other room of the electromagnetic wave power supply section. ,
This causes the inconvenience that the electromagnetic wave transmission system is overheated and a significant amount of energy 10 is generated. In order to improve this inconvenience, a second trial has been carried out in which an alignment member is installed between the radio wave lens and the electromagnetic power feeding section as described in tiii. However, even in this case, such matching part (A
Since it is fixed, it can sufficiently cope with impedance changes at multiple locations and impedance changes due to shape changes that occur when using the J5 radio wave receiver. However, the disadvantage is that it is not possible to achieve sufficient impedance matching. [Illustrative aspects of the invention] The present invention has the following features: (1) Improved disadvantages of the conventional example; We propose an applicator for heating therapy that can efficiently focus electromagnetic energy at a predetermined location within the body and heat it by sufficiently matching the impedance between the body and the body. [Means for Solving the Problems] Therefore, the present invention provides a case body having an electromagnetic wave feeding section at one end and a radio wave lens section and an electromagnetic radiation end section at the other end, In the heating therapy applicator having a cooling mechanism for cooling the surface side of the heating unit installed on the electromagnetic wave emitting end side, the case body portion between the electromagnetic wave power supply unit and the radio wave lens unit is waterproof. The structure is equipped with a stub matching means, and the case body is filled with a fluid such as insulating oil that has little attenuation of electromagnetic waves in the part where the stub matching means is installed and on the side of the electromagnetic wave power supply part. The structure is such that a fluid storage means is attached to a part of the side wall, thereby attempting to achieve the above-mentioned purpose. For electromagnetic waves that propagate and appear from the wave radiation end to the outside, first, from the radio wave lens part,
゛ζFrom the surface of the cow's body, each impedance is
A reflected wave r based on the Q'je combination is generated. In this case, according to the present invention, the adjustable stub matching means (I): 1) generates a reflected wave r' with respect to the H-wave feeder; ...-r
(equal amplitude and opposite phase). , -, the fouls r and r'! 71 cancel each other out from the electromagnetic wave feeding section, there is no reflection, and impedance matching to the load side is completely established. Therefore, there are almost no reflected waves, and the energy that is generated due to the interference can be greatly suppressed. In addition, when the stub alignment means is adjusted, the pressure of the filled oil will increase or decrease due to the change in volume, but in this case, the first stage of fluid accommodation will immediately act L7 to absorb this. , which allows for smoother adjustment of the stub alignment means. [First Embodiment of the Invention] The first embodiment of the present invention is shown in FIGS. 1 to 11 below! , (This will be explained further. First, in Fig. 1, a case main body having a function as a 1.0 !;i waveguide is shown. This case main body] 0 is also clear in Figs. 2 and 3. The electromagnetic wave feeding part 11 is provided at one end, the radio wave lens part 12 is provided at the other end, and a stub matching function for electromagnetic wave matching is provided in the middle part. A stabilization mechanism 13 is equipped.Furthermore, the right end of the mI recording radio wave receiver 12 as shown in FIG. Part 14
is equipped with a cooling mechanism 15 for cooling the surface of the living body so that the electromagnetic wave emitting end 14 is so-called from the outside. The electromagnetic wave feeding section 11 includes a feeding section m-wave tube 10Δ forming a part of the case body 10, an excitation antenna 1.1A protruding from the center of the feeding section m-wave tube 10A, and this excitation antenna. It is formed by a waterproof coaxial connector IIB for electromagnetic waves connected to IIA. As a result, the electromagnetic waves 6 sent through the coaxial connector 11*3 are efficiently introduced into the case body 10 4'1.
It has become so. Inside the power feeding part m-wave tube 10A, the insulation oil (hereinafter referred to as 1 oil-1) 10C with small attenuation of electromagnetic waves is installed in the stazochi 1 and the inner mechanism 13 (including the +!A location).
is filled. 100 +:', said oil IOC
This shows an oil 11-person partition plate consisting of a dielectric part +4 for enclosing oil. In this embodiment, rtii 詑 stub chiko, chi 1 black tfJ 13 are 3 arranged on the same plane at a predetermined interval.
A number of wood-H1 stubchi 1 Lee-1 pieces are used. To explain this in more detail, each of these stub tuners 1
5A. Each of 1313.13c is -'-! 'ilf is open'
The inside of the cylinder part 2I and this cylinder part 21 is
A waterproof screw part 22 that moves back and forth and a stub alignment function integrated with this piston member 22 are provided.
ii. a screw member 23, a screw hole 24 for tightening the screw portion 4-23 by 1 mp-thread, and the case body 10.
It is constituted by a through hole 25 of 21LL or 21LL that communicates between the inside and the inside of the cylinder part 21, and by rotating each screw member 23, the screw member 23 can be appropriately protruded into the case body 10 and can be installed as required. Consistency is now being achieved. In this case, the communication through hole 25 is the screw I/N member 2.
2 shows a flow port for the movement of the oil 10C that occurs with the reciprocating movement of the oil 10C. In addition, such oil 1. In order to smooth the OCO flow, that is, the reciprocating movement of the piston member 22, and to allow thermal expansion of the filled oil due to overheating of the case body caused by continuous use, a part of the power supply m-wave tube 10A is A fluid storage means 16 is provided. In this embodiment, the fluid storage means 16 includes through holes 16A and 16 formed at three locations at predetermined intervals to the power feeding section m-wave tube 10.
A, a wire mesh 16B with a fine comparison curve arranged and equipped so as to cover each through hole 16A from the inside, guide tubes 16C, 16C connected to each through hole 16A, and each guide tube 16C. A relatively soft oil vent connected to and extending to one side of -1
1). Here, the wire mesh 16B
constitutes a part of the side wall of the electromagnetic wave feeding section +'+l (i 1). Therefore, if it functions in the same way as -ne, for example, a plurality of small holes can be directly provided in the inner wall of the electromagnetic wave feeding section. It may also be replaced with a plate-shaped metal i?lXI4 having countless V1 through holes.Furthermore, the cooling mechanism 15 installed at the electromagnetic wave JJ radiating end 14 of the case body 10 is The cooling mechanism 15 is formed into a flat shape in order to efficiently cool the surface of the AFL section. 1 (with board 30,
A keto-shaped coolant inlet 3OA formed at one end of the anchoring substrate 30 and a correspondingly rectangular coolant outlet 30B formed at the other end of the anchoring substrate 30.
and a waterproof insulating film barrier [1" groove 30C installed in a 3L manner surrounding the opening D10E of each of these coolant inflow/outflow RJ30A, 30B and the electromagnetic wave radiation end X4, and coolant inflow I] 30△ and coolant outflow [131, 131, 32 connected and fixed to OB, and a flat shape arranged so as to cover substantially the entire surface of the electromagnetic wave radiation section 14. It is formed of an insulating film member 33 and a frame plate 34 that is detachably attached to the anchoring board 30 with the insulating film member 33 waterproofed around the insulating film member 33.
The insulating film member 33 has a convex shape on the outside and an opening on the inside, and is formed of a film-like dielectric material with low attenuation of electromagnetic waves. And coolant inflow n3
The cooling water flowing in from 0A is the 8f! ! The coolant flows inside the membrane member 33 and flows out as indicated by the arrow f in FIG. 1 030E.
(-1 is sent out, but during this time the insulation j model part 4
33, the surface of the living body can be efficiently cooled. In this embodiment, the radio lens section 12 installed at the right end of the case body 10 in FIG. 1 is shown in FIGS.
As shown in the figure, it is formed into a box shape with two opposing sides open, and the entire box is removably housed within the gauge main body 10. Let me explain this in more detail.
consists of the same −−=−J method and several pieces of gold 1. ;↑;temporary 40. ．． 2') is formed by the frame body 41 which locks the lower part of each metal 1j40 as shown in FIG. 6. Among these, each of the metal plates 40 has a dimensional width α at the center thereof, as shown in the IAI. As well as counting the maximum number of people, 1 (1f mark frame 41 (!!II wall,
α, is set to decrease as it approaches . α26 α, dimensional width (I[1shi2, α0〉α1〉α
2〉α3), and the incoming electromagnetic wave C due to dirt
As shown by the dotted line in FIG. 10, each metal plate 40 arranged in two rows can exert a predetermined lens effect in one direction.)
is set to . The metal plates 40 each have a shape in which the center of the end of the electromagnetic wave feeding section 11 is cut into an arcuate shape. Then, as shown in Fig. 9, a predetermined 1 men's effect is generated in the other direction as well (1i+iL).
It is set to C. FIG. 11+2 shows a right side view of FIG. 1 when the radio wave lens section 12 formed in this way is housed in the case body 1 (however, the insulating film member 33 is removed). In this case, both the electromagnetic wave incident side and the electromagnetic wave emission side of the radio wave lens section 12 are open, so that the cooling liquid in the cooling mechanism 15 described above can very easily flow into the radio wave lens section.・It has a structure that can leak out.In addition, in FIG.
+I- female thread for - is not shown. -The box-shaped radio wave lens part 2, which is detachably formed as described above, is actually 1
At the same time, 31. Ten pieces are prepared in advance depending on the affected area, and can be selected and used as appropriate. Further, on the side of the electromagnetic wave power supply unit 11 of the radio wave lens unit 12 described in 1tii, a piping 39 with a relatively small diameter is installed as a bubble escape means and is connected to the coolant guide 32 of the coolant Nagatagawa. The air bubbles are sucked out directly from the coolant guide 32 to the first part by the negative pressure accompanying the flow of the coolant. At U7, the abrinone router 50 for heating therapy, which is formed as shown in FIG. At the IOH part, as shown in FIG. 5] iJ diagram L2
It is supported by a support mechanism that does not have any structure, and is configured to be rotatable as shown in the arrows F, F, F, and C1 so that it can adapt to the required weight and take any desired posture. . Next, the overall operation of the above embodiment will be explained in detail. First, a 2°C input signal is input from the antenna IIA through the coaxial connector 1tB and directed into the base body 10. The output electromagnetic waves are sent as they are without being attenuated in the oil 10C.Then, in the process of propagating through the radio wave lens section 12, the electromagnetic waves are transmitted to the radio wave lens section 12. Therefore, the 1-Men's effect is applied to the electromagnetic wave at the time it is radiated from the radio wave lens section 12, and the radiation and focusing are done simultaneously.What is the effect of this lens effect? After propagating inside the mechanism 15, it is propagated from the surface to the living body side, but during this time, it is first partially reflected on the living body surface, and then the living body surface and deep part are heated.In this case, the living body surface is heated by the above-mentioned cooling. It is effectively cooled by the mechanism 15. In addition, since the deep part is focused by the omnidirectional lens effect of the radio wave lens, the focal position at a predetermined depth and its surroundings are efficiently heated. The reflected wave on the surface of the living body is due to the difference in impedance of the electromagnetic wave transmission system, and this impedance change also occurs on the incident side of the radio wave lens section 12. Therefore, when viewed from the excitation antenna 11A side, the above-mentioned radio wave It is possible to detect an electromagnetic wave of 1 = 1 from both the surface of the lens section 12 and the heating section.In this case, by appropriately adjusting the stub tuner mechanism 13, it is possible to detect the electromagnetic waves from both the surface of the lens section 12 and the heating section. Impedance matching can be achieved with respect to the side, and as this suppresses the generation of reflected electromagnetic waves, electromagnetic energy is efficiently sent into the heating section.In other words, from the electromagnetic wave feeding section 12 to the inside of the case body 10 as a waveguide. Propagating the electric current (wave number 11 from the end 14 to the outside)
, first radio waves

[/nf, from part 12 + 'lrA and 4 from the body surface. A reflected wave r is generated based on each impedance mismatch. In this case, according to the present invention, a reflected wave r' is formed on the electromagnetic section 12 by the adjustable stub matching means B, and the three stub tuner mechanisms 13 are adjusted. and set r/=-r (equal amplitude and opposite phase). If you do it like this, reflection 1 and r
′ cancel each other out, which means that the electromagnetic wave feeding section 12
When intertwined, there is no reflection, and impedance matching to the load side is completely established. Therefore, the number of reflected waves is completely eliminated, and the accompanying energy flow is also greatly suppressed. Here, specifically, the impedance matching by the stub tuner a+M 13 is performed by the coaxial':I vector 11B.
This is done by the operator while observing the reflection rate displayed on the counter electromagnetic wave table (not shown) of the directional coupler used in connection with the directional coupler. Apart from the impedance matching by the stub chainer mechanism 13, a little less than 1 energy is generated in the case body 10 due to the impedance of the electromagnetic wave transmission system, and this is caused by the continuous use of the applicator. Constant heating of the oil 10C causes thermal expansion of the filled oil 100, which poses a problem in countermeasures. In this case, if left as it is, for example, the oil-filled partition plate 1.0D will be damaged, but the above-mentioned fluid storage means 16 acts against this and absorbs the increased amount of filled oil 10C due to thermal expansion. It is designed so that it can be easily sent outside. On the other hand, this fluid storage means 16 also has the function of being able to be used as is even when replacing the 6-year-old filling oil IOC. In addition, since the radio wave lens unit 12 has a structure that can be replaced very easily, if the radio wave lens unit 12 with different convergence degrees is selectively used depending on the deep position, the efficiency can be increased by l,
Warming therapy can be performed. For this reason, in this embodiment, when performing heating therapy on the deep part of the living body that has become calm, ・Switching including adjustment of impedance matching is necessary. Impedance matching during heating treatment can be achieved more quickly, and the heating time can be set sufficiently, while many applicators ! There is an advantage that the entire device can be obtained at a relatively low cost since there is no need to prepare one piece of equipment. [Second Embodiment] Next, a second embodiment of the present invention will be described based on FIGS. 12 to 14. This embodiment is based on the stub matching means 1 of the first embodiment described above.
3 (See Figure 1)
This is different from the first actual Mij example described above in that C is of a completely sealed type. That is, in FIGS. 12 to 14, 10B,
As in the case of the first embodiment described above, a case main body having a function as an m-wave tube is shown. This case body 10 includes
An electromagnetic wave power feeding section] 8 11 is provided at one end, a radio wave lens section 12 is provided at the other end, and a stub or nut mechanism 63 as a stub matching means for electromagnetic wave matching is provided at the intermediate section. There is. The stub tuner mechanism 63 is a Miki stub bar 66.
Each stub bar 66 is connected to the case body 10.
A suitable amount thereof is formed so as to be able to protrude separately from the inside. To explain this in more detail, each of Miki's stub tuner mechanisms in the stub tuner mechanism 63 has an open end L1.
The cylinder part 64 that has been inserted into the cylinder part 64, and the piston part that reciprocates inside the cylinder part 64 (a predetermined through hole fixed to the - part of the AC3 and formed in the case body 10), and the OS is loosely inserted into the case body. It is composed of a stub bar 66 that is installed so as to project inward, and a locking mechanism 67 that is rotatably installed in the opening of the cylinder section 64 and forces the screw I/N member to reciprocate. Among these, the screw mechanism 67 fixes the driving screw portion 67A and is only allowed to rotate, and is attached to the cylinder portion 64.
(snap pin fi 7 that locks one-way removal to the outside)
C and a seal portion 4.4'67 attached to the drive portion 4A'67B. and,
As shown in FIG. 14, when the drive unit +A6713 is rotated through the two small drive holes 67E and 67E formed in the drive member 67B, the drive screw integrated with it The part 67Δ rotates without changing its position, so that the piston part (AC3) moves back and forth within the cylinder part 64 due to its rotational reaction force, thereby causing the stub bar 66 integrated with the piston member 65 to rotate. The amount of protrusion into the case body 10 is adjusted appropriately. Reference numerals 64A and 658 each indicate one oil flow hole. A fluid accommodating means 76 is provided at the left end.
A fluid 1 storage section 10E having a certain spatial area provided at the left end of M, a fine wire mesh 76A that partitions between this fluid storage section 10E and the power feeding section waveguide 10A section, and the A cup-shaped soft member 76B having a concave cross section and a convex portion at the center thereof is inserted into the fluid storage portion 10E from the outside, and the electromagnetic wave power feeding portion 11 is inserted into the center portion of the cup-shaped soft member 76B from the outside. A coil spring 76C that constantly presses gently toward the side, and this coil spring 76
and a lid member 76D that locks the cup-shaped soft member 76B and sealingly attaches the cup-shaped soft member 76B to the case body 10. 76E indicates a screw that locks the coil spring 76C, and 76F indicates a vent hole formed in the lid member 76D. Here, the wire mesh 76A constitutes a part of the side wall of the electromagnetic wave power supply section 11, and therefore, if it functions equivalently, for example, a plurality of small holes may be directly formed in the inner wall of the electromagnetic wave power supply section 11. However, it may be replaced with a plate-shaped metal member having numerous small through holes. Therefore, not only in the case of impedance matching by the stub tuner mechanism 63, but also in the case where the filled oil IOC expands in volume due to heat, the fluid accommodation means 76 immediately acts to accommodate the increased amount of the filled oil IOC. I'm starting to get it. Specifically, the central portion of the cup-shaped soft member 76B is compressed by the oil pressure, and the increased amount of filled oil is accommodated in the expanded fluid storage section OIE. As shown in FIGS. 12 to 14, the other configurations are completely the same as those of the first embodiment described above. Even in this case, in addition to having the same effect as the first embodiment performed 3AC previously, the amount of filled oil IOc pushed out into the case body 10 is only a small amount hl, especially when adjusting the stabilization mechanism 63. It is possible to downsize the storage means 7G, and there is an advantage that it is possible to obtain an applicator that is completely sealed and can be filled with oil once a month and is easy to handle as a whole. In addition, although each of the above-mentioned embodiments illustrated the case of a stub tuner mechanism based on three stub tuners, the present invention is not limited to 4 or 7; for example, one waterproof type stub tuner a There is also a case-C that applies exactly as it is to those using the structure. [Effects of the Invention] Since the present invention functions in the following configurations as shown in I-B and B, according to this, even if reflected electromagnetic waves propagate from a plurality of places toward the electromagnetic wave power supply side, these can be transferred to the stub matching means. This makes it possible to achieve impedance matching very easily, and since the fluid storage means can be removed, impedance matching can be achieved very easily even during heating treatment. We have developed an unprecedented, superior applicator for heating therapy that can more efficiently focus and deliver electromagnetic energy, and therefore perform deep tissue therapy relatively efficiently even under adverse conditions with severe temperature changes. I can do it.

[Brief explanation of the drawing]

FIG. 1 is a sectional view including a coolant guide portion showing an embodiment of the present invention, FIG. 2 is a right side view of FIG. 1, FIG. 3 is a plan view of FIG. 1, and FIGS. The figures are a perspective view showing the radio wave lens part used in Fig. 1, Fig. 6 is a front view taken from the arrow ■ in Fig. 4, and Fig. 7 is a perspective view showing the radio wave lens section used in Fig. 6. 8 is a sectional view taken along the line ■-■ in FIG. 7, FIGS. 9 and 10 are explanatory diagrams showing the action of the radio wave 1/ns section, and FIG. 11 is a sectional view taken along the line ■-■ in FIG. 7. FIG. 12 is a perspective view showing the installed state of the applicator in use, and FIG. 13 is a left side view of FIG. 12, FIG. 14 is a plan view of FIG. 12,
FIG. 15 is a perspective view showing a conventional example. 10... Game body, ], OC...
Insulating oil, 11... Electromagnetic wave power supply section, 12...
...Radio wave lens part, 13゜63...Stub tip as stub alignment means, ner mechanism, 14...
Electromagnetic wave radiation end, 16.76...Fluid storage means. Patent applicant Makoto Kikuchi (3 others) is deaf
ヰj、j L-、、、、J Fig. 6 Fig. 7 ■ Fig. 8 I2 Fig. 9 Fig. 1O Fig. 25

Claims (1)

[Claims] (1) A case body having an electromagnetic wave power feeding part at one end and a radio wave lens part and an electromagnetic radiation end part at the other end, and a heating part equipped on the electromagnetic wave radiation end side of the case body. In the heating therapy applicator having a cooling mechanism for cooling the surface side, a waterproof structure stub matching means is provided in the case main body portion between the electromagnetic wave power feeding part and the radio wave lens part, and the stub matching means has a waterproof structure. The case body at the equipment location and the electromagnetic wave power supply portion is filled with a fluid such as insulating oil that reduces electromagnetic wave attenuation, and a fluid storage means is provided on a part of the side wall of the case body. Applicator for heating therapy.