JPS6219298A - Composition for water treatment - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to improved dispersible tablets and granulated products. More particularly, water treatment such as cooling tower water for air conditioning purposes, where a relatively water-soluble matrix material acts as a dispersant for less water-soluble water treatment chemicals. Regarding tablets.

It is known in the tablet art to use less soluble substances with more easily soluble ingredients to increase the solubility of relatively less soluble substances. For example, when prescribing an aspirin component, a combination of aspirin (a substance with low solubility), sodium bicarbonate and citric acid (substances with relatively high solubility) may be used.
It is well known that It is also known to mix poorly water-dispersible antibiotics with highly water-soluble polymeric substances to increase the water solubility of the antibiotic.

This is shown in US Pat. No. 3,089,818.

However, these prior art examples do not involve the production of a gaseous product (Co2) to aid in the dissolution of aspirin products or mutually in non-aqueous solvents, such as the example of antibiotics and polymeric substances. depends on.

The use of water treatment agents such as aminophosphonic acids in combination with triazoles and metal molybdates to prevent scale precipitation is well known.

An example of this combination and its use together with polyacrylic acid or its salts as a dispersant for treating impurities in water is given in U.S. Pat. No. 4,138.353:4.2.
No. 17.216: No. 4.246.030 and No. 4,
No. 277.359. U.S. Pat. . Furthermore, the use of aminophosphonates for water treatment without polyacrylic acid is also known. This is shown, for example, in U.S. Pat. No. 3,666.664 as well as U.S. Pat. No. 4,101,441, which includes azoles, and these compositions contain briquettes (
It is stated that the briquette can be added to the water by a conventional bypass feeder.

It is an advantage of the present invention to provide a water treatment composition in the form of tablets or granules in which a relatively water-soluble material acts as a matrix for a less soluble dry water treatment material. It is. Other advantages of the invention are:
- In an embodiment, a polymeric material is provided as a more water-soluble matrix material for a relatively less water-soluble water treatment agent. Yet another advantage of the invention is that it provides a dispersion matrix of the type described above in which one of the water treatment agents acts as a dispersant for less water soluble water treatment agents. be.

Yet another advantage of the present invention is that the matrix provides a water-soluble matrix for water treatment materials that rapidly disperses the water treatment agent. Another advantage is that the granulated products and tablets are easily adaptable to manufacture and use with current tablet compounding methods and technology.

The foregoing advantages of the present invention are that water-soluble matrix materials in granular and discrete particulate form are intimately mixed and combined with water-soluble water treatment agents that are less water-soluble than said matrix materials that are relatively more water-soluble. This is achieved by the water treatment composition of the present invention in the form of tablets or granules.

- In embodiments, the polymeric material is a water-soluble matrix material as described above. It is used in granular form and is first treated with alcohol to blanket the granular resin before mixing with the dry water treatment chemicals.
do. A water treatment agent is mixed with a gas-sealed polymeric material, and the mixed material is mixed with water. This treatment with water binds the polymer molecules together and traps the active compound within the polymer 71-lix. Granulation leaves a relatively small amount of air in the tabletting process.

This method is called “Tablet Granulation” (T
is the subject matter of application no.

In other embodiments, organic compounds, such as those represented by one or more water-soluble water treatment agents, are used as a matrix to treat less water-soluble water without the use of alcohol or water. mixed with the drug used. Tablets can be made by granulation of these materials, which quickly disperse in water.

In yet another embodiment, the polymeric material can be used as the water-soluble matrix without alcohol treatment as described above. This can be formed into granules with water treatment agents and subsequently tabletted.

A particularly suitable water-soluble polymeric material is polyacrylate, and preferably its sodium salt. This type of resin is called Goodrite.
759 or Cryanmer P
It is commercially available as 35. Water-soluble polymeric substances are
It must expand on contact with water. This means that the polymeric material has a high affinity for water. The method of the invention solves the problem of combining low water-soluble active substances with this type of resin, and
Acrylic polymers, including polyacrylate polymers and copolymers such as polymethacrylate, polyacrylamide, polyacrylic-coacrylamide and polymethyl-acrylamide; polyvinyl acetate-1-,
Vinyl resins, including polyvinyl alcohol and polyvinyl methyl ether, and any polymeric materials with these properties, such as oxides of polyethylene and polypropylene and polyoxymethylene, would also be useful.

The polymeric material can be used in its basic form or as a cationic or anionic salt.

One type of water treatment agent that may be combined with water soluble polymeric materials is hexamethylene diamine-tetramethylene phosphonic acid compounds, commonly known as phosphonates in the water treatment art. This substance is Dequest
It is commercially available as 2051. This component is used to break up crystal formation and therefore this component prevents scale formation of calcium carbonate and magnesium hydroxide.

This material is also effective as a mild corrosion inhibitor.

Other corrosion inhibitors are benzotriazoles or polytriazoles. This is the trade name Cobra Tech (Cobr)
It is sold as atec).

Used as a corrosion inhibitor in combination with sodium molybdate and Cobratec materials. However, this material is not water soluble, as are the polymeric materials or materials described above as corrosion inhibitors. Other molybdate compounds that can be advantageously used as granules and tablets according to the invention are phosphates. Salts of rare earth elements with limited solubility in water can also be used if desired.

Other chemical compositions that can be used with the water-soluble matrix are water treatment biocides such as quaternary ammonium compounds or trisodium phosphate, which can be used in combination with the matrix as an aqueous solution for boiler scale treatment.

Granulation aids can also be used. These would also include antifoam agents such as condensates of ethylene oxide. This material has a hydrophobic base and is a surfactant, reducing foaming by changing the surface tension of the cooling water.

flow enhancers such as fumed silica, commercially available as CabaCil;
enhancer) can also be used to aid the dry blending process prior to tabletting. Additionally, Betsugu (P
Polyethylene glycol, commercially available as eg) 8000, can also be used. This material melts under 140°C or liquefies under shear. This material is used as a die lubricant in the tabletting process. This material has additional properties as a binder with other powders during tabletting.

A preferred alcohol for gas-sealing water-soluble polymeric materials from moisture is isopropyl alcohol.

Other low carbon chain alcohols having 1 to 5 carbon atoms can also be used advantageously, which also serve to displace air from the polymer chain.

Water serves as a binder when adding water treatment chemicals to the polymeric material. The water also binds the polymer molecules together, trapping the additive material within the polymeric matrix and forming granules.

The following examples are presented to illustrate the granulate and tablet products of the present invention. These examples are not intended to limit the invention in any way.

The following Example 1 illustrates the use of a polymeric material as a tablet matrix.

Example ■ Ingredients
Weight% sodium polyacrylate 27.
675 xamethylene diamine - tetramethylene phosphonic acid 40.500 benzotriazole 6.300 sodium molybdate 13.500 ethylene oxide condensation product 0.900 fumed silica 0.225 polyethylene glycol 0.900 isopropyl alcohol 3000 water
7.000100,
000 i Sodium polyacrylate polymer is in dry powder form. This is placed in a rolding type mixer such as a Hobart mixer. While mixing, gradually add isopropyl alcohol until the alcohol and polymer are mixed. This method can be performed in 1-2 minutes. The mixture has the appearance of wet sand. In a similar manner, phosphonic acid, benzotriazole and molybdate are added individually.

After the addition of the sodium molybdate, the ethylene oxide condensation product, Fume 1 silica and polyethylene glycol are added with mixing. Subsequently water is added which acts as an adhesive and forms a polymer matrix for the phosphonic acid, benzotriazole and sodium molybdate. Due to the shearing action of the mixer on the polyacrylate polymer and the addition of water, the water binds the polymer molecules together to form a polymer matrix.

The total weight of all ingredients was 10 lbs. This granulated product was formed into 10,000 tablets using a standard punch and die tabletting machine.

The following Example 2 describes phosphonic acid and benzotriazole compounds as the matrix for the sodium molybdate solution.

Example ■ Ingredients
% by weight Hexamethylene diamine - Tetramethylene phosphone 1 95.0 Benzotriazole 2.5 Sodium molybdate 2.5 100°O All of the above components constitute a batch of the same size as shown in Tablef 1 to Formulation of Example 2. be able to. Unlike what was shown in the example, all these ingredients were placed in a Hobart mixer at the same time and mixed dry until they were thoroughly mixed. Example ■ The composition obtained after mixing
It can be made into a tablet as shown in .

The following example (2) describes sthorium polyacrylate as a matrix for benzotriazole and sodium molybdate without the alcohol treatment described in example (2).

Example ■ Ingredients
Weight% sodium polyacrylate 95.0
Benzotriazole 2.5 Sodium Molybdate 2.5 ioo.

All of the above ingredients can be processed to form the desired granules and tablets 1- by the same method as shown in Example 1.

The reason for the improved disintegration properties of the tablet formulations of the present invention having a matrix of relatively water-soluble materials is as follows. One reason for this is that the matrix material acts as a dispersant for less soluble water treatment chemicals, resulting in the matrix material dissolving away from the tablet or granule into the aqueous medium. By exposing the water treatment material in a manner that retards or controls supersaturation of relatively less water soluble materials in a given solution state. Neither the tablets nor the granules of the present invention rely on gas formation by dissolution. Bubble formation results in electrostatic binding of relatively less soluble substances, which is displaced in one direction and upwardly into stratification. On the other hand, as a highly soluble substance dissolves from a tablet or granule, a turbulent flow is generated in random directions from the tablet or granule surface and from the back side of the less soluble substance, causing the dissolution. It propels a material with low properties in a random direction from a tablet or granule, and acts similar to mechanical stirring.

It should be appreciated that relatively water-soluble matrix materials, such as polymeric materials, are in dense form and have a low surface:volume ratio, thereby providing controlled exposure to the dissolving action of water.

An additional factor in improved disintegration is the use of tablet form for the polymeric material. As portions of the polymer elute into the solution, they do not tend to surround smaller portions of the polymer due to the dimensions of the polymer in the tablet. This is a common phenomenon in plastics processing when polymers are brought into solution and is known as the formation of "fish eyes". This phenomenon is overcome by the use of tablet form.

Claims (10)

[Claims] (1) A water treatment composition in the form of a tablet or granule comprising a water-soluble matrix material present in the form of discrete particles and a water-soluble dry active water treatment agent intimately mixed with the matrix material; and because said matrix material is more water soluble than said water treatment agent,
The matrix material dissolves away from the tablet or granulate into the aqueous medium, thereby controlling the supersaturation of the water treatment agent and controlling the exposure of the matrix material. The water treatment composition described above is a composition that exposes a chemical for use in water treatment. (2) The water treatment composition according to claim 1, wherein the matrix material is a polymer material. (3) The water treatment composition according to claim 2, wherein the polymer substance is an acrylic polymer. (4) The water treatment composition according to claim 1, wherein the matrix material contains a water-soluble organic compound. (5) The water treatment composition according to claim 1, wherein the water treatment agent contains a molybdate compound. (6) The water treatment composition according to claim 4, wherein the water treatment agent is a phosphonic acid compound. (7) The water treatment composition according to claim 6, wherein the water treatment agent is a benzotriazole compound. (8) The water treatment composition according to claim 1, which is in the form of a tablet granule. (9) The water treatment composition according to claim 1, which is in the form of a tablet. (10) A water treatment composition in the form of a tablet or granule comprising a water-soluble matrix material present in the form of discrete particles and a water-soluble dry active water treatment agent intimately mixed with the matrix material; Since the matrix material is more water soluble than the water treatment agent, when the tablet or granule is placed in an aqueous medium, the matrix material is more water soluble than the water treatment agent. The substance generates vortices in random directions from the surface of the tablet or granule and from the back side of the substance having a lower solubility than the matrix material, and the substance has a lower solubility than the matrix material. The water treatment composition described above is characterized in that it is a composition that dissolves in such a way that it is propelled in random directions away from the body.