JPS62106756A - Nuclear magnetic resonance apparatus - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a nuclear magnetic resonance apparatus (NMR apparatus), and more particularly, to an NMR apparatus that can perform NMR measurements near the surface of a living body or the like with a simple configuration.

[Prior art] In the NMR diagnostic device currently under development, the whole body or a part of the body is placed in a strong magnetic field formed within a normal or superconducting magnet, and a transmitter/receiver coil is placed on the surface of the body. Attach the coil and measure the distribution or chemical shift of hydrogen or other elements in the area covered by the coil.

[Problem to be Solved by the Invention 1] As a result, the magnet becomes very large, which inevitably increases the price, and the whole body or part of the body is confined in a small space, which adds psychological burden to the patient. It is inevitable that there will be restrictions on the areas that can be measured.

The present invention is based on a new concept of measuring the object by pressing it against the end of the magnet, rather than placing the object in the magnet. NM that allows near-surface NMR measurements
The purpose is to provide an R device.

[Means for Solving the Problems] In order to achieve this object, the NMR apparatus according to the present invention has an end that can be brought close to the measurement target, and a specific part of the measurement target that the end faces. a magnet for applying a vii field in the direction vii, and a magnet arranged symmetrically with /υ between the ends in order to apply a high frequency E4j field in a direction substantially perpendicular to the magnetic field applied to the specific part to the specific part. The device is characterized by comprising a pair of transmitter/receiver coils, a transmitter circuit for supplying observation pulses to the transmitter/receiver coils, and a receiver circuit to which resonance signals induced in the transmitter/receiver coils are supplied.

[Effect 1] When the object to be measured is brought close to the end of the magnet, a unidirectional magnetic field is applied to a specific part of the object to be measured. Then, if an observation pulse is supplied from the transmitting circuit to the transmitting/receiving coil placed on the target with the end in between, the specific region receives a ta field from the magnet in one direction, and a ta field from the transmitting/receiving coil in a direction substantially orthogonal to the magnetic field. A high frequency magnetic field having a certain area is applied, and NMR measurements can be performed on this specific area.

Hereinafter, one embodiment of the present invention will be explained in detail using the drawings.

``Embodiment'' The attached drawings are schematic diagrams that do not show the structure of an embodiment of the present invention. In the figure, 1 is the object to be measured, 2 is a permanent magnet with a pole 3 that can be close to the object to be measured, and 4 is a pair of transmitter/receiver coils arranged in an inverted V shape with the pole 3 in between. , 5 is a case for supporting the magnet 2 and the transmitting/receiving coil 4, 6 is a transmitting circuit for supplying high frequency pulses for observation to the transmitting/receiving coil, and 7 is a receiving unit to which the resonance signal induced in the transmitting/receiving coil is supplied. The circuit 8 is a combicoater for processing the resonance signal outputted via the receiving circuit 7.

In the above configuration, a static magnetic field 1-1o as shown by the broken line is generated from the pole 3 of the magnet 2, and this static magnetic field )-1° is the pole 3 of the magnet 2.
is applied to a specific part of the object to be measured in the vicinity of . and,
When a high-frequency pulse (pulse train) for observation is sent from the transmitter circuit 6 to the transmitter-receiver coil 4, a high-frequency pulse magnetic field as shown by the dashed line in the figure is generated from the transmitter-receiver coil 4.

Since the resonance condition is established in the shaded region A where this high-frequency pulsed magnetic field and the static magnetic field Ho are approximately perpendicular to each other,
The observation nucleus existing in this region vJ,A is excited, and after irradiation with a high-frequency pulsed magnetic field, the resonance signal induced in the transmitting/receiving coil 4 is extracted via the receiving circuit 7 and subjected to Fourier transformation processing by the computer 8. An NMR spectrum can be obtained for . Based on this spectrum, information such as M or chemical shift of the elements present in the region A can be obtained. It goes without saying that the measurement area can be arbitrarily selected by changing the position of the magnet.

Although permanent magnets were used as magnets in the above embodiments, it goes without saying that normal conducting or superconducting magnets may also be used.

[Effects] As described in detail above, according to the present invention, the object to be measured is not placed inside a magnet, but is brought into contact with the end of the magnet, and the object is placed approximately symmetrically across this end. Since the N-j R1lll determination is performed using a pair of placed transmitting and receiving coils, the configuration is in the cylinder, there are fewer restrictions on the measurement site, and an NMR device that does not put psychological pressure on the measurement target has been realized. be done.

[Brief explanation of drawings]

The accompanying drawings are schematic diagrams showing the configuration of an embodiment of the present invention.

Claims (1)

[Claims] A magnet that has an end that can be close to the measurement target and applies a magnetic field in one direction to a specific part of the measurement target that the end faces, and a high frequency wave in a direction substantially orthogonal to the magnetic field applied to the specific part. a pair of transmitter/receiver coils placed across the ends to apply a magnetic field to the specific portion; a transmitter circuit for supplying observation pulses to the transmitter/receiver coils; 1. A nuclear magnetic resonance apparatus comprising a receiving circuit to which a resonance signal is supplied.