JPS6210482B2 - - Google Patents
Info
- Publication number
- JPS6210482B2 JPS6210482B2 JP56088860A JP8886081A JPS6210482B2 JP S6210482 B2 JPS6210482 B2 JP S6210482B2 JP 56088860 A JP56088860 A JP 56088860A JP 8886081 A JP8886081 A JP 8886081A JP S6210482 B2 JPS6210482 B2 JP S6210482B2
- Authority
- JP
- Japan
- Prior art keywords
- drug
- contact lens
- pullulan
- eye
- corneal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003814 drug Substances 0.000 claims description 34
- 229940079593 drug Drugs 0.000 claims description 31
- 239000000463 material Substances 0.000 claims description 16
- 229920001218 Pullulan Polymers 0.000 claims description 14
- 239000004373 Pullulan Substances 0.000 claims description 14
- 235000019423 pullulan Nutrition 0.000 claims description 14
- 239000012530 fluid Substances 0.000 claims description 6
- 230000001225 therapeutic effect Effects 0.000 claims description 5
- 229920002472 Starch Polymers 0.000 claims description 4
- 235000019698 starch Nutrition 0.000 claims description 4
- 239000008107 starch Substances 0.000 claims description 4
- 210000002919 epithelial cell Anatomy 0.000 claims description 3
- 230000008929 regeneration Effects 0.000 claims description 3
- 238000011069 regeneration method Methods 0.000 claims description 3
- 238000004090 dissolution Methods 0.000 claims description 2
- 210000001508 eye Anatomy 0.000 description 16
- 230000000052 comparative effect Effects 0.000 description 8
- 239000007864 aqueous solution Substances 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 208000021921 corneal disease Diseases 0.000 description 5
- 238000001035 drying Methods 0.000 description 5
- 229960002139 pilocarpine hydrochloride Drugs 0.000 description 5
- RNAICSBVACLLGM-GNAZCLTHSA-N pilocarpine hydrochloride Chemical compound Cl.C1OC(=O)[C@@H](CC)[C@H]1CC1=CN=CN1C RNAICSBVACLLGM-GNAZCLTHSA-N 0.000 description 5
- 206010027646 Miosis Diseases 0.000 description 4
- 230000003547 miosis Effects 0.000 description 4
- 210000005252 bulbus oculi Anatomy 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 210000000744 eyelid Anatomy 0.000 description 3
- 239000008213 purified water Substances 0.000 description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 239000003732 agents acting on the eye Substances 0.000 description 2
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 description 2
- 229960005091 chloramphenicol Drugs 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 239000003889 eye drop Substances 0.000 description 2
- 229940012356 eye drops Drugs 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 229940023490 ophthalmic product Drugs 0.000 description 2
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 1
- 208000028006 Corneal injury Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002009 allergenic effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 229960002344 dexamethasone sodium phosphate Drugs 0.000 description 1
- PLCQGRYPOISRTQ-FCJDYXGNSA-L dexamethasone sodium phosphate Chemical compound [Na+].[Na+].C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)COP([O-])([O-])=O)(O)[C@@]1(C)C[C@@H]2O PLCQGRYPOISRTQ-FCJDYXGNSA-L 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000010220 ion permeability Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 210000003786 sclera Anatomy 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
Landscapes
- Eyeglasses (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56088860A JPS57203440A (en) | 1981-06-11 | 1981-06-11 | Treating tool |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56088860A JPS57203440A (en) | 1981-06-11 | 1981-06-11 | Treating tool |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57203440A JPS57203440A (en) | 1982-12-13 |
| JPS6210482B2 true JPS6210482B2 (cs) | 1987-03-06 |
Family
ID=13954744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56088860A Granted JPS57203440A (en) | 1981-06-11 | 1981-06-11 | Treating tool |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57203440A (cs) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0617283U (ja) * | 1991-07-01 | 1994-03-04 | 船井電機株式会社 | 電気機器 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9712824A (pt) * | 1996-09-13 | 1999-12-21 | Advanced Medicine Research Ins | Composição oftálmica de fator neurotrófico, agente de tratamento de desordem funcional do nervo ótico e método para tratamento de desordem funcional do nervo ótico |
| US7795203B2 (en) * | 2002-09-30 | 2010-09-14 | Babizhayev Mark A | Method for topical treatment of eye disease and composition and device for said treatment |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53105251A (en) * | 1976-11-26 | 1978-09-13 | American Optical Corp | Hydrogel contact lens and complex composite for production |
| JPS5545097A (en) * | 1978-09-25 | 1980-03-29 | Dow Corning | Contact lense |
-
1981
- 1981-06-11 JP JP56088860A patent/JPS57203440A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53105251A (en) * | 1976-11-26 | 1978-09-13 | American Optical Corp | Hydrogel contact lens and complex composite for production |
| JPS5545097A (en) * | 1978-09-25 | 1980-03-29 | Dow Corning | Contact lense |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0617283U (ja) * | 1991-07-01 | 1994-03-04 | 船井電機株式会社 | 電気機器 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS57203440A (en) | 1982-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4287175A (en) | Contact lens wetting agents | |
| Hillman | Management of acute glaucoma with pilocarpine-soaked hydrophilic lens. | |
| US3870791A (en) | Solid state ophthalmic medication delivery method | |
| CN105411740B (zh) | 环形装置 | |
| US7036928B2 (en) | Remedy for dry eye syndrome | |
| JPS6122975B2 (cs) | ||
| JP2002540846A (ja) | 投薬または潤滑を局所的に供給するための改良された結膜インサート | |
| US8298595B2 (en) | Contact lens, method for producing same, and pack for storage and maintenance of a contact lens | |
| CA2211376C (en) | Bio-erodible ophthalmic shield | |
| JP2008520671A (ja) | 眼科用組成物および眼の治療方法 | |
| CA2849366A1 (en) | Compositions and methods for treating presbyopia, mild hyperopia, and irregular astigmatism | |
| JP2019504855A (ja) | 非侵襲性眼内薬物送達技法 | |
| Karthikeyan et al. | The concept of ocular inserts as drug delivery systems: An overview | |
| US7169406B2 (en) | Growth factor delivery systems for the healing of wounds and the prevention of inflammation and disease | |
| Ueno et al. | Ocular pharmacology of drug release devices | |
| US4180308A (en) | Contact lens | |
| WO2014192853A1 (ja) | 環状デバイス | |
| US20050085758A1 (en) | Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease | |
| JPS6210482B2 (cs) | ||
| RU2359658C1 (ru) | Средство для профилактики и лечения офтальмологических заболеваний | |
| US4401372A (en) | Contact lens | |
| EP3435971B1 (en) | Amniotic or placental preparation and device for ophthalmic use as a dressing to enhance healing | |
| Khan et al. | Ocular inserts-a novel approach in ocular drug delivery | |
| AQUAVELLA | Therapeutic uses of hydrophilic lenses | |
| Pavičić-Astaloš et al. | Eye drops preservative as the cause of corneal band keratopathy in long-term pilocarpine hydrochloride treatment |