JPS6161819B2 - - Google Patents
Info
- Publication number
- JPS6161819B2 JPS6161819B2 JP21045182A JP21045182A JPS6161819B2 JP S6161819 B2 JPS6161819 B2 JP S6161819B2 JP 21045182 A JP21045182 A JP 21045182A JP 21045182 A JP21045182 A JP 21045182A JP S6161819 B2 JPS6161819 B2 JP S6161819B2
- Authority
- JP
- Japan
- Prior art keywords
- applicator
- electrode
- outer envelope
- heating
- cooling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000010438 heat treatment Methods 0.000 claims description 16
- 238000002513 implantation Methods 0.000 claims description 4
- 238000001727 in vivo Methods 0.000 claims description 3
- 238000000015 thermotherapy Methods 0.000 claims description 2
- 239000002826 coolant Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 11
- 229910052802 copper Inorganic materials 0.000 description 11
- 239000010949 copper Substances 0.000 description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 7
- 238000001816 cooling Methods 0.000 description 7
- 238000010586 diagram Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000006698 induction Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000012809 cooling fluid Substances 0.000 description 1
- 239000000110 cooling liquid Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000009217 hyperthermia therapy Methods 0.000 description 1
- 229910001338 liquidmetal Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 208000006379 syphilis Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Electrotherapy Devices (AREA)
- Radiation-Therapy Devices (AREA)
Description
【発明の詳細な説明】
本発明は温熱治療における有効な生体加熱を行
うためのアプリケーターに関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an applicator for effective biological heating in thermotherapy.
温熱治療法は、人体の一部又は全部を約42℃の
温度に加熱し各種の病気や悪性腫瘍を治療する方
法で、癌ばかりでなく乾癬、梅毒、風邪など多く
の疾患に対して有効であることが基礎医学的諸研
究により確認されており、現在臨床上の有効性の
確認が追試されているところである。 Hyperthermia therapy is a method of heating part or all of the human body to a temperature of approximately 42°C to treat various diseases and malignant tumors, and is effective against many diseases such as psoriasis, syphilis, and colds, as well as cancer. This has been confirmed through basic medical research, and additional tests are currently being conducted to confirm clinical effectiveness.
加熱方式にはマイクロウエーブ照射、高周波誘
導、磁場加温、超音波加温などの局所加温法を初
めとしいろいろな加温法があるが、人体深部の癌
組織部位を他の正常部位に火傷を起さずに加温す
るにはエネルギーを人体に注入するアプリケータ
ー部分に工夫を必要とする。 There are various heating methods, including local heating methods such as microwave irradiation, high-frequency induction, magnetic field heating, and ultrasonic heating. In order to heat the body without causing heat damage, the applicator part that injects energy into the human body needs to be devised.
本発明はこのような加温方式のうち特に高周波
誘導加熱に関して実施されたものであるが、これ
に限定されるものではない。 Although the present invention has been implemented in particular with respect to high frequency induction heating among such heating methods, it is not limited thereto.
高周波加熱アプリケーターとしては、すでに発
明者は実願昭57―110561(実開昭59―14613号)、
実願昭57―132227(実開昭59―36322号)などに
基づき臨床上の種々の状況において有効加熱ので
きる有用なアプリケーターの試作実験を行つてき
たが、このほど生体内に植込み加温治療後抜去す
る機能を有するアプリケーターを製作し、種々の
実験例を行つた結果、臨床上有効かつ有用である
との結論がえられたので、ここに特許出願をする
ものである。 As a high-frequency heating applicator, the inventor has already filed Utility Application No. 57-110561 (Utility Model Application No. 59-14613),
Based on Utility Model Application No. 57-132227 (Utility Model Application No. 59-36322), we have been conducting prototype experiments on a useful applicator that can perform effective heating in various clinical situations. As a result of manufacturing an applicator with a pull-out function and conducting various experiments, we concluded that it is clinically effective and useful, so we are hereby filing a patent application.
生体内アプリケーターは、体表面アプリケータ
ーに比し、小電力で局所を加温できるばかりでな
く、とくに体腔内臓器に対しては、体表面から行
う場合に比べてはるかに正確、有効に加温を可能
ならしめるものである。 Compared to body surface applicators, in-vivo applicators can not only heat localized areas with less power, but also can heat organs within body cavities much more accurately and effectively than when heating from the body surface. It makes it seem possible.
また、このような生体内アプリケーターを加温
治療終了後に手術によらずとりだすことのできる
構造体とすることは、治療上、最も望ましいこと
であり、これによつて加温療法の適応範囲を大幅
に拡大できるものである。 In addition, it is most desirable from a therapeutic perspective to make such an in-vivo applicator a structure that can be removed without surgery after the completion of heating therapy, and this will greatly expand the scope of application of heating therapy. This can be expanded to.
本発明を以下実施例にそつて詳説する。 The present invention will be explained in detail below with reference to Examples.
第1の実施例(第1図及び第2図示)はチユー
ブ渦巻き型アプリケーターであり、薄壁、軟質
PVCチユーブからなる外包1の中に可屈性の密
な銅コイルからなる電極2を全長にわたつて挿入
し、銅コイルには通電と同時に図上、矢標で示す
ように冷却用食塩水の送り込みを併せて行わし
め、銅コイル外側のPVCチユーブを介して冷却
用食塩水を抜きだすものである。この場合、渦巻
き型の頭部が植込部位に密着して有効な加温を可
能にすると共に、治療終了後にそのまま引抜き除
去することができる。 The first embodiment (shown in Figures 1 and 2) is a tube spiral applicator with a thin-walled, soft
An electrode 2 made of a flexible dense copper coil is inserted over its entire length into an outer envelope 1 made of a PVC tube, and at the same time the copper coil is energized, a saline solution for cooling is applied as shown by the arrow in the figure. This is done at the same time as feeding, and the cooling saline solution is extracted through a PVC tube outside the copper coil. In this case, the spiral-shaped head closely contacts the implantation site to enable effective heating, and can be pulled out and removed as is after treatment is completed.
第2の実施例(第3図及び第4図示)は薄壁の
導電性ゴムサツクからなる外包3の中に、渦巻き
型に可屈性の密巻銅コイルからなる電極4を巻き
こんだものであり、やはり銅コイルは通電と冷却
用食塩水の送り込みに用い、サツクを送り出し口
とする構造である。この場合、治療終了後、まず
渦巻き型の電極4を外包3から抜き出し、その
後、外包3を植込部位から除去することができ
る。第3の実施例(第5図示)は薄いアルミ板か
らなる電極5を導電性ゴムサツクからなる外包6
につつみ込み、冷却用食塩水の送り込み口8、送
り出し口8′を設け、一方の流路内には導線7を
通して電極5に接続する。このような構造のアプ
リケーターではこのままでは抜去できないが、希
酸を流してアルミ板5を溶かしてしまえば、ゴム
製サツク6は容易に抜去することができる。 In the second embodiment (shown in FIGS. 3 and 4), an electrode 4 made of a flexible close-wound copper coil is wound in a spiral shape in an outer envelope 3 made of a thin-walled conductive rubber sac. The structure is such that the copper coil is used to supply electricity and feed the saline solution for cooling, and the sac serves as the outlet. In this case, after the treatment is completed, the spiral electrode 4 can be first extracted from the outer envelope 3, and then the outer envelope 3 can be removed from the implantation site. In the third embodiment (shown in the fifth figure), an electrode 5 made of a thin aluminum plate is wrapped in an outer envelope 6 made of a conductive rubber sac.
An inlet 8 and an outlet 8' for cooling saline are provided, and a conductive wire 7 is passed through one of the channels to connect to the electrode 5. Although the applicator having such a structure cannot be removed as it is, if the aluminum plate 5 is melted by flowing dilute acid, the rubber sac 6 can be easily removed.
第4の実施例(第6図示)では薄い導電性ゴム
サツクからなる外包9内に冷却用食塩水を注入す
るための銅パイプ型の電極10を配し、銅パイプ
に通電をほどこすわけであるが、これだけでは、
有効電極面積が不足し、十分な誘電電流を流せな
いので、液体の金属である水銀などを冷却液とし
て循環させることにより、十分な加温特性をえる
ことができる。この場合も治療終了後、銅パイ
プ、冷却液とともに外包を抜き取ることができ
る。さらに第5の実施例では第4の実施例の導電
性ゴムサツク9の代わりに生体に吸収分解される
コラーゲン膜を使用した。このサツクは抜去性の
ある軟らかいものではないが、使用後何カ月かた
つと人体の酵素により吸収分解されており、抜去
したのと同様の効果があつた。 In the fourth embodiment (shown in the sixth figure), a copper pipe-shaped electrode 10 for injecting the cooling saline solution is placed inside an outer envelope 9 made of a thin conductive rubber sac, and the copper pipe is energized. However, with this alone,
Since the effective electrode area is insufficient and a sufficient dielectric current cannot flow, sufficient heating characteristics can be obtained by circulating a liquid metal such as mercury as a cooling liquid. In this case as well, the outer envelope can be removed along with the copper pipe and cooling fluid after the treatment is complete. Furthermore, in the fifth embodiment, a collagen membrane that is absorbed and decomposed by the living body was used in place of the conductive rubber sack 9 of the fourth embodiment. Although this sutsuku is not soft enough to be removed, it is absorbed and broken down by enzymes in the human body several months after use, and has the same effect as if it were removed.
第1図は本発明アプリケーターの第1の実施例
を示す概略説明図、第2図はその一部拡大断面
図、第3図は第2の実施例を示す概略説明図、第
4図はその一部拡大断面図、第5図は第3の実施
例を示す概略説明図であり、第6図は第4及び第
5の実施例を示す概略説明図である。
1:外包となる軟質PVCチユーブ、2:電極
となる銅コイル、3:外包となる導電性ゴムサツ
ク、4:電極となる銅コイル、5:電極、6:外
包となる導電性ゴムサツク、7:導線、8:冷却
用食塩水送り込み口、8′:冷却用食塩水送り出
し口、9:外包となる導電性ゴムサツク、10:
銅パイプ。
FIG. 1 is a schematic explanatory diagram showing the first embodiment of the applicator of the present invention, FIG. 2 is a partially enlarged sectional view thereof, FIG. 3 is a schematic explanatory diagram showing the second embodiment, and FIG. A partially enlarged sectional view, FIG. 5 is a schematic explanatory diagram showing the third embodiment, and FIG. 6 is a schematic explanatory diagram showing the fourth and fifth embodiments. 1: Soft PVC tube as outer envelope, 2: Copper coil as electrode, 3: Conductive rubber sac as outer envelope, 4: Copper coil as electrode, 5: Electrode, 6: Conductive rubber sac as outer envelope, 7: Conductive wire , 8: Cooling saline solution inlet, 8': Cooling saline solution outlet, 9: Conductive rubber sac serving as outer package, 10:
copper pipe.
Claims (1)
を内包し、且つ内部を冷却媒体が循環する状態で
植込部位に密着するアプリケーター外包を有する
局所加温用アプリケーターにおいて、前記電極及
びアプリケーター外包が、機械的、化学的、物理
的あるいは生理学的処置により、植込部位より抜
去あるいは除去可能であることを特徴とする抜去
可能な生体内植込アプリケーター。1. A local heating applicator that includes an electrode with high electrical conductivity used for thermotherapy and has an applicator outer envelope that closely contacts the implantation site with a cooling medium circulating inside, wherein the electrode and the applicator outer envelope are A removable in-vivo implantable applicator characterized in that it can be extracted or removed from an implantation site by mechanical, chemical, physical, or physiological treatment.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21045182A JPS59101146A (en) | 1982-11-30 | 1982-11-30 | Removable in-vivo implant applicator |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21045182A JPS59101146A (en) | 1982-11-30 | 1982-11-30 | Removable in-vivo implant applicator |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS59101146A JPS59101146A (en) | 1984-06-11 |
JPS6161819B2 true JPS6161819B2 (en) | 1986-12-27 |
Family
ID=16589543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP21045182A Granted JPS59101146A (en) | 1982-11-30 | 1982-11-30 | Removable in-vivo implant applicator |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS59101146A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0511882Y2 (en) * | 1987-01-06 | 1993-03-25 |
-
1982
- 1982-11-30 JP JP21045182A patent/JPS59101146A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS59101146A (en) | 1984-06-11 |
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