JPS6158654A - Tape for stabilizing denture - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION Field of the Invention The present invention relates to a denture stabilizing tape with cushioning properties.

BACKGROUND OF THE INVENTION As people age, dentures often loosen due to jaw atrophy and do not fit properly into the gums. Various cream-like products containing vaseline, sodium carboxymethyl cellulose, etc. as main ingredients are commercially available as denture adhesives for such cases, but they may flow out with saliva during use and may not be as effective as they should be. Ta.

Additionally, these products had problems such as being cumbersome to operate, requiring some getting used to, in some cases being unable to eat or drink until several hours had passed after being worn, and being unable to be used if there was inflammation in the gums or cavity 11. .

OBJECTS OF THE INVENTION It is an object of the present invention to provide a denture stabilizing tape that solves the above-mentioned problems and has a cushioning effect that can be used for a long time in extremely comfortable conditions.

DESCRIPTION OF THE INVENTION The present invention is a denture stabilizing tape of a novel form, which is completely different from the conventional denture stabilizer on a ream. That is, the present invention uses stretchable cloth, nonwoven fabric, plastic film, etc., or those coated with an adhesive as a base material, and -1- coats it with a mucosal adhesion agent containing a wood-philic gel as a main component. 461. This is a denture stabilizing tape consisting of: If necessary, an anti-inflammatory analgesic may be added to the adhesive or mucoadhesive.

The components of the present invention will be explained in more detail.

(Substrate) Suitable substrates include stretchable fabrics, nonwoven fabrics, plastic films and foams thereof, composites thereof, and collagen. Moreover, those coated with an adhesive are also used. The reason for applying the adhesive is to effectively adhere the mucoadhesive layer to the base material and to strengthen the cushioning effect on the denture.

As the adhesive, common rubber adhesives, acrylic adhesives, silicone adhesives, etc. can be used.

(Mucoadhesives) Examples of mucoadhesives include cellulose derivatives such as methyl acrylate and hydroxypropyl cellulose, karaya gum, sodium alginate, propylene glycol alginate, and alginate alkyl esters (having 4 to 18 carbon atoms).
Synthetic water-soluble polymers such as polysaccharides such as polysaccharides, polyvinyl alcohol, lithium polyacrylate, and polyvinylpyrrolidone are used.

Indomethacin is an anti-inflammatory analgesic.

Nclofenac sodium and the like are preferred.

EXAMPLES Next, the present invention will be explained with reference to examples, but the present invention is not limited thereto.

Example 1 EVA with a thickness of 30 gm (vinyl acetate content, approximately 1O%)
Propylene glycol alginate [Product name: Kimiloid M,
A 5% aqueous solution (manufactured by Kimitsu Chemical Industry Co., Ltd.) was applied and dried to form a mucoadhesive layer with a thickness of about 10 gm. This was punched out into an oval shape with a width of 2 cm and a length of 4 cm, a mucoadhesive layer was glued to the gums, and a denture that had become loose after long-term use was placed on top of it. It fitted well and remained in place for a long time ( (I was able to do that.

Example 2 20 g of algin and 36 g of n-dodecyl alcohol
・Using 0.5 g of para-toluene sulfonic acid in 200 g of toluene as a catalyst, react in a nitrogen atmosphere at 110°C for 12 hours, and purify the contents by pouring them into 1 sentence of n-hegosan.
Approximately 23 g of dodecyl alginate was obtained. 10 g of this dodecyl alginate was dissolved in 200 g of distilled water, coated on a glass plate at a coating weight of about 20 g/m' after drying, and dried.

Next, 80 g of 2-ethylhexyl acrylate, vinyl acetate Log, 6 g of methyl acrylate, and 4 g of acrylic acid were heated at 60°C at 12°C in a nitrogen atmosphere in the presence of 0.2 g of benzoyl peroxide using 200 g of ethyl acetate as a solvent.
Vertical polymerization was performed.

20 g of the purified copolymer obtained by purifying the obtained copolymer was
g of ethyl acetate], and a solution of 13 g of indomethacin dissolved in 40 g of acetone under heating was added and stirred. This adhesive liquid was applied to a polyurethane film having a thickness of 70 pL·m so that the solid content after solvent volatilization was 50 g/m', and dried. This was pasted onto the mucoadhesive surface of a glass plate coated with the mucoadhesive described above and peeled off to obtain an indomethacin-containing denture stabilizing tape. As a result of the analysis, crystal 1
cm' contained 0.3 mg of indomethacin.

When a crystal was pasted on the painful gums and a denture was placed on top of it, the pain was well suppressed and the denture could be used for a long time without any inconvenience.

Example 3 20 g of alginic acid and 28 g of n-octyl alcohol were reacted in 200 g of toluene with 0.5 g of para-toluenesulfonic acid as a catalyst in a nitrogen atmosphere at 110°C for 12 hours, and the contents were dissolved in 1 l of n-hexane. After purification, about 22 g of octyl alginate was obtained. 10 g of this octyl alginate was dissolved in 200 g of distilled water and applied to a 20 Bm thick polyethylene laminated nonwoven fabric with a basis weight of 40 g so that the coating amount after drying was approximately 15 gm.
It was dried to obtain a denture stabilizing tape.

Similarly to Example 1, the crystal was also able to stably fix the denture for a long period of time.

Effects of the Invention The denture stabilizing tape of the present invention has an excellent feature of having both cushioning properties and adhesive properties by combining a flexible and stretchable base material and a mucoadhesive agent. By applying the crystal to the gums in a very precise manner, the denture can be stably fixed for a long period of time. In addition, when you have severe pain in the gums, gum pain, etc., using a compound containing the anti-inflammatory analgesic of the present invention will also have the effect of alleviating the pain.

Claims (2)

[Claims] (1) A tape for denture stabilization, which has a base material made of stretchable cloth, nonwoven fabric, plastic film, or a material coated with an adhesive, and a mucoadhesive agent containing a hydrophilic gel as a main component is coated thereon. (2) The tape for denture stabilization according to claim 1, which contains an anti-inflammatory analgesic agent in the adhesive or mucoadhesive.