JPS61502726A - Techniques for forming arterial curves related to an individual's blood pressure - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed description of the invention] Techniques for forming an arterial curve related to an individual's blood pressure The present invention generally relates to a blood pressure evaluation method. , particularly non-invasive techniques for forming arterial curves related to blood pressure in one individual. .

The most reliable method currently known for obtaining information about an individual's blood pressure. methods that do not require invasive procedures, such as those during heart surgery. It is carried out under such extreme conditions. Unless the conditions are too strict, especially for one individual. Non-invasively obtaining blood pressure information including systolic (maximum) and diastolic (minimum) blood pressure Can be done. Two well-known non-invasive techniques are in use today: One is commonly referred to as auscultation, and the other is based on vibrometry. It is. These non-invasive techniques use the standard arm A cuff is used. However, in the auscultation method, the cuff is first pressurized and then depressurized. By listening to the sound of seeds (Korotkoff sounds) produced by pressure. Systolic and diastolic blood pressure is measured, whereas in oscillometric methods the cuff is first inflated. Then, the change in cuff pressure caused by the change in blood pressure when decompressing is actually measured. It will be done.

As will become clear below, various embodiments of the invention are based on vibrometry. It is. To fully understand these examples, to obtain blood pressure information non-invasively. No. 3,903,872 (the Link patent).

The patents taken by reference are based on, inter alia, the technology detailed below. A method of obtaining an individual's diastolic blood pressure is disclosed.

Also incorporated by reference are U.S. Pat. Nos. 4,009,709 and 4. ．． 074 , No. 711 (Link et al.) uses vibrometry to obtain an individual's systolic blood pressure. A non-invasive technique for this purpose is disclosed. These techniques are discussed below. Ru.

The above-mentioned patents of Mr. Link and Mr. Link et al. and other patents owned by the applicant The various procedures disclosed provide a simpler and clearer method for obtaining information of any type for the intended purpose. Our goal is to provide highly reliable technology.

A more particular object of the invention is that of U.S. Pat. No. 3,903,872 and Link et al. A novel simple confidence to form blood pressure related curves corresponding to those stated in the sentence The aim is to provide highly effective technology.

As described in detail below, the above object is achieved by vibrometry. child According to the technique of The cuff is placed on a person, particularly a human being, or generally a mammal (hereinafter referred to as the patient). the patient's systolic blood pressure. Pressure is increased to a certain level, for example, 180 Torr.

This pressure is also believed to completely occlude the patient's artery within the sleeve. after that, Gradually decrease cuff pressure towards zero.

During this time, the cuff is sensitive to (1) blood pressure changes in the patient's arteries and (2) changes in cuff pressure. In combination with the change, the pressure changes continuously in an oscillating state. This step In this case, the cuff pressure can be known at any time, and oscillatory changes in the cuff pressure can be detected by e.g. , can be easily measured with an oscilloscope. These two parameters are By use in conjunction with information obtained from the methods disclosed in the above-mentioned U.S. patents, The above objectives are achieved in a simple and reliable manner using the technology of the present invention described below. can do.

In this regard, this is initially addressed by a pressure cuff, typically 5 inches wide. Note that the arm tissue completely surrounds the 5-inch long artery. Because it is almost incompressible, for example, the volume of an artery changes due to pulsating blood flow. As the air volume changes, the air volume of the air bladder in the cuff adjacent to the arm changes correspondingly. this sky A change in air volume causes a small but accurately measurable pressure change in the air. Ru. Thus, pulsatile changes in cuff bladder pressure result in pulsatile changes in arterial volume. Equality is the essence of vibrometry.

For a more complete understanding of the various techniques of the present invention, FIGS. The background technology will be described in more detail in connection with this.

FIG. 1 (corresponding to FIG. 6 of U.S. Pat. No. 3,903,872) shows a dilation of a patient. Assuming that the initial pressure is 80 Torr, the measured pressure of the cuff is 90 Torr to 8Q Torr. Successive cuff pressure and time pulses (cuff pulse) when changing to r and to 70 Torr. The figure schematically shows the shape of the

Figure 1A corresponds to the cuff pulses in Figure 1 from cuff pressure 160 Torr to zero. 1 schematically shows a series of all Cub pulses.

Figure 2 shows the arterial volume, that is, the cuff volume (■), in other words, the patient's blood pulse inside the cuff. volume (measured by the volume of the cuff) and wall pressure (Pν) across the artery wall within the cuff. ) and the curve that represents the relationship between.

Superimposed on this curve is a curve corresponding to the patient's actual blood pressure waveform. These two curves are intended to explain the principle of the vibration measurement method based on the above patent. It is.

Figures 3 and 4 are based on the above-mentioned Link patent and Link et al. patent. The first in a manner that represents the technique for obtaining a given systolic and diastolic blood pressure of a patient. 1 schematically shows the cuff curve of the figure.

Figure 5 shows the compliance curve of the patient's artery, that is, the ratio to the arterial wall pressure Pw. This diagram schematically shows a curve representing ΔV/ΔP, where ΔV is a given constant change in blood pressure. is the incremental change in arterial volume corresponding to ΔP. This curve becomes clear below As shown in Figure 2, the cuff volume, that is, the artery volume curve (V/P curve) is formed by integration. In order to do so, it is determined first.

First, let us explain Figure 1. This figure shows three different cuff pressures, especially 90T. orr, the capacity of the above pressurizing force at cuff pressures of 80 Torr and 70 Torr Figure 1 schematically shows three successive waveforms 10h, 101 and 10j corresponding to product changes; There is. In fact, as is clear from Figure 1A, from a cuff pressure of 160 Torr, A large number of waveforms (hereinafter referred to as cuff pulses) starting at zero cuff pressure is generated. By generating these waveforms at known cuff pressures, patient Systolic and diastolic blood pressure can be measured according to the above patent. About this This will be explained in detail below, but first, each waveform has the rise of systole at one end. Sr, with a diastolic fall Dd at the opposite end and a maximum amplitude A It is important to pay attention to this.

The systolic rise Sr is very consistent and varies from one cuff pulse 10 to another. The diastolic fall Dr and amplitude A are as follows: It varies from pulse to pulse for reasons stated. Disclosed in the above-mentioned patents of Mr. Link and Mr. Link et al. It is because of these changes that diastolic and systolic blood pressure can be measured using the developed technique. It is something that In particular, it is clear that the patient's diastolic blood pressure is equal to the cuff pressure. When the diastolic fall of the generated cuff pulse is different from any other cuff pulse. The slope is steeper than the diastolic fall of . Therefore, the fall of diastole is shown in Figure 1. Assuming the maximum slope at cuff pulse 10i, these waveforms can be The number of patients affected is 80. will have a diastolic blood pressure of rr. At the same time as this , find which cuff pulse has the maximum amplitude A, then increase the cuff pressure. By finding the cuff pulse that is half the amplitude of the patient's systolic blood pressure can be measured. The cuff pressure to generate this hand amplitude pulse is , which is equal to the patient's systolic blood pressure. Figures 2 through 5 will now be explained along with the patents of Mr. Nk and Mr. Link et al.

Now, to explain why the cuff pulse shown in Figure 1 occurs due to changes in cuff pressure. To explain the curve shown in FIG. 2, the generally S-shaped curve shown in FIG. 12 is the wall pressure P across the patient's artery wall within the limits of the attached cuff. The volume of the artery within the cuff, where the horizontal axis represents w and is measured by the internal volume of the cuff itself. It is shown in a horizontal/vertical coordinate system with the vertical axis representing the product V. child In order to fully understand the V/P curve (hereinafter simply referred to as the artery or cuff curve), , Pw is important to keep in mind. The wall of a patient's artery at a given time The pressure Pw is the blood pressure pb in the patient's artery at that time minus the pressure Pc applied by the cuff. is equal to . Therefore, it becomes as follows.

Pw-Pb-Pc (1) For purposes of illustration, pressure shall be measured in T'orr(am)Ig) and vertical The horizontal axis section to the right of the axis represents positive wall pressure, while the horizontal axis section to the left of the vertical axis Let minutes represent negative wall pressure. As a result, no pressure is applied to the cuff (e.g. For example, Pc=O) sometimes.

The pressure Pw at any point in time will be equal to the patient's blood pressure at that time.

When the cuff is pressurized, the pressure Pw decreases (moves to the left along the horizontal axis).

When the cuff pressure Pc is equal to the blood pressure pb at a given time, then the current pressure P w equals zero (eg, vertical axis). At some point, the cuff pressure will lower your blood pressure. When the pressure increases beyond the limit, the pressure Pw at that time becomes negative (moving further to the left on the horizontal axis). do).

Remembering the definitions of the vertical axis V and the horizontal axis Pw, the generally S-shaped The interpretation of the cuff curve 12 will be explained.

We assume that this curve represents the characteristics of the particular patient being diagnosed. Ru. That is, the volume of the patient's artery within the cuff, and by extension the cuff itself, follows this S-shaped curve. Assuming that it changes along this curve and changes only along this curve as Pw changes. Set.

Hereinafter, with regard to FIG. Therefore, for the time being, in FIG. Assume that the arterial curve shown corresponds to a patient consisting of:

With the above explanation in mind, the arterial curve of FIG. 2 will be discussed below. First of all, Assume that no pressure is applied to the patient's cuff, so Pc is zero. This results in Pressure Pv becomes equal to patient's blood pressure Pb. In this regard, blood pressure pb is The point at which the diastolic blood pressure Pb (D) and the systolic blood pressure Pb (s) change over time It is important to be careful. For purposes of illustration, these values are known and, in particular, the expansion of the patient Assume that the systolic blood pressure is 80 Torr and the systolic blood pressure is 120 Torr. subordinate Therefore, when no pressure is applied to the cuff, the pressure Pw is equal to Pb(D) and pb(s ), that is, between 80 Torr and 120 Torr. move. This 40 Torr measurement band is shown by the dotted line 14 in FIG. which actually represents the patient pulse pressure ΔP, which in this case is equal to 40 Torr. There is.

The patient's actual blood pressure waveform 15 is V/Pw in FIG. 2 within the pulse pressure band 14. Superimposed on the coordinate system. As you can see, this waveform is a series of real blood It consists of pressure pulses 16, each pulse corresponding to one beat of the patient's heart. There is.

Each pulse starts at a minimum pressure (the patient's diastolic pressure) and begins at the onset of systole. It increases sharply along the tip, which is Sr, and eventually.

The maximum pressure (the patient's systolic blood pressure) is reached and from there the dicrotic notch and dilatation occur. The pressure decreases along the rear end including the initial fall Dd, and becomes the minimum pressure again. these times At point, when the patient's blood pressure is at its minimum value (i.e., at the extended end of pulse 16), The volume of the patient's artery, and therefore the volume of the cuff, is determined by the arterial curve as V1 (P v = 80). On the other hand, the patient's blood pressure is the maximum value (each blood pressure pattern When the arterial curve is at the constricted end of the curve 16), the arterial volume and thus the cuff volume is fixed at a slightly higher value denoted by V2 (Pv=L20). Therefore, each heart If we assume that the cuff pressure Pc is zero for the heartbeat, the volume V (cuff volume) is the value v1 and vl, thereby causing cuff pressure Pc= as shown in FIG. 1A. A series of cuff pulses 10q corresponding to those shown in FIG. 1 are generated at O. . Therefore, as a patient's blood pressure increases from a minimum to a maximum, the volume of the artery increases. There is a generally corresponding increase from vl to vl, and the patient's blood pressure again and decreases to a minimum value, the arterial volume generally corresponds to vl. decreases from to vl. Therefore, each of the arterial pulses 10 in FIG. Sr and diastolic fall Dd are the systolic rise and diastolic fall of each blood pressure pulse 16. Respond to

Explained how cuff pulse 10q depends on the volume curve at cuff pressure 0 However, how the arterial curve changes the arterial pulse with the application of cuff pressure. explain. Assume here that the cuff pressure is 5QTorr. of these conditions Under the condition, the pressure Pw oscillates back and forth between 30 Torr and 70 Torr.

The value of 30Torr is 50T from the diastolic blood pressure Pb(D) of 8QTorr. determined by subtracting the cuff pressure Pc of orr and 70 Torr Values range from systolic blood pressure pb(s) of 120 Torr to cuff pressure Pc of 50 Torr. Determined by subtracting . Therefore, the entire 40 Torr band is As shown in area 14', it is shifted to the left by an amount equal to 5QTorr. Under these conditions, the pressure Pv increases along the steeper part of the arterial curve. oscillates back and forth, changing the volume of the patient's artery and, by extension, the volume of the cuff to values V3 and v4. oscillate between. This results in an arterial pulse of 101 at a Pc of 50 Torr. is formed. The amplitude of each cuff pulse 101 is greater than the amplitude of each cuff pulse 10q. Please be careful. This is 4QTorr at a turnip pressure of 50Torr. Zone 14' is at a steeper volume slope than zone 14 at zero cuff pressure. It is from. In fact, the cuff pressure Pc is increased and the pressure Pg is decreased), thereby , when moving the pressure band to the left on the horizontal axis, first move along the steep part of the arterial curve. 5 Then, move along the part with a gentle slope. Therefore, against that The amplitude A of the corresponding cuff pulse IOQ, IOL, etc. (see Figures 1 and 1A) is , first increases to a maximum value, then decreases again. When the cuff pressure Pc is 100 In some cases, the entire 40 Torr pressure band spans the same distance on each side of the vertical axis. shifted to the left.

This is indicated by 14". This gives the maximum amplitude (ΔVmax in Figure 2) ) corresponding cuff pulses Log are formed.

For example, when moving further to the left at a cuff pressure Pc of 160 Torr, 40Torr The entire band of rr is shifted by a considerable distance l to the left of the vertical axis, as shown in 14)'', The change in volume (amplitude of the corresponding cuff pulse 10a) becomes very small. cuff pressure By increasing the force to a larger value, the band is moved further to the left, eventually increasing the capacity. The change in the product ■ becomes extremely small. From a physical point of view, this is a blockage in an artery. means. In other words, the cuff pressure is sufficiently higher than the blood pressure pb to collapse the artery wall. A force Pc is applied. In the opposite case, i.e., when the cuff pressure Pc is zero, , no external constraints are imposed on the artery, and the artery is based only on the internal blood pressure Pb. Change back and forth freely. Between these extremes, the amplitude A of the cuff pulse 10 (e.g. , ΔV) increases to a maximum value as described above and then decreases again. Mr. Link above The volume curve used to measure a patient's systolic blood pressure is based on the patents of This characteristic will be explained with reference to FIGS. 3 and 4.

Note, as mentioned above, that as blood pressure increases, arterial volume increases. . This increase in arterial volume reduces the air volume of the cuff bladder, which causes Air pressure in the cuff bladder increases. Therefore, as blood pressure increases, cuff air pressure increases. To increase. This can be summarized as follows.

Increase in blood pressure → increase in arterial volume → decrease in cuff air volume → increase in cuff air pressure Therefore, Increase in blood pressure → Increase in cuff air pressure In FIG. 3, the same arterial curve 12 as in FIG. 2 is shown.

One superimposed pressure band 14'' at a cuff pressure Pc of 120 Torr. have. Now, again, the patient's diastolic blood pressure is 80 Torr and the systolic Assume that the systolic blood pressure is 120 Torr and Pc is equal to the patient's systolic blood pressure. Ru. Under these conditions, the pressure Pw is within zone 14'''' as shown. It oscillates back and forth between -40 Torr and zero pressure. This allows the arterial volume to A change ΔV (e.g., the amplitude A of the corresponding cuff pulse) occurs, which is equal to . The maximum change in volume ΔVmax (and thus the maximum cuff pulse amplitude Amax) is approximately resulting from a cuff pressure Pc of 100 Torr (e.g., pressure zone 14'' in Figure 2). Recall that, therefore, the turnip pressure Pc is equal to the patient's systolic blood pressure pb(s). When the time comes.

The amplitude A of the cuff pulse 10 generated by this is half of the maximum amplitude cuff pulse. It becomes the amplitude. Therefore, the patient's systolic blood pressure is initially, as in Figure 1A, Measured by producing a series of cuff pulses across the cuff pressure vector be able to. From these pulses, the one with the maximum amplitude Amax is determined. , then a cuff with half that amplitude (at higher cuff pressure) The pulse can be found. The cuff pressure Pc used to generate this pulse is Corresponds to the patient's systolic blood pressure. In other words, evaluate the amplitude of various cuff pulses By doing this, we can find the band corresponding to band 14'''' shown in Figure 3. Wear. Once this pulse is seen, the associated cuff pressure is It is considered to be equal to systolic blood pressure. This is US Pat. No. 4,009,70 of Link et al. No. 9 and No. 4°074.711, and in these patents In this case, means are provided to conduct these evaluations electronically.

Returning to FIG. 2, the actual blood pressure waveform 15 is, for example.

It is shown to have a uniform repetition rate of 60 pulses/min.

Note that each blood pressure pulse 16 forming this waveform is identical to the next pulse. I want to be understood. For purposes of explanation, we will assume both of these aspects of the waveform. Furthermore, each part As mentioned above, the pulse has its own systolic rise Sr and diastolic fall Dd. have. In addition, the arterial curve 12 is located at the extreme points of the diastole and systole of each pulse. Not only that, but also the relationship between V and P at each point on the waveform 15 of each blood pressure pulse 16. Please also note that it indicates the person in charge.

Therefore, the change in volume at two separate cuff pressures only along the fall of diastole ΔV can be measured. In this case, the measurement band (e.g. between two measurement points) pressure difference) is substantially narrower than zone 14, as best shown in FIG. ΔVl' is measured for zero cuff pressure Pc using pressure zone 18 and pressure The force band 18 surrounds a small portion of the diastolic fall of each blood pressure pulse 16. be. ΔV2' is a cuff pressure of 50 Torr by shifting the band to 18'. is measured for the force Pc, and ΔV3' shifts the band to 18'' measured against a cuff pressure Pc (e.g., patient's diastolic blood pressure) of 80 Torr. determined. ΔV is at its maximum when the cuff pressure Pc is equal to the patient's diastolic blood pressure. Please be careful. Therefore, the expansion of the patient's actual blood pressure waveform for each cuff pressure is The one that produces the maximum change by measuring the volume change ΔV at the end of the tension ramp. cuff pressure corresponds to the patient's diastolic blood pressure. A portion of each pulse 16 The lowest pressure part of the diastolic falling Dd that forms is.

It is suitable for this purpose as it can be easily searched during each cycle of the waveform. like this What can be easily searched for is the systolic rise Sr, which can be easily distinguished each time it appears. This is because the lowest pressure portion is located immediately before. This procedure can be performed electronically. 3,903,872, as detailed in the aforementioned Link U.S. Pat. No. 3,903,872. It is.

In the above instructions for obtaining the patient's systolic and diastolic blood pressure, the patient's arterial curve is It was assumed that the curves correspond to the curves shown in FIGS. 2, 3, and 4. This way Although such an assumption is valid, it is important to understand the patient's own capacity using the principles related to Figure 4. It is also possible to measure the product curve. In particular, the narrow band 18.18' etc. The volume change ΔV obtained from various cuff pressures Pc (for example, cuff The change in volume) is plotted as shown in FIG. Therefore, cuff pressure Pc is zero, the volume change ΔV is relatively small, which means that the small ΔV in FIG. It is clear from l'. As the cuff pressure Pc increases, the volume change ΔV It continues to increase until it reaches a large value (Δv3' in FIG. 4) and then decreases. to express mathematically Then, this curve shows the incremental change in volume with incremental change in pressure, or dV/dP (5th Figure). By integrating this curve, we can A V/P curve can be obtained.

patient diastole based on the technology disclosed in the aforementioned Link and Link et al. patents. FIGS. 1 to 5 illustrate the known techniques for obtaining systolic blood pressure and systolic blood pressure. However, various features of the present invention will now be described with reference to FIGS. 6 to 9.

Figure 6 shows the peak/peak amplitude of the various Cub pulses of Figure 1A versus cuff pressure. FIG.

7 is a graph showing an arterial curve formed only from the information in FIG.

Figure 8 shows the same curve as Figure 7 but normalized to zero volume at negative wall pressure. Fig. 3 shows a curve on which a differential curve is superimposed.

FIG. 9 is a diagram schematically showing a configuration for electronically forming the curve of FIG. 8.

First, referring to FIGS. 6 to 9 together with FIG. 1A, the arterial curves, or cuff curves, of two individuals are The technique of the present invention for forming lines will be explained. As mentioned above, Figure 1A The cuff pulses 10a, 10b1, etc. of a specific patient read out on the oscilloscope, Starting from cuff pressure of 160 Torr (pulse 10a) to zero cuff pressure (pulse 10a) 10q) for varying cuff pressure (Pc). each cuff pal Note that the peak/peak amplitude (A) of the signal was measured and shown in Figure 1A. As will become clear below, this information and, for example, Mr. Link and The patient's diastolic and systolic blood as determined by a suitable method based on the patent of Link et al. By using only pressure information, a particular patient's own arterial curve or cuff (V /P) curve and the arterial compliance (dV/dP) curve It can be formed by any method.

The graph in Figure 6 shows the peak/peak amplitude values (A) measured from Figure 1A at the cuff. It is plotted against pressure and the resulting curve 4o is shown.

Using the information obtained from this curve and the patient's diastolic and systolic blood pressure, The S-shaped arterial (V/P) curve 42 shown is shaped. How to do this To understand in detail, the patient's diastolic and systolic blood pressure is shown in Figure 2. It is assumed that a pulse pressure zone (e.g. measurement zone) corresponding to the zone 14 is formed. Must be memorized. The patient's diastolic blood pressure is 85 Torr and the systolic blood pressure is 85 Torr. Assuming the blood pressure is 125 Torr, this band is exactly 40 Torr wide. be. Also, as mentioned in Figure 2, the X axis corresponds to Pv (wall pressure of the patient's artery). The arterial curve 42 is then plotted in an x-y coordinate system such that the y-axis represents the relative arterial volume. It must also be noted that the Other points include Pwall ( wall pressure) = Pblood (blood pressure) - Pcuff (cuff pressure), i.e., Pv = It is Pb-Pc. Therefore, when the cuff pressure Pc is zero, the measurement band is 8 between 5 Torr and 125 Torr, and the peak/peak amplitude of the cuff pulse is 0, I Torr, which is the change in arterial volume resulting from this cuff pressure. (ΔV) (directly proportional to).

In other words, if the patient's blood pressure is within the measurement band between 85 Torr and 125 Torr. When rising and falling, ΔV is 0, by an amount directly proportional to I Torr. Change. This point can be plotted as point 1 in FIG.

If the cuff pressure is 40 Torr, 40 Torr between 85 Torr and 45 Torr. The wall pressure Pw oscillates back and forth within the measurement band of Torr. Figures 1A, 6 and 7 As shown in the figure, this results in a peak-to-peak amplitude of Q, 5 Torr. ΔV changes in direct proportion.

This can be plotted as two points. Figure 7 shows the 80.120 and 160 categories. Further points 3.4 and 5 are plotted corresponding to the pressure. only 5 points Although not plotted, all cuff pressures actually measured in Figure 1A In addition to the corresponding points, you can also plot the points interpolated from the curve in Figure 6. Wear. From these points, the artery (V/P) curve 42 shown in FIG. 7 can be easily formed. can do. This curve is also shown in Figure 8, where the axis corresponding to Pw is It has been moved downward as shown. Once the arterial curve is formed, the motion By differentiating the pulse curve, or by using the peak/peak (A) data in Figure 6. Directly from the patient's compliance curve dV/dP, 43. (V/P curve) can be formed. The vibrationally measured cuff pulse amplitude A shown in Figure 1A is , often non-zero for very large values of cuff pressure; approach the value. This small value is shown in the table of Figure 1A and the graph of Figure 6. from each of the amplitude values A. Using the slightly reduced value A resulting from this However, by using the method described above, it is possible to form a slightly improved V/P curve. I can do it. Figure 9 shows one means 44, which is attached to an individual's arm. via a cuff (not shown) and a transducer forming part of means 44. 6 means 44 for receiving various cuff pulses from the individual corresponding to Figure 1A then: The peak/peak information is extracted and the patient's systolic phase is calculated from the appropriate inputs shown in Figure 9. and diastolic blood pressure, it acts on this information to create an arterial V/P curve. 42 and/or dV/dP curve 43, which is a permanent It can also be recorded on an oscilloscope, or typically on an oscilloscope as shown in 46. It can also be displayed. The electronic equipment necessary to make the means 44 function in this manner includes: It can be easily configured using the technology disclosed herein.

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FIG.-2 oPWALL = PBLOOD -PCUFFFIG, -5- One Pi/Beak guys (A3 + To + r + □□□□□□□□□□□□□□□□□ □□□□□□□□□□□□□ Commissioner of the Patent Office Kuro 1) Mr. Akio 1. Indication of case PCT/IJS851011193, person making amendment Relationship to the case: Applicant 5. Date of amendment order: August 5, 1986 Translation of drawings 7. Contents of the amendment as shown in the attached sheet An engraving of the translation of the drawing (no changes to the content) Kunihara YA inspection report Yom--Psu1ne1t-1---alA-C4self--m-11-1+14p cT7us8S101119

Claims (8)

[Claims] 1. In a method of forming a particular mammalian arterial characteristic curve, a) placing a blood pressure cuff around a particular artery of said mammal; b) cooperating with said cuff; the cuff from zero pressure to at least the mammalian systolic blood pressure using means of Pressurize to many different pressure levels up to equal pressure and based on the different pressure levels above. generating a cuff pulse having a peak-to-peak amplitude value corresponding to c) measuring the diastolic and systolic blood pressure of said mammal; and d) measuring said peak/peak. and the above arterial curve in a manner that requires the use of the above diastolic and systolic blood pressures. A method characterized by drawing. 2. Using only the above peak/peak amplitude values and the above diastolic and systolic blood pressure 2. The method according to claim 1, for constructing an arterial curve. 3. In an apparatus for forming a specific mammalian arterial characteristic curve, a) a blood pressure cuff placed around a particular artery of said mammal; b) cooperating with said cuff; the cuff from zero pressure to a pressure at least equal to the mammal's systolic blood pressure. to a number of different pressure levels, based on and based on said different pressure levels; means for generating cuff pulses having peak-to-peak amplitude values corresponding to; c) means for measuring diastolic and systolic blood pressure of said mammal; and d) Requires the use of peak/peak values and diastolic and systolic blood pressures as indicated above. An apparatus characterized in that it comprises means for plotting the arterial curve in a manner similar to that described above. 4. Using only the above peak/peak amplitude values and the above diastolic and systolic blood pressure 4. The device according to claim 3, for plotting an arterial curve. 5. In a method of forming a particular mammalian arterial characteristic curve, a) placing a cuff means near a particular artery of said mammal; b) said cuff means; Using cooperating means, the cuff means is reduced from zero pressure to the mammalian systolic blood pressure. pressurize to a number of different pressure levels up to at least equal pressure; emit a cuff pulse based on the bell and with a corresponding peak/peak amplitude value. live, c) measuring the diastolic and systolic blood pressure of said mammal; and d) measuring said peak/peak. and the above arterial curve in a manner that requires the use of the above diastolic and systolic blood pressures. A method characterized by drawing. 6. Using only the above peak/peak amplitude values and the above diastolic and systolic blood pressure 2. The method according to claim 1, for constructing an arterial curve. 7. In an apparatus for forming a specific mammalian arterial characteristic curve, a) blood pressure cuff means placed near a particular artery of said mammal; b) cooperating with said cuff means to cause said cuff means to discharge systolic blood of a mammal from zero pressure; pressurize to a number of different pressure levels up to a pressure at least equal to the pressure and different above Cuff pallet based on pressure level and with corresponding peak/peak amplitude values a means for generating c) means for measuring diastolic and systolic blood pressure of said mammal; and d) Requires the use of peak/peak values and diastolic and systolic blood pressures as indicated above. An apparatus characterized in that it comprises means for plotting the arterial curve in a manner similar to that described above. 8. Using only the above peak/peak amplitude values and the above diastolic and systolic blood pressure 8. The apparatus of claim 7 for plotting an arterial curve.