JPS61216659A - Nutritive food composition - Google Patents

Abstract

PURPOSE:To obtain a nutritive food composition having improved physiologically active performance such as increase in physical strength, recovery of fatigue, energy promotion, stress elimination, etc., by using octacosanol and pantothenic acid or its salt as active ingredients. CONSTITUTION:A blend comprising 1pt.wt. octacosanol, 0.1-20pts.wt., preferably 0.5-10pts.wt. pantothenic acid or its salt such as sodium pantothenate, and, if necessary, other vitamins as active ingredients is added to various foods, or made into gelatin capsule, tablet, drink agent, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Application Field] The present invention relates to a nutritional food composition having excellent physiologically active abilities such as increasing physical strength, recovering from fatigue, increasing energy and relieving stress.

[Conventional technology]

Many foods have been known to have physiologically active properties, such as pine nut oil, sesame oil, α-lylunic acid, eicosapentaenoic acid, and various vitamins, and are edible in various forms as nutritional and tonic foods. It has been.

In addition, Dr. Creighton of the United States has researched the physiological activity of octacosanol in wheat germ oil and found that octafusar affects energy metabolism in the human body.
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) [Problems to be solved by the invention] Conventional nutritious and tonic foods each have unique physiological activities, but their effects are limited, and it is difficult to expect sufficient effects to increase physical strength and energy. Can not. Furthermore, octacosanol alone has the above effects to some extent, but it is only involved in the energy metabolism stage of the human body and does not act as a coenzyme in the body, so it has sufficient physiological activity. was not obtained.

[Means for solving problems]

The present invention combines octacosanol with other physiologically active substances in order to enhance its excellent physiologically active ability.It has synergistic nutritional effects and physiological activities, and moreover, many people continue to use it. The present invention provides a nutritional food composition in a form that can be ingested.

That is, the present invention is a nutritional food composition containing octacosanol and pantothenic acid or a salt thereof as active ingredients.

Octacosanol used in the present invention is a straight chain aliphatic alcohol having 28 carbon atoms, and the pure product has a melting point of 83C and is a white solid at room temperature. It is contained in ultra-fine amounts of 1 to 100 PPM in naturally occurring plant waxes.

In the present invention, it is economically preferable to use a product obtained by separating and concentrating octacosanol from the above-mentioned waxes and having a purity of 5 to 20%, but it is of course possible to use a product with a higher purity. This low-purity product includes tri-7contanol, a long-chain alfur similar to octacosanol;
It contains tetracosanol, hexacosanol, etc., but they have similar effects, so there is no problem.

In the present invention, octacosanol is mixed with pantothenic acid or a salt thereof, and the mixing ratio thereof is preferably 0.1 to 201 parts by weight, particularly pantothenic acid or a salt thereof, per 1 part by weight of octacosanol. Preferably it is 0.5 to 10 parts by weight.

This amount is 0. If the amount is less than 1 part by weight, the desired effect will not be obtained, and if it exceeds 20 parts by weight, the effect will not increase significantly and the amount of octacosanol will be relatively reduced, which is not preferable. Note that the salts of pantothenic acid used here include, for example, sodium salts, calcium salts, potassium salts, and the like.

It can also be added to salad dressings, mame-naise, margarine, salad oil, soups, biscuits, etc., and served as food, but the forms that are easy for many people to consume continuously are: Preference is given to the forms of gelatin capsules, tablets and drinks.

The nutritional food composition of the present invention may further contain vitamins in addition to the above-mentioned active ingredients. Examples include vitamin A, vitamin B1, vitamin B2, vitamin C, vitamin D, vitamin E, vitamins, and vitamin P.

〔Effect of the invention〕

By using octacosanol and pantothenic acid or its salt in combination, the nutritional food composition of the present invention inhibits the tricarboxylic acid cycle in the body through the coenzyme action of pantothenic acid, that is, the action of this CoA (=enzyme). It synergistically enhances the excellent physiological activity of octacosanol, significantly increasing the efficiency of food energy metabolism, and at the same time, it also effectively works to produce acetylcholine, which is involved in the phlegm system, improving reflexes and responding to stress. Resistance can also be increased. Therefore, according to the present invention, it is possible to obtain a nutritional food composition that has excellent physiologically active effects such as increasing physical strength, recovering from fatigue, increasing energy, and relieving stress due to the synergistic effect of the above-mentioned components.

[Example of real power]

The present invention will be explained below with reference to practical examples.

Example L ddj male Makusu (4 weeks old) 1 #10 animals, 5
After being reared for one day, a physical fitness test was conducted.

Mice were fed a normal diet, their bodies were measured once a day, and the daily doses per 1 kg of body weight were shown in Table 1, and the mice were orally administered.

Warm 1 ton of water from Solution A to 80C, add 0.2 d of emulsifier (Twsen 80, trade name of Near Truss Chemical Co., Ltd.) and stir well. To this, add octafusanol (purity 95) to the following concentration. %) and stirred until the mixture became transparent to obtain liquid A and liquid A2.

Al solution o, o2xq/L A2 solution 0.219/l Preparation of B solution Add calcium pantothenate to the above A, solution and Az solution so that the concentration becomes O, lIP/lK, and make Bi solution respectively. and B2 solution.

(1) Swimming test A constant temperature bath with a water temperature of 25C (40X30
A mouse was made to swim with L5p weights attached to its hind legs, and its condition was observed.

For each mouse in each group, we measured the time it took to submerge its face under the water surface five times, and counted the number of countries in which the mouse had been swimming for up to 10 minutes. The results are shown in Table 1. Ta.

+2) @Tatare durability and movement ability test CI! This test takes advantage of the fact that mice have a habit of moving to the end of a wire when they are hung from a wire by their front legs. That is, the length is 281. Hang the mouse from the center of the wire,
The number of mouse movements that reached the end of the wire by using its own blade to reach the end of the wire was counted, and the results are shown in Table 1. Note that this test was conducted separately from the swimming test described above.

As is clear from the results in Table 1, the 4 and 51F samples treated with octacosanol and calcium pantothenate had better endurance in both the swimming test and the suspension test than those in the comparison group. It is recognized that it is effective in increasing physical strength and recovering from fatigue.

Example 2 Tablets (one tablet per tablet) were manufactured in a conventional manner according to the formulation shown below.

(Composition) (11i per tablet) Octacosanol (purity 12%) SO Calcium pantothenate 20 Vitamin E
15 vitamins 0
100 lactose
100 sorbitol
100 dextrin
300 starch 31
5 Flavor (Grapefruit) Small Meal Example & Gelatin capsules (1 capsule 3811F) were manufactured by a conventional method according to the formulation shown below.

(Composition) (q per capsule) Octafsanol (purity 12%) 20 Sodium pantothenate 20 Vitamin E
25 vitamin A
(100OIU) Nshichi/25 Rice Bran Oil 120 Wheat Germ Oil 130 Flavor (Lemon)
Gelatin capsules (1 capsule 5aoav) were produced by a conventional method according to the formulation shown below.

(Composition) (per capsule) Octafsanol (12% purity) 20 Calcium pantothenate 20 Vitamin E
25 vitamin A
(100OZU) Vitamin D
C100IU) Lecithin
25 cape chain triglyceride 24
0 Flavor (Glaze) Trace Panacetate 810: Nippon Oil & Fats ■Product Name Example
ZooTllll bottled) was produced.

(Composition) (q per xoov) Octacosanol (purity 12%) 4G J-lium pantothenate 10 Vitamin B violet
30 Vitamin C150 Citric Acid 30G Ethi I
7
500 fruits III
3000 lecithin
100 fatty acid ester (emulsifier) Z
o.

Flavor (Orange) Small amount of water
In total! When one to several pieces (units) of the nutritional food composition in the form exemplified above are continuously ingested per day, it exhibits excellent nutritional effects and physiological activity, increasing physical strength, recovering from fatigue, increasing energy, and relieving stress. K11F
A strong effect was observed.
□Patent applicant Nippon Oil & Fats Co., Ltd. Procedural Amendment S (voluntary) April 30, 1985 Manabu Shiga, Director General of the Patent Office (! # Office Examiner! IR) 1 Case Indication Patent Application in 1985! 54389 No. 2, Name of the invention Nutritional food composition 3 Relationship with the case of the person making the amendment Patent applicant 1-10-1 Yurakucho, Chiyoda-ku, Tokyo Column 5 of the detailed description of the invention in the specification, Contents of the amendment

Claims (1)

[Claims] 1. A nutritional food composition containing octacosanol and pantothenic acid or its salt as active ingredients. 2. The nutritional food composition according to claim 1, which contains 0.1 to 20 parts by weight of pantothenic acid or a salt thereof per 1 part by weight of octacosanol. 3. The nutritional food composition according to claim 1 or 2, which further contains other vitamins.