JPS61194012A - Dentifrice composition - Google Patents

Abstract

PURPOSE:The titled composition having improved dispersibility, good feeling in used, capable of being made transparent, obtained by blending a dentifrice composition containing a binder and a surface active agent with a synthetic amorphous zirconium bonded silicate as a polishing agent. CONSTITUTION:A dentifrice composition containing sodium carboxymethyl cellulose, etc. as a binder and an anionic and/or nonionic surface active agent is blended with preferably 1-50wt% based on the total amounts of the composition of a synthetic amorphous zirconium bonded silicate having 0.1-10wt%, especially 0.2-2wt% calculated as Zr based on SiO2 of Zr bonded, preferably 1.40-1.47 refractive index, <=800m<2>/g specific surface area, 1.9-2.3 specific gravity, and 0.4-2.0ml/g liquid absorption amount as a polishing agent, to give a dentifrice composition having middle dispersibility and improved foaming and/or juice effects, capable of being substantially made transparent by letting substantially the polishing agent and a vehicle for dentifrice have the same refractive index.

Description

DETAILED DESCRIPTION OF THE INVENTION Field of Industrial Application The present invention provides a dentifrice composition containing a binder and a surfactant, in which the amount of zirconium bond as an abrasive is 0.1 to 10% by weight in terms of ZrO2 based on SiO2. % synthetic amorphous zirconium-bonded silicate (hereinafter referred to as zirconosilicate). To be more specific, the toothpaste composition has a good feel when used (1), and the dentifrice vehicle is made substantially of the zirconosilicate. The present invention relates to a toothpaste composition that can be made transparent by having the same refractive index.

Prior art and its problems Since dentifrice compositions are used in the oral cavity, they need to have a good feel when used. In particular, one of the important properties is one that has good dispersibility in the mouth and quickly disperses in the oral cavity when used, has good foaming properties, and has a good juice effect.

For this reason, although various proposals have been made for dentifrice compositions that are comfortable to use, there is a desire for a dentifrice composition that is even more comfortable to use, such as dispersibility in the mouth.

In addition, although transparent toothpaste has recently attracted attention, conventional transparent toothpaste uses amorphous silicic anhydride as an abrasive. However, conventional amorphous silicic acid anhydride has poor stability over time, and there is a problem that the transparency of transparent toothpaste decreases during storage.
Therefore, a dentifrice composition that has high stability over time and high transparency is desired.

Summary of the Invention The present applicant previously proposed the use of a synthetic amorphous zirconium-bonded silicate (zolconosilicate) having a zirconium bond content of 0.1 to 10% based on SiO2 in terms of Z ro 2 as an abrasive for tooth brushing. (Special application 1986-15)
No. 3156). This zirconosilicate has a good feeling of use, and when used as an abrasive for a transparent dentifrice composition, this zirconosilicate has a low minimum turbidity and can be stored for a long time at normal temperatures. It has excellent stability over time with little change in refractive index, so the transparency of the toothpaste composition does not easily change even when stored for a long time or in cold or warm regions, so it has excellent transparency stability. Accordingly, it is possible to obtain a dentifrice composition having high transparency. Furthermore, a dentifrice composition containing this dylphosilicate as an abrasive exhibits excellent storage stability. That is, it exhibits good shape retention even when stored at high temperatures for a long period of time, and liquid separation is unlikely to occur.

Moreover, this solconosilicate can be freely manufactured on a rod to have the desired liquid absorption amount by changing the amount of zirconium bonding, and therefore, the zirconosilicate can be freely manufactured without changing the composition of the tooth brushing vehicle. A toothpaste with the desired viscosity can be prepared by simply using a silicate with a desired liquid absorption amount, and a zirconosilicate with excellent blending properties and the desired liquid absorption amount can be used alone or with other silicates. When used in combination with an abrasive base material, it has various advantages such as being able to obtain a dentifrice composition that has appropriate viscosity and can be easily extruded from a container.

The present inventors further investigated this zirconosilicate, and as a result, found that zirconosilicate can be used as a binder, especially as a binder. Sodium oxymethylcellulose, carrageenan,
Cargoxypinyl polymer (crosslinked polyacrylate)
It has been found that when used in combination with one or more of the following, zirconosilicate and these binders are well compatible, and a toothpaste composition with excellent dispersibility and good feeling of use can be obtained.

In addition, calcium hydrogen phosphate and calcium carbonate, which have traditionally been widely used as abrasives for tooth brushing, have to be mixed in a large amount of 40 to 50 violets in order to obtain appropriate polishing power. Since there is a large amount of free calcium ions, it is common practice to add a relatively large amount of anionic surfactant to provide good foaming.
When blending a large amount of anionic surfactant like jin, there are problems such as deterioration of flavor and stability, and to avoid this, consideration must be given to other compositional ingredients from the viewpoint of toothpaste formulation. Ta. However, the present inventors found that when using zirconosilicate as an abrasive, the
Appropriate polishing power can be obtained even with a blending amount of about 100% by weight, and the compatibility of the anionic surfactant with zirconosilicate is good, and it is possible to obtain at least good foaming with the blending amount of the anionic surfactant. I found out.

In addition, zirconosilicate and noni, on surfactants, especially CiMII fatty acid ester, lactose fatty acid ester, lactitol fatty acid ester, multi-l fatty acid ester, maltotriitol fatty acid ester, maltotetriitol fatty acid ester, malthentitol When combined with one or more fatty acid esters, maltohexitol fatty acid esters, malt, heptitol fatty acid esters, and raffinose fatty acid esters, a dentifrice composition with excellent shape retention, mouth dispersibility, and juice effect can be obtained. I discovered that.

In addition, as mentioned above, zirconosilicate is suitably used as an abrasive for transparent toothpaste, and has higher stability over time than conventional silica-based abrasives, with the refractive index of zirconosilicate remaining almost constant even after long-term storage. Since the refractive index does not change, the difference with the refractive index of the transparent toothpaste vehicle hardly increases, and the transparency can be maintained. The present invention was completed based on the above findings.

Therefore, the present invention provides a dentifrice composition containing a binder and a surfactant, in which the zirconium bond amount is Z as an abrasive.
To provide a dentifrice composition characterized in that it contains a synthetic amorphous zirconium-bonded silicate in an amount of 0.1 to 10% by weight based on SiO2 in terms of rO2, and optionally a water-soluble salt. .

The present invention will be explained in more detail below.

Structure of the Invention In the dentifrice composition according to the present invention, a synthetic amorphous zirconium-bonded silicate (norconosilicate) is used as an abrasive.
is used.

The sol fluorosilicate of the present invention usually contains zirconium bonded to SiO2 in the form of ZrO2, and is different from a simple mixture of silicic anhydride and zirconium dioxide or zirconyl hydroxide or from crystalline zirconium silicate.

Here, the SiO2 content in the zirconosilicate is preferably 70% by weight or more, particularly 85% by weight or more, based on anhydrous (S) luconosilicate dried at 105 DEG C. for 2 hours). In addition, the amount of zirconium bonds in zirconosilicate is 5% in terms of liquid absorption, transparency stability, and polishability.
It is necessary that Zr02fi be 0.1 to 10% by weight with respect to to2, and preferably Zr02 with respect to 5IO2.
It is 0.2 to 2 heavier in terms of rO2. If the amount of zirconium bonded is less than 0.1 weight percent in terms of ZrO2, the properties of solconosilicate are not substantially exhibited. Furthermore, if the amount of zirconium bond is more than 10% by weight in terms of Zr02, it becomes difficult to control the physical properties, and this is not preferable as an abrasive base material for transparent toothpaste.

Aluminum, magnesium, sodium, potassium, lithium, hafnium, etc. may be dispersed or combined in zirconosilicate, and these may be impurities from sodium silicate, zirconyl chloride, sulfuric acid, etc., which are the raw materials for manufacturing zirconosilicate. There is no problem even if it is mixed in as In addition, it is preferable that these amounts are 10 weight or less of 5 ioz.

Furthermore, the amount of moisture attached to zirconosilicate is 25°C and 70°C.
The refraction of the zirconosilicate used in the present invention, which can be reduced to 20% or less under SBR, is $1.40-1.47,
Specific surface area is 800 m”/, li+ or less, specific gravity is 1.9
~2.3, and those with a liquid absorption amount of 0.4 to 2.0 go/9 are preferred.

Nine, the zirconosilicate has an average particle diameter of 0.5 μm or less as measured by the SEM method, and an average particle diameter of 1 to 30 μm, particularly 2 to 20 μm, as measured by the sedimentation method.
Preferably.

The amount of zirconosilicate added to the dentifrice composition is preferably 1 to 50 inches (wt%, same hereinafter), particularly preferably 5 to 30 inches, based on the total composition.

The above-mentioned solconosilicate can be obtained, for example, by reacting a mineral acid containing a zirconium salt with an alkali metal salt of silicic acid. As the alkali metal salt of silicic acid, silicates of sodium, potassium, and lithium can be mentioned, but IJum silicate is generally used because it is relatively inexpensive.

In addition, as an alkali metal salt of silicic acid, its molar ratio (5
102/X20 (X represents an alkali metal)
) can be used. As acidifying agents for these alkali metal silicate salts, mineral acids 1 such as hydrochloric acid,
Sulfuric acid, nitric acid, etc. are used. When producing zirconosilicate by total reaction of the alkali metal salt of silicic acid and mineral acid, it is necessary to add a zirconium salt. Examples of zirconium salts include water-soluble zirconium salts, such as zirconyl chloride (Zr0Ct2), zirconyl sulfate,
Zirconyl acetate and the like are preferably used. Here, the zirconium salt is pre-mineralized! It is most preferable to add the silicic acid to the silicic acid and react with the alkali metal salt of silicic acid.

When the above production method is adopted, it is possible to produce zirconosilicates with different polishing forces and liquid absorption amounts depending on the amount of zirconium bonding, and therefore it is easy to adjust the polishing force and liquid absorption per unit, making it very effective. It's a method.

In addition to zirconosilicate, the present invention includes ordinary amorphous silicic anhydride, aluminosilicate, dicalcium phosphate dihydrate, dicalcium phosphate anhydrate, calcium carbonate, insoluble sodium metaphosphate, and hydroxide. Abrasives such as aluminum, aluminum, polymethyl methacrylate, crystalline zirconia-containing silicates, titanium dioxide, and other polishing agents can be blended. In this case, when obtaining a transparent dentifrice composition using solconosilicate, abrasives such as amorphous silicic anhydride or aluminosilicate that are usually used in the production of transparent dentifrices, abrasives that tend to reduce transparency, and gloss. There is no problem with adding agents, but the amount of abrasives and brighteners that reduce transparency should be 10% of the total composition.
less than or equal to 1, preferably 1 to zirconosilicate
It is preferable that the amount is less than 0.

The dentifrice composition of the present invention includes water in the zirconosilicate,
It is mixed into a dentifrice vehicle containing a binder and a surfactant.

In this case, in the present BA, the binders include carrageenan, seaweed extract, cellulose derivatives such as sodium carboxymethylcellulose, alkali metal alginates such as sodium alginate, gums such as xanthan gum, polyvinyl alcohol, carboxyvinyl polymer, /IJt' Synthetic binder such as nylpyrrolidone, r
One or more inorganic binders such as amorphous silicic anhydride, pea gum [F], kaolin, bentonite, etc. can usually be blended in 0.02 to 5 g of the total toothpaste composition. In particular, we provide sodium carboxymethylcellulose, carrageenan, and carboquine vinyl poly toothpaste compositions.

Here, carboxymethylcellulose sodium (CM
C-N! L) is preferably one with a high degree of etherification (D, S,) of 1°1 or more. By using this type of CMC-Na, it is possible to achieve good dispersibility and improve skin care. You can get a good toothpaste.

In this case, CMC-Na with a high degree of etherification can be preferably used if the viscosity of a 1 m aqueous solution (BH type viscometer, 25°C) is 200 centipoise or less, and the amount of the compounded amount is 0.
．． It is more preferable to set it to 5 to 2 inches.

In addition, CMC-Na has a low polymerization degree from the viewpoint of toothpaste dispersibility and stringinability, especially one with a viscosity of 100% aqueous solution (B
Viscosities with an H-type viscometer (at 25° C.) of 1007 inches or less can also be preferably used. In this case, this low polymerization degree CM
The amount of C-Na glue, S, can be 0.5 to 1.5, and the amount thereof is preferably 0.5 to 3 in the entire composition.

Furthermore, examples of carrageenan include l-type carrageenan, type carrageenan, etc. In this case, when monovalent or divalent metal ions are added to carrageenan, it becomes dull, and a toothpaste with good dispersibility and shape retention can be obtained. . In particular, calcium ions are effective for gluing in the case of l-type carrageenan, and potassium ions are effective for gluing in the case of di-type carrageenan, so it is preferable to use salts that provide these metal ions together with carrageenan. Here, the ratio of carrageenan to metal ions is carrageenan 1 to 5.
It is preferable to use 0.1 to 3 parts by weight of metal ions to 0 parts by weight. In addition, it is more preferable that the amount of carrageenan to be blended is 0.3 to 2 g based on the total composition.

Carboxyvinyl polymers include commercially available ones, such as BF Gutsrich Company's Cal 4-
934, 940, 941, etc. can be used, and Rheosic 250H from Nippon Cotton Co., Ltd. is a neutralized salt-type carboxyvinyl polymer.

252L, 835H, etc. can be used, and by using these polymers, #! has good dispersibility and excellent heat retention. You can get fungal polish. In addition, the amount of carboxyvinyl polymer blended is 0.03 to 1.51 of the total composition.
In particular, it is more preferable to set it as 0.2 to 1 rice cake.

In the present invention, an anionic surfactant and/or a nonionic surfactant is further blended, but when a zirconosilicate and an anionic surfactant are combined, excellent foaming properties are exhibited, and the amount of anionic surfactant is Gives good foaming even with a small amount of foam.

Examples of anionic surfactants include soaps, water-soluble salts of higher alkyl sulfates whose alkyl group has 8 to 18 carbon atoms (e.g., sodium lacryl sulfate, sodium myristyl sulfate), α-olefin sulfonates (
For example, sodium a-olefin sulfonate (having 14 carbon atoms), 2-hydroxyalkanesulfonate, dioctyl sulfosucci is a salt, sodium alkyl sulfoacetate, water-soluble salt of higher fatty acid monoglyceride sulfonate (having a fatty acid group having 10 to 18 carbon atoms) ( For example, sodium lauryl monoglyceride sulfonate, sodium coconut monoglyceride sulfonate), higher fatty acid sodium monoglyceride monosulfate, salts of amides of lower aliphatic amino acids and higher fatty acids having 12 to 18 fatty acid carbon atoms (e.g. sodium lauroyl sarcosinate, N -Sodium acylglutamate, N-acyl-N-methyl-β-alanine sodium, N-methyl-
N-acyl taurate, etc.), and these 1
A species or two or more species can be blended.

The blending amount of these anionic surfactants is 0.5% of the total composition.
The amount of anionic surfactant can be 1 to 5%, especially 0.5 to 2%, but as described above, according to the present invention, by using zirconosilicate as the abrasive, the amount of anionic surfactant can be adjusted to at least provide good foaming. Therefore, the amount of anionic surfactant used can be reduced.

Note that among the above-mentioned anionic surfactants, sodium lauryl sulfate and sodium myristyl sulfate can be effectively used.

Furthermore, by combining zirconosilicate with a nonionic surfactant, a smearing composition with excellent shape retention, dispersibility in the mouth, and juice effect can be obtained.

Here, as the nonionic surfactant, fatty acid jetanolamide, stearyl monoglypeptide, whose fatty acid group has 10 to 16 carbon atoms, and sucrose fatty acid ester whose fatty acid group has 12 to 18 carbon atoms (for example, , mono- and dilaurate), lactose fatty acid ester, lactose fatty acid ester, lactitol fatty acid ester, maltitol fatty acid ester, raffinose j fat 2 ester, sorbitan monostearate condensate with about 60 moles of ethylene glycol added, ethylene oxide and propylene Examples include oxide polymers and derivatives thereof (for example, polyoxyethylene polyoxypropylene monolauryl ester), among which sucrose fatty acid ester, lactose fatty acid ester, lactitol fatty acid ester,
Maltitol fatty acid ester, maltotriitol fatty acid ester, maltotetriitol fatty acid ester, maltopentitol fatty acid ester, maltohexitol fatty acid ester, maltoheptitol fatty acid ester, raffinose fatty acid ester is compatible with zirconosilicate is suitable for use. In addition,
The blending amount of these nonionic surfactants is 0.5% of the total composition.
1 to 51, preferably 9.3 to 3.

In this case, the sucrose fatty acid ester preferably has an unreacted fatty acid content of 4% or less.

In addition, lactose fatty acid ester, lactitol fatty acid ester, maltitol fatty acid ester, maltotriitol fatty acid ester, maltotetriitol fatty acid e: x-
Stell, maltopentitol fatty acid ester, maltohexitol fatty acid ester, maltoheptitol fatty acid ester, and raffinose fatty acid ester all have an acyl group with 8 to 20 carbon atoms, especially in the case of a saturated acyl group. In the case of an unsaturated acyl group, those having 16 to 18 carbon atoms are preferable in terms of foamability, taste, etc. Note that the acyl group may be linear or branched. Further, the average degree of esterification is 0, 5 to 3.0,
In particular, it is 0.8 to 2.0, and the monoester content is 601
The above are preferred.

In the present invention, anionic surfactants and nonionic surfactants may be used alone or in combination, but include sucrose fatty acid ester, lactate fatty acid ester, maltitol fatty acid ester, Lyitol fatty acid ester, maltotetriitol fatty acid ester,
When maltopentitol fatty acid ester, maltohexitol fatty acid ester, maltoheptitol fatty acid ester, raffinose fatty acid ester is used, it is combined with N-long chain acylamino acids, especially saturated or unsaturated acyl having 8 to 20 carbon atoms. It is preferable to use an alkali metal salt of N-substituted glutamic acid, sarcosine or N-methyl-β-alanine in combination, as this provides good foaming properties.

In this case, the proportion of nonionic surfactants used in combination is 1 to 1.
1 to 2 N-long chain acylamino acids per 50 parts by weight
The amount of N-long chain acylamino acids is preferably 0.05 to 2 parts by weight based on the total composition.

The tooth brushing vehicle may further contain one of a thickening agent such as glycerin, sorbitol, polyethylene glycol having an average molecular weight of 200 to 6,000, ethylene glycol, propylene glycol, reduced starch saccharide, xylitol, etc., if necessary.
A species or two or more species can be blended. The blending amount of these thickeners is usually 10 to 80% of the total composition, preferably 30 to 6% (
11.

In addition, the vehicle may contain flavoring agents such as 4) essential oils such as mother mint and sour mint, and flavor materials such as t-menthol, carmen, oidanol, and anethole, either singly or in combination (the amount usually 0.1 of the total composition
~5%, preferably 0.5-2%). Furthermore, sweeteners such as saccharin sodium, aspartame, stevioside, neohesperi sol dihydrochalcone, glycyrrhizin, perillartine, and p-methoxycinnamic aldehyde may be blended alone or in combination (the blending amount is usually 0.01 of the total composition). ~5L, preferably 0.0
5-2ch).

Furthermore, preservatives such as sodium dihydroacetate, p-hydroxymethylbenzoic acid, p-hydroxybutylbenzoic acid, and sodium benzoate, crystalline cellulose powder such as Avicel II, gelatin, and other ingredients may be blended. Furthermore, the dentifrice vehicle contains active ingredients such as enzymes such as debasetranase, amylase, protease, mutanase, phosphatase, lysozyme, and ritequendime, and alkali metal monomers such as sodium monofluorophosphate and potassium monofluorophosphate. Fluorophosphate, sodium fluoride, fluoride 1
．． Fluorocarbon compounds such as III, stannous pyrophosphate, etc.
Tin compounds, chlorhexidine salts such as chlorhexidine hydrochloride and chlorhexidine gluconate, copper chlorophyllin sodium, hinokitiol, epsilon aminocaproic acid, tranexamic acid, ethanedihydroxydiphosphonate, allantoin chlorhydroxyaluminum, nohydrocholesterol, glycyrrhetinic acid, azulene, Herbal medicines such as chamomile, chelating phosphate compounds such as chlorophyll and glycerophosphate, sodium chloride, aqueous inorganic phosphate compounds, etc.
The species or species may be combined in effective amounts.

When preparing a dentifrice composition, can zirconosilicate be mixed with other ingredients? However, a transparent dentifrice composition can be obtained by making the vehicle transparent and adjusting the refractive index to be substantially the same as that of the zirconosilicate.

In this case, it is preferable to add a water-soluble salt to the transparent toothpaste, and the transparency can be further improved by adding a water-bathable salt.

Here, the water-bathable salt is preferably an alkali metal salt or an alkaline earth metal salt, and particularly one having a solubility in water at 20°C of 1 g or more, and more preferably a molecular weight of 20°C.
It is less than or equal to 0. Specifically, water-soluble salts include barium acetate, barium chloride, barium nitrate, calcium acetate, calcium chloride, calcium nitrate, potassium acetate,
Potassium chloride, potassium phosphorus, potassium hydrogen phosphate,
Potassium sulfate, potassium nitrate, magnesium chloride, magnesium sulfate, sodium acetate, sodium carbonate, sodium chloride, sodium phosphate, sodium hydrogen phosphate, sodium nitrate, sodium sulfate, sodium fluoride, sodium monofluorophosphate, etc. One or more of these may be added. The amount of these water-soluble salts added is 0.1 to 10%, particularly 0.1 to 5% of the total composition.
Preferably left.

Effects of the Invention The polishing composition of the present invention is pleasant to use, and when made of transparent KN, has high transparency.

Next, O showing production examples of zirconosilicates of the present invention [Production Examples] Sulzorconosilicates having various amounts of zirconium bonding were obtained by the following method.

Method for producing zirconosilicate A 5 inch 2100 fiAIl was placed in a 20 volume reaction vessel equipped with a stirrer having a 150 mm diameter turbine blade.
, NaC 20.9/kl? Add 10 kg of sodium silicate (Na20.3.1Si02) aqueous solution containing
The reaction temperature was maintained at 87°C, and 3688# of 10-thiosulfuric acid containing zirconyl chloride at various concentrations was added at a flow rate of 369/min. Next, 10-thiosulfuric acid was added at a flow rate of 8397 ml, and when the reaction system temperature reached 2.8, the addition of acid was stopped and the mixture was aged for 15 minutes. Next, filtration and water washing were repeated, and the mixture was kept at 100° C. and dried in a dryer, followed by finely pulverizing to obtain zirconosilicates having various amounts of zirconium bonds.

Examples and comparative examples are shown below.

The properties of the zirconosilicate used in the following examples are shown in Table 1.

Table 1 A toothpaste composition having the following composition was prepared.

[Example 1] - Zorconosilicate A 20 ts Propylene glycol 3.0 Sodium carboxymethyl cellulose 1.1 (D,
S, 1.2.1% viscosity 150 cm) Glycerin 1060% Nlupit
15 Chlorhexidine hydrochloride 50 pp
mFragrance 1.0 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Lauroyl diethanolamide 0.5 Water
Residue [Example 2] Zirconosilicate B 15 Ticalgeximethylcellulose sodium 1.
5 (D, S, 0.9.1 viscosity 20 centipoise) 60
%Nrubit 40 Polyethylene Glycol 400 5.0 Fragrance
1.0 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Lauroyl diethanolamide 0.5 [Example 3] Zirconosilicate C25 ciderobylene glycol 3. Ot type carrageenan 1.0 calcium chloride
0.15 glycerin
56Cl nrubitsuto
35 Sodium monofluorophosphate
0.76 Flavor 1.9 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Lauroyl diethanolamide 0.5 Water

Residue [Example 4] Solconosilicate A 30 Thipropylene glycol 3.0 Type carrageenan 0.8 (Contains 1096 L type carrageenan) Potassium chloride
0.160%60% sorbitol
45 Tranexamic acid 0.05 Flavor 1.0 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Lauroyl diethanolamide 0.5 Titanium oxide 0.05100.0% [Example 5] Zirconosilicate B 25 Thipropylene glycol 3 .0 Carboxyvinyl Polymer 015 (Carbopol 940) Sodium Hydroxide 0.26 Glycerin 560 Chinlupit
35 Dextranase (200,000 units/, 9) 1.0 Flavor
1.0 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Lauroyl diethanolamide 0.5 Water
Remainder [Example 6] Zirconosilicate) C10 tactical vinyl polymer 0.9
(Leonoc 250H) Glycerin 2060 Thisolbit 15 Polyethylene Glycol 4
00 5.0 Fragrance 1.
0 Sodium lauryl sulfate 1.5 Sodium saccharin 0.1 Lauroyl diethanolamide 0.5 Water
Residue [Comparative Example 1] Calcium carbonate 50% Propylene glycol 3.0% Sodium methyl cellulose 1.2 (D, S, 0
．． 9.1% viscosity 120 centipoise) 60% sorbitol 20 fragrance 1.0 sodium lauryl sulfate 1.5 saccharin sodium 0.1100.
Next, the toothpastes of Examples 1 to 6 and Comparative Example 1 were evaluated for their dispersibility in the mouth, skin condition when extruded from the tube, shape retention, and stringiness. The results are shown in Table 2. The evaluation method and evaluation criteria are as follows.

Dispersibility in the mouth The toothpaste was evaluated by actually using it.

◎: Spreads in the roller very quickly.

It must spread quickly within 2 days.

Δ: Slightly poor spread during the day, slightly sticky.

×: It does not spread in the mouth and has a sticky feel.

Skin condition A tube was filled with toothpaste, extruded onto paper, and the skin condition was sensory evaluated.

◎: Very smooth and beautiful skin.

○: Smooth and beautiful skin.

Δ: There is a little lameness, but the product value is good.

X: The skin is dull and the commercial value is poor.

Toothpaste was filled into a tube, extruded onto a toothbrush, and the state at that time was sensory evaluated.

Shape retention ○: Goes well on the toothbrush.

Δ: Slightly flows on the toothbrush, but has commercial value.

×: The toothbrush runs down.

Threadability ○: Good consistency and easy to apply on toothbrush.

Δ: There is a slight amount of kneading, but the product is worth it.

X: Poor adhesion, strong stringiness, and difficult to put on a toothbrush.

According to the results shown in Table 2, it was found that the use of zirconosilicate in combination with sodium carboxymethylcellulose, carrageenan, and caldexyvinyl I reamer improved the dispersibility in the mouth.

Examples 7-10. Comparative examples 2 to 5 A kneading composition having the following composition was prepared.

[Example 7] Zirconosilicate A 25 Thickening Silica 2.0 Propylene Glycol 2.060 Thin Lupit
50 Sodium carboxymethyl cellulose 1.2 Sodium saccharin
0.1 Fragrance 1.0 Sodium lauryl sulfate 1.22
Uroylsarcosine sodium 0.3
[Example 8] Zirconosilicate B 25% Thickening Silica 2.0 Propylene Glycol 2.060 Tin Lupit
50 Sodium calcylmethyl cellulose 1.2 Sodium saccharin
0.1 Fragrance 1.0 Sodium lauryl sulfate 0.7 Sodium lauroyl sarcosinate 0.3 [
Example 9] Zirconosilicate C10 thickening silica 3.0 Propylene glycol 2.060 Chinlupit 65 Cal? Sodium oxymethylcellulose 1.1 Sodium saccharin
0.1 Fragrance 1.0 Sodium lauryl sulfate 0.7 Sodium lauroyl sarcosinate 0.3 Water
Remaining 100, O% [Example 10] Solconosilicate) A 10 thickening silica 3.0 Propylene glycol 2.060% Sorbit
65 Cal? Sodium oxymethylcellulose 1.1 Sodium saccharin
0.1 Fragrance 1.0 Sodium lauryl sulfate 0.7 Water
Remaining [Comparative Example 2] Calcium hydrogen phosphate dihydrate 45 Thickening silica 2.0 Propylene glycol 2.060 Chinlupit 30 Sodium carboxymethyl cellulose 1.2 Sodium saccharin 0.1 Flavor 1.0 Sodium lauryl sulfate 1 .2 Sodium lauroyl sarcosinate 0.3 Water
Remaining [Comparative Example 3] Calcium hydrogen phosphate dihydrate 45 Thickening silica 2,0 Propylene glycol 2.060 Chinlupit 30 Sodium calgeximethylcellulose 1.2 Sodium saccharin
0.1 Fragrance 1.0 Sodium lauryl sulfate 0.7 Sodium lauroyl sarcosinate 0.31
00.0% [Comparative Example 4] Calcium carbonate 45% Silica 2.0 Propylene glycol 2.060% Sorbitol
30 Sodium calgeximethyl cellulose 1.2 Sodium saccharin
0.1 Fragrance 1.0 Sodium lauryl sulfate 1.5 Sodium lauroyl sarcosine 0.3 [
Comparative Example 5] Calcium carbonate 45% thickening silica 2.0 Glopylene glycol 2.060 Tinlupit
30 Cal? Sodium oxymethylcellulose 1,2 Sodium saccharin
0.1 Flavor 1.0 Sodium lauryl sulfate 1.0 Sodium lauroyl sarcosine 0.3 Next, Examples 7 to 10. The toothpastes of Comparative Examples 2 to 5 were actually used, and their foaming was sensory evaluated by a panel of 10 experts. The results are shown in Table 3. Note that the foaming evaluation criteria are as follows, and the results are the average of the scores of 10 No9nels.

4: Good foaming.

3: Good foaming.

2: Slightly poor foaming.

1: Poor foaming.

According to the results shown in Table 3, it was found that when zirconosilicate was used as an abrasive, the amount of anionic surfactant blended at least gave good foaming.

Examples 11-20 A toothpaste composition having the composition shown in Table 4 was prepared.

All of these dental formulas show good lathering.

Examples 21-23. Comparative examples 6-7 A toothpaste composition having the following composition was prepared.

[Example 21] Zirconosilicate) A 25% 60%
Solvit 40 Cal? Sodium oxymethylcellulose 1.0 sucrose mono/
J? Lumitate 2.0 fragrance
1.0 Sodium saccharin 0.1 Water

Remainder [Example 22] Zirconosilicate B 25% 60 Manlupit 40 Sodium carboxymethylcellulose 1.0 Sucrose monomyristate 1.5 Sodium N-lauroylglutamate
0.5 Flavoring 1.0 Saccharin Sodium 0.1 Water
Remaining [Example 23] Zorconosilicate C25 Tyroq6 Rubit 40 Sodium carboxymethyl cellulose 1.0 Sucrose monolaurate 1.5 Sodium lauryl sulfate 0.3 Flavor 1.0 Sodium saccharin 0.1 Water
Remaining [Comparative Example 6] Sodium hydrogen phosphate dihydrate 50 Chiro 0Ls Sorbitto 20 Cal? Sodium oxymethylcellulose 1.0 Sodium lauryl sulfate 1.5 Flavoring 1.0 Sodium saccharin 0.1 Water

Residue [Comparative Example 7] Sodium hydrogen phosphate dihydrate 50
160ts sorbitol 20calcexymethylcellulose sodium 1.2sodium lauryl sulfate 1.5flavoring 1.0sodium saccharin 0.1water
Next, the viscosity, shape retention, dispersibility in the mouth, and juice effect of the toothpastes of Examples 21 to 23 and Comparative Examples 6 and 7 were evaluated. The results are shown in Table 5. The viscosity is the result of measurement using a BH type viscometer at 25°C, and the evaluation method and evaluation criteria for shape retention and mouth dispersibility are the same as the evaluation methods and evaluation criteria described above. Evaluation method and evaluation criteria are as follows)
It is.

After brushing their teeth with the toothpastes of Examples and Comparative Examples, they immediately drank the juice and sensory-evaluated its taste.

O Niji Youth is delicious.

It tastes like Δ rainbow youth.

×No rainbow taste at all◎ According to the results shown in Table 5, it was confirmed that the use of zirconosilicate in combination with a nonionic surfactant improved shape retention, dispersibility in the mouth, and juice effect. .

Example 24 A transparent toothpaste composition having the following composition was prepared.

Zirconosilicate C10% Thickening Silica 2.5 Polyethylene Glycol 400 5.0 Sodium Caldexymethyl Cellulose 1.0
99.5 Tiglycerin 21.470%
Sorvit 42.6 Sodium lauryl sulfate 1.2 Sodium saccharin 0.1 Sodium chloride
1.0 fragrance 1.0 water
Next, the turbidity of this transparent toothpaste was measured at 25° C. using an integrating sphere turbidimeter based on the transmittance at a sample thickness of 1 inch. The result was 0.09.

Note that the turbidity of a transparent toothpaste having the same composition as above except that no sodium chloride was added was 0.15.

Therefore, it has been recognized that transparency can be improved by adding a water-soluble salt (sodium chloride) to zirconosilicate.

A transparent toothpaste composition having the following composition was prepared by adding the water-soluble salt shown in Table 6.

Zirconosilicate 0 20% thickening silica 2.596q6 glycerin 18.070 tin rubit
38.5 polyethylene glycol 400
5.0 Sodium carboxymethyl cellulose 1.1 Sodium lauryl sulfate
1.2 Satucalin Sodium
0.1 Fragrance 1.0 Water-soluble salt 1.0 Water
The turbidity of each transparent #i toothpaste was measured in the same manner as in Example 24 during the remaining flames. The results are shown in Table 6.

Table 6 Note that the turbidity of a transparent toothpaste having the same composition as above except that no water-soluble salt was added was 0.24.

Therefore, it was confirmed that transparency can be improved by adding water and a soluble salt to zirconosilicate.

A transparent toothpaste composition having the following composition was prepared.

[Example 30] Zirconosilicate) A 10 thickening silica 3.0 polyethylene glycol 400 5.099.5
Tiglycerin 2'3.470% sorbitol 46.8 Sodium carboxymethyl cellulose 1.0 Sodium lauryl sulfate 1.2 Sodium saccharin 0.1 Fragrance 1.0 KCII 1.0 Red No. 2 0.0005100
．． 0 [Run 31] Zirconosilicate A 15% Thickening Silica 2.5 Preethylene Glycol 400 5.099.
5% glycerin 21,470% sorbitol 44.3 Sodium sulfate methyl cellulose 1.0 Sodium lauryl sulfate 1.2 Sodium saccharin 0.1 Flavor 1
．． 0 KH2PO40,5 Na2HPO40,5 Red No. 3 0.001 [Example 32] Zirconosilicate A 25 Thi thickening silica 1.0 Polyethylene glycol 400 5.099.5q6
Glycerin 18.970 tin rubit
38.8 Sodium carboxymethyl cellulose 1.0 Sodium lauryl sulfate 1.2 Sodium saccharin 0.1 Fragrance 1.0 NaC2H302.3H201.0 Red No. 106 0.001 [Example 33] Zirconosilicate) 0 10% thickening silica 3 .0 Polyethylene glycol 400 5.099°596
Glycerin 20.270% Sorbitol 40.4 Sodium carboxymethyl cellulose 1.0 Sodium lauryl sulfate 1.2 Sodium saccharin 0.1 Flavor 1.0 Na2P03F 0.76 Yellow No. 4
o, oos [Example 34] Zirconosilicate) C15 Thickening Silica 2.5 Polyethylene Glycol 400 5.070 Tin Rubit 57.0 Cal? Sodium oxymethylcellulose 1.0 Sodium lauryl sulfate 1.2 Sodium saccharin 0.1 Flavoring
1.0 NaC15.0 Blue No. 1 0.001100
．． 0 [Example 35] Zirconosilicate) B 25% polyethylene glycol 400 5.099,
5% Glycerin 20.270' Tinrubito 31.0 Sodium carboxymethyl cellulose 1.0 Sodium lauryl sulfate 1.2 Sodium saccharin 0.1 Flavor
1.0 NaCj' 2.0 Red No. 3 0.0005 Yellow 4
No. 0.005 [Example 36
] Zirconosilicate B 10% thickening silica 2.5 Polyethylene glycol 400 5.099.5
% Glycerin 30.4 70 Tin Rubit 45.6 Sodium carboxymethylcellulose 1.0 Sodium lauryl sulfate 1.2 Sodium saccharin 0.1 Flavor
i.

BaCJ2 1.0 Yellow No. 4 o, o o s Blue No. 1 0.001 Water
Residual
Example 37] Zirconosilicate) B 15% thickening silica 2.04 Liethylene glycol 400 5.099.5 Tiglycerin 30.070% Sorbit
40.6 Caldexymethylcellulose Nato IJ Rum 1.0 Sodium lauryl sulfate 1.2 Sodium saccharin 0.1 Flavor 1.0 NaC2H302・3H20' 1.0 Acid Dred 0.001 Water
Residue [Example 38] Zirconosilicate B 25 Thickening Silica i.

I diethylene glycol 400 5.
099.5 Tiglycerin 30.570T
Bit on o7 31. .

Carboxymethyl cellulose sodium 1
．． 0 Sodium lauryl sulfate 1
．． 2 Saccharin Sodium 0.1 Flavor 1゜0 CaC12・6H20 1.0 Red No. 2 0.001 Yellow 4
No. 0.001 water
100 left.
0% All of the transparent toothpastes of Examples 30 to 38 were highly transparent compared to those containing no water-soluble salts, giving them a score of 6.9.

Claims (1)

[Claims] 1. In a dentifrice composition containing a binder and a surfactant, a synthetic amorphous zirconium bond with a zirconium bond amount of 0.1 to 10% by weight based on SiO_2 calculated as ZrO_2 as an abrasive. A toothpaste composition characterized by containing a silicate. 2. The amount of zirconium bonded in the synthetic amorphous zirconium-bonded silicate is 0.2 to SiO_2 as ZrO_2
The dentifrice composition according to claim 1, wherein the content is in the range of 2% by weight. 3. The dentifrice composition according to claim 1 or 2, wherein the synthetic amorphous zirconium-bonded silicate and the dentifrice vehicle are made transparent by having substantially the same refractive index. 4. The dentifrice composition according to any one of claims 1 to 3, wherein the amount of the synthetic amorphous zirconium-bonded silicate is 1 to 50% by weight of the composition. 5. The refractive index of the synthetic amorphous zirconium-bonded silicate is 1.
40-1.47, specific surface area 800m^2/g or less, specific gravity 1.9-2.3, liquid absorption amount 0.4-2.0ml/g
A dentifrice composition according to any one of claims 1 to 4. 6. The dentifrice composition according to any one of claims 1 to 5, wherein the binder is carboxymethyl cellulose sodium. 7. The dentifrice composition according to claim 6, wherein the degree of etherification of sodium carboxymethyl cellulose is 1.1 or more. 8. The dentifrice composition according to claim 6, wherein the viscosity of the 1% aqueous solution of sodium carboxymethyl cellulose is 100 centipoise or less. 9. The dentifrice composition according to any one of claims 1 to 5, wherein the binder is carrageenan. 10. The dentifrice composition according to claim 9, wherein the carrageenan is ι type carrageenan, and calcium ions are used in combination with the carrageenan. 11. The dentifrice composition according to claim 9, wherein the carrageenan is κ type carrageenan, and potassium ions are used in combination with the carrageenan. 12. The dentifrice composition according to any one of claims 1 to 5, wherein the binder is a carboxyvinyl polymer. 13. The dentifrice composition according to any one of claims 1 to 12, wherein the surfactant is an anionic surfactant. 14. The dentifrice composition according to any one of claims 1 to 12, wherein the surfactant is a nonionic surfactant. 15. The nonionic surfactant is sucrose fatty acid ester, lactose fatty acid ester, lactitol fatty acid ester, maltitol fatty acid ester, maltotriitol fatty acid ester, maltotetriitol fatty acid ester, maltopentitol fatty acid ester, maltohexitol fatty acid ester One or two selected from ester, maltoheptitol fatty acid ester, and raffinose fatty acid ester
15. The dentifrice composition according to claim 14, which contains at least one species. 16. The dentifrice composition according to claim 14 or 15, in which a nonionic surfactant is used in combination with an N-long chain acylamino acid. 17. In a dentifrice composition containing a binder and a surfactant, a synthetic amorphous zirconium-bonded silicate having a zirconium bond amount of 0.1 to 10% by weight based on SiO_2 in terms of ZrO_2 is blended as an abrasive; A toothpaste composition characterized by containing a water-soluble salt. 18. The amount of zirconium bonded in the synthetic amorphous zirconium-bonded silicate is 0.2 as ZrO_2 with respect to SiO_2.
18. The dentifrice composition of claim 17 in the range of 2% by weight. 19. The dentifrice composition according to claim 17 or 18, which is made transparent by making the synthetic amorphous zirconium-bonded silicate and the dentifrice vehicle have substantially the same refractive index. 20. The dentifrice composition according to any one of claims 17 to 19, wherein the amount of the synthetic amorphous zirconium-bonded silicate is 1 to 50% by weight of the composition. 21. The refractive index of the synthetic amorphous zirconium-bonded silicate is 1.
．． 40 to 1.47, specific surface area 800 m^2/g or less,
Specific gravity is 1.9-2.3, liquid absorption amount is 0.4-2.0ml/
The dentifrice composition according to any one of claims 17 to 20, which is g. 22. The dentifrice composition according to any one of claims 17 to 21, wherein the water-soluble salt is an alkali metal salt or an alkaline earth metal salt. 23. The solubility of water-soluble salt in water at 20°C is 1
23. The dentifrice composition according to claim 22, wherein the dentifrice composition is one or more. 24. The dentifrice composition according to claim 23, wherein the water-soluble salt has a molecular weight of 200 or less.