JPS61172065A - Automatic chemical analyser - Google Patents

Abstract

PURPOSE:To enhance the efficiency of analytical measurement, by driving an one-channel dilution line having diluent reaction tubes arranged thereto and plural-channel analytical lines having analytical reaction tubes respectively arranged thereto in a cooperated state. CONSTITUTION:An one-channel dilution line 1a is used in the dilution of specimens and diluent reaction tubes Ta (T11-Tm1) having dilute specimens received therein are arranged to said dilution line 1a while plural-channel analyti cal lines 1b have analytical reaction tubes Tb (T12-T1n+1, T22-T2n+1...Tm2-Tmn+1), which receive reaction solutions and are subjected to predetermined analytical measurement, arranged thereto. The dilution line 1a and the analytical lines 1b are driven by a drive means in a cooperated state and the diluted specimens in the diluent reaction tubes Ta of the dilution line 1a are distributed to the corresponding analytical reaction tubes Tb of the analytical lines 1b by a distribution means. By this method, the distribution position of the diluted specimens to the analytical lines 1b receives no limit and the distribution of the diluted specimens can be performed in a required number at a required position.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an automatic chemical analyzer that fully automatically analyzes multiple items on multiple samples.

In this type of automatic chemical analyzer, one of the extremely rational methods when trying to perform multiple analyzes in a short time to increase analysis efficiency is to use multiple reaction lines to simultaneously analyze samples. There is a method to analyze multiple items in parallel. In this case, the operation of dispensing the sample into the reaction vessels of each reaction line is the operation that requires the most time and accuracy. A method in which a single nozzle sucks up a fixed amount of sample from a sampler and discharges it into a reaction vessel repeatedly for each reaction line. This includes methods for sucking up and discharging a fixed amount into the reaction vessels of each reaction line. However, all of these methods suffer from inefficiency, which is the biggest obstacle to improving the number of analysis items of multi-item automatic chemical analyzers and the number of samples analyzed per unit time.

The present invention was made based on these circumstances, and
The purpose of the present invention is to provide an automated chemical analysis device that can perform multi-item analysis of a large number of samples with high efficiency.

That is, the present invention is characterized in that the number of reaction tubes is arranged in a line in a first direction to form 11 reaction tube rows, and the reaction tube rows are arranged in a second direction intersecting the first direction. Dispensing the sample solution prepared in the sampler into the reaction tubes prepared in the sampler while moving the reaction lines arranged in multiple rows step by step with respect to the dispensing means along the second direction. Then, in an automatic chemical analyzer that performs scheduled measurement and analysis on each of these dispensed reaction tubes and performs multi-channel automatic analysis, each reaction tube array is divided into analysis reaction tubes of each channel and dilution reaction tubes. Increased number of analysis channels by 1
The reaction line consists of only a few reaction tubes, and in response to the step operation of this reaction line, the sample solution is sequentially sucked up from the sump and discharged into the dilution reaction tube of the 11th reaction tube row, and further diluted into the reaction tube. A 10th dispensing mechanism that injects liquid to dilute the M sample solution, and a first dispensing mechanism that is installed after this first dispensing mechanism and injects the liquid in the dilution reaction tube diluted with paulownia. and a second dispensing wax load that simultaneously sucks up a plurality of rows of wax and simultaneously dispenses the plurality of rows of wax into the analysis reaction tube.

One aspect of the invention will now be described with reference to -Ilait-.

In Figures 1 and 2, 1 is a reed in the reaction line;
n+1 for this reaction line 1 μ analysis channel
For example, a large number of reaction tubes (mil!) in the direction orthogonal to the reaction tube row, i.
,) are arranged to form an endless (endless loop) chain conveyor. This reaction line 1
In, the reaction tube row "l z" 2 m...Lm are reaction tubes T, □~T zn+x, Tns-T*, respectively.
n+1. -, Tms~Ta+n+x, each reaction tube Tl 1-Tx n+x.

? ! 1~T wealth n+1. -Is TmlyTtarh+1 a reaction tube for dilution? ■* Tm 1. -, Ta+ s and analytical reaction tubes Tll to Tin+1. T22~T*n,,+s
, ・=T+as〜Ta+! It is differentiated into l+1. And the reaction line 1 with is the reaction tube array Lll L2
It is driven intermittently in the direction of arrow M in the figure at a pitch corresponding to rA 4 of #.... 2 is the 10th pipetting machine groove, and this first pipetting @42 is carried out by the pump device 1t21, which sucks the sample Wf through the nozzle 22 from the syssembler S, and supplies it to the reaction line 1 for dilution. A series of operations t in which the reaction tube T1□T21... is discharged, and then a diluting solution such as physiological saline is injected and diluted, and then washed in the washing tank P - the opening in the reaction line 1 I will do it again and again at the end of the fifth year. The sampler S is composed of a container containing a sample liquid, and is appropriately driven so that the container containing the sample liquid to be analyzed next is successively positioned at the suction position by the first dispenser 41.

3 is a second dispensing @ mechanism, and this second dispensing machine ia3 has suction and discharge systems that are out of alignment with each other, and in this case two pipes arranged along the moving direction M of the reaction line 1. Nozzle 31
．． 32f offset, one unit of operation corresponds to two steps of operation for suction and discharge through these nozzles 31.32t, respectively, and in the first step, the cleaning liquid w6 is used in the cleaning tank P and the nozzles 31.32f are After washing, inhale the contents of the two dilution reaction tubes Tl1wT21...
In the second step, two rows of analytical reaction tubes T1
Discharge and inject at 2~Tt a+t and Tm +1/-, respectively. 4 and 5 are reaction tubes for analysis T1m-%
-Tl a+l.

Tm5--Txn+s... is a nozzle for injecting the reagent into the required one according to the analysis item, method, etc., 6 is the reaction tube for analysis Tth~Ttn=l, ? 224T 1
Contents of n 1 t, -. - This is a nozzle for sucking up and sending it into the analyzer when it is in the j direction. Further, 7 is filled with a heat medium liquid such as water, and the reaction tube T> 1-TL n+
1. Tsl~Tl! L+1. . . . All of the sample liquid etc. contained therein are immersed in a constant temperature bath to maintain the temperature of the sample liquid etc. in the reaction tube at a constant temperature. 8 is reaction tube T
11~Tl (1+l, Ts t ~Tx a+1.
- This cleaning processing section 8 includes a first cleaning nozzle 81 for spouting city water. A second cleaning nozzle 82 that spouts pure water. It consists of hot air for drying (t), drying air (hot air), dal 83, etc.

Next, the operation in such collection will be explained.

Reaction line l is reaction tube array "1* lI21...L+s
K12I is performed intermittently, for example, by 1 step every 1 second, with an interval of 1 pitch.

Now, suppose that the reaction tube array corresponds to the operating position of the first dispensing mechanism 2 after moving one step as shown in Fig. 3(a), then the operation of the second dispensing mechanism 3 will change. Position u+, 'Ax
(corresponding to the devices with nozzles 31 and 32, respectively) were equipped with a row of reaction tubes L.

L- corresponds to each 6. In this state, the 10th dispensing structure 2 sucks up a predetermined amount of sample liquid from the sampler S, discharges and injects it into the dilution reaction tube Tll of the reaction tube row 2, and then injects a predetermined amount of diluent Dt into the reaction tube T;1. Dilute by stirring with a sill jet according to the injection force of the injection. At this time, the front row is in the operating position ■2 corresponding to the nozzle 32 of the second dispensing mechanism 3! The dilution reaction tubes Ta+t , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , steps, Which, Which Was Which Were Which The reagent liquid Was injected and diluted in the same manner as described above Was injected and diluted in the operation 1 step before) Was accommodated in the diluent reaction tubes Ta+t. After the tenth dispensing mechanism 2 performs the above-mentioned injection dilution, the nozzle 22 and the like are cleaned in the cleaning tank P during the next step movement and until the reaction line 1 is stopped. (The operation of the second dispensing mechanism 3 during this time will be clarified later, so the explanation will be omitted here.)Next, when the reaction line 1 moves one step, as shown in Fig. 3 (to). The reaction tube row L2 corresponds to the operating position of the tenth dispenser barrel 2. In this state, the 10th dispensing pipe 1 and 2 are the same as described above. At the production position MI [t-ll5, there are reaction tube rows L am and L
1 corresponds to each. And the 10th dispensing Sakura structure 2
While performing the above-mentioned operation, the 20th dispensing mechanism 3 cleans the nozzles 31, 32, etc. using the cleaning liquid W and the cleaning liquid P, and then transfers the reaction tube array located at the operation position II s to II z. L s * IJ l dilution reaction tube T-h e
The contents of T l 1 are sucked up separately through nozzles 31 and 32, respectively.

'Furthermore, if reaction line 1 is transferred by one step, Figure 3 (
As shown in C), the reaction tubes are arranged in the recommended working position of the first dispensing mechanism 2, and the operating position of the 20th dispensing mechanism 3 is 115-H.
The reaction tube arrays Ill s II2 correspond to z, respectively.

Here, the tenth dispensing mechanism 2 injects and dilutes the sample liquid into the dilution reaction tube Tsz in the same manner as described above. In this case, the 20th dispensing ridge structure 3 transfers the sample solution (diluted) sucked up from the dilution reaction tubes TIILL and TLI in the immediately preceding step and step through the nozzles 31 and 32 to the reaction tube row L8m. ``20 analysis fan reaction tube T12s Tzg;
T1! ,'r,3;・++: ””÷s, Tin
Then, the contents of one dilution reaction tube will be dispensed into the analysis reaction tube of the reaction tube row shifted by one row.

Analytical reaction tube T1 where dispensing was carried out in this way! ~TL
! The sample liquid in L, T22~Tam... is injected with a reagent at a location corresponding to the required reaction time for the relevant analysis item by nozzle 4. Each item is sent to the analyzer separately.
Each item is analyzed using an analysis system. The empty reaction tube is placed in the cleaning processing section 8 and is passed through cleaning nozzles 81 and 112.
Processes such as cleaning and drying are performed by the drying nozzle 83 and the like. It should be noted that the reaction tube moving at least from the operating position of the 10th dispensing mechanism 2 to the 6th position of the nozzle is immersed in a constant temperature bath 7 and is constant temperature controlled to a predetermined temperature.

In this way, the transfer period for even one pitch can be made very short with multiple channels, and the speed is extremely high and nine aliquots can be made, which speeds up the analysis time and per unit time. It becomes possible to increase the number of analysis items and samples.

In addition, in the above, a series of operations such as sucking in and dispensing the sample liquid in the first dispensing mechanism 2'' and cleaning the diluted nozzle, or suctioning the diluted sample liquid in the 20th dispensing mechanism 3, cleaning the nozzle, etc. If the time required for the operation is longer than the time required for the injection operation into the multi-channel analytical reaction tubes in the second dispensing mechanism 3, four reaction tube rows for simultaneous five-dispensing may be added accordingly. If the injection operation of the φ channel into the reaction tube for analysis by the second branch m' is extremely long, increase the number of reaction tubes to be pipetted at the same time and reduce the total number of the injection operations. This may be done for each step, and the stopping time of only that step may be increased.In addition, the present invention can be implemented with various modifications within the scope of the invention.

As described in detail above, according to the present invention, it is possible to provide a dynamic chemical analyzer that can perform multi-item analysis of a large number of samples with high efficiency.

[Brief explanation of the drawing]

Fig. 1 is a schematic drawing of a thin acid t-system according to an embodiment of the present invention; Figure 3 (a)
-(C) are diagrams for explaining the operation of the same embodiment. l...Reaction line Ll, Ll...Reaction tube row T11~T o+a+1''・Reaction tube Tth*j
2bi...? '+al...Dilution reaction tube Tt s ~
Ts n+z, T* 5-Tx n+1. −・−TOI
x ~ Tmn+t... Analysis reaction tube 2... First dispensing mechanism 3... 20th dispensing station 4.5... Nozzle (for reagent dispensing) 6... Nozzle (analysis 7...Constant temperature, full 8...Cleaning Department Representative Patent Attorney Takehiko Suzue #2rEJ 3rd CEU Procedural Amendment February 21, 1986 Director General of the Patent Office Michibe Uga 1 , Indication of the case Japanese Patent Application No. 60-221319 2, Name of the invention Automatic chemical analyzer 3, Person making the amendment Relationship to the case Patent applicant (307) Toshiba Corporation 4, Agent 1-chome Toranomon, Minato-ku, Tokyo 26-5 No. 17 Mori Building 6,
Target of amendment 7, contents of amendment (1) The entire text of Mei 111 is corrected as shown in the attached sheet. (2) Figure 2 of the drawing is corrected as shown in the attached sheet. Title of the invention Automatic chemical analyzer 2, Claims In an automatic chemical analyzer for automatically measuring and analyzing a plurality of items on a plurality of samples, an automatic chemical analyzer is used for diluting samples and is used for diluting samples. A one-channel dilution line in which dilution reaction tubes containing a sample are arranged, and a multi-channel analysis line in which analysis reaction tubes containing a reaction liquid and used for predetermined measurement and analysis are arranged. , a driving means for driving the dilution line and the analysis line in conjunction with each other, and in connection with the operation of this driving means, the diluted sample in the dilution reaction tube of the dilution line is transferred to the corresponding multiple channels of the analysis line. An automatic chemical analyzer characterized by comprising means for dispensing into an analysis reaction tube. 3. Detailed Description of the Invention and Objectives of the Invention] (Field of Industrial Application) The present invention relates to an automatic chemical analyzer that automatically performs analysis of a plurality of items on a plurality of samples. (Prior Art) In order to improve the analysis efficiency in this type of automatic chemical analyzer, it is sufficient to perform analysis of multiple items in a short time. As an extremely rational system for analyzing multiple items in a short period of time, multiple step-driven reaction lines are installed, and multiple reaction lines are used to analyze multiple items on the same sample in parallel. There is a system to do it. Conventionally, in this type of system, a sample is sucked up from a sampler and discharged in a predetermined amount into a dilution tank at a fixed location, and then a predetermined amount of diluent such as physiological saline is injected into this dilution tank. The diluted sample is diluted, and the diluted sample in the dilution tank is sucked up and discharged in fixed amounts into the analytical reaction tubes of each reaction line, thereby dispensing the diluted sample into the analytical reaction tubes of each reaction line. After that, the diluted sample in the analytical reaction tube of each reaction line was subjected to analysis. For this reason, the positions at which diluted samples are dispensed into the analysis reaction tubes of each reaction line are significantly restricted by the fixed dilution tank. This has been a major factor in reducing the efficiency of analysis and measurement, such as not allowing the reaction line to proceed until the dispensing of the diluted sample and washing of the dispensing system are completed. (Problems to be Solved by the Invention) As described above, in conventional systems, the diluted sample is only dispensed into the analytical reaction tube of each reaction line, or the dilution is performed in a fixed dilution tank. Therefore, the reaction line cannot be advanced until the dispensing of the diluted sample and the cleaning of the dispensing system are completed, which poses a major problem in terms of the efficiency of analysis and measurement. Therefore, an object of the present invention is to improve the efficiency of analysis and measurement by eliminating restrictions on the positions for dispensing diluted samples and making it possible to dispense diluted samples at multiple positions on an analysis line consisting of reaction tubes for analysis. The purpose of the present invention is to provide an automatic chemical analyzer that can perform the following tasks. [Structure of the Invention] (Means for Solving the Problems) In the automatic chemical analyzer according to the present invention, dilution reaction tubes used for diluting a sample and containing the diluted sample are arranged. A channel dilution line, a multi-channel analysis line in which analysis reaction tubes containing a reaction solution and used for predetermined measurement and analysis are arranged, and a system for driving these dilution lines and analysis lines in conjunction with each other. The method further comprises a driving means, and means for dispensing the diluted sample in the dilution reaction tube of the dilution line into the corresponding plurality of analysis reaction tubes of the analysis line in conjunction with the operation of the driving means. It is a feature. (Function) In the present invention described above, since the dilution line is provided in conjunction with the analysis line, the position for dispensing the diluted sample with respect to the analysis line is not restricted, and the diluted sample can be dispensed in the required number and position. be able to. Therefore, efficient analytical measurements can be performed. (Example) Hereinafter, an example of the present invention will be described with reference to the drawings. In FIGS. 1 and 2, 1 is a reaction line,
This reaction line 1 is n+1 for the number of analysis channels n.
An endless chain conveyor is constructed by arranging a large number (m) of reaction tubes (bottomed cylindrical containers) in a direction perpendicular to the reaction tube rows. In this reaction line 1, reaction tube array L2.・・・
・、L. are reaction tubes ■11 to ■1o+1, respectively. ■21~”2
Consisting of n+1'..., T-T, each reaction tube "1"
1~ll n+n+1 ”In+1□ T21~”2n+1' ”” '
11 to Tnn+1 are the dilution reaction tube T11. ■21.
..., T1 and analytical reaction tubes '12 to T1n+1'
"22~'2n+1'"°・"m2~Tti
It is distinguished into n+1. That is, a dilution line 1a is formed by the dilution reaction tubes T11゜,..., T1,
Analytical reaction tubes T1° to T1n. 1. T2□〜”2n.1
．． .... An analysis line 1b is formed by 1□ to Tln+1. Therefore, the reaction line 1 is composed of a dilution line 1a and an analysis line 1b which are run in parallel. This reaction line 1 consists of reaction tube arrays L1, L2, .・
It is intermittently driven in the direction of the arrow M shown in the figure at a pitch corresponding to the interval of . 2 is a first dispensing mechanism, and this first dispensing mechanism 112 sucks the sample liquid from the sampler S through the nozzle 22 using the pump device 21, and transfers it to the dilution line 1.
Reaction tube for dilution of a ■11°T21. . . , and further diluted by injecting a diluting solution such as physiological saline, and then washed in a washing tank P. This series of operations by the first dispensing mechanism 2 is repeated in synchronization with the intermittent operations of the reaction line 1. The sampler S has a plurality of containers containing sample liquids, and is arranged so that the containers containing the sample liquid to be analyzed next are successively positioned at the suction position of the first pipetting machine @2. Driven. 3 is a second dispensing mechanism, and this dispensing 1ili13 is arranged in the moving direction M of the reaction line 1.
In this case, two nozzles 31, 32 are arranged along the nozzles 31, 32 and have mutually independent suction and discharge systems, and a pump device 33 for suction and discharge via these nozzles 31, 32, respectively. This second dispensing mechanism 3 uses the pump device 33 to make one unit of operation correspond to two steps of intermittent operation of the reaction line 1, and uses the cleaning liquid W in the first step to pump the cleaning tank P. After washing the nozzles 31 and 32 with the dilution reaction tubes T1 and T11
In the second step, the contents of the two analysis tubes T1□~' In+16 and T2□
~'2n+1, respectively. 4 and 5 are analytical reaction tubes T1□ to T1o+1 that constitute the analysis line 1b.
．． ■2□~T2o+1. It is a nozzle for injecting reagents into the required items according to the analysis item, method, etc. 6 is an analysis reaction tube TI constituting the analysis line 1b.
2~T1o+1. ■22~T2n+1. This is a nozzle for simultaneously sucking up the contents of one row and sending it to the analyzer A. In addition, 7 is filled with heat transfer liquid and is a reaction tube "11~"
In+1. This is a constant temperature bath for keeping the temperature of the sample liquid, etc. in the reaction tube at a constant temperature. 8 is reaction tube T11~TIn+1°T~T
Cleaning processing section 21 2n+ for cleaning processing of...
It is 1#. The cleaning processing section 8 includes a first cleaning nozzle 81 that spouts city water, a second cleaning nozzle 82 that spouts pure water, and a drying nozzle 83 that spouts hot air for drying. Next, the operation in such a configuration will be explained. The reaction line 1 includes a row of reaction tubes and a line 2. ···death. The interval between the two stubs is one pitch, and the stent is intermittently driven, for example, one stent every second. Now, move one step and move to the first 2 steps as shown in Figure 3(a).
It is assumed that the reaction tube array L1 corresponds to the operating position of the dispensing mechanism 2. At this time, the operating position I[, ll
2 (corresponding to the positions of nozzles 31 and 32, respectively) correspond to reaction tube rows L and L, respectively. In this state, the first dispensing tlA4112
sucks up the sample liquid from the sampler S and transfers it to the reaction tube row L.
The discharge is injected into the dilution reaction tube T11, and the same reaction tube T1 is further injected.
A predetermined amount of diluent is injected into 1 and diluted by jet stirring using the injection force of the injection. At this time, please pay attention to the second part @3
The dilution reaction tube T1 of the front row L is located at the operating position corresponding to the nozzle 32 of
The reagent solution that was injected and diluted in the same manner as described above in the operation before step a is stored. In the first dispensing IllI42, after performing the above-mentioned injection dilution, the next step is moved and the nozzle 22 etc. are cleaned before the reaction line 1 is stopped! Wash with P. (The second dispensing 1lII3 operation during this time will be clarified later, so the explanation is omitted here.)Next, when the reaction line 1 moves one step, the reaction tube array as shown in FIG. L2 corresponds to the operating position I of the first dispensing mechanism 2. In this state, the first dispensing mechanism 2 injects and dilutes the sample liquid into the dilution reaction tube T21 as described above. At this time, the nozzle 3 of the second dispensing mechanism 3
The reaction tube array Ll corresponds to the operating positions m and n2 of 1.32, respectively. Then, the first dispensing I! While performing the above-mentioned operation in 1I42, the second dispensing mechanism 3 dispenses the cleaning liquid W and the cleaning species P.
After cleaning the nozzles 31, 32, etc. using
, ■, and the reaction tube rows located at [112ra and 125 tubes for dilution T1. The contents of T11 are respectively sucked up separately via nozzles 31,32. Further, when reaction line 1 moves one step, Figure 3 (C
), place the reaction tube row L3 in the seventh pipetting machine a2 operating position ■.
, and the reaction tube rows L and 2 correspond to the operating positions 1 and 2 of the second dispensing mechanism 3, respectively. Again, the first
The dispensing mechanism 2 injects and dilutes the sample liquid into the dilution reaction tube T31 in the same manner as described above. During this time, the second dispensing mechanism 3 is used for each dilution tube 1 in the previous step.
25 tube T1. The sample liquid (diluted) sucked up from 1 is passed through nozzles 31 and 32 to the reaction tubes, and is used for the L2 analysis reaction.
"In+1°'2n" is injected in the planned amount sequentially. Therefore, the contents of the dilution reaction tube of dilution line 1a are as follows:
It will be dispensed into the analysis reaction tubes in the reaction tube rows that are shifted one row at a time in the analysis line 1b. Analytical reaction tubes T1□~TIn” where the dispensing was performed in this way
Reagents are injected into the sample liquid in 22 to "2n" at points corresponding to the required reaction time for the relevant analysis item using nozzles 4, 5, etc., and all items are sucked up at once by nozzle 6 and sent to analyzer A separately. The data is sent to the system and analyzed by the analysis system for each item. In the cleaning process 18, the empty reaction tube is subjected to cleaning, drying, etc., using cleaning nozzles 81, 82, drying nozzles 83, and the like. The reaction tube moving between at least the operating position I of the first dispensing mechanism 2 and the nozzle 6 position is immersed in a constant temperature bath 7 and is controlled to a predetermined temperature. In this way, since the dilution line 1a that moves with the analysis line 1b is provided in correspondence with the analysis line 1b, the sample is diluted in the reaction tube of the dilution line 1a.
A dilution line 1a containing a diluted sample moves in synchronization with the analysis line 1b. Therefore, dispensing of the diluted sample to the analysis line 1b is not limited to one specific location where dilution is performed, but is performed at two appropriate locations on the analysis line 1b. Therefore, the time associated with dispensing diluted samples is reduced and the efficiency of analytical measurements is also increased. Note that in the above, diluted samples are simultaneously dispensed from the dilution line to the analysis line in two rows, and the operation of the diluted sample dispensing system, that is, the dilution from the dilution line, is performed in two steps of moving the analysis line. All the operations of aspirating the sample, discharging the diluted sample to the analysis line, and cleaning the dispensing system were performed, but since the dilution line and analysis line are synchronously linked, dispensing the diluted sample is It is possible to perform this at multiple locations as required on the analysis line. Further, the arrangement and configuration of the dilution line and the analysis line are not limited to those in the above embodiments, as long as the dilution line and the analysis line are synchronized and interlocked. In addition, the present invention can be implemented with various modifications without changing the gist thereof. [Effects of the Invention] According to the present invention, there is no restriction on the dispensing position of the diluted sample,
It is possible to provide an automatic chemical analysis table that can improve the efficiency of analytical measurements by allowing diluted samples to be dispensed at multiple positions on an analysis line consisting of reaction tubes for analysis. 4. Brief explanation of the drawings Fig. 1 is a schematic configuration diagram schematically showing the system configuration in an embodiment of the present invention, and Fig. 2 is a schematic view of the main parts from information to explain the configuration of the embodiment. Figure 3(a)-(
C) is a diagram for explaining the operation of the same embodiment. 1...Reaction line, L1~,...Reaction tube row, T11~D□. +1・・・Reaction tube, 1a
...Dilution line, ■11 to ■1...Reaction tube for dilution, 1b...Analysis line, T to TT
~■ 12 In+1・22 2n+1
・ ”” ・ Tm2~Tr6n+1... Analysis reaction tube, 2... First dispensing i structure, 3...
...Second dispensing mechanism, 4.5... (for dispensing) nozzle, 6... (for analysis) nozzle, 7...
...Circulation tank, 8...Cleaning processing section.

Claims (1)

[Claims] In an automatic chemical analyzer for automatically performing measurement and analysis of a plurality of items on a plurality of samples, a dilution line comprising an array of dilution reaction tubes used for diluting the sample and containing the diluted sample; A multi-channel analysis line in which analysis reaction tubes containing a reaction solution and used for predetermined measurement and analysis are arranged; a driving means for driving the dilution line and the analysis line in conjunction with each other; An automated chemical analysis characterized by comprising means for dispensing the diluted sample in the dilution reaction tube of the dilution line into the analysis reaction tube of a plurality of channels corresponding to the analysis line in conjunction with the operation of the means. Device.