JPS6112699B2 - - Google Patents
Info
- Publication number
- JPS6112699B2 JPS6112699B2 JP49089739A JP8973974A JPS6112699B2 JP S6112699 B2 JPS6112699 B2 JP S6112699B2 JP 49089739 A JP49089739 A JP 49089739A JP 8973974 A JP8973974 A JP 8973974A JP S6112699 B2 JPS6112699 B2 JP S6112699B2
- Authority
- JP
- Japan
- Prior art keywords
- membrane
- blood
- fluid
- glandular
- cellular material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000012528 membrane Substances 0.000 claims description 58
- 239000000463 material Substances 0.000 claims description 57
- 230000000762 glandular Effects 0.000 claims description 33
- 239000012530 fluid Substances 0.000 claims description 27
- 210000004369 blood Anatomy 0.000 claims description 25
- 239000008280 blood Substances 0.000 claims description 25
- 230000017531 blood circulation Effects 0.000 claims description 18
- 239000012982 microporous membrane Substances 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 description 48
- 210000004027 cell Anatomy 0.000 description 34
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 22
- 210000004907 gland Anatomy 0.000 description 20
- 235000015097 nutrients Nutrition 0.000 description 14
- 210000000056 organ Anatomy 0.000 description 14
- 102000004877 Insulin Human genes 0.000 description 11
- 108090001061 Insulin Proteins 0.000 description 11
- 229940125396 insulin Drugs 0.000 description 11
- 239000006227 byproduct Substances 0.000 description 10
- 239000002699 waste material Substances 0.000 description 10
- 239000000126 substance Substances 0.000 description 9
- 210000003462 vein Anatomy 0.000 description 8
- 210000001367 artery Anatomy 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 241001465754 Metazoa Species 0.000 description 6
- 206010012601 diabetes mellitus Diseases 0.000 description 5
- 239000011148 porous material Substances 0.000 description 5
- 210000004153 islets of langerhan Anatomy 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 210000000496 pancreas Anatomy 0.000 description 4
- 238000007789 sealing Methods 0.000 description 4
- 230000005856 abnormality Effects 0.000 description 3
- 239000000427 antigen Substances 0.000 description 3
- 102000036639 antigens Human genes 0.000 description 3
- 108091007433 antigens Proteins 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 239000005556 hormone Substances 0.000 description 3
- 239000002609 medium Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 239000006163 transport media Substances 0.000 description 3
- 210000000707 wrist Anatomy 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 239000011810 insulating material Substances 0.000 description 2
- 230000001404 mediated effect Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 206010010071 Coma Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000004872 arterial blood pressure Effects 0.000 description 1
- 210000003719 b-lymphocyte Anatomy 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000003372 endocrine gland Anatomy 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Landscapes
- External Artificial Organs (AREA)
- Prostheses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49089739A JPS6112699B2 (enrdf_load_stackoverflow) | 1974-08-05 | 1974-08-05 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49089739A JPS6112699B2 (enrdf_load_stackoverflow) | 1974-08-05 | 1974-08-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5119397A JPS5119397A (enrdf_load_stackoverflow) | 1976-02-16 |
| JPS6112699B2 true JPS6112699B2 (enrdf_load_stackoverflow) | 1986-04-09 |
Family
ID=13979121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP49089739A Expired JPS6112699B2 (enrdf_load_stackoverflow) | 1974-08-05 | 1974-08-05 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6112699B2 (enrdf_load_stackoverflow) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1213404A (en) * | 1981-11-13 | 1986-11-04 | Theodore E. Spielberg | Ultrafiltering hybrid artificial organ |
| FR2531333B1 (fr) * | 1982-08-09 | 1986-04-04 | Centre Nat Rech Scient | Pancreas bio-artificiel a ultrafiltration |
| JPS59139273A (ja) * | 1983-01-29 | 1984-08-10 | 東洋紡績株式会社 | ハイブリツド型人工膵臓装置 |
| JP2023500014A (ja) * | 2019-08-12 | 2023-01-04 | エファレント ラブス，インコーポレイテッド | 生理的変化を監視するためのウェアラブルデバイスおよび使用方法 |
-
1974
- 1974-08-05 JP JP49089739A patent/JPS6112699B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5119397A (enrdf_load_stackoverflow) | 1976-02-16 |
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