JPS608221A - Drug against athelete's foot - Google Patents

Abstract

PURPOSE:A remedy for athelete's foot for inhibiting growth of Trichophyton, remedying athlete's foot completely for a short period, containing an aromatic halide as a main component. CONSTITUTION:A remedy against athlete's foot using an aromatic halide wherein hydrogen linked to a benzene ring is replaced with a halogen element, as a main component. Athlete's foot is a skin disease causing lesion by Trichophyton, since Trichophyton lives in the thick part of corneum in the skin, a drug is slightly penetrated into it, and athlete's foot is not remedied completely. When the aromatic halide (e.g., monochlorobenzene) is used, it was found to give more excellent effect than existing external preparation, and extremely short period of external use. It is considered that the aromatic halide as a main component has high inhibiting action on Trichophyton, and destroys effectively Trichophyton in corneum because it has high osmetic power.

Description

[Detailed description of the invention] The present invention relates to an athlete's foot medicine.

Athlete's foot is a type of skin disease, and lesions are caused by the fungus Lepidoptera. This bacterium is found in the thick part of the horny layer of the skin,
For example, it is easy to get injured on foot marks or palms.5. In the case of the feet, several small welts form on the arch of the soles of the rhinoceroses, and as these scabs turn into pox, they gradually become sore that the skin becomes moss-covered. become. In addition to this, there is also J5 athlete's foot between the fingers or on the nails.

Various types of athlete's foot medicines have been reprinted, and most of them are external medicines. All conventional topical medicines inhibit the growth of white W fungi in test tubes.

It is a white defect agent. However, these conventional external medicines have the drawback of not completely curing athlete's foot.

This was because the white W fungus was parasitic in the thick part of the stratum corneum, making it difficult for the drug to penetrate. Furthermore, among the white spasmodic bacteria, it is often caused by gypsum and gypsum rods, which are relatively resistant to drugs. Griseofulvin is known as a one-way drug, but when treating athlete's foot with griseofulvin, it has the disadvantage that it must be administered indoors for a very long period of time, for example, several months.

The inventor of the present invention has discovered that aromatic halides such as monochlorobenzene have an extremely excellent action against white blight. Based on this knowledge, the present invention (J) The object of the present invention is to provide a medicine for athlete's foot that uses an aromatic halide to completely cure athlete's foot in a very short period of time.

The present invention will be explained in detail below using examples.

The inventor of the present application prepared a liquid athlete's foot having the following composition.

98% monochlorobenzene, 10 parts by weight, 0.3% pure water, 10 parts by weight, nitanol, 10 parts by weight, Zardel acid powder) 2 parts by weight. Applied externally to patients. This patient has been suffering from white nails due to hives for about 5 years, and although he has used various topical medications, he has not been completely cured, and every year from early spring to autumn, quite severe lesions appear on his toes. It is occurring between.

An athlete's foot medicine having the composition described below was applied to the toes between the toes using a brush. Please note that the medicine mentioned in item 1 should be left undisturbed and then divided into two layers.
＜Shake it up and use it. The first step was to apply mulberry to the area where the water roots had been crushed. Then, the moist lesion gradually became dry. The above mulberry coating is 1113
I went around. After the 72nd day, the itching between the toes disappeared, and the size of the lesion between the toes gradually became smaller, and after 5 days, the lesion had become very small. After the 6th day, the medicine was applied three times a day, and on the 10th day, the itching in the mouth completely disappeared, and the affected area returned to its original smooth, flaky appearance.

As described above, according to the athlete's foot medicine according to the present example, a more remarkable effect can be obtained compared to conventional external medicines, and the period of external application is also shorter than that of conventional external medicines. has been proven. This is due to the anti-inflammatory action of monochlorobenzene, the main ingredient contained in the above medicine.
Moreover, this monochlorobenzene has a high penetrating power, so it is thought that this is because it can effectively kill the native bacteria that are parasitic in the stratum corneum.

Although the present invention has been described above with reference to embodiments, the present invention is not limited to these embodiments, and various modifications can be made based on the technical idea of the present invention. For example, in the above example, monochlorobenzene (CH5Cj2) is used as the main component, but this monochrome L''
Nobrolobenzene (CHsBr) may be used instead of benzene. In addition, the substitution position of the halogen element in these aromatic halides is ortho, meta,
It is possible to use various isomers of J: at any position of para.

The above-mentioned J: Sea urchin/J athlete's foot medicine uses as a main component an aromatic halide in which the hydrogen bonded 3-1 to the benzene ring is replaced with a halogen element. Therefore, according to the present invention, it is possible to provide a medicine for athlete's foot that has a high potency and can completely cure athlete's foot in a short period of time.

Agent Toshi Osamu Matsu

Claims (1)

[Claims] An athlete's foot medicine characterized by using as a main ingredient an aromatic halide in which hydrogen bonded to a benzene ring is replaced with a halogen element.