JPS605797B2 - Microinjection pump device - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a microinjection pump device used to continuously inject infusions into the human body for a predetermined period of time, and in particular, to control the amount of infusions injected according to a predetermined program.
The present invention relates to a pump device that consumes less power, is portable, and can be used for a long time.

Today, in the medical field, for example, nutritional support for newborns,
BACKGROUND OF THE INVENTION Various constant flow infusion pumps have been developed and used for administering various nutritional supplements and drugs, such as high-calorie infusions to patients with diabetes, administration of anticancer drugs, and insulin administration to diabetic patients. In this way, when the pump is used as a treatment device as described above, it is possible to create an infusion pattern that matches the rhythm of the body by changing the amount of infusion injected over time, and it can be worn on the human body with extremely low power consumption. It is required to have a configuration that can be used for a long time. For example, in insulin therapy for diabetic patients, insulin is currently administered several times a day. If it becomes possible to attach the device to the human body and use it continuously for a long period of time, it will improve the ability to control blood sugar levels as a medical device, avoid the risk of overdosing insulin, and allow patients to freely lead social lives. Conventionally, pump devices used in this type of medical equipment use a mainspring as the driving force, and this mainspring is coupled to a transmission device consisting of large and small gears. A clock mechanism is applied in which an escapement mechanism using a balance is connected to a part of the transmission device, and the rotational force of this clock mechanism is used to rotationally drive the rollers that pump the fugitive tube. The drug injection device was published in Utility Model Publication No. 43-20628 and Special Publication No. 4
No. 9-38153.

A pump device configured with a clock mechanism as a driving source has the advantage that it is easy to rotate the rotor that performs the pump operation at a constant speed, and it is also possible to inject a fixed amount of infusion over a long period of time without using a power source. However, when adjusting the amount of infusion injected, a clock escapement mechanism using a balance wheel is used to regulate the speed of the rollers, making it difficult to adopt an automatic speed regulating mechanism. Pump devices configured with a mechanism as a drive source were not equipped with an automatic wheel fluid injection amount control device, and the only way to adjust the infusion amount was to manually adjust the balance each time. , the inventors have overcome all the problems of conventional infusion pump equipment, and have developed a pump that can be used for programmable infusion volume control, consumes low power when worn on the human body, and can be used continuously for long periods of time. As a result of intensive research to obtain a device, an escape mechanism containing a small electric motor was incorporated as a speed regulating mechanism for a pump device whose driving source is a clock mechanism, and the rotation speed of this small electric motor was programmed in advance. By automatically controlling based on various infusion patterns, it is possible to achieve the ideal injection of drug solutions that match the physiological conditions of the human body, and to operate these automatic control units with minimal power consumption. It has been found that an infusion pump device with significantly improved performance can be obtained.

Therefore, the general object of the present invention is to employ a winding clock mechanism as the power source of a pump device, and to employ an electric motor as a speed governor of this clock mechanism, so that the rotational speed of the electric motor is adjusted to a predetermined infusion rate. To provide a microinjection pump device with excellent control performance that can make the injection volume variable by automatically controlling it according to a program based on a pattern, and achieve continuous injection of infusions, etc. over a long period of time with low power consumption. .

The main object of the present invention is to consist of a pump device and a mainspring type drive device for operating the pump device.
A speed governor consisting of an electric motor is connected to the type drive device, and a rotation speed control device is attached to the speed governor to control the electric motor.
An object of the present invention is to provide an infusion pump device that is characterized by controlling the amount of water.

In the above-mentioned injection pump device, the pump device has a structure in which an elastic tube is wound around a rotating body having a plurality of rollers arranged on the same circle, or the elastic tube is connected to a roller and a roller. - It is preferable to use a roller pump which is inserted between the lug guides and presses the tube with a roller. Further, as this pump device, a rotary pump or a reciprocating bed pump can also be applied. The mainspring type drive device consists of a mainspring and a gear mechanism that transmits the power of the mainspring to the rotating body for driving the pump.
It can be constructed by connecting a speed governor to a part of the gear mechanism via an escapement mechanism.

The rotational speed control device includes an electric motor drive control section, a timer control section that sets the period of the infusion pattern, a step data input section that divides and sets the period of the infusion pattern into multiple steps, and a one-step system that stores the infusion amount data. and a storage circuit section that sends the data to the electric motor drive control section at each time.

The escape mechanism includes a worm and a worm gear, and can be constructed by directly connecting the worm to an electric motor of a speed governor.

In this case, it is preferable to use a pulse motor or a direct current motor as the electric motor. Alternatively, the escapement mechanism is
It is also possible to have a configuration in which the rotating body is made of a Geneva gear, a part of the rotating body is engaged with the groove of the Geneva gear, and the electric motor of the speed governor is directly connected to the rotating body.

In this case, the electric motor uses a pulse motor or a DC motor, and converts the infusion volume data signal from the storage circuit into a rotational speed control signal proportional to this signal, and drives the electric motor. It is preferable to configure the control section. The timer control section consists of a timer oscillator activated by a start signal, a frequency converter, and a dendrite.
The output frequency of the timer oscillator can be configured to be divided into a frequency proportional to the step data and supplied to the storage circuit section.

In addition, the step data input section is equipped with a step setting switch, and converts the output frequency of the timer oscillator of the timer control section in accordance with the step data, and also drives the electric motor for each infusion pattern period by using the stored data in the storage circuit section. It can be configured to generate a step signal to be sent to the control unit.

It is preferable that the infusion amount data is sequentially supplied to the storage circuit and stored from an infusion amount data input unit equipped with an infusion amount data setting switch.

Further, the storage circuit unit includes a storage circuit for storing the infusion volume data and a data latch circuit, and can be configured to send the infusion volume data signal to the electric motor drive control unit in accordance with the step signal. . Next, embodiments of the infusion pump device according to the present invention will be described in detail below with reference to the accompanying drawings.

1 and 2 show embodiments of the pump device of the present invention, which include a pump section 10, a mainspring that drives this pump section 10, a type drive section 12, a mainspring, and a speed regulator of the type drive section. A speed governor mechanism section 14 including an escapement mechanism that performs the following, and a speed governor mechanism i4
It basically consists of a circuit section 16 for automatically controlling the pump section 16, and a power supply section 18, and is further provided with a chemical storage tank 20 that is compatible with the pump section 10.

Note that these components are all housed in a single casing 22 and configured to be conveniently portable.
In FIG. 1, a pump part 1 includes a rotating body 26 with a plurality of rollers 24 arranged concentrically, an elastic tube 28 wound around the rotating body 26, and an elastic tube 28.
The tube holder 32 bridges and fixes tube stoppers 30, 30 to both ends of the tube holder 32, and a support shaft 34 of the rotary body 26 is connected to a clockwork drive unit 12, which will be described later.

Note that one end of the elastic tube 28 is connected to the chemical solution storage tank 20.
Ren said. In this way, the pump unit 10 can be constructed as a generally known roller pump, but other types such as a rotary pump or a reciprocating pump that can achieve pumping action using rotational motion are also applicable. In FIG. 2, the mainspring type drive unit 12 includes a mainspring 36 and a first large gear 38 coaxially arranged with the mainspring 36.
, a second small gear 40 that meshes with the first large gear and is coaxially arranged with the support shaft 34 of the pump section, a second large gear 42 that is coaxially arranged with the second small gear, and a second large gear. A third small gear 44 that meshes with the third small gear, a third large gear 46 that is coaxially arranged with the third small gear, a fourth small gear 48 that meshes with the third large gear, and a third small gear that is coaxially arranged with the fourth small gear. The fourth large gear 50 and the fourth
The fifth small gear 52 meshes with the large gear.
The speed regulating mechanism 14 is coupled to the small gear 52 .

The speed regulating mechanism 14 includes a worm gear 54 coaxially arranged with the 54th gear 52, a worm 56, and a worm 56.
6 and an electric motor 58 directly connected to the motor 6.

As the electric motor 58, a small DC motor or a pulse motor is preferably used, which is advantageous in terms of controllability and power consumption. As an alternative, the adjustment mechanism 14 has a Geneva gear 60 coaxially disposed as an escape mechanism on the fifth small gear 52, and this Geneva gear 60
It is also possible to engage a rotary plate 64 with a pin that provides rotational motion in the groove portion 62 of the rotary plate 64, and to connect the electric motor 58 to the rotary plate 64.

As the electric motor 58 used in this case, a small DC motor or a pulse motor is suitably employed as described above. Furthermore, an escape wheel is arranged coaxially with the fifth small gear 52,
It is also possible to configure the speed regulating mechanism 14 by connecting an electric motor that performs reverse reciprocating motion via an ankle.

As is clear from the above configuration, according to the present invention, the speed control of the mainspring and the drive unit 12 can be easily achieved by controlling the rotational speed of the electric motor 58, and as a result, the speed control of the mainspring and the drive unit 12 can be easily achieved by controlling the rotational speed of the electric motor 58. Moreover, it can be driven for a long time by the mechanical force of the drive unit 12, and the electric motor 58 of the speed regulating mechanism 14 can use a low-output ultra-small electric motor, so it can be driven with extremely small electric power. It becomes possible to maintain a wide range of control performance.

Next, the automatic control circuit 16 of the infusion pump device according to the present invention having the above-described configuration will be explained.

FIG. 4 is a system diagram showing an example in which a pulse motor is used in the speed governor mechanism among automatic control circuits that can be suitably used in the speed governor mechanism 14 of the embodiment shown in FIG. Reference numeral 70 denotes a memory circuit, and this memory circuit 7 stores infusion volume data DIA supplied from an infusion volume data input section that determines an infusion pattern, and is used to store infusion volume data DIA supplied from an infusion volume data input section that determines an infusion pattern, and performs operations based on an output signal from a timer control circuit to be described later. The infusion amount data in the storage circuit 70 is sequentially transferred to the data latch circuit 72, and further sent to the motor drive control circuit which converts the transferred infusion amount data signal DIA into a rotation drive signal for the electric motor proportional to the transferred infusion amount data signal DIA.

Note that the infusion amount data input section is provided with a switch for appropriately setting infusion amount data. The timer control circuit is composed of a control circuit 74, a timer oscillator 76, a frequency converter 78, and a frequency divider 80.

Now, when the start signal STR is supplied to the control circuit 74, the timer oscillator 76 is activated by the output signal of the control circuit 74.
is activated, and the output pulse signal of the timer oscillator 76 is supplied to the frequency converter 78. The frequency converter 78 is provided with a step data input section equipped with a step setting switch, and converts the pulse signal supplied from the timer oscillator 76 into a ratio proportional to the step data DSTP of the infusion pattern supplied from the step data input section. The pulse signal is converted into a pulse signal having a certain frequency, and then the frequency of the pulse signal is divided by a frequency divider 80, and the obtained signal is sent back to the control circuit 74. In the control circuit 74,
Based on the frequency-divided pulse signal, the liquid volume data in the storage circuit 70 is sequentially transferred to the data latch circuit 72, and then the liquid volume data signal DIA transferred to the data latch circuit 72 constitutes a motor drive control circuit. The signal is sent to the frequency converter 82. In the motor drive control circuit, the start signal STR passes through the control circuit 74 and operates the pump oscillator 84 simultaneously with the timer oscillator 76, and the output signal of the pump oscillator 87 is also supplied to the frequency converter 82.

Therefore, in this frequency converter 82, the data latch circuit 7
The infusion amount data signal DIA sequentially sent from 2 is converted into a frequency proportional to the infusion amount data signal DIA, and is inputted to the next pulse motor drive logic circuit 86. In this way, the pulse motor 58 is driven based on the output signal of the pulse motor drive logic circuit 86, and the drive of the pulse motor 58 operates the mainspring and the pump section 10 via the formula drive section 12. The medicinal solution in the medicinal solution storage tank 20 can be pumped according to the infusion amount data stored in the storage circuit 70.

Note that it is preferable to supply the pump oscillator 84 with a signal PSP for adjusting the oscillation frequency of the pump oscillator 84 for fine adjustment of the rotation speed of the pump, that is, the rotation speed of the pulse motor. Further, in order to stop the operation of the automatic control circuit described above, a stop signal STP is sent to the control circuit 74.
This can be easily achieved by supplying FIG. 5 is a system diagram showing an example of an automatic control circuit that can be suitably used for the speed governor mechanism 14 of the embodiment shown in FIG. The configurations and functions of the circuit section and timer control circuit section are exactly the same as those of the control circuit shown in FIG. 4 above.

However, in this embodiment, the control circuit 74 sequentially transfers the liquid volume data in the storage circuit 70 to the data latch circuit 72 based on the pulse signal frequency-divided by the frequency divider 80, and then The infusion amount data signal DIA transferred to the motor drive control circuit D
- Send to A converter 88. The motor drive control circuit is composed of the D-A converter 88 and the amplifier 90.
The A converter 88 converts the infusion amount data signal DIA successively sent out from the data latch circuit 72 into an analog voltage signal proportional to the infusion amount data signal DIA, and then drives the DC motor 58 based on the amplified signal via the amplifier 90. In this way, by driving the DC motor 58, the pump 10 is operated via the mainspring and the type drive unit 12, and the chemical solution storage tank 20 is operated.
The medicinal solution within can be pumped according to the infusion volume data stored in the storage circuit 70.

Note that in this embodiment as well, the control circuit 74 receives the stop signal S.
By supplying TP, the operation of the automatic control circuit and the pump section 10 can be stopped immediately.

In the embodiment of the automatic control circuit described above, the memory circuit 7
Although a method has been adopted in which predetermined transfusion volume data is sequentially set, it is also possible to configure such that the transfusion volume data is fixedly stored in advance in the memory circuit 7.

FIG. 6 shows a waveform diagram of an infusion pattern by the infusion pump device according to the present invention, and the infusion amount data in the storage circuit is determined by the frequency divider output signal of the timer control section (see FIG. 6a). The liquid is sequentially sent to the electric motor drive control section, and the pump section can dispense the liquid to a predetermined level (see FIG. 6b).

As is clear from the above, in the injection pump device according to the present invention, the pump is driven by the mechanical power of the spring, and the amount of liquid dispensed by the pump is controlled by the low-output four-wheel drive. Since it uses a type electric motor to programmatically achieve the desired wheel fluid pattern, it can be used for a long time with a small dry battery as a power source, and the mainspring and type drive mechanism are also similar to those used in watches. By applying the mechanism, it is possible to obtain a large output in a small size, and the automatic control circuit of the small electric motor can also be made smaller by using an integrated circuit, making it possible to create a compact infusion pump device that is convenient to carry as a whole. Obtainable. Although the preferred embodiments of the present invention have been described above, it goes without saying that various design changes can be made without departing from the spirit of the present invention.

[Brief explanation of the drawing]

FIG. 1 is a plan view showing an embodiment of the configuration and arrangement of the pump section side of the microinjection pump device according to the present invention, and FIG. 2 is the configuration of the drive control mechanism side that drives and controls the pump section shown in FIG. 1. FIG. 3 is a plan view showing another example of the speed regulating mechanism of the mainspring and type drive unit shown in FIG. 2;
Fig. 4 is a system diagram showing an example of an automatic control circuit that controls the mainspring shown in Fig. 2 and the tuning mechanism of the type drive unit, and Fig. 5 is another embodiment of the automatic control circuit that controls the speed governor mechanism. FIG. 6 is a waveform diagram of a ring liquid pattern achieved by the pump device according to the present invention. 10...Pump section, 12...Spring-type drive section, 14...Governing mechanism, 16...Automatic control circuit section, 18...
...Power supply section, 20...Medical solution storage, 22...
...Casing, 24...Roller, 26...Rotating body, 28
...Elastic tube, 30...Tube stopper, 32...
...Tube holder, 34...Shito, 36...Spring, 38...First gear, 40...
Second small gear, 42...Second large gear, 44...
・34th gear, 46... 3rd large gear, 48.
...44th gear, 50...4th large gear, 52...5th small gear, 54...worm gear, 56...worm, 58 ......Electric motor, 60...Geneva gear, 62...Groove, 6
4... Rotating plate, 70... Memory circuit, 72...
. Data latch circuit, 74... Control circuit, 76...
・Timer oscillator, 78... Frequency converter, 80
...Minimum unit, 82...', frequency converter, 84...
Pump oscillator, 86...pulse motor drive logic circuit,
88...D-A converter, 90...Amplifier. FIG.
l FIG. 2 FIG. 3 FIG. MuFIG. 5 F! G. 6

Claims (1)

[Claims] 1. Consisting of a pump device and a clockwork drive device that operates the pump device, the clockwork drive device is connected to a speed governor made of an electric motor, and the speed governor is connected to a rotation speed control device. A microinjection pump device, characterized in that the microinjection pump device is equipped with a device to control the electric motor. 2. The microinjection pump device according to claim 1, wherein the pump device is an elastic tubular roller pump. 3. The microinjection pump device according to claim 1, wherein the pump device is a rotary pump in which an impeller for changing volume is disposed within a circular casing. 4. A mainspring drive device consists of a mainspring and a gear mechanism that transmits the power of the mainspring to a rotating body for driving a pump, and a speed governor is connected to a part of the gear mechanism via an escapement mechanism. A microinjection pump device according to any one of claims 1 to 3. 5. The rotational speed control device includes an electric motor drive control section, a timer control section that sets the period of the infusion pattern, a step data input section that divides and sets the period of the infusion pattern into multiple steps, and a one-step input section that stores the infusion amount data. 5. The microinjection pump device according to claim 1, further comprising a memory circuit section that sends the data to an electric motor drive control section at each time. 6. The microinjection pump device according to claim 4, wherein the escape mechanism is composed of a worm-worm gear, and the electric motor of the speed governor is directly connected to the worm shaft. 7. The escapement mechanism includes a Geneva gear, a part of a rotating body is engaged with a groove of the Geneva gear, and an electric motor of a speed governor is directly connected to the rotating body, as described in claim 4. Microinjection pump device. 8 The electric motor of the speed governor consists of a pulse motor,
A motor drive control unit is configured to convert the infusion volume data signal from the storage circuit unit into a frequency proportional to this signal, convert the obtained signal into a pulse train necessary for driving the pulse motor, and drive the pulse motor. A microinjection pump device according to any one of claims 1, 5 to 7. 9. The electric motor of the speed governor consists of a DC motor, and the motor drive control unit is configured to drive the DC motor by converting the infusion volume data signal from the storage circuit unit into an analog voltage signal proportional to this signal. Claim 1
7. The microinjection pump device according to any one of Items 5 to 7. 10 The timer control section consists of a timer oscillator activated by a start signal, a frequency converter, and a frequency divider, and divides the output frequency of the timer oscillator into a frequency proportional to the step data and supplies it to the storage circuit section. A microinjection pump device according to claim 5, configured as follows. 11 The step data input section is equipped with a switch for step setting, and converts the output frequency of the Tama oscillator of the timer control section in accordance with the step data, and also controls the electric motor drive using the data stored in the storage circuit section for each infusion pattern cycle. 11. The microinjection pump device according to claim 5 or 10, wherein the microinjection pump device is configured to generate a step signal for sending the microinjection pump to the patient's body. 12. The trace amount data set forth in claim 5 or 8, wherein the infusion amount data is sequentially supplied to and stored in a storage circuit via an infusion amount data input unit equipped with an infusion amount data setting switch. Infusion pump equipment. 13. The storage circuit unit includes a storage circuit for storing transfusion volume data and a data latch circuit, and is configured to send the transfusion volume data signal to the electric motor drive control unit in accordance with the step signal. Section 5, Section 8 to Section 1
3. The microinjection pump device according to any of Item 2.