JPS5998663A - Health food effective for prevention and remedy of adult disease - Google Patents

Abstract

PURPOSE:To obtain a food having high preservability and effective to adult diseases, by mixing the extract of Fomes japonicus and oil or fat containing eicosapentaenoic acid, and if necessary, adding a natural antioxidant to the mixture. CONSTITUTION:Fomes japonicus is extracted with hot water, concentrated under normal or reduced pressure, and dried to obtain powdery extract. The extract is mixed with an oil or fat containing eicosapentaenoic acid. The amount of the oil or fat is >=20pts. based on 100pts. of the sum of both components. It is preferable to add about 0.2%, based on the oil or fat containing eicosapentaenoic acid, of a natural antioxidant such as tocopherol to improve the preservability. The oil or fat containing eicosapentaenoic acid is e.g. that of blue fish such as sardine, mackerel, etc. or of marine animals living on fish.

Description

DETAILED DESCRIPTION OF THE INVENTION This invention provides a method for preventing adult diseases in which an extract of C. chinensis and an oil containing all of eicosapencitric acid are mixed.
It relates to health foods that are effective for improvement.

However, the entire purpose of this invention is to provide a health food that has both the effects of C. chinensis and eicosapentaenoic acid against adult diseases and has a good shelf life.

The inventors of this invention have previously discovered that the extract of C. chinensis has a blood pressure lowering effect and that it has an effective effect on adult diseases such as hypertension, hyperlipidemia, arteriosclerosis, and intravascular thrombosis. etc. (°Patent Application 1986-455)
58, patent application No. 1984-133728, patent application No. 1987-187
752 etc.).

The inventors of this invention discovered that when mixed with an oil containing eicosapentaenoic acid, which further enhances the effect of this mushroom on adult diseases, the preservability of the oil improves, and thus completed this invention.

Eicosapentaenoic acid is used when prostaglandins are synthesized in the body, and has the function of inhibiting platelet aggregation and lowering blood cholesterol levels. Therefore, ingesting fats and oils containing eicosapentaenoic acid can lead to hypertension. is known to be effective against adult diseases such as hyperlipidemia, hypercholesterolemia, cerebral infarction, and myocardial infarction (food industry
(September 1981 second issue, etc.)

However, eicosapentaenoic acid is an unstable fatty acid having five double bonds and is therefore highly susceptible to deterioration. Therefore,
If oils and fats containing eicosabencitric acid are left in the air, they will deteriorate in a few days and become unusable.

Moreover, this modification cannot be prevented even by adding tocopherol, a natural antioxidant.

Still, spoiled fats and oils not only cause diarrhea and abdominal pain, but also
It has harmful effects such as damaging cell walls and hardening blood vessels, which is thought to increase blood pressure and make blood vessels more susceptible to damage, worsening adult diseases and accelerating aging.

Therefore, even if fats and oils containing eicosapentaenoic acid are ingested for the purpose of preventing or reversing adult diseases, there is a risk that they may actually worsen the disease.

A health food of the present invention is a combination of an extract of Mandarin mushroom and an oil containing eicosapene citric acid.

Therefore, the health food of this invention has both the effects of C. chinensis and the effects of eicosapentaenoic acid,
It is effective in preventing and improving adult diseases such as hypertension, hyperlipidemia, hypercholesterolemia, arteriosclerosis, cerebral infarction, myocardial infarction, and vascular thrombosis.

Moreover, this health food has an extremely long shelf life.

In other words, oils and fats containing eicosapentaenoic acid deteriorate quickly; for example, when left at 32°C as shown in the test example, a raw, rotten odor develops within a few days, and after a week it becomes obvious. A rotten odor can be felt, and after 10 days, the rotten odor becomes so strong that it becomes unbearable to put into the mouth.

This tendency is not improved by adding tocopherol, a natural antioxidant.

However, when we add stone mushrooms, it takes 11 days for the mushrooms to begin to deteriorate and feel raw, and it takes about 3 weeks for the rotten odor to become evident, and the rotten odor is so strong that it becomes unbearable to put into the mouth. It takes about 30 days to reach the desired temperature, and the shelf life is about three times longer than when using only oil and fat without adding anything.

What's more, when tocopherol is added at the same time as the stone mushroom, the shelf life is even better, and the number of days it takes to notice a distinct odor of spoilage is five times that of fats and oils that do not contain any calories.

In this way, the health food of this invention has a very good shelf life even though it contains eicosapentaenoic acid, and there is no need to worry about it deteriorating even if stored for a long time and aggravating adult diseases. The health food of the present invention is produced by completely mixing the extract of C. chinensis and fats and oils containing eicosapene citric acid, and if necessary, an emulsifying substance such as lecithin is added during mixing. .

In addition, it is desirable to add and mix natural antioxidant substances in order to improve the preservability, and if you use all the tocopherol as a natural anti-oxidant substance, you can extend the preservability and at the same time obtain the effect as vitamin E. It becomes even more deplorable. It is also possible to use natural fats and oils, such as wheat germ oil containing tocophyne.

The extract of C. monocytogenes of this invention refers to C. monocytogenes (
It refers to the extract of the genus Stonemaceae extracted with hot water. If you add 1 tsp of extract liquid, you can make shoes under normal pressure or under reduced pressure.
It is desirable to use a powder that has been concentrated by membrane concentration, further concentrated by dialysis, ion exchange resin, etc. if necessary, and dried by, for example, spray drying, vacuum drying, freeze drying, or the like.

However, oils and fats that completely contain eicosabentaenoic acid refer to oils and fats that contain eicosapencitric acid as a constituent fatty acid. Oils and fats obtained mainly from marine animals can be used, such as oils and fats of fish that live in the sea, oils and fats of sea animals that regularly eat fish such as fur seals and seals, animal products such as krill, and oils and fats of plankton. Preferably, the method uses all the triglyceride-concentrated fats and oils containing eicosaben citric acid.

Incidentally, the ratio of the extract of C. chinensis and the fats and oils containing all of the eicosabencitric acid can be changed arbitrarily depending on the desired effect, but in order to exert the effects of both to a certain extent, 1100 parts of the extract of both (Heavy IT! Part, the same applies hereinafter), it is desirable that the amount of fats and oils containing eicosapencitric acid is 20 parts or more.

To add tocopherol for the purpose of extending shelf life, around 0.2% of the fat and oil containing eicosapentaenoic acid is sufficient, but in order to have the effect of vitamin E as well, it is necessary to add tocopherol to the desired effect. It is desirable to add more songs as needed.

Next, I will explain the parsimony example.

Sample 1: Fresh fish oil containing 14.3% eicosapentaenoic acid.Sample 2: Fish oil from sample 1 plus 2% tocopherol.Sample 3: 80 parts of the fish oil from sample 1 as described in the examples. Sample 4: Added 20 parts of the extract of C. chinensis to 80 parts of the fish oil added with tocopherol from Sample 2. Added 20 parts of the extract 11 of the D. chinensis described in the examples.Put the above samples 1 to 4 in a small petri dish. The samples were left uncovered in a constant temperature bath where 34C air was refluxed, and the odor when put in the mouth was examined over time by 10 expert panelists.

The values in the table are: no smell of spoilage at all (0), faint smell of spoilage and taste (2), clear smell of spoilage (4), strong smell of spoilage that makes your mouth smell. The average score of 10 people was 2.4.6.
This is the number of days when .

Table: The deterioration odor table of eicosapentaenoic acid-containing oils and fats shows that sample 1 has a rating of 2 where it feels raw, but sample 1 has a rating of 3 days.
It is shown that sample 2 took 2 days, sample 3 took 11 days, and sample 4 took 25 days. Similarly, the number of days when the smell of deterioration is clearly felt (review 1 song 4) is 8 days, 7 days, and 2 days, respectively.
It took 3 days and 40 days, and for the case where the odor was too strong to put in the mouth (tFl+ff16), it took 13 days, 11 days, and 29 days. Although sample 4 was tested for 60 days, the average rating did not reach 6.

Next, an example will be explained.

Ganoderema l!ucidu
The fruiting bodies of m (Fr, )Karst) are crushed and about 2
It is boiled for about 30 minutes with 0 times the amount of water, and then all insoluble matter is separated to obtain an extract.

This extract e is concentrated under total vacuum to a volume of about 15 times smaller, and then freeze-dried to obtain a powdered extract of the L.

Thirty-five parts of the extract of this mantis mushroom was mixed with 60 parts of fish oil, which had been concentrated to have an eicosapene citric acid content of 19.6%, and 5 parts of tocopherol, and the mixture was sealed in soft capsules and used as a health food.

Even when this health food was placed in a constant temperature bath at 34°C for 3 months, no decomposition odor was detected.

Patent applicant: Morinaga & Co., Ltd. Toyo Yakushoku Kogyo Co., Ltd. Procedural amendment (voluntary) 1. Display of incident 1981 Patent Application No. 210015 2. Name of the invention Health foods that are effective in preventing and improving adult diseases 3. Person who makes corrections Relationship to the case Patent applicant Reprint of specification (no change in 'g-)

Claims (1)

[Claims] This health food is effective for preventing and improving adult diseases, and is characterized by a mixture of extracts of C. chinensis and fats and oils containing eicosapentaenoic acid, with addition of natural antioxidant substances as necessary.