JPS598938A - Medical capsule - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a medical capsule for collecting digestive fluids from the body or releasing medicinal fluids.

There are already a number of medical capsules that utilize the capsule body as a cylinder and take in digestive juices and the like into the capsule body by moving a piston within the cylinder. However, this type of medical capsule has a microstructure that can be swallowed, and collection must be controlled from outside the body, so it may not be possible to reliably collect the capsule. For this reason, in the past, the operating state of the capsule was mistakenly seen from outside the body using X-rays, and the photons of the collection operation were confirmed. Consequently, the negative effects of X-ray rays on the human body inevitably arose. Due to the small position of the capsule within the body, it was impossible to accurately confirm the collection operation using X-rays.

SUMMARY OF THE INVENTION Therefore, an object of the present invention is to provide a medical capsule in which collection or release operations can be accurately ICED performed externally without using X-rays.

To achieve the above objects, the present invention provides: 1) a swallowable capsule body having an opening for collection of an object in the body or release of the object into the body; a movable body movably disposed within the capsule body so as to perform the following; and a movable body disposed within the capsule body so as to detect that the movable body has moved to a predetermined position within the capsule body. a moving object detector; a transmission circuit disposed within the capsule body to transmit a detection signal based on the moving object detector to the outside of the body;
This relates to a medical capsule that is characterized by having the following characteristics:

According to the above invention, since the moving object detector and the transmission circuit are provided within the capsule body, it becomes possible to accurately and easily obtain outside the body whether collection or release has been performed without relying on X-rays.

For a long time, referring to FIGS. 1 to 5, one embodiment of the present invention 9'l
Let's talk about medical capsules related to JK.

Figure 2 is a cross-sectional view schematically showing the state before the collection operation of a medical capsule for collecting digestive juices, intestinal juices, etc. from the stomach, duodenum, small intestine, etc., and Figure 2 is the operation of collecting the capsule in Figure 2. It is a sectional view showing a later state.

As is clear from these drawings, the capsule is composed of a synthetic resin capsule body [11], a capsule body (11) which acts as a cylinder, and a synthetic resin movable body (21) which acts as a piston. Body +21 VC Compression coil spring (31) for applying biasing force in the right direction in Figure 1.

The thread (41) serves as a locking member that locks the movable body (21) at a certain position against the biasing force of the spring +31.
A heating filament (5; ), an electric circuit section (81) including a circuit that supplies current to the filament (5) and transmits a detection signal to the outside of the body in response to detection by the moving object detector +71 K, and a power source battery (9). .

To explain each part in more detail, the capsule body +11 is 1
The stone gI11 part is formed into a length of about 3 cm and a diameter of about 8 mm by the combination of the opening a) and the left part (1b) rL
.

The cylinder part has an opening (Ilj) for collecting defrosting fluid.

It has an air discharge opening u11 at its right end.

A moving body (21 is made of synthetic resin and has a cylindrical shape,
It is movably fitted into the cylinder portion of the capsule body tl+. This hollow cylindrical svc is provided with an opening σ2 for taking in digestive fluid when the opening (1) coincides with the cylinder part, and a thread +410 locking member 0 is fixed to the right end of the octopus. In addition, in order to improve the sealing between the capsule body +11 and moving body #21, moving body (2
A silicone O-ring IJ41 is attached to the groove on the outer peripheral surface of No. 1. A cylindrical fixed support member (151) and a compression coil spring (3) are disposed between the stepped portion of the movable body +21, so that
The moving body (21 is always biased to the right in FIG. 1).

However, the thread supported by the fixed support member (151 +41
Since the moving body (2;) is locked by the VC, the thread (4;
) is fused! Now, keep it in the state shown in Figure 1.

The filament (5) is supported by two stems (1).

As is clear from the enlarged view of FIG. 4, part of -f is supported by a reinforcing body (6) made of electrically insulating synthetic resin with low thermal conductivity. Since the reinforcing body (6) is rigidly supported by the stem α6), the reinforcing body (6) does not sag. Therefore, the reinforcing body (6) prevents the filament (5) from sagging. , filament) +51 and thread (41 are arranged perpendicularly to each other, as is clear from FIGS.
Contact or proximity to 5j.

Electrical circuit part (In the 8th month, IC conversion as shown in Figure 5)
A current supply and transmission circuit σ power is also accommodated.

That is, a trunk star U connected in series with the filament (5) and the battery +91, a drive transistor U1 connected in VC between the collector and the base of the transistor A, Drive transistor a
Control signal receiving coil 4 is connected between the base and emitter of 9 to turn on 1, and the collector of transistor 181 and battery 9+ is connected via the contact of switch f211 when transmitting the detection signal. It consists of a capacitor (221) and a feedback coil.

The two coils QO1 are wound around a common ferrite core and are electromagnetically coupled to each other. The filament (5) is also connected between the collector of the transistor a& and [Gt9+T via the contact a of the switch (211).

The moving object detector (71 is disposed at the inner right end of the cuff cell main body fi+ as shown in FIGS. However, the wire connecting the detector (7) and the electric circuit part (8) and the four-ton leaf spring CI that presses the left end of the battery (9)
! A wiring connecting 41 and the electric circuit portion (8) is formed of a conductive layer.

When collecting effusion liquid or the like using a capsule configured as described above, the test subject swallows the capsule in the state shown in Figure 1, and when the capsule reaches the desired position R inside the body, a transmitter outside the body is activated. sends electromagnetic waves from still. Whether the capsule has arrived at the desired position is determined by the elapsed time after swallowing or by an X-ray or the like. When electromagnetic waves are sent from outside the body,
The receiving coils receive this, and the transistor σ sickle turns on.

Electric current is supplied from the battery +91 to the filament) t5+, and the thread (4) is fused by the heat of the filament) +51.
The holding of the movable body (2) by the thread (4) is released, and the movable body (2) moves to the right in FIG. 1 by the force of the coil spring (31). At this time.

The air in the space (2GJ) between the right end of the moving body (21) and the cuff cell body (11) is gradually exhausted by Vc through the opening aII. Therefore, the space (c) functions as an air damper.

The volume of the hollow part &51 of the moving body +21 increases as the moving body (21) moves, so that the inside of the hollow part &51 becomes a reduced pressure state, that is, a negative pressure state.Thus, the moving body (21) is displaced by 5Vc.

When the opening QUI of the capsule body il+ and the opening (121) of the moving body +21 match, the hollow part (c) of the moving body +21
is in communication with the outside of the capsule body ill, that is, the part where digestive juices etc. are present, and the hollow part CI! is in a negative pressure state! 51 K defrosting liquid etc. flows in.

As the movement continues to the final position, the opening (101) is blocked by the moving body (2), and the opening (121 is blocked by the capsule body i).
l+, and the moving body (hollow part 5 of 21) is completely sealed from the outside of the capsule body t'll. When the moving body (21) reaches the final position shown in diagram N2, the moving body (2)
At the right end of the detector (force is pressed, the contact a of the switch Cυ shown in Fig. 5 turns off, and the contact a turns on. As a result,
The circuit of the filament (51) is cut off, and the coil and capacitor Q21 are connected in its place to form a collector-tuned oscillation circuit, and electromagnetic waves are radiated from the body to the outside of the body and received by a receiver outside the body. , it can be said that the collection operation was completed completely.After several hours to several tens of hours, the collected capsule is expelled from the anus through Ih.Therefore, the temperature and discharge pressure were collected. The liquid will be tested.

As is clear from the above, according to this embodiment, the filament (51K) thread (41) is reliably fused.

It is possible to accurately and silently detect from outside the body whether the digestive fluid or the like has been reliably collected by the movement of the moving body (2) based on the operation of the launching circuit. If Ficimen N511
If the body does not send a signal indicating completion after a certain period of time has elapsed since the current was passed, it will be determined that the collection is incomplete. Send again or swallow a new capsule again.

This makes it possible to perform complete sampling.

Although one embodiment of the present invention has been described above, the present invention is not limited to this, and can be further modified.

For example, as shown in FIG. 7, the capsule body tllVc
A conductive contact piece 6υ is placed on the movable body (21), and while this contact piece ciIJ connects the conductor and Q~, the filament shown in Fig. 5 (51) is connected. When the moving body +21 moves to the right end of the capsule body txt and the contact piece 6υ connects the conductor and (to) j
Portions corresponding to the contacts in the figure may be connected. In addition, by increasing the gap between the conductor wire and (c) in Fig. 6, the current supply to the filament +51 is immediately cut off as soon as the moving body (21) starts moving.
You may set it to 5 to reduce the burden on ML pond +91.

In addition, the space (white) is filled with a chemical solution, a relatively weak seal 6'lJ shown by a chain line is provided, and the filament is transmitted from outside the body. (A current of 511c is applied to fuse and cut the °C thread +41, and press the medicine g filled in the moving body (the °C space is closed by the movement of 21), thereby breaking the seal p2+ yal- and injecting the medicinal solution into the body. In the case of C, the opening (101) may not be provided.Also, the opening 0 ( ) 1 may be left as is, and the internal body σ after the drug solution is released into the body) the drug solution and the digestive fluid or digested product. The mixture may be collected through the opening (IOl). In other words, the release of the drug solution from the capsule and the collection of the digestive fluid or test substance may be performed continuously in the same capsule.

-1', filament) +51 The control circuit for flowing VC current is not limited to the circuit shown in Figure 5, but can also be a switch circuit that turns on in response to an external electric or magnetic control signal. Any circuit can be used as long as it is 6. A timer or the like may be disposed inside the capsule body Il+ without external control, and a switch may be turned on after a certain period of time to cause the flow to flow through the filament +5+ vc. Alternatively, a long thread may be attached to the capsule body 111, the thread may be gradually swallowed together with the capsule, the position of the capsule may be determined based on the amount of swallowed thread, and the point at which current is applied to the filament (5) may be determined. In addition, if a thin thread is attached to the capsule and swallowed through the mouth, the capsule may be recovered from the first mouthful.Also, if the capsule is tied with a thread.

You can send and receive information through this thread. The reinforcing body (6) may be made of glass. Further, the left fl11 portion (1h) of the capsule body +11 may be made of metal and used as part of the electric circuit of the battery +91.

[Brief explanation of drawings]

Fig. 1 is a sectional view of a medical capsule according to color j of the present invention, Fig. 2 is a sectional view showing the state of the capsule in Fig. 1 after operation, and Fig. 3 is a sectional view taken along the line 1n-tn in Fig. 1. A partial cross-sectional view of
Figure 4 is an enlarged front view of the filament part, Figure 5 is the first
The capsule electric circuit shown in the figure is a circuit diagram, and FIG. 6 is a plan view showing a modified example of the detector. In the symbols used in the drawings, tl+ is the capsule body, (2) is the movable body, (3) is the spring %14) is the locking thread, [5+ is the filament, and (61 is the filament reinforcement body). (7) is a moving object detector, +81t2 electric circuit part, (
9) is a battery.

Claims (1)

Claims: il+ A swallowable capsule body having an opening for collection of or release of a substance into the body. a movable body movably disposed within the capsule body to perform the collection or the release by movement within the capsule body; 5. A moving body detector disposed within the capsule body to detect that the moving body has moved to a predetermined position within the capsule body. A transmission circuit disposed within the 5IC force cell body to transmit a detection signal based on the # moving body detector to the outside of the body. A medical capsule characterized by comprising: